As festas históricas e religiosas de Luziânia/GO atuando no desenvolvimento do potencial turístico da cidade

Dissertação (mestrado)—Universidade de Brasília, Centro de Excelência em Turismo, Mestrado Profissional em Turismo, 2014A preservação dos patrimônios tangíveis e intangíveis é fundamental para que se possa conhecer a história cultural, social e política de um determinado local. A atividade turística vem se destacando ao longo dos anos não apenas como fator de desenvolvimento econômico, mas também como agente no ato de rememorar e na preservação dos patrimônios históricos e culturais de diferentes lugares. Luziânia, por ser uma das cidades mais antigas do planalto central, com 266 anos, carece de estudos acerca do modo como o seu patrimônio histórico-cultural, tangível e intangível, atua e/ou pode atuar no desenvolvimento do potencial turístico do Município. Portanto o objetivo do estudo em tela é avaliar como a cultura e as festas religiosas de Luziânia podem ser importantes na preservação e divulgação dos patrimônios histórico-culturais da cidade, além da influência que estas festas possuem no desenvolvimento do turismo local. ________________________________________________________________________________ ABSTRACTThe preservation of tangible and intangible is crucial to understand the cultural, social and political history, of a specific location. Tourist activity has been highlighted over the years not only as a factor of economic development, but also as a way of remembering and preserving the historical and cultural heritage of different places. Luziânia, as one of the oldest cities in the central plateau, at 266 years would benefit from studies about how their historical-cultural, tangible and intangible, act and / or could act in the development of the potential tourism of the city. Therefore, the purpose of the study is to evaluate the culture and religious traditions of Luziânia, and it may be important in the process of preservation and dissemination of historical and cultural heritage of the city, besides the influence that these traditions have in the development of local tourism

Physiological characterization of a pyrimidine auxotroph exposes link between uracil phosphoribosyltransferase regulation and riboflavin production in Ashbya gossypii

The blockage of the de novo pyrimidine biosynthetic pathway at the orotidine-5-phosphate decarboxylase level was previously demonstrated to affect riboflavin production in the industrial producer fungus Ashbya gossypii. However, the molecular basis for the unusual sensitivity to uracil displayed by the pyrimidine auxotroph A. gossypii Agura3 was unknown. Here, uridine was shown to be the only intermediate of the pyrimidine salvage pathway able to fully restore this mutants growth. Conversely, uracil, which is routinely used to rescue pyrimidine auxotrophs, had a dose-dependent growth-inhibitory effect. Uracil phosphoribosyltransferase (UPRT) is the pyrimidine salvage pathway enzyme responsible for converting uracil to uridine monophosphate in the presence of phosphoribosyl pyrophosphate (PRPP). Characterization of the A. gossypii UPRT, as produced and purified from Escherichia coli, revealed that uracil concentrations above 1mM negatively affected its activity, thus explaining the hypersensitivity of the Agura3 mutant to uracil. Accordingly, overexpression of the AgUPRT encoding-gene in A. gossypii Agura3 led to similar growth on rich medium containing 5mM uracil or uridine. Decreased UPRT activity ultimately favors the preservation of PRPP, which otherwise may be directed to other pathways. In A. gossypii, increased PRPP availability promotes overproduction of riboflavin. Thus, this UPRT modulation mechanism reveals a putative means of saving precursors essential for riboflavin overproduction by this fungus. A similar uracil-mediated regulation mechanism of the UPRT activity is reported only in two protozoan parasites, whose survival depends on the availability of PRPP. Physiological evidence here discussed indicate that it may be extended to other distantly related flavinogenic fungi.This study was supported by the Portuguese Foundation for Science and technology-FCT(strategic funding UID/BIO/04469/2013, Post-Doc grant SFRH/BPD/110640/2015 and PhD grant PD/BD/113812/2015), and European Regional Development Fund under the scope of Compete2020 (POCI-01-0145-FEDER-006684) and Norte2020 Programa Operacional Regional do Norte (BioTecNorte operation NORTE-01-0145-FEDER-000004).info:eu-repo/semantics/publishedVersio

Offsetting the Impact of CO2 Emissions Resulting from the Transport of Maiêutica’s Academic Campus Community

info:eu-repo/semantics/publishedVersio

Debt and political business cycles in portuguese municipalities

Masters Degree in FinanceThe concept of Politicai Business Cycles considers the relationship between politics and economic policies. International and national empirical works have sought to establish which, if any, of two forms of politicai business cycles exist: opportunistic or partisan. The objective of this work is the study of politicai business cycles (PBC) at local government levei through debt based on a set of Poríuguese data. Traditionally, politicai business cycles are observed through budgetary variables, in particular, investment. Expenditure relates with municipal financing mechanisms, one of which is debt. In order to attempt to discover politicai business cycles in the behaviour of debt, we have built an econometric generic model, supported by a set of variables that has been used in recent studies to capture opportunistic cycles. This model was applied to data for the period 1978-2002, covering seven municipal elections in the years 1979, 1982, 1985, 1989, 1993, 1997 and 2001. An ideological variable was included to study its interaction with the dependent variable on a set of fifteen individual municipalities where partisan cycles were analysed. The model was estimated through OLS linear regressions for a set of data which included three leveis: i) the municipalities of Continental Portugal; ii) the Lisbon district, which is composed of 15 municipalities; and iii) those fifteen individual municipalities. We conclude, on the basis of our results, that opportunistic cycles occur in the first two of the three above-mentioned leveis.info:eu-repo/semantics/publishedVersio

Tudo que é sólido desaquenda desmancha na nuvem: a produção musical de artistas trans na era do streaming

This work provides an overview of transvestigenere musicology: musical production by trans artists. Based on a mapping that raised trans artists around the world, this research focuses on the analysis of the processes of interaction and production of meanings generated by musical creationand enjoyment, observing the relationships created amongthe listeners on the platforms of streaming Spotify and Youtube, through analysis of the numbers of hits, likes and dislikes, comments and geopolitical location of each artist and their listeners.Thus, the research aims to understand the intersections amongidol, fan, hater, music, socio-cultural context and how the connection ofthese elements can promote other perspectives about the world we live in.Este trabalho traça um panorama sobre musicologia transvestigenere: produção musical de artistas trans. A partir de um mapeamento que levantou artistas trans em todo o mundo, essa pesquisa se debruça sobre os processos de interação e produção de sentidos gerados pela criação e fruição musical,observando as relações criadas entre os ouvintes nas plataformas de streaming Spotify e Youtube, através da análise dos números de acessos, likes e dislikes, comentários e localização geopolítica de cada artista e de seus ouvintes.Dessa forma,a pesquisa visa compreender as intersecções entre ídolo, fã, hater, música, contexto sociocultural e como a conexão desses elementos pode promover outras perspectivas sobre o mundo em que vivemos

Nada de novo?: o discurso sobre a crise como dimensão da competição partidária

Esta pesquisa pretende compreender potenciais efeitos exercidos pela entrada de um novo assunto na agenda política - a crise - nas dinâmicas de competição partidária, uma vez que esta traduz a dimensão de interação dos sistemas partidários, permitindo, simultaneamente, observar as posições estrategicamente assumidas que cada um dos partidos e os seus efeitos sistémicos. A análise empírica foi orientada para a obtenção de respostas sobre a forma como os partidos parlamentares se apropriaram do novo assunto na agenda. Para tal, a observação segmentou-se da seguinte forma: i) a posições individualmente assumidas pelos partidos parlamentares sobre as causas de crise; ii) as propostas de solução individualmente apresentadas por cada um dos partidos; iii) as relações, de cooperação e de concurso, que consideraram ser as mais adequadas a desenvolver na situação excecional que a crise representa. Verificou-se que a linha principal de clivagem do sistema partidário português se manteve inalterada, ou seja, a disputa do governo entre PS e PSD, não tendo surgido novas linhas de clivagem. O fator exógeno "crise" foi absorvido, de forma individual, por cada um dos partidos do sistema, não introduzindo alterações significativas na sua estratégia de competição. A polarização de posições, mesmo quando ancorada na valoração normativa das medidas, foi suficientemente clara para que se mantivesse a decidability of the offer. Este facto, denota capacidade de adaptação dos partidos ao novo contexto, apesar da excecionalidade do assunto, tendo estes desenvolvido as estratégias de apropriação que consideraram ser as mais adequadas aos seus objetivos Palavras-chave: Partidos políticos; Competição partidária; Issue Ownership; Sistemas partidários.This research aims at understanding the potential effects exerted by the introduction of a new subject in the political agenda - the crisis - over the dynamics of competition of political parties, as this competition embodies the interactional dimension of party systems, allowing simultaneously to observe the strategically assumed positions that of each party and its systemic effects. The empirical analysis was designed to inquire on the way in which the parliamentary parties appropriated the new topic of the agenda. The observation was thus segmented as follows: i) individual positions taken by the parliamentary parties on the causes of crisis; (ii) individually submitted proposals for a solution; (iii) the cooperation and competition relations which they considered to be the most suitable to develop in the exceptional situation of crisis.ii It was verified that the main line of cleavage of the Portuguese party system remained unchanged, that is, the government dispute between PS and PSD, and no new lines of cleavage emerged. The exogenous "crisis" factor was absorbed, individually, by each party of the system, without significant changes in its competition strategy. The polarization of positions, even when anchored in the normative assessment of the measures, was sufficiently clear to maintain the decidability of the offer. This fact denotes the parties' ability to adapt to the new context, despite the exceptionality of the subject, and they have developed the appropriation strategies that they considered to be the most adequate to their objectives

O manejo da dor em pacientes oncológicos: uma revisão bibliográfica

O câncer é uma doença genética considerada a segunda causa de morte no Brasil. A Organização Mundial da Saúde (OMS) destaca que, de cinco milhões de pessoas que foram a óbito devido a esse problema anualmente e aproximadamente quatro milhões morrem sentindo dor. Estima-se que no Brasil, 62% a 90% das vítimas de câncer possuem algum grau álgico. O enfermeiro deve identificar as necessidades dos pacientes e planejar soluções. O objetivo deste trabalho foi apresentar os principais aspectos relacionados ao manejo da dor em pacientes oncológicos. As estratégias para o alívio álgico podem ser não farmacológicas e farmacológicas. Dentre as alternativas de terapia para os episódios álgicos, há a administração de fármacos e a aplicação de Práticas Integrativas e Complementares de Saúde – PICS. Dessa forma, é importante que o enfermeiro seja capacitado e disponha de conhecimento para integrar todas as terapêuticas para o manejo eficaz da dor.https://repositorio.uniceub.br/jspui/retrieve/37082/21373837.pd