Proceso judicial y violencia secundaria en víctimas de abuso sexual

El abuso sexual es uno de los hechos criminales más traumatizantes, que atenta contra la integridad tanto física como psicológica de quien lo sufre, en tanto se ha violentado su intimidad. En el marco de las investigaciones por delitos contra la integridad sexual, la pericia psicológica se ha transformado en la prueba relevante a la hora de aportar al esclarecimiento de los hechos. La mayoría de las veces, una de las primeras medidas de instrucción que se ordena es la evaluación de la víctima, quien generalmente es único testigo del hecho. Dos son los puntos de pericia recurrentes: el primero de ellos, determinar la “credibilidad del testimonio”, con el objetivo de validar la denuncia y continuar con la investigación. El segundo, establecer el “impacto del daño”, para determinar la tipología del delito y la pena correspondiente. El sometimiento a los sucesivos actos jurídicos, posteriores a la denuncia, operan sobre la subjetividad vulnerada con efectos “revictimizatorios” (violencia secundaria). Desde un posicionamiento ético, nos vemos frente al desafío de evitar que nuestra intervención constituya un procedimiento invasivo, resguardando el posible impacto que pueda sumarse al daño ya sufrido, a la par de responder al requerimiento efectuado por la autoridad judicial.The sexual abuse is one of the most traumatizing criminal facts, which attack the physical and psychological integrity of the victim, as the privacy has been violated. Within the investigations of the sexual integrity crimes, the expert´s report has been turned relevant proof at the time of bringing enlightenment to the facts. Most of the time, one of the first facts that require the investigation, is the victim´s evaluation, who generally is the only witness of the scene. Two skill points are the most required, the first of them is: to determine the credibility of the testimony, in order to validate the complaint and continue with the investigation. The second point is: to establish “the impact of the damage”, to determine the typology of the crime and the corresponding penalty. The submission to the successive legal acts, after the complaint, operates on the violated subjectivity, with re-victimizing effects (secondary violence). From an ethical positioning, we are faced with the challenge of avoiding the fact that our intervention constitutes an invasive procedure, safeguarding the possible impact tan can be added to the damage already suffered, at the same time as responding to the request made by the judicial authority.Facultad de Psicologí

Proceso judicial y violencia secundaria en víctimas de abuso sexual

El abuso sexual es uno de los hechos criminales más traumatizantes, que atenta contra la integridad tanto física como psicológica de quien lo sufre, en tanto se ha violentado su intimidad. En el marco de las investigaciones por delitos contra la integridad sexual, la pericia psicológica se ha transformado en la prueba relevante a la hora de aportar al esclarecimiento de los hechos. La mayoría de las veces, una de las primeras medidas de instrucción que se ordena es la evaluación de la víctima, quien generalmente es único testigo del hecho. Dos son los puntos de pericia recurrentes: el primero de ellos, determinar la “credibilidad del testimonio”, con el objetivo de validar la denuncia y continuar con la investigación. El segundo, establecer el “impacto del daño”, para determinar la tipología del delito y la pena correspondiente. El sometimiento a los sucesivos actos jurídicos, posteriores a la denuncia, operan sobre la subjetividad vulnerada con efectos “revictimizatorios” (violencia secundaria). Desde un posicionamiento ético, nos vemos frente al desafío de evitar que nuestra intervención constituya un procedimiento invasivo, resguardando el posible impacto que pueda sumarse al daño ya sufrido, a la par de responder al requerimiento efectuado por la autoridad judicial.The sexual abuse is one of the most traumatizing criminal facts, which attack the physical and psychological integrity of the victim, as the privacy has been violated. Within the investigations of the sexual integrity crimes, the expert´s report has been turned relevant proof at the time of bringing enlightenment to the facts. Most of the time, one of the first facts that require the investigation, is the victim´s evaluation, who generally is the only witness of the scene. Two skill points are the most required, the first of them is: to determine the credibility of the testimony, in order to validate the complaint and continue with the investigation. The second point is: to establish “the impact of the damage”, to determine the typology of the crime and the corresponding penalty. The submission to the successive legal acts, after the complaint, operates on the violated subjectivity, with re-victimizing effects (secondary violence). From an ethical positioning, we are faced with the challenge of avoiding the fact that our intervention constitutes an invasive procedure, safeguarding the possible impact tan can be added to the damage already suffered, at the same time as responding to the request made by the judicial authority.Facultad de Psicologí

Proceso judicial y violencia secundaria en víctimas de abuso sexual

El abuso sexual es uno de los hechos criminales más traumatizantes, que atenta contra la integridad tanto física como psicológica de quien lo sufre, en tanto se ha violentado su intimidad. En el marco de las investigaciones por delitos contra la integridad sexual, la pericia psicológica se ha transformado en la prueba relevante a la hora de aportar al esclarecimiento de los hechos. La mayoría de las veces, una de las primeras medidas de instrucción que se ordena es la evaluación de la víctima, quien generalmente es único testigo del hecho. Dos son los puntos de pericia recurrentes: el primero de ellos, determinar la “credibilidad del testimonio”, con el objetivo de validar la denuncia y continuar con la investigación. El segundo, establecer el “impacto del daño”, para determinar la tipología del delito y la pena correspondiente. El sometimiento a los sucesivos actos jurídicos, posteriores a la denuncia, operan sobre la subjetividad vulnerada con efectos “revictimizatorios” (violencia secundaria). Desde un posicionamiento ético, nos vemos frente al desafío de evitar que nuestra intervención constituya un procedimiento invasivo, resguardando el posible impacto que pueda sumarse al daño ya sufrido, a la par de responder al requerimiento efectuado por la autoridad judicial.The sexual abuse is one of the most traumatizing criminal facts, which attack the physical and psychological integrity of the victim, as the privacy has been violated. Within the investigations of the sexual integrity crimes, the expert´s report has been turned relevant proof at the time of bringing enlightenment to the facts. Most of the time, one of the first facts that require the investigation, is the victim´s evaluation, who generally is the only witness of the scene. Two skill points are the most required, the first of them is: to determine the credibility of the testimony, in order to validate the complaint and continue with the investigation. The second point is: to establish “the impact of the damage”, to determine the typology of the crime and the corresponding penalty. The submission to the successive legal acts, after the complaint, operates on the violated subjectivity, with re-victimizing effects (secondary violence). From an ethical positioning, we are faced with the challenge of avoiding the fact that our intervention constitutes an invasive procedure, safeguarding the possible impact tan can be added to the damage already suffered, at the same time as responding to the request made by the judicial authority.Facultad de Psicologí

Subclinical carotid atherosclerosis predicts all-cause mortality and cardiovascular events in obese patients with negative exercise echocardiography

BACKGROUND: Obesity is a major health problem due to its high prevalence. The relationship between obesity and cardiovascular disease is unclear. Some studies agree that certain conditions associated with obesity, such as physical inactivity or cardiovascular risk factors, are responsible for cardiovascular risk excess among obese people. Carotid intima-media thickness and carotid plaques (CP) have been associated with cardiovascular adverse events in healthy populations, and recent data suggest a higher prevalence of subclinical carotid atherosclerosis in obese and metabolically unhealthy patients. However, there are no studies correlating subclinical atherosclerosis and adverse events (AE) in obese subjects. AIM: To determine the association between carotid disease and AE in obese patients with negative exercise echocardiography (EE). METHODS: From January 1, 2006 to December 31, 2010, 2000 consecutive patients with a suspicion of coronary artery disease were submitted for EE and carotid ultrasonography. Exclusion criteria included previous vascular disease, left ventricular ejection fraction < 50%, positive EE, significant valvular heart disease and inferior to submaximal EE. An AE was defined as all-cause mortality, myocardial infarction and cerebrovascular accident. Subclinical atherosclerosis was defined as CP presence according to Manheim and the American Society of Echocardiography Consensus. RESULTS: Of the 652 patients who fulfilled the inclusion criteria, 226 (34.7%) had body mass indexes ≥ 30 kg/m2, and 76 of them (33.6%) had CP. During a mean follow-up time of 8.2 (2.1) years, 27 AE were found (11.9%). Mean event-free survival at 1, 5 and 10 years was 99.1% (0.6), 95.1% (1.4) and 86.5% (2.7), respectively. In univariate analysis, CP predicted AE [hazard ratio (HR) 2.52, 95% confidence interval (CI) 1.17-5.46; P = 0.019]. In multivariable analysis, the presence of CP remained a predictor of AE (HR 2.26, 95%CI 1.04-4.95, P = 0.041). Other predictors identified were glomerular filtration rate (HR 0.98, 95%CI 0.96-0.99; P = 0.023), peak metabolic equivalents (HR 0.83, 95%CI 0.70-0.99, P = 0.034) and moderate mitral regurgitation (HR 5.02, 95%CI 1.42-17.75, P = 0.012). CONCLUSION: Subclinical atherosclerosis defined by CP predicts AE in obese patients with negative EE. These patients could benefit from aggressive prevention measures

Desarrollo de competencias a través de la generación y desarrollo de una idea empresarial

[EN] This paper aims to describe the conditions and learning outcomes of a teaching and learning activity in the degree BSc in Engineering and Management in the university center EDEM – Business School. All students enrolled in this degree during 2017/18 participated in this initiative. The activity was presented as a multidisciplinary competition based in the generation and development of business ideas. Agile Project management methodologies and Lean Canvas techniques were applied in this activity. Once the competition finished, students scored how the activity had contributed to the development of generic competencies inherent to the degree. Our findings show that the activity provided an adequate learning environment for the application of knowledge, decisión – making, teamwork and oral communication. These results represent a valuable experience for students, as well as for the university center ans professors. Meanwhile, this activity can be applied to other degrees including cross – sectional projects in the study plans.[ES] El presente trabajo describe el planteamiento y resultados de una actividad de enseñanza – aprendizaje en el título Grado en Ingeniería en Gestión Empresarial del centro univeresitario EDEM – Escuela de empresarios. Todos los estudiantes matriculados en el título durante el curso 2017/18 participaron en esta iniciativa. La actividad se planteó como una competición multidisciplinar de generación y desarrollo de ideas de negocio. En esta actividad se aplicaron metodologías ágiles de proyectos y técnicas de Lean Canvas. Tras finalizar la competición, los estudiantes valoraron cuantitativamente cómo la actividad había contribuído a adquirir cada una de las competencias genéricas del título. Los resultados muestran que la actividad resultó un entorno de trabajo ideal para aplicar conocimientos, tomar decisiones, trabajar en equipo y comunicación oral. Los aprendizajes adquiridos en este actividad supone una valiosa experiencia para los estudiantes, pero también para el centro y los profesores implicados en su organización. Del mismo modo, es susceptible de adaptación en otros grados de futura implantación, que incluyen proyectos transversales a nivel curricular en sus planes académicos.Conchado Peiró, A.; Pérez Lacasa, V.; Fernández Aguilar, E.; Egea Ronda, L. (2018). Desarrollo de competencias a través de la generación y desarrollo de una idea empresarial. En IN-RED 2018. IV Congreso Nacional de Innovación Educativa y Docencia en Red. Editorial Universitat Politècnica de València. 1320-1329. https://doi.org/10.4995/INRED2018.2018.8854OCS1320132

La identidad del becarie UNLP: prácticas y trayectos en investigación, docencia, extensión y transferencia

El taller fue propuesto y coordinado por les investigadores del Programa de Retención de Doctores Nadia Ledesma Prietto, María Andrea Farina, Virginia Cáneva, Joaquín Blas Perez y Maria Fernanda Rossi Batiz. El mismo se planteó como un espacio participativo de discusión de las funciones de investigación, docencia, extensión y transferencia en el marco de las tareas concretas de les becaries en la UNLP. La actividad tuvo una dinámica de taller para propiciar el diálogo entre les becaries que destacaron el valor de la propuesta participando activamente. Hubo cuarenta y dos asistentes: becaries doctorales y posdoctorales, ex-becaries y estudiantes candidatos a becaries de investigación de distintas unidades académicas de nuestra casa de altos estudios. Entre los participantes hubo bióloges, comunicadores, abogades, diseñadores, docentes de nivel universitario que ejercen en niveles medio y terciario, extensionistas, músicxs, licenciades en turismo, agrónomes, químicxs entre otros. La identidad del becarie se expresa en esta actitud participativa y reflexiva sobre las formas en las que se integran las distintas funciones académicas.Universidad Nacional de La Plat

Bimetallic NiFe nanoparticles supported on CeO2 as catalysts for methane steam reforming

Ni-Fe nanocatalysts supported on CeO2 have been prepared for the catalysis of methane steam reforming (MSR) aiming for coke-resistant noble metal-free catalysts. The catalysts have been synthesized by traditional incipient wetness impregnation as well as dry ball milling, a green and more sustainable preparation method. The impact of the synthesis method on the catalytic performance and the catalysts’ nanostructure has been investigated. The influence of Fe addition has been addressed as well. The reducibility and the electronic and crystalline structure of Ni and Ni-Fe mono- and bimetallic catalysts have been characterized by temperature programmed reduction (H2-TPR), in situ synchrotron X-ray diffraction (SXRD), X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. Their catalytic activity was tested between 700 and 950 °C at 108 L gcat-1 h-1 and with the reactant flow varying between 54 and 415 L gcat-1 h-1 at 700 °C. Hydrogen production rates of 67 mol gmet-1 h-1 have been achieved. The performance of the ball-milled Fe0.1Ni0.9/CeO2 catalyst was similar to that of Ni/CeO2 at high temperatures, but Raman spectroscopy revealed a higher amount of highly defective carbon on the surface of Ni-Fe nanocatalysts. The reorganization of the surface under MSR of the ball-milled NiFe/CeO2 has been monitored by in situ near-ambient pressure XPS experiments, where a strong reorganization of the Ni-Fe nanoparticles with segregation of Fe toward the surface has been observed. Despite the catalytic activity being lower in the low-temperature regime, Fe addition for the milled nanocatalyst increased the coke resistance and could be an efficient alternative to industrial Ni/Al2O3 catalysts.Peer ReviewedPostprint (published version

Determinants of Progression and Regression of Subclinical Atherosclerosis Over 6 Years.

BACKGROUND Atherosclerosis is a systemic disease that frequently begins early in life. However, knowledge about the temporal disease dynamics (ie, progression or regression) of human subclinical atherosclerosis and their determinants is scarce. OBJECTIVES This study sought to investigate early subclinical atherosclerosis disease dynamics within a cohort of middle-aged, asymptomatic individuals by using multiterritorial 3-dimensional vascular ultrasound (3DVUS) imaging. METHODS A total of 3,471 participants from the PESA (Progression of Early Subclinical Atherosclerosis) cohort study (baseline age 40-55 years; 36% female) underwent 3 serial 3DVUS imaging assessments of peripheral arteries at 3-year intervals. Subclinical atherosclerosis was quantified as global plaque volume (mm3) (bilateral carotid and femoral plaque burden). Multivariable logistic regression models for progression and regression were developed using stepwise forward variable selection. RESULTS Baseline to 6-year subclinical atherosclerosis progression occurred in 32.7% of the cohort (17.5% presenting with incident disease and 15.2% progressing from prevalent disease at enrollment). Regression was observed in 8.0% of those patients with baseline disease. The effects of higher low-density lipoprotein cholesterol (LDL-C) and elevated systolic blood pressure (SBP) on 6-year subclinical atherosclerosis progression risk were more pronounced among participants in the youngest age stratum (Pinteraction = 0.04 and 0.02, respectively). CONCLUSIONS Over 6 years, subclinical atherosclerosis progressed in one-third of middle-age asymptomatic subjects. Atherosclerosis regression is possible in early stages of the disease. The impact of LDL-C and SBP on subclinical atherosclerosis progression was more pronounced in younger participants, a finding suggesting that the prevention of atherosclerosis and its progression could be enhanced by tighter risk factor control at younger ages, with a likely long-term impact on reducing the risk of clinical events. (Progression of Early Subclinical Atherosclerosis [PESA; also PESA-CNIC-Santander]; NCT01410318).S

Multidisciplinary Prehabilitation and Postoperative Rehabilitation for Avoiding Complications in Patients Undergoing Resection of Colon Cancer: Rationale, Design, and Methodology of the ONCOFIT Study

ONCOFIT is a randomized clinical trial with a two-arm parallel design aimed at determining the influence of a multidisciplinary Prehabilitation and Postoperative Program (PPP) on post-surgery complications in patients undergoing resection of colon cancer. This intervention will include supervised physical exercise, dietary behavior change, and psychological support comparing its influence to the standard care. Primary and secondary endpoints will be assessed at baseline, at preoperative conditions, at the end of the PPP intervention (after 12 weeks) and 1-year post-surgery, and will include: post-surgery complications (primary endpoint); prolonged hospital length of stay; readmissions and emergency department call within 1-year after surgery; functional capacity; patient reported outcome measures targeted; anthropometry and body composition; clinical/tumor parameters; physical activity levels and sedentariness; dietary habits; other unhealthy habits; sleep quality; and fecal microbiota diversity and composition. Considering the feasibility of the present intervention in a real-life scenario, ONCOFIT will contribute to the standardization of a cost-effective strategy for preventing and improving health-related consequences in patients undergoing resection of colon cancer with an important clinical and economic impact, not only in the scientific community, but also in clinical practice.This study was funded by the University of Granada, Plan Propio de Investigación 2016-Excellence actions: Unit of Excellence on Exercise and Health (UCEES). P.C. was supported by the Margarita Salas postdoctoral grant, convened by de University of the Basque Country (UPV/EHU), funded by the Ministry of Universities of Spain and the European Union-Next Generation EU

Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth

The cellular transformation of normal functional cells to neoplastic ones implies alterations in the cellular metabolism and mitochondrial function in order to provide the bioenergetics and growth requirements for tumour growth progression. Currently, the mitochondrial physiology and dynamic shift during pituitary tumour development are not well understood. Pituitary tumours present endocrine neoplastic benign growth which, in previous reports, we had shown that in addition to increased proliferation, these tumours were also characterized by cellular senescence signs with no indication of apoptosis. Here, we show clear evidence of oxidative stress in pituitary cells, accompanied by bigger and round mitochondria during tumour development, associated with augmented biogenesis and an increased fusion process. An activation of the Nrf2 stress response pathway together with the attenuation of the oxidative damage signs occurring during tumour development were also observed which will probably provide survival advantages to the pituitary cells. These neoplasms also presented a progressive increase in lactate production, suggesting a metabolic shift towards glycolysis metabolism. These findings might imply an oxidative stress state that could impact on the pathogenesis of pituitary tumours. These data may also reflect that pituitary cells can modulate their metabolism to adapt to different energy requirements and signalling events in a pathophysiological situation to obtain protection from damage and enhance their survival chances. Thus, we suggest that mitochondria function, oxidative stress or damage might play a critical role in pituitary tumour progression.Fil: Sabatino, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Grondona, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Sosa, Liliana del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Mongi Bragato, Bethania del Carmen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Carreño, Lucía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Juarez, Andrea Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: da Silva, Rodrigo A.. Universidad Federal de Santa Catarina, Brasil; BrasilFil: Remor, Aline. Universidad Federal de Santa Catarina, Brasil; BrasilFil: de Bortoli, Lucila. Universidad Federal de Santa Catarina, Brasil; BrasilFil: Paula Martins, Roberta de. Universidad Federal de Santa Catarina, Brasil; BrasilFil: Pérez, Pablo Aníbal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Centro de Microscopía Electrónica; ArgentinaFil: Petiti, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Centro de Microscopía Electrónica; ArgentinaFil: Gutiérrez, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Centro de Microscopía Electrónica; ArgentinaFil: Torres, Alicia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Centro de Microscopía Electrónica; ArgentinaFil: Latini, Alexandra. Universidad Federal de Santa Catarina, Brasil; BrasilFil: de Paul, Ana Lucia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Centro de Microscopía Electrónica; Argentin