The Effect of Thermal Coefficients on Temperature Condition of the Blank in FE Analysis of Warm Hydro mechanical Deep Drawing Process

A challenge to conduct the most accurate FE simulations in Warm Hydromechanical Deep Drawing (WHDD) process is to predict temperature condition of the blank which was held between the heated dies and cooled punch. This is possible by knowing effects of thermal coefficients in the FE analysis of WHDD process and modeling of the heat transfer between the blank and tools accurately. In this study effects of thermal coefficients on the temperature condition of the blank in the FE analysis of WHDD to conduct accurate FE simulations of the process. So, it can be possible to predict deformation behavior of the materials accurately and determining the proper forming conditions in less time and shorting development time.&nbsp

Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings

Aim: This study aims to assess of using asetylsalicyclic acid (ASA) on non-fatal major and minor bleeding events in patients with inappropriate, primary and secondary prevention groups

Comparison of choroidal thickness in patients with active and stable thyroid eye disease

ABSTRACT Purpose: To compare the choroidal thickness in active and stable phases of thyroid eye disease. Methods: Forty-seven eyes of 47 patients with thyroid eye disease were prospectively studied. Patients were evaluated on the basis of their clinical activity scores, with scores 33 defined as active disease. Subfoveal, temporal macular, nasal macular, temporal peripapillary, and nasal peripapillary choroidal thickness measurements were performed with Cirrus enhanced depth imaging spectral-domain optical coherence tomography, and the results in the two groups were compared. Results: Twenty-four patients were int he active group, whereas 23 patients were in the stable group. Choroidal thickness was significantly higher in the subfoveal and temporal macular regions in the active group. Although the nasal macular and peripapillary values were also higher in the active group, the difference was insignificant. Conclusions: Subfoveal choroidal thickness was significantly higher in patients with thyroid eye disease in the active phase than in those with stable phase disease

Blood pressure response is impaired in patients with exercise-induced ventricular ectopy

Exercise-induced ventricular ectopy (EIVE) has clinical and prognostic significance. But the mechanism underlying EWE-related mortality still remains unclear. This study aims to assess blood pressure alteration in patients with EIVE and to identify the potential causes of increased mortality in this patient group. A total number of 3611 patients were screened within a 1-year period, and patients with a structural heart disease, coronary artery disease, hypertension, diabetes mellitus, thyroid dysfunction, and chronic renal disease were excluded from the study. A total number of 98 patients with no chronic disease, who were retrospectively diagnosed with EIVE, were included in the study as patient group and 116 patients without EWE were included as control group. The median age, gender distribution, laboratory test results, and echocardiographic findings were similar between the two groups. Systolic blood pressure (SBP) alterations during exercise stress testing were found to be significantly different (P < .001). Moreover, EWE group had significantly higher peak SBP (P < .001). A significant positive relation was found between peak SBP level and ventricular ectopy count (r:0.27, P = .006). Our study showed that EIVE patients without a structural heart disease or a chronic disease had higher peak SBP levels. Higher SBP alteration can be related to ventricular ectopy occurrence during exercise stress testing, which can be a possible reason underlying the increased rate of mortality among EWE patients. (C) 2016 American Society of Hypertension. All rights reserved

The Effect of MMP-1 on Wound Healing and Scar Formation

Background In this study, we investigated the effect of matrix metalloproteinase-1 (MMP-1) on wound healing on skin in a model produced in rats

Diagnosis and treatment of carotid body tumors

ABSTRACT Objective: Carotid body tumors (CBTs), especially familial paragangliomas, are rare benign neoplasm, accounting for &lt;0.5% of all tumors; and they are the most common extra-adrenal paraganglioma. Because of peripheral vascular and neural invasion or compression of tumors, early diagnosis and treatments are very important, whereas this kind of tumors have got slow progression and low malignity potential. The aim of this study was to review an institutional experience in the management of paragangliomas. Methodology: In this study, CBTs were clinically suspected in 33 patients but diagnosed by histopathology in between 1999 and 2011 at our department. Three of these patients presented with bilateral tumors. All but one was operated upon. The ages of the 48.3 surgically treated patients ranged 32-58 years. A mass in the neck was the common symptom in all patients. The patients were classified according to the Shamblin classification. There were 17 patients (11 women 6 men) in the first group, 13 patients (9 women, 4 men) in the second group, and 3 patients (2 women 1 man) in the third group. Results: All of these 33 surgically treated patients had confirmed CBT by histopathology. CBTs were resected without a shunt procedure. No mortality occurred, however one patient experienced Horner syndrome post operatively. In the follow up period, no recurrences were observed. Three of the patients was had hoarseness, but improved after six months. No stroke occurred in the patients. Conclusion: CBTs are infrequent neoplasm; their surgical treatment is highly dependent on the ability and experience of the surgeon. The diagnostic and therapeutic relevance reside in making a timely diagnosis to propose a surgical treatment aimed at preventing complications and neurological damage. Surgical resection is usually definitive therapy for these lesions

Adaptive neuro-fuzzy computing technique for suspended sediment estimation

This paper investigates the accuracy of an adaptive neuro-fuzzy computing technique in suspended sediment estimation. The monthly streamflow and suspended sediment data from two stations, Kuylus and Salur Koprusu, in Kizilirmak Basin in Turkey are used as case studies. The estimation results obtained by using the neuro-fuzzy technique are tested and compared with those of the artificial neural networks and sediment rating curves. Root mean squared errors, mean absolute errors and correlation coefficient statistics are used as comparing criteria for the evaluation of the models' performances. The comparison results reveal that the neuro-fuzzy models can be employed successfully in monthly suspended sediment estimation. (C) 2008 Elsevier Ltd. All rights reserved