703 research outputs found

    Turismo cultural, patrimonio inmaterial y elementos que inciden en la diferente satisfacción del visitante a partir del estudio del sombrero de paja toquilla

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    Pese a que existen varias aproximaciones a la relación entre patrimonio, características del turista y satisfacción, aún son necesarias interpretaciones más complejas, que indaguen en la comparación simultánea de variables de naturaleza diversa. En este sentido, el presente estudio busca dar una interpretación a las diferencias en cuanto a la valoración de los distintos ítems vinculados a la satisfacción de los turistas mediante la utilización de variables sociodemográficas, sociolaborales y de conocimiento previo sobre el destino, buscando identificar cuáles son más importantes. Estas cuestiones se aplican a un ámbito relativamente poco estudiado, como son las ciudades medias latinoamericanas que gozan de un reconocimiento como Ciudades Patrimonio Cultural de la Humanidad y, además, acogen un Patrimonio Cultural Inmaterial también reconocido por la Unesco, elemento hacia el que se enfoca este trabajo. Para ello, se analizan e interpretan los resultados de una encuesta realizada en la ciudad de Cuenca (Ecuador) utilizando pruebas de normalidad. Los resultados ponen de manifiesto que el conocimiento previo del destino turístico y su condición de Patrimonio material o inmaterial son las cuestiones más significativas que influyen en la satisfacción del turista y el deseo de regresar.

    La representación social de una actividad productiva como contexto y apoyo de la acción sindical. Los astilleros gaditanos en las coplas del carnaval

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    Las numerosas movilizaciones de los trabajadores de los astilleros de la Bahía de Cádiz han suscitado siempre amplios movimientos de solidaridad por parte de la población de la zona. Esto ha constituido un importante recurso para los sindicatos a la hora de presionar al Gobierno, no sólo para minimizar los efectos de las reconversiones, sino, sobre todo, para evitar el cierre o la privatización de los astilleros de la Bahía. El objeto de este artículo es profundizar en los motivos que explican estas reacciones de solidaridad, partiendo de que, dado que la relevancia económica del sector naval es reducida desde hace años, la clave del apoyo de la población se encuentra más bien en la importancia simbólica que los gaditanos atribuyen a esta actividad. Para ello, utilizamos una peculiar fuente de información: las coplas del Carnaval de Cádiz

    Assemblage urbanism:The role of heritage in urban placemaking

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    Purpose The paper explores the potential value of urban assemblage theory as a conceptual framework for understanding the role heritage has in social sustainable urban placemaking. The authors conceptualise urban placemaking as a dynamic and complex social assemblage. Heritage is one of the many dimensions of such a complex and dynamic urban assembly. Based on the approach to urban assemblage theory, the authors aim to uncover how postindustrial city-making unfolds. When approaching the case studies, the authors ask the following: Whose city for which citizens are visible through the selected case studies? How is social sustainability achieved through heritage in urban placemaking? Design/methodology/approach The main research material is derived from theoretical literature and the testing of an assemblage methodological approach through three Norwegian urban regeneration case studies where heritage partake in urban placemaking. The three case studies are the Tukthus wall (what is left of an 19th century old prison), the Vulkan neighbourhood (an 19th century industrial working area) and Sørengkaia (an 19th century industrial harbour area) in Oslo, Norway. The three case studies are representing urban regeneration projects which are common worldwide, and not at least in a European context. Findings The paper reveals the dynamic factors and processes at play in urban placemaking, which has its own distinct character by the uses of heritage in each of the case study areas. Placemaking could produce “closed” systems which are stable in accordance with its original functions, or they could be “open” systems affected by the various drivers of change. The paper shows how these forces are depending on two sets of binary forces at play in urban placemaking: forces of “assemblages” co-creating a place versus destabilising forces of “disassembly” which is redefining the place as a process affected by reassembled placemaking. Research limitations/implications For research, the authors focus on the implications this paper has for the field of urban heritage studies as it provides a useful framework to capture the dynamic complexity of urban heritage areas. Practical implications For practice, the authors state that the paper can provide a useful platform for dialogue and critical thinking on strategies being planned. Social implications For society, the paper promotes the significance in terms of fostering an inclusive way of thinking and planning for urban heritage futures. Originality/value The paper outlines dynamics of urban regeneration through heritage which are significant for understanding urban transformation as value for offering practical solutions to social problems in urban planning. The assemblage methodological approach (1) makes awareness of the dynamic processes at play in urban placemaking and makes the ground for mapping issue at stake in urban placemaking; (2) becomes a source for modelling urban regeneration through heritage by defining a conceptual framework of dynamic interactions in urban placemaking; and (3) defines a critically reflexive tool for evaluating good versus bad (heritage-led) urban development projects

    Diagnóstico de seguridad e higiene en los laboratorios del Departamento de Química de la Universidad Nacional Autónoma de Nicaragua UNAN-Managua RURD, durante el período de Julio a Octubre del 2011

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    El tema que se pretende desarrollar tiene como título “Diagnóstico de Seguridad e Higiene en los Laboratorios del Departamento de Química de la Universidad Nacional Autónoma de Nicaragua (UNAN-Managua RURD)”. El propósito del estudio es concebir y desarrollar un programa que corrija de manera eficiente el incumplimiento de la Legislación Nacional sobre Seguridad a corto y largo plazo. Surge de la importancia que representa el poder mantener un ambiente laboral lo más sano posible, en el que el trabajador se sienta seguro para poder realizar sus actividades con mucha eficiencia y un óptimo desempeño. Satisfacer las necesidades de seguridad y protección de los docentes y estudiantes implicados en la realización de las prácticas de laboratorio en el departamento de Química, así como la formación relacionada a adquirir una conciencia como individuo en función de la salud y seguridad de las personas involucradas en la actividad educativa y formativa. Dentro de su elaboración se comprende la evaluación de las condiciones en las que se realizan las prácticas, así como el manejo de materiales y el tratamiento de los residuos y desechos generados durante las mismas. Para esto es necesario contar primero con el RTO del Departamento de Química, lo cual orientará las normas y pautas a seguir durante la realización de las prácticas o durante su estancia en los laboratorios o visitas a estos. Seguidamente se evaluaran la probabilidad del riesgo y su respectiva severidad para ser reflejadas en la matriz de riesgos elaborada de manera general para todos los laboratorios, a continuación y en base a los riesgos identificados se realiza el mapeo de los mismos mediante la representación en planta de cada laboratorio. Se realizará un plan de contingencia o de acción en caso de que se presente un desastre dentro de las instalaciones, los cuales puedan ser: sismos, derrames, incendio, etc. además de lo anterior se procede a elaborar un plan ambiental donde se visualice de forma esquematizada el proceso de realización de las practicas logrando identificar las entradas, el proceso y las salidas del mismo, para poder tratar de esa manera los desechos que se generan y reutilizar los desperdicios

    Assemblage urbanism: the role of heritage in urban placemaking

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    Purpose: The paper explores the potential value of urban assemblage theory as a conceptual framework for understanding the role heritage has in social sustainable urban placemaking. The authors conceptualise urban placemaking as a dynamic and complex social assemblage. Heritage is one of the many dimensions of such a complex and dynamic urban assembly. Based on the approach to urban assemblage theory, the authors aim to uncover how postindustrial city-making unfolds. When approaching the case studies, the authors ask the following: Whose city for which citizens are visible through the selected case studies? How is social sustainability achieved through heritage in urban placemaking? Design/methodology/approach: The main research material is derived from theoretical literature and the testing of an assemblage methodological approach through three Norwegian urban regeneration case studies where heritage partake in urban placemaking. The three case studies are the Tukthus wall (what is left of an 19th century old prison), the Vulkan neighbourhood (an 19th century industrial working area) and Sørengkaia (an 19th century industrial harbour area) in Oslo, Norway. The three case studies are representing urban regeneration projects which are common worldwide, and not at least in a European context. Findings: The paper reveals the dynamic factors and processes at play in urban placemaking, which has its own distinct character by the uses of heritage in each of the case study areas. Placemaking could produce “closed” systems which are stable in accordance with its original functions, or they could be “open” systems affected by the various drivers of change. The paper shows how these forces are depending on two sets of binary forces at play in urban placemaking: forces of “assemblages” co-creating a place versus destabilising forces of “disassembly” which is redefining the place as a process affected by reassembled placemaking. Research limitations/implications: For research, the authors focus on the implications this paper has for the field of urban heritage studies as it provides a useful framework to capture the dynamic complexity of urban heritage areas. Practical implications: For practice, the authors state that the paper can provide a useful platform for dialogue and critical thinking on strategies being planned. Social implications: For society, the paper promotes the significance in terms of fostering an inclusive way of thinking and planning for urban heritage futures. Originality/value: The paper outlines dynamics of urban regeneration through heritage which are significant for understanding urban transformation as value for offering practical solutions to social problems in urban planning. The assemblage methodological approach (1) makes awareness of the dynamic processes at play in urban placemaking and makes the ground for mapping issue at stake in urban placemaking; (2) becomes a source for modelling urban regeneration through heritage by defining a conceptual framework of dynamic interactions in urban placemaking; and (3) defines a critically reflexive tool for evaluating good versus bad (heritage-led) urban development projects

    Uptake and intracellular activity of sparfloxacin in human polymorphonuclear leukocytes and tissue culture cells

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    The penetration of sparfloxacin into human neutrophils (PMN) and different tissue culture cells (HEp-2 and McCoy) was evaluated. The cellular to extracellular concentration ratios (C/E) of sparfloxacin were always higher than 4 at extracellular concentrations ranging from 0.5 to 25 mg/liter. The uptake of sparfloxacin by PMN was rapid, nonsaturable, reversible, not energy dependent, and significantly reduced at pH 8. The penetration of this agent into PMN was similar when viable and Formalin-killed cells were used and was not affected by environmental temperature. Ingestion of opsonized zymosan significantly increased the amount of PMN-associated sparfloxacin. Sparfloxacin at a concentration of 0.5 mg induced a significant reduction in the survival of intracellular Staphylococcus aureus. It is concluded that sparfloxacin reaches intracellular concentrations within leukocytic cells much higher than extracellular concentrations, while remaining active intracellularly

    The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E

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    Schwann cell factor 1 (SC1), a p75 neurotrophin receptor–interacting protein, is a member of the positive regulatory/suppressor of variegation, enhancer of zeste, trithorax (PR/SET) domain-containing zinc finger protein family, and it has been shown to be regulated by serum and neurotrophins. SC1 shows a differential cytoplasmic and nuclear distribution, and its presence in the nucleus correlates strongly with the absence of bromodeoxyuridine (BrdU) in these nuclei. Here, we investigated potential transcriptional activities of SC1 and analyzed the function of its various domains. We show that SC1 acts as a transcriptional repressor when it is tethered to Gal4 DNA-binding domain. The repressive activity requires a trichostatin A–sensitive histone deacetylase (HDAC) activity, and SC1 is found in a complex with HDACs 1, 2, and 3. Transcriptional repression exerted by SC1 requires the presence of its zinc finger domains and the PR domain. Additionally, these two domains are involved in the efficient block of BrdU incorporation by SC1. The zinc finger domains are also necessary to direct SC1's nuclear localization. Lastly, SC1 represses the promoter of a promitotic gene, cyclin E, suggesting a mechanism for how growth arrest is regulated by SC1

    Organic matter processing on dry riverbeds is more reactive to water diversion and pollution than on wet channels

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    Rivers are severely affected by human activities and many are simultaneously impacted by multiple stressors. Water diversion for hydropower generation affects ecosystem functioning of the bypassed reaches, which can alternate between periods with natural discharge and others with reduced flow that increase the surface of dry riverbeds. In parallel, urban pollution contributes a complex mixture of nutrients, organic matter, heavy metals, pesticides, and drugs, thus becoming an important stressor in rivers. However, there is little information on the interaction between both stressors on ecosystem functioning and, particularly, on organic matter processing, a key process linked to the input of energy to food webs. To assess the impact of water diversion and urban pollution on organic matter processing, we selected four rivers in a pollution gradient with a similar diversion scheme and compared reaches upstream and downstream from the diversion weirs. We measured leaf-litter decomposition and carbon dioxide (CO2) fluxes in both the wet channel and the dry riverbed. Water diversion and pollution in the wet channel did not affect CO2 fluxes but reduced microbial decomposition, whereas in the dry riverbed, their interaction reduced total and microbial decomposition and CO2 fluxes. Thus, both stressors affected organic matter processing stronger in dry riverbeds than in the wet channel. These results show that dry riverbeds must be taken into account to assess and manage the impacts of human activities on river ecosystems
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