Existence of initial data satisfying the constraints for the spherically symmetric Einstein-Vlasov-Maxwell system

Using ODE techniques we prove the existence of large classes of initial data satisfying the constraints for the spherically symmetric Einstein-Vlasov-Maxwell system. These include data for which the ratio of total charge to total mass is arbitrarily large.Comment: 12 page

Identifying and Indexing Icosahedral Quasicrystals from Powder Diffraction Patterns

We present a scheme to identify quasicrystals based on powder diffraction data and to provide a standardized indexing. We apply our scheme to a large catalog of powder diffraction patterns, including natural minerals, to look for new quasicrystals. Based on our tests, we have found promising candidates worthy of further exploration.Comment: 4 pages, 1 figur

Self-Diffusion in Random-Tiling Quasicrystals

The first explicit realization of the conjecture that phason dynamics leads to self-diffusion in quasicrystals is presented for the icosahedral Ammann tilings. On short time scales, the transport is found to be subdiffusive with the exponent $\beta\approx0.57(1)$, while on long time scales it is consistent with normal diffusion that is up to an order of magnitude larger than in the typical room temperature vacancy-assisted self-diffusion. No simple finite-size scaling is found, suggesting anomalous corrections to normal diffusion, or existence of at least two independent length scales.Comment: 11 pages + 2 figures, COMPRESSED postscript figures available by anonymous ftp to black_hole.physics.ubc.ca directory outgoing/diffuse (use bi for binary mode to transfer), REVTeX 3.0, CTP-TAMU 21/9

Hematopoietic stem cell transplantation in Europe 2014: More than 40 000 transplants annually

A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant activity, more so in Eastern European countries than in the west; a continued increase in the use of haploidentical family donors (by 25%) and slower growth for unrelated donor HSCT. The use of cord blood as a stem cell source has decreased again in 2014. Main indications for HSCT were leukemias: 11 853 (33%; 96% allogeneic); lymphoid neoplasias; 20 802 (57%; 11% allogeneic); solid tumors; 1458 (4%; 3% allogeneic) and non-malignant disorders; 2203 (6%; 88% allogeneic). Changes in transplant activity include more allogeneic HSCT for AML in CR1, myeloproliferative neoplasm (MPN) and aplastic anemia and decreasing use in CLL; and more autologous HSCT for plasma cell disorders and in particular for amyloidosis. In addition, data on numbers of teams doing alternative donor transplants, allogeneic after autologous HSCT, autologous cord blood transplants are presented

Vortex-unbinding and finite-size effects in Tl2Ba2CaCu2O8 thin films

Current-voltage ($I$-$V$) characteristics of Tl$_2$Ba$_2$CaCu$_2$O$_8$ thin films in zero magnetic field are measured and analyzed with the conventional Kosterlitz-Thouless-Berezinskii (KTB) approach, dynamic scaling approach and finite-size scaling approach, respectively. It is found from these results that the $I$-$V$ relation is determined by the vortex-unbinding mechanism with the KTB dynamic critical exponent $z=2$. On the other hand, the evidence of finite-size effect is also found, which blurs the feature of a phase transition.Comment: Typo corrected & reference adde

The Cauchy Problem for the Einstein Equations

Various aspects of the Cauchy problem for the Einstein equations are surveyed, with the emphasis on local solutions of the evolution equations. Particular attention is payed to giving a clear explanation of conceptual issues which arise in this context. The question of producing reduced systems of equations which are hyperbolic is examined in detail and some new results on that subject are presented. Relevant background from the theory of partial differential equations is also explained at some lengthComment: 98 page

Effects and safety of rituximab in systemic sclerosis: An analysis from the European Scleroderma Trial and Research (EUSTAR) group

Objectives: To assess the effects of Rituximab (RTX) on skin and lung fibrosis in patients with systemic sclerosis (SSc) belonging to the European Scleroderma Trial and Research (EUSTAR) cohort and using a nested case-control design. Methods: Inclusion criteria were fulfilment of American College of Rheumatology classification criteria for SSc, treatment with RTX and availability of follow-up data. RTX-treated patients were matched with control patients from the EUSTAR database not treated with RTX. Matching parameters for skin/lung fibrosis were the modified Rodnan Skin Score (mRSS), forced vital capacity (FVC), follow-up duration, scleroderma subtype, disease duration and immunosuppressive co-treatment. The primary analysis was mRSS change from baseline to follow-up in the RTX group compared with the control group. Secondary analyses included change of FVC and safety measures. Results: 63 patients treated with RTX were included in the analysis. The case-control analysis in patients with severe diffuse SSc showed that mRSS changes were larger in the RTX group versus matched controls (N=25; -24.0±5.2% vs-7.7±4.3%; p=0.03). Moreover, in RTX-treated patients, the mean mRSS was significantly reduced at follow-up compared with baseline (26.6±1.4 vs 20.3±1.8; p=0.0001). In addition, in patients with interstitial lung disease, RTX prevented significantly the further decline of FVC compared with matched controls (N=9; 0.4±4.4% vs-7.7±3.6%; p=0.02). Safety measures showed a good profile consistent with previous studies in autoimmune rheumatic diseases. Conclusions: The comparison of RTX treated versus untreated matched-control SSc patients from the EUSTAR cohort demonstrated improvement of skin fibrosis and prevention of worsening lung fibrosis, supporting the therapeutic concept of B cell inhibition in SSc

Tracing the ancestry of modern bread wheats

For more than 10,000 years, the selection of plant and animal traits that are better tailored for human use has shaped the development of civilizations. During this period, bread wheat (Triticum aestivum) emerged as one of the world’s most important crops. We use exome sequencing of a worldwide panel of almost 500 genotypes selected from across the geographical range of the wheat species complex to explore how 10,000 years of hybridization, selection, adaptation and plant breeding has shaped the genetic makeup of modern bread wheats. We observe considerable genetic variation at the genic, chromosomal and subgenomic levels, and use this information to decipher the likely origins of modern day wheats, the consequences of range expansion and the allelic variants selected since its domestication. Our data support a reconciled model of wheat evolution and provide novel avenues for future breeding improvement.</p