6,774 research outputs found
The effect of TelfastÂź 180 on driver behaviour, decision-making and reaction time.
The principal objective of the study was to examine the effect of TelfastÂź 180, an antihistamine, on driver behaviour, decision-making, and reaction time. A sample of 255 volunteers participated in the study. The sample was randomly divided into two groups, viz. a placebo and a Telfast group. One of the groups received Telfast and the other a placebo. Initially all the participants were given a standardised driving test, as well as a psychomotor test. Immediately thereafter the placebo group received their placebo tablets and the Telfast group their Telfast tablets. Exactly 2,6 hours later every participant was tested again, using the same tests as before. No statistically significant differences were found between the Placebo group and the Telfast group. No sedative effects due to TelfastÂź 180 were thus evident
Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT)
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors? What evidence supports its adoption? How can this evidence best be used? This review addresses these questions and provides an understanding of FIT theory and practices to expedite international efforts to implement the use of FIT in CRC screening
Searching for plasticity in dissociated cortical cultures on multi-electrode arrays
We attempted to induce functional plasticity in dense cultures of cortical cells using stimulation through extracellular electrodes embedded in the culture dish substrate (multi-electrode arrays, or MEAs). We looked for plasticity expressed in changes in spontaneous burst patterns, and in array-wide response patterns to electrical stimuli, following several induction protocols related to those used in the literature, as well as some novel ones. Experiments were performed with spontaneous culture-wide bursting suppressed by either distributed electrical stimulation or by elevated extracellular magnesium concentrations as well as with spontaneous bursting untreated. Changes concomitant with induction were no larger in magnitude than changes that occurred spontaneously, except in one novel protocol in which spontaneous bursts were quieted using distributed electrical stimulation
Coherent Optimal Control of Multiphoton Molecular Excitation
We give a framework for molecular multiphoton excitation process induced by
an optimally designed electric field. The molecule is initially prepared in a
coherent superposition state of two of its eigenfunctions. The relative phase
of the two superposed eigenfunctions has been shown to control the optimally
designed electric field which triggers the multiphoton excitation in the
molecule. This brings forth flexibility in desiging the optimal field in the
laboratory by suitably tuning the molecular phase and hence by choosing the
most favorable interfering routes that the system follows to reach the target.
We follow the quantum fluid dynamical formulation for desiging the electric
field with application to HBr molecule.Comment: 5 figure
Resistance of a domain wall in the quasiclassical approach
Starting from a simple microscopic model, we have derived a kinetic equation
for the matrix distribution function. We employed this equation to calculate
the conductance in a mesoscopic F'/F/F' structure with a domain wall (DW).
In the limit of a small exchange energy and an abrupt DW, the conductance
of the structure is equal to . Assuming that the scattering times
for electrons with up and down spins are close to each other we show that the
account for a finite width of the DW leads to an increase in this conductance.
We have also calculated the spatial distribution of the electric field in the F
wire. In the opposite limit of large (adiabatic variation of the
magnetization in the DW) the conductance coincides in the main approximation
with the conductance of a single domain structure . The account for rotation of
the magnetization in the DW leads to a negative correction to this conductance.
Our results differ from the results in papers published earlier.Comment: 11 pages; replaced with revised versio
Hydrodynamics near the QCD Phase Transition: Looking for the Longest-Lived Fireball
We propose a new strategy for the experimental search of the QCD phase
transition in heavy ion collisions: One may tune collision energy around the
point where the lifetime of the fireball is expected to be longest. We
demonstrate that the hydrodynamic evolution of excited nuclear matter does
change dramatically as the initial energy density goes through the "softest
point" (where the pressure to energy density ratio reaches its minimum). For
our choice of equation of state, this corresponds to epsilon_i approx. = 1.5
GeV/fm^3 and collision energy E_lab/A approx. = 30 GeV (for Au+Au). Various
observables seem to show distinct changes near the softest point.Comment: 7 pages, 3 Postscript figures (tar compressed and uuencoded)
submitte
Practitioner accounts and knowledge production: an analysis of three marketing discourses
Responding to repeated calls for marketing academicians to connect with marketing actors, we offer an empirically-sourced discourse analysis of the ways in which managers portray their practices. Focusing on the micro-discourses and narratives that marketing actors draw upon to represent their work we argue that dominant representations of marketing knowledge production present a number of critical concerns for marketing theory and marketing education. We also evidence that the often promoted idea of a need to close the gap between theory - as a dominant discourse - and practice, as a way of doing marketing, is problematic to pursue. We suggest that a more fruitful agenda resides in the development of a range of polyphonic and creative micro-discourses of management, promoting context, difference and individual meaning in marketing knowledge production
Observational Constraints on Interstellar Grain Alignment
We present new multicolor photo-polarimetry of stars behind the Southern
Coalsack. Analyzed together with multiband polarization data from the
literature, probing the Chamaeleon I, Musca, rho Opiuchus, R CrA and Taurus
clouds, we show that the wavelength of maximum polarization (lambda_max) is
linearly correlated with the radiation environment of the grains. Using
Far-Infrared emission data, we show that the large scatter seen in previous
studies of lambda_max as a function of A_V is primarily due to line of sight
effects causing some A_V measurements to not be a good tracer of the extinction
(radiation field strength) seen by the grains being probed. The derived slopes
in lambda_max vs. A_V, for the individual clouds, are consistent with a common
value, while the zero intercepts scale with the average values of the ratios of
total-to-selective extinction (R_V) for the individual clouds. Within each
cloud we do not find direct correlations between lambda_max and R_V. The
positive slope in consistent with recent developments in theory and indicating
alignment driven by the radiation field. The present data cannot conclusively
differentiate between direct radiative torques and alignment driven by H_2
formation. However, the small values of lambda_max(A_V=0), seen in several
clouds, suggest a role for the latter, at least at the cloud surfaces. The
scatter in the lambda_max vs. A_V relation is found to be associated with the
characteristics of the embedded Young Stellar Objects (YSO) in the clouds. We
propose that this is partially due to locally increased plasma damping of the
grain rotation caused by X-rays from the YSOs.Comment: Accepted for publication in the Astrophysical Journa
WormBase 2007
WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence information, WormBase now includes the genomic, anatomical and functional information about C. elegans, other Caenorhabditis species and other nematodes. As such, it is a crucial resource not only for C. elegans biologists but the larger biomedical and bioinformatics communities. Coverage of core areas of C. elegans biology will allow the biomedical community to make full use of the results of intensive molecular genetic analysis and functional genomic studies of this organism. Improved search and display tools, wider cross-species comparisons and extended ontologies are some of the features that will help scientists extend their research and take advantage of other nematode species genome sequences
Formalising the Continuous/Discrete Modeling Step
Formally capturing the transition from a continuous model to a discrete model
is investigated using model based refinement techniques. A very simple model
for stopping (eg. of a train) is developed in both the continuous and discrete
domains. The difference between the two is quantified using generic results
from ODE theory, and these estimates can be compared with the exact solutions.
Such results do not fit well into a conventional model based refinement
framework; however they can be accommodated into a model based retrenchment.
The retrenchment is described, and the way it can interface to refinement
development on both the continuous and discrete sides is outlined. The approach
is compared to what can be achieved using hybrid systems techniques.Comment: In Proceedings Refine 2011, arXiv:1106.348
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