47 research outputs found

    Literature Review on Vague Set Theory in Different Domains

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    Problem of decision making is a crucial task in every business. This decision making job is found very difficult when it is depends on the imprecise and vague environment, which is frequent in recent years. Vague sets are an extension of Fuzzy sets. In the fuzzy sets, each object is assigned a single value in the interval [0,1] reflecting its grade of membership. This single value does not allow a separation of evidence for membership and evidence against membership. Gau et al. proposed the notion of vague sets, where each object is characterized by two different membership functions: a true membership function and a false membership function. This kind of reasoning is also called interval membership, as opposed to point membership in the context of fuzzy sets. In this paper, reviews the related works on the decision making by using vague sets in different fields

    Indian Financial Systems and Stockmarkets During COVID 19- Shape off Post Covid Through AI and Other Digital Tools

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    Introduction: Apart from the loss of precious lives, COVID-19 pandemic caused setbacks to all the developmental works, progress of the economy of all countries with serious repercussions on financial systems and stock markets. Most economies, including Indian stock markets since recovered from the shock, showing robustness due to stringent regulatory framework, started rebuilding, from the vertical fall. India as a nation had sufficient leeway to respond to the crisis and market instability, due to its inner strength. Aim: This is a theoretical study of the reaction of stock markets, also of expansionary monetary policies during pandemic, the resurgence of financial system and recovery of Indian stock markets, with extreme adoption of Digital tools like AI for Algo trading . Method: Secondary research methods have been adopted, for analyzing conceptual approaches of regulatory frameworks of the Securities market, Central bank, amid volatility, to draw conclusions. The stock market data (NSE) is subjected to VaR test. Findings: The Study finds that country has responded quickly to the outbreak of the crisis by easing capital and liquidity requirements or at least refraining from the previously planned tightening. At the same time, the authors noticed that loan-based measures and minimum reserve requirements were rarely relaxed and risk weights were not changed at all. Digital tools like Algo trading, AI based advisory gained prominence Conclusion: The impact of novel coronavirus (COVID-19) pandemic on financial system and the stock markets in India, is significant. But Monetary policy, liquidity operations and aid packages that were offered by the Government have minimized the impact to a large extent and brought the financial systems back onto the rail. Key Words: Corona Virus, Financial Markets, Stock market, Algo trade

    Adult chordoid meningioma: a case report

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    Chordoid meningioma is a rare tumour accounting for less than 0.5% of all meningiomas. It is a WHO grade II tumour with an aggressive behavior. It is a rare variant characterized by cords or trabeculae of eosinophilic or vacuolated cells set in an abundant mucoid matrix. It can be associated with systemic or hematologic manifestations like Castleman disease. The tumor has a propensity for aggressive behavior and increased likelihood of recurrence We report a case of an adult patient with chordoid meningioma who presented with headache and seizures and did not have any hematological/ systemic manifestations. She underwent total excision of the lesion and is doing well

    Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

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    Background Results of small trials indicate that fluoxetine might improve functional outcomes after stroke. The FOCUS trial aimed to provide a precise estimate of these effects. Methods FOCUS was a pragmatic, multicentre, parallel group, double-blind, randomised, placebo-controlled trial done at 103 hospitals in the UK. Patients were eligible if they were aged 18 years or older, had a clinical stroke diagnosis, were enrolled and randomly assigned between 2 days and 15 days after onset, and had focal neurological deficits. Patients were randomly allocated fluoxetine 20 mg or matching placebo orally once daily for 6 months via a web-based system by use of a minimisation algorithm. The primary outcome was functional status, measured with the modified Rankin Scale (mRS), at 6 months. Patients, carers, health-care staff, and the trial team were masked to treatment allocation. Functional status was assessed at 6 months and 12 months after randomisation. Patients were analysed according to their treatment allocation. This trial is registered with the ISRCTN registry, number ISRCTN83290762. Findings Between Sept 10, 2012, and March 31, 2017, 3127 patients were recruited. 1564 patients were allocated fluoxetine and 1563 allocated placebo. mRS data at 6 months were available for 1553 (99·3%) patients in each treatment group. The distribution across mRS categories at 6 months was similar in the fluoxetine and placebo groups (common odds ratio adjusted for minimisation variables 0·951 [95% CI 0·839–1·079]; p=0·439). Patients allocated fluoxetine were less likely than those allocated placebo to develop new depression by 6 months (210 [13·43%] patients vs 269 [17·21%]; difference 3·78% [95% CI 1·26–6·30]; p=0·0033), but they had more bone fractures (45 [2·88%] vs 23 [1·47%]; difference 1·41% [95% CI 0·38–2·43]; p=0·0070). There were no significant differences in any other event at 6 or 12 months. Interpretation Fluoxetine 20 mg given daily for 6 months after acute stroke does not seem to improve functional outcomes. Although the treatment reduced the occurrence of depression, it increased the frequency of bone fractures. These results do not support the routine use of fluoxetine either for the prevention of post-stroke depression or to promote recovery of function. Funding UK Stroke Association and NIHR Health Technology Assessment Programme

    Adult chordoid meningioma: a case report

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    Chordoid meningioma is a rare tumour accounting for less than 0.5% of all meningiomas. It is a WHO grade II tumour with an aggressive behavior. It is a rare variant characterized by cords or trabeculae of eosinophilic or vacuolated cells set in an abundant mucoid matrix. It can be associated with systemic or hematologic manifestations like Castleman disease. The tumor has a propensity for aggressive behavior and increased likelihood of recurrence We report a case of an adult patient with chordoid meningioma who presented with headache and seizures and did not have any hematological/ systemic manifestations. She underwent total excision of the lesion and is doing well

    Removal of Toluidine blue in water using green synthesized nanomaterials

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    Green synthesis is a simple, eco-friendly, and emerging approach to synthesizing nanoparticles and is currently attracting the scientific community worldwide. The objective of the present study was to synthesize green titanium dioxide NPs and evaluate their performance for the photocatalytic treatment of textile wastewater after the secondary treatment process. TiO2 NPs were synthesized using leaf extracts of asausage tree (Kigelia Africana) in asingle step. The green synthesized TiO2 NPs were characterized by Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectroscopy (EDX), X-Ray Diffraction (XRD), Fourier-Transform Infrared spectroscopy (FT-IR), Diffuse Light Scattering spectroscopy (DLS), Transmission Electron Microscopy (TEM). The findings validated the synthesis of the spherical-shaped TiO2 NPs and their anatase phase. The green-produced TiO2 NPs were used for the treatment of textile effluent. During the photocatalytic treatment of aself-designed dye solution, 99.59% removal of Toluidine blue(TB) dye was achieved within 60 minupon the treatment of green synthesized TiO2 NPs studied by a UV–Visible spectrophotometer. Therefore, the green TiO2NPs that were developed have been examined for the treatment of wastewater, and the catalyst has reusability make it more efficient and affordable, and it might be used to remove organic dyes from textile industrie

    A simple and cost effective technique for construction of tissue microarrays

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    Background: Tissue microarray is widely used in histopathology and biomedical research. Construction of tissue microarray can help institutes to considerably reduce, cost of consumables, skilled man power needed and time needed in performing high output research. However resource poor centers in developing countries have hardly any access to such techniques.  The aim of this research is to develop simple, cost effective technique for making tissue microarray.Materials and methods: Materials available in a standard pathology laboratory such as skin punch biopsy needle, bone marrow aspiration needle, trephine biopsy needle, stylet, paraffin wax, hot air oven, slide warming table, drawing pin and measuring scale were used in developing this tissue microarray. The tissue array thus developed was sectioned using a standard microtome. Immunohistochemical studies were also performed on these tissue array sections which yielded satisfactory results.Results: This technique for construction of TMAs is simple and cost effective. When 3.5 to 3mm cores were used we were able to construct arrays up to 32 cores in one block. When 1mm cores were used we were able to construct arrays with 100 representative cores in one block. Morphological identification, histological typing and grading could be done in TMA sectionsConclusion: Tissue microarray is a relatively recent innovation in the field of pathology. We hope that our technique will encourage the younger researchers to take up research projects of large sample size requiring molecular studies with significantly lesser economic burden and thus leading to a significant acceleration in the transition of basic research findings into clinical applications.</p

    Kinetic and Mechanistic Parameters of Laccase Catalyzed Direct Electrochemical Oxygen Reduction Reaction

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    This article presents the kinetic studies of oxygen reduction by one of the most important multicopper oxidases (fungal laccase) using the classic tool of electrochemistry: rotating ring-disk electrode (RRDE). Laccase was immobilized on a multiwalled carbon nanotube (MWNT) modified inert disk electrode using 1-pyrenebutanoic acid succinimidyl ester (PBSE), as a tethering agent. The conditions for laccase immobilization on MWNT were optimized to prepare a highly active composite electro-catalyst for O<sub>2</sub> reduction. The mechanistic as well as kinetic parameters such as Tafel slopes, number of electrons transferred, electrochemical rate constants (for heterogeneous charge transfer) and electron transfer rate constant were calculated from the RRDE experiment results. The Tafel slope obtained was close to the value of that of ideal four-electron reduction of O<sub>2</sub> to water indicating a highly active laccase in the tethered composite. The RRDE results also suggested the presence of intermediate steps in the oxygen reduction reaction. A model pathway for O<sub>2</sub> reduction reaction at the laccase composite modified electrode was postulated, and rate constants for individual reactions in the pathway were calculated. The rate constant for four-electron O<sub>2</sub> reduction was determined to be 1.46 × 10<sup>–3</sup> mol s<sup>–1</sup>, indicating excellent electro-catalytic activity of the laccase-MWNT composite catalyst
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