4,120 research outputs found
Coordination of development approval processes revisited â Lagoon Bay Lifestyle Estate (Pty) Ltd v The Minister of Local Government, Environmental Affairs & Development Planning of the Western Cape and Others [2011] 4 All SA 270 (WCC)
From text: This article deals with the decision-making powers of different spheres of government, in terms of various pieces of legislation, with regard to the development of agricultural land and, more specifically, the subdivision or rezoning of such land
Wary Holdings (Pty) Ltd v Stalwo (Pty) Ltd & Another (Trustees of the Hoogekraal Highlands Trust & SAFAMCO Enterprises (Pty) Ltd (amicus curiae); Minister of Agriculture & Land Affairs (intervening)) [2008] JOL 22099 (CC)
In terms of the Subdivision of Agricultural Land Act 70 of 1970, the (national) Minister of Agriculture, Forestry and Fisheries has to authorise, in writing, every application for the subdivision of agricultural land. The following proviso was added to the definition of âagricultural landâ in the Act in 1995: âProvided that land situated in the area of jurisdiction of a transitional council as defined in section 1 of the Local Government Transition Act, 1993 (Act No. 209 of 1993), which immediately prior to the first election of the members of such transitional council was classified as agricultural land, shall remain classified as such.â The question that arose in this case was whether the proviso only existed during the lifetime of transitional councils. An affirmative answer to the above question would result in the de facto and de jure implicit termination (and disappearance) of agricultural land as a category in South African law and, consequently, of the Ministerâs power to approve any subdivision of agricultural land. A negative answer would imply that agricultural land remains as a category, that the provisions of SALA need to be complied with, and that the Ministerâs written approval needs to be obtained for each and every application for subdivision of agricultural land. This article contends that the Constitutional Court was correct in finding that the proviso (and the Act) is still applicable today
Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.
Obesity and extracellular matrix (ECM) density are considered independent risk and prognostic factors for breast cancer. Whether they are functionally linked is uncertain. We investigated the hypothesis that obesity enhances local myofibroblast content in mammary adipose tissue and that these stromal changes increase malignant potential by enhancing interstitial ECM stiffness. Indeed, mammary fat of both diet- and genetically induced mouse models of obesity were enriched for myofibroblasts and stiffness-promoting ECM components. These differences were related to varied adipose stromal cell (ASC) characteristics because ASCs isolated from obese mice contained more myofibroblasts and deposited denser and stiffer ECMs relative to ASCs from lean control mice. Accordingly, decellularized matrices from obese ASCs stimulated mechanosignaling and thereby the malignant potential of breast cancer cells. Finally, the clinical relevance and translational potential of our findings were supported by analysis of patient specimens and the observation that caloric restriction in a mouse model reduces myofibroblast content in mammary fat. Collectively, these findings suggest that obesity-induced interstitial fibrosis promotes breast tumorigenesis by altering mammary ECM mechanics with important potential implications for anticancer therapies
Investigating the impact of the molecular charge-exchange rate on detached SOLPS-ITER simulations
Plasma-molecular interactions generate molecular ions which react with the
plasma and contribute to detachment through molecular activated recombination
(MAR), reducing the ion target flux, and molecular activated dissociation
(MAD), both of which create excited atoms. Hydrogenic emission from these atoms
have been detected experimentally in detached TCV, JET and MAST-U deuterium
plasmas. The TCV findings, however, were in disagreement with SOLPS-ITER
simulations for deuterium indicating a molecular ion density () that was
insufficient to lead to significant hydrogenic emission, which was attributed
to underestimates of the molecular charge exchange rate () for deuterium (obtained by rescaling the hydrogen rates by their
isotope mass).
In this work, we have performed new SOLPS-ITER simulations with the default
rate setup and a modified rate setup where ion isotope mass rescaling was
disabled. This increased the content by . By disabling
ion isotope mass rescaling: 1) the total ion sinks are more than doubled due to
the inclusion of MAR; 2) the additional MAR causes the ion target flux to
roll-over during detachment; 3) the total emission in the divertor
increases during deep detachment by roughly a factor four; 4) the neutral atom
density in the divertor is doubled due to MAD, leading to a 50\% increase in
neutral pressure; 5) total hydrogenic power loss is increased by up to 60\% due
to MAD. These differences result in an improved agreement between the
experiment and the simulations in terms of spectroscopic measurements, ion
source/sink inferences and the occurrence of an ion target flux roll-over
Heat transfer between a nano-tip and a surface
We study quasi-ballistic heat transfer through air between a hot
nanometer-scale tip and a sample. The hot tip/surface configuration is widely
used to perform nonintrusive confined heating. Using a Monte-Carlo simulation,
we find that the thermal conductance reaches 0.8 MW.m-2K-1 on the surface under
the tip and show the shape of the heat flux density distribution
(nanometer-scale thermal spot). These results show that a surface can be
efficiently heated locally without contact. The temporal resolution of the heat
transfer is a few tens of picoseconds.Comment: 4 page
Fine sediment reduces vertical migrations of Gammarus pulex (Crustacea: Amphipoda) in response to surface water loss
Surface and subsurface sediments in river ecosystems are recognized as refuges that may promote invertebrate survival during disturbances such as floods and streambed drying. Refuge use is spatiotemporally variable, with environmental factors including substrate composition, in particular the proportion of fine sediment (FS), affecting the ability of organisms to move through interstitial spaces. We conducted a laboratory experiment to examine the effects of FS on the movement of Gammarus pulex Linnaeus (Crustacea: Amphipoda) into subsurface sediments in response to surface water loss. We hypothesized that increasing volumes of FS would impede and ultimately prevent individuals from migrating into the sediments. To test this hypothesis, the proportion of FS (1â2 mm diameter) present within an open gravel matrix (4â16 mm diameter) was varied from 10 to 20% by volume in 2.5% increments. Under control conditions (0% FS), 93% of individuals moved into subsurface sediments as the water level was reduced. The proportion of individuals moving into the subsurface decreased to 74% at 10% FS, and at 20% FS no individuals entered the sediments, supporting our hypothesis. These results demonstrate the importance of reducing FS inputs into river ecosystems and restoring FS-clogged riverbeds, to promote refuge use during increasingly common instream disturbances
Establishing Lagrangian connections between observations within air masses crossing the Atlantic during the International Consortium for Atmospheric Research on Transport and Transformation experiment
The ITCT-Lagrangian-2K4 (Intercontinental Transport and Chemical Transformation) experiment was conceived with an aim to quantify the effects of photochemistry and mixing on the transformation of air masses in the free troposphere away from emissions. To this end, attempts were made to intercept and sample air masses several times during their journey across the North Atlantic using four aircraft based in New Hampshire (USA), Faial (Azores) and Creil (France). This article begins by describing forecasts from two Lagrangian models that were used to direct the aircraft into target air masses. A novel technique then identifies Lagrangian matches between flight segments. Two independent searches are conducted: for Lagrangian model matches and for pairs of whole air samples with matching hydrocarbon fingerprints. The information is filtered further by searching for matching hydrocarbon samples that are linked by matching trajectories. The quality of these "coincident matches'' is assessed using temperature, humidity and tracer observations. The technique pulls out five clear Lagrangian cases covering a variety of situations and these are examined in detail. The matching trajectories and hydrocarbon fingerprints are shown, and the downwind minus upwind differences in tracers are discussed
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