1,146 research outputs found

    Spin-dependent transport in p+-CdBxF2-x - n-CdF2 planar structures

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    The CV measurements and tunneling spectroscopy are used to study the ballistic transport of the spin-polarized holes by varying the value of the Rashba spin-orbit interaction (SOI) in the p-type quantum well prepared on the surface of the n-CdF2 bulk crystal. The findings of the hole conductance oscillations in the plane of the p-type quantum well that are due to the variations of the Rashba SOI are shown to be evidence of the spin transistor effect, with the amplitude of the oscillations close to e2/h.Comment: 5 pages, 6 figure

    Compared effects of inhibition and exogenous administration of hydrogen sulphide in ischaemia-reperfusion injury

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    INTRODUCTION: Haemorrhagic shock is associated with an inflammatory response consecutive to ischaemia-reperfusion (I/R) that leads to cardiovascular failure and organ injury. The role of and the timing of administration of hydrogen sulphide (H2S) remain uncertain. Vascular effects of H2S are mainly mediated through K+ATP-channel activation. Herein, we compared the effects of D,L-propargylglycine (PAG), an inhibitor of H2S production, as well as sodium hydrosulphide (NaHS), an H2S donor, on haemodynamics, vascular reactivity and cellular pathways in a rat model of I/R. We also compared the haemodynamic effects of NaHS administered before and 10 minutes after reperfusion. METHODS: Mechanically ventilated and instrumented rats were bled during 60 minutes in order to maintain mean arterial pressure at 40 +/- 2 mmHg. Ten minutes prior to retransfusion, rats randomly received either an intravenous bolus of NaHS (0.2 mg/kg) or vehicle (0.9% NaCl) or PAG (50 mg/kg). PNU, a pore-forming receptor inhibitor of K+ATP channels, was used to assess the role of K+ATP channels. RESULTS: Shock and I/R induced a decrease in mean arterial pressure, lactic acidosis and ex vivo vascular hyporeactivity, which were attenuated by NaHS administered before reperfusion and PNU but not by PAG and NaHS administered 10 minutes after reperfusion. NaHS also prevented aortic inducible nitric oxide synthase expression and nitric oxide production while increasing Akt and endothelial nitric oxide synthase phosphorylation. NaHS reduced JNK activity and p-P38/P38 activation, suggesting a decrease in endothelial cell activation without variation in ERK phosphorylation. PNU + NaHS increased mean arterial pressure when compared with NaHS or PNU alone, suggesting a dual effect of NaHS on vascular reactivity. CONCLUSION: NaHS when given before reperfusion protects against the effects of haemorrhage-induced I/R by acting primarily through a decrease in both proinflammatory cytokines and inducible nitric oxide synthase expression and an upregulation of the Akt/endothelial nitric oxide synthase pathway

    Review of low-cost sensors for indoor air quality: Features and applications

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    Humans spend the majority of their time indoors, where they are potentially exposed to hazardous pollutants. Within this context, over the past few years, there has been an upsurge of low-cost sensors (LCS) for the measurement of indoor air pollutants, motivated both by recent technological advances and by increased awareness of indoor air quality (IAQ) and its potential negative health impacts. Although not meeting the performance requirements for reference regulatory-equivalent monitoring indoors, LCS can provide informative measurements, offering an opportunity for high-resolution monitoring, emission source identification, exposure mitigation and managing IAQ and energy efficiency, among others. This article discusses the strengths and limitations that LCS offer for applications in the field of IAQ monitoring; it provides an overview of existing sensor technologies and gives recommendations for different indoor applications, considering their performance in the complex indoor environment and discussing future trends

    Stability and power optimality in time-periodic flapping wing structures

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    This paper investigates the nonlinear dynamics of a vehicle with two flexible flapping wings. The body dynamics and the wings\u27 deformation are monolithically grouped into a single system of equations, with aerodynamics accounted for by a quasi-steady blade element method. A periodic shooting method is then used to locate closed orbits of this non-autonomous system, and Floquet multipliers assess the linearized stability about the nonlinear orbit. This framework is then exposed to a gradient based optimizer, in order to quantify the role of wing planform variables, wing structure variables, and kinematic actuation variables in obtaining vehicles with superior open-loop stability characteristics, and/or low-power requirements

    Cadmium accumulation and interactions with zinc, copper, and manganese, analysed by ICP-MS in a long-term Caco-2 TC7 cell model

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    The influence of long-term exposure to cadmium (Cd) on essential minerals was investigated using a Caco-2 TC7 cells and a multi-analytical tool: microwave digestion and inductively coupled plasma mass spectrometry. Intracellular levels, effects on cadmium accumulation, distribution, and reference concentration ranges of the following elements were determined: Na, Mg, Ca, Cr, Fe, Mn, Co, Ni, Cu, Zn, Mo, and Cd. Results showed that Caco-2 TC7 cells incubated long-term with cadmium concentrations ranging from 0 to 10 lmol Cd/l for 5 weeks exhibited a significant increase in cadmium accumulation. Furthermore, this accumulation was more marked in cells exposed long-term to cadmium compared with controls, and that this exposure resulted in a significant accumulation of copper and zinc but not of the other elements measured. Interactions of Cd with three elements: zinc, copper, and manganese were particularly studied. Exposed to 30 lmol/l of the element, manganese showed the highest inhibition and copper the lowest on cadmium intracellular accumulation but Zn, Cu, and Mn behave differently in terms of their mutual competition with Cd. Indeed, increasing cadmium in the culture medium resulted in a gradual and significant increase in the accumulation of zinc. There was a significant decrease in manganese from 5 lmol Cd/l exposure, and no variation was observed with copper. Abbreviation: AAS – Atomic absorption spectrometry; CRM– Certified reference material; PBS – Phosphate buffered saline without calcium and magnesium; DMEM – Dubelcco’s modified Eagle’s medium

    Structure of the mirror nuclei 9^9Be and 9^9B in a microscopic cluster model

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    The structure of the mirror nuclei 9^9Be and 9^9B is studied in a microscopic α+α+n\alpha+ \alpha+ n and α+α+p\alpha+ \alpha+ p three-cluster model using a fully antisymmetrized 9-nucleon wave function. The two-nucleon interaction includes central and spin-orbit components and the Coulomb potential. The ground state of 9^9Be is obtained accurately with the stochastic variational method, while several particle-unbound states of both 9^9Be and 9^9B are investigated with the complex scaling method.The calculation for 9^9Be supports the recent identification for the existence of two broad states around 6.5 MeV, and predicts the 322−\frac{3}{2}^{-}_2 and 522−\frac{5}{2}^{-}_2 states at about 4.5 MeV and 8 MeV, respectively. The similarity of the calculated spectra of 9^9Be and 9^9B enables one to identify unknown spins and parities of the 9^9B states. Available data on electromagnetic moments and elastic electron scatterings are reproduced very well. The enhancement of the EE1 transition of the first excited state in 9^9Be is well accounted for. The calculated density of 9^9Be is found to reproduce the reaction cross section on a Carbon target. The analysis of the beta decay of 9^9Li to 9^9Be clearly shows that the wave function of 9^9Be must contain a small component that cannot be described by the simple α+α+n\alpha+ \alpha+ n model. This small component can be well accounted for by extending a configuration space to include the distortion of the α\alpha-particle to t+pt+p and h+nh+n partitions.Comment: 24 page

    Incorporating lessons from high-input research into a low-margin year

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    Increased soybean commodity prices in recent years have generated interest in developing high-input systems to increase yield. However, little information exists about the effects of input-intensive, high-yield management on soybean yield and profitability, as well as interactions with basic agronomic practices

    Local search for the surgery admission planning problem

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    We present a model for the surgery admission planning problem, and a meta-heuristic algorithm for solving it. The problem involves assigning operating rooms and dates to a set of elective surgeries, as well as scheduling the surgeries of each day and room. Simultaneously, a schedule is created for each surgeon to avoid double bookings. The presented algorithm uses simple Relocate and Two-Exchange neighbourhoods, governed by an iterated local search framework. The problem's search space associated with these move operators is analysed for three typical fitness surfaces, representing different compromises between patient waiting time, surgeon overtime, and waiting time for children in the morning on the day of surgery. The analysis shows that for the same problem instances, the different objectives give fitness surfaces with quite different characteristics. We present computational results for a set of benchmarks that are based on the admission planning problem in a chosen Norwegian hospital
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