TRAPPIST: a robotic telescope dedicated to the study of planetary systems

We present here a new robotic telescope called TRAPPIST (TRAnsiting Planets and PlanetesImals Small Telescope). Equipped with a high-quality CCD camera mounted on a 0.6 meter light weight optical tube, TRAPPIST has been installed in April 2010 at the ESO La Silla Observatory (Chile), and is now beginning its scientific program. The science goal of TRAPPIST is the study of planetary systems through two approaches: the detection and study of exoplanets, and the study of comets. We describe here the objectives of the project, the hardware, and we present some of the first results obtained during the commissioning phase.Comment: To appear in Detection and Dynamics of Transiting Exoplanets, Proceedings of Haute Provence Observatory Colloquium (23-27 August 2010), eds. F. Bouchy, R.F. Diaz & C.Moutou, Platypus press 201

Dissociative attachment in HCl, DCl, and F2

Resonant scattering models, using nonlocal decay widths, are developed for dissociative attachment of slow electrons to diatomic molecules. Cross sections are obtained for HCl and DCl in several initial rotational and vibrational states, and the dependence of the average attachment cross section upon the rotational and vibrational temperature is examined. For F_2 the cross section for ground state molecules agrees well with experiment above 0.2 eV but shows no zero energy peak. The attachment cross section is higher for vibrationally excited molecules, but the enhancement is much less than that found in H_2 and HCl

Infant Serum and Maternal Milk Vitamin B-12 Are Positively Correlated in Kenyan Infant-Mother Dyads at 1-6 Months Postpartum, Irrespective of Infant Feeding Practice.

BackgroundVitamin B-12 is an essential nutrient required for many functions including DNA synthesis, erythropoiesis, and brain development. If maternal milk vitamin B-12 concentrations are low, infants may face elevated risks of deficiency when exclusively breastfed.ObjectiveWe evaluated cross-sectional associations between infant serum vitamin B-12 concentrations and maternal milk vitamin B-12 concentrations at 1-6 mo postpartum among an unsupplemented population in rural western Kenya, and assessed biological demographic, and dietary characteristics associated with adequate infant serum vitamin B-12.MethodsWe modeled 1) infant serum vitamin B-12 using maternal milk vitamin B-12 concentration with linear regression; and 2) adequate (>220 pmol/L) infant serum vitamin B-12 using hypothesized biological, demographic, and dietary predictors with logistic regression. In both models, we used generalized estimating equations to account for correlated observations at the cluster-level.ResultsThe median (quartile 1, quartile 3) infant serum vitamin B-12 concentration was 276 pmol/L (193, 399 pmol/L) and approximately one-third of infants had serum vitamin B-12 ≤220 pmol/L, indicating that they were vitamin B-12 depleted or deficient. There was a positive correlation between maternal milk and infant serum vitamin B-12 (r = 0.36, P < 0.001) and in multivariable analyses, maternal milk vitamin B-12 concentration was significantly associated with infant serum vitamin B-12 adequacy (P-trend = 0.03).ConclusionsDespite a high prevalence (90%) of maternal milk vitamin B-12 concentrations below the level used to establish the Adequate Intake (<310 pmol/L), there was a low prevalence of infant vitamin B-12 deficiency. We found few factors that were associated with infant vitamin B-12 adequacy in this population, including infant feeding practices, although maternal vitamin B-12 status was not measured. The contribution of maternal milk to infant vitamin B-12 status remains important to quantify across populations, given that maternal milk vitamin B-12 concentration is modifiable with supplementation. This trial was registered at clinicaltrials.gov as NCT01704105

COSMOGRAIL: the COSmological MOnitoring of GRAvItational Lenses IX. Time delays, lens dynamics and baryonic fraction in HE 0435-1223

We present accurate time delays for the quadruply imaged quasar HE 0435-1223. The delays were measured from 575 independent photometric points obtained in the R-band between January 2004 and March 2010. With seven years of data, we clearly show that quasar image A is affected by strong microlensing variations and that the time delays are best expressed relative to quasar image B. We measured Delta_t(BC) = 7.8+/-0.8 days, Delta_t(BD) = -6.5+/-0.7 days and Delta_t_CD = -14.3+/-0.8 days. We spacially deconvolved HST NICMOS2 F160W images to derive accurate astrometry of the quasar images and to infer the light profile of the lensing galaxy. We combined these images with a stellar population fitting of a deep VLT spectrum of the lensing galaxy to estimate the baryonic fraction, $f_b$, in the Einstein radius. We measured f_b = 0.65+0.13-0.10 if the lensing galaxy has a Salpeter IMF and f_b = 0.45+0.04-0.07 if it has a Kroupa IMF. The spectrum also allowed us to estimate the velocity dispersion of the lensing galaxy, sigma_ap = 222+/-34 km/s. We used f_b and sigma_ap to constrain an analytical model of the lensing galaxy composed of an Hernquist plus generalized NFW profile. We solve the Jeans equations numerically for the model and explored the parameter space under the additional requirement that the model must predict the correct astrometry for the quasar images. Given the current error bars on f_b and sigma_ap, we did not constrain H0 yet with high accuracy, i.e., we found a broad range of models with chi^2 < 1. However, narrowing this range is possible, provided a better velocity dispersion measurement becomes available. In addition, increasing the depth of the current HST imaging data of HE 0435-1223 will allow us to combine our constraints with lens reconstruction techniques that make use of the full Einstein ring that is visible in this object.Comment: 12 pages, 10 figures, final version accepted for publication by A&

Multi-wavelength observations of afterglow of GRB 080319B and the modeling constraints

We present observations of the afterglow of GRB 080319B at optical, mm and radio frequencies from a few hours to 67 days after the burst. Present observations along with other published multi-wavelength data have been used to study the light-curves and spectral energy distributions of the burst afterglow. The nature of this brightest cosmic explosion has been explored based on the observed properties and it's comparison with the afterglow models. Our results show that the observed features of the afterglow fits equally good with the Inter Stellar Matter and the Stellar Wind density profiles of the circum-burst medium. In case of both density profiles, location of the maximum synchrotron frequency $\nu_m$ is below optical and the value of cooling break frequency $\nu_c$ is below $X-$rays, $\sim 10^{4}$s after the burst. Also, the derived value of the Lorentz factor at the time of naked eye brightness is $\sim 300$ with the corresponding blast wave size of $\sim 10^{18}$ cm. The numerical fit to the multi-wavelength afterglow data constraints the values of physical parameters and the emission mechanism of the burst.Comment: 8 Pages, 3 Figures, Accepted for publication to Astronomy and Astrophysics on 02/04/200

Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT

Ubiquitin-dependent mechanisms have emerged as essential regulatory elements controlling cellular levels of Smads and TGFß-dependent biological outputs such as epithelial–mesenchymal transition (EMT). In this study, we identify a HECT E3 ubiquitin ligase known as WWP2 (Full-length WWP2-FL), together with two WWP2 isoforms (N-terminal, WWP2-N; C-terminal WWP2-C), as novel Smad-binding partners. We show that WWP2-FL interacts exclusively with Smad2, Smad3 and Smad7 in the TGFß pathway. Interestingly, the WWP2-N isoform interacts with Smad2 and Smad3, whereas WWP2-C interacts only with Smad7. In addition, WWP2-FL and WWP2-C have a preference for Smad7 based on protein turnover and ubiquitination studies. Unexpectedly, we also find that WWP2-N, which lacks the HECT ubiquitin ligase domain, can also interact with WWP2-FL in a TGFß-regulated manner and activate endogenous WWP2 ubiquitin ligase activity causing degradation of unstimulated Smad2 and Smad3. Consistent with our protein interaction data, overexpression and knockdown approaches reveal that WWP2 isoforms differentially modulate TGFß-dependent transcription and EMT. Finally, we show that selective disruption of WWP2 interactions with inhibitory Smad7 can stabilise Smad7 protein levels and prevent TGFß-induced EMT. Collectively, our data suggest that WWP2-N can stimulate WWP2-FL leading to increased activity against unstimulated Smad2 and Smad3, and that Smad7 is a preferred substrate for WWP2-FL and WWP2-C following prolonged TGFß stimulation. Significantly, this is the first report of an interdependent biological role for distinct HECT E3 ubiquitin ligase isoforms, and highlights an entirely novel regulatory paradigm that selectively limits the level of inhibitory and activating Smads

On the evolution of environmental and mass properties of strong lens galaxies in COSMOS

Among the 100 strong lens candidates found in the COSMOS field, 20 with redshifts in the range [0.34,1.13], feature multiple images of background sources. Using the multi-wavelength coverage of the field and its spectroscopic follow-up, we characterize the evolution with redshift of the environment and of the dark-matter (DM) fraction of the lens galaxies. We present new redshift of the strong lens candidates. The lens environment is characterized by the projected 10 closest galaxies around each lens and by the number of galaxies with a projected distance less than 1Mpc at the lens galaxy redshift. In both cases, we perform similar measurements on a control sample of twin non-lens early type galaxies (ETGs). In addition, we identify group members and field galaxies in the X-ray and optical catalogs of galaxy groups. From those catalogs, we measure the external shear contribution at the lens galaxy positions. The systems are then modeled using a SIE plus the external shear due to the groups. We observe that the average stellar mass of lens galaxies increases with z and that the environment of lens galaxies is compatible with that of the twins. During the lens modeling, we notice that, when let free, the external shear points in a direction which is the mean direction of the external shear due to groups and of the closest galaxy to the lens. We notice that the DM fraction of the lens galaxies within the Einstein radius decreases as the redshift increases. Given these, we conclude that, while the environment of lens galaxies is compatible with that of non-lens ETGS, their mass properties evolves significantly with redshift: it is still not clear whether this advocates in favor of a stronger lensing bias toward massive objects at high redshift or is simply representative of the high proportion of massive and high stellar density galaxies at high redshift.Comment: Accepted for publication in A&A. Significant modifications in the paper but similar conclusion

Order-of-magnitude speedup for steady states and traveling waves via Stokes preconditioning in Channelflow and Openpipeflow

Steady states and traveling waves play a fundamental role in understanding hydrodynamic problems. Even when unstable, these states provide the bifurcation-theoretic explanation for the origin of the observed states. In turbulent wall-bounded shear flows, these states have been hypothesized to be saddle points organizing the trajectories within a chaotic attractor. These states must be computed with Newton's method or one of its generalizations, since time-integration cannot converge to unstable equilibria. The bottleneck is the solution of linear systems involving the Jacobian of the Navier-Stokes or Boussinesq equations. Originally such computations were carried out by constructing and directly inverting the Jacobian, but this is unfeasible for the matrices arising from three-dimensional hydrodynamic configurations in large domains. A popular method is to seek states that are invariant under numerical time integration. Surprisingly, equilibria may also be found by seeking flows that are invariant under a single very large Backwards-Euler Forwards-Euler timestep. We show that this method, called Stokes preconditioning, is 10 to 50 times faster at computing steady states in plane Couette flow and traveling waves in pipe flow. Moreover, it can be carried out using Channelflow (by Gibson) and Openpipeflow (by Willis) without any changes to these popular spectral codes. We explain the convergence rate as a function of the integration period and Reynolds number by computing the full spectra of the operators corresponding to the Jacobians of both methods.Comment: in Computational Modelling of Bifurcations and Instabilities in Fluid Dynamics, ed. Alexander Gelfgat (Springer, 2018