269 research outputs found

    Characterization Of Multiscroll Attractors Using Lyapunov Exponents And Lagrangian Coherent Structures.

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    The present work aims to apply a recently proposed method for estimating Lyapunov exponents to characterize-with the aid of the metric entropy and the fractal dimension-the degree of information and the topological structure associated with multiscroll attractors. In particular, the employed methodology offers the possibility of obtaining the whole Lyapunov spectrum directly from the state equations without employing any linearization procedure or time series-based analysis. As a main result, the predictability and the complexity associated with the phase trajectory were quantified as the number of scrolls are progressively increased for a particular piecewise linear model. In general, it is shown here that the trajectory tends to increase its complexity and unpredictability following an exponential behaviour with the addition of scrolls towards to an upper bound limit, except for some degenerated situations where a non-uniform grid of scrolls is attained. Moreover, the approach employed here also provides an easy way for estimating the finite time Lyapunov exponents of the dynamics and, consequently, the Lagrangian coherent structures for the vector field. These structures are particularly important to understand the stretching/folding behaviour underlying the chaotic multiscroll structure and can provide a better insight of phase space partition and exploration as new scrolls are progressively added to the attractor.2302310

    Unsupervised machine learning approaches to the qq-state Potts model

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    In this paper with study phase transitions of the qq-state Potts model, through a number of unsupervised machine learning techniques, namely Principal Component Analysis (PCA), kk-means clustering, Uniform Manifold Approximation and Projection (UMAP), and Topological Data Analysis (TDA). Even though in all cases we are able to retrieve the correct critical temperatures Tc(q)T_c(q), for q=3,4q = 3, 4 and 55, results show that non-linear methods as UMAP and TDA are less dependent on finite size effects, while still being able to distinguish between first and second order phase transitions. This study may be considered as a benchmark for the use of different unsupervised machine learning algorithms in the investigation of phase transitions.Comment: Added computation of critical exponents; exposition improve

    Molecular detection of EGFRvIII-positive cells in the peripheral blood of breast cancer patients

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    The aim of this study is to evaluate epidermal growth factor receptor variant III, EGFRvIII, a cancer specific mutant, as a possible marker for the diagnosis of breast cancer occult systemic disease. EGFRvIII mRNA was identified by an RT-nested PCR with a high sensitivity. In 102 women studied, the mutant was detected in the peripheral blood of 30% of 33 low risk, early stage patients, in 56% of 18 patients selected for neoadjuvant chemotherapy, in 63.6% of 11 patients with disseminated disease and 0% of 40 control women. In low risk, early stage patients, the presence of one or more tumour characteristics predicting recurrence such as the absence of oestrogen receptors and the presence of ERBB2 or histologic grades G2/G3 was significantly associated with EFGRvIII detection (p < 0.05). EGFRvIII mRNA has characteristics to be a useful marker for the diagnosis of occult systemic disease in breast cancer. Follow-up studies will evaluate its clinical value as a decision criterion for systemic therapy.http://www.sciencedirect.com/science/article/B6T68-4KV2RH2-1/1/8d7f06700e09e0cb34c8a3861e1b0ba

    A novel point mutation in a class IV glucose-6-phosphate dehydrogenase variant (G6PD São Paulo) and polymorphic G6PD variants in São Paulo State, Brazil

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    In this study, we used red cell glucose-6-phosphate dehydrogenase (G6PD) activity to screen for G6PD-deficient individuals in 373 unrelated asymptomatic adult men who were working with insecticides (organophosphorus and carbamate) in dengue prevention programs in 27 cities in São Paulo State, Brazil. Twenty-one unrelated male children suspected of having erythroenzymopathy who were attended at hospitals in São Paulo city were also studied. Fifteen of the 373 adults and 12 of the 21 children were G6PD deficient. G6PD gene mutations were investigated in these G6PD-deficient individuals by using PCR-RFLP, PCR-SSCP analysis and DNA sequencing. Twelve G6PD A-202A/376G and two G6PD Seattle844C, as well as a new variant identified as G6PD São Paulo, were detected among adults, and 11 G6PD A-202A/376G and one G6PD Seattle844C were found among children. The novel mutation c.660C > G caused the replacement of isoleucine by methionine (I220M) in a region near the dimer interface of the molecule. The conservative nature of this mutation (substitution of a nonpolar aliphatic amino acid for another one) could explain why there was no corresponding change in the loss of G6PD activity (64.5% of normal activity in both cases)

    Estimates of forest canopy height and aboveground biomass using ICESat

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    Exchange of carbon between forests and the atmosphere is a vital component of the global carbon cycle. Satellite laser altimetry has a unique capability for estimating forest canopy height, which has a direct and increasingly well understood relationship to aboveground carbon storage. While the Geoscience Laser Altimeter System (GLAS) onboard the Ice, Cloud and land Elevation Satellite (ICESat) has collected an unparalleled dataset of lidar waveforms over terrestrial targets, processing of ICESat data to estimate forest height is complicated by the pulse broadening associated with large-footprint, waveform-sampling lidar. We combined ICESat waveforms and ancillary topography from the Shuttle Radar Topography Mission to estimate maximum forest height in three ecosystems; tropical broadleaf forests in Brazil, temperate broadleaf forests in Tennessee, and temperate needleleaf forests in Oregon. Final models for each site explained between 59% and 68% of variance in field-measured forest canopy height (RMSE between 4.85 and 12.66 m). In addition, ICESat-derived heights for the Brazilian plots were correlated with field-estimates of aboveground biomass (r(2) = 73%, RMSE = 58.3 Mgha(-1))

    Size and frequency of natural forest disturbances and Amazon carbon balance

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    Forest inventory studies in the Amazon indicate a large terrestrial carbon sink. However, field plots may fail to represent forest mortality processes at landscape-scales of tropical forests. Here we characterize the frequency distribution of disturbance events in natural forests from 0.01 ha to 2,651 ha size throughout Amazonia using a novel combination of forest inventory, airborne lidar and satellite remote sensing data. We find that small-scale mortality events are responsible for aboveground biomass losses of B1.28 Pg C y 1 over the entire Amazon region. We also find that intermediate-scale disturbances account for losses of B0.01 Pg C y 1 , and that the largest-scale disturbances as a result of blow-downs only account for losses of B0.003 Pg C y 1 . Simulation of growth and mortality indicates that even when all carbon losses from intermediate and large-scale disturbances are considered, these are outweighed by the net biomass accumulation by tree growth, supporting the inference of an Amazon carbon sink

    A new field instrument for leaf volatiles reveals an unexpected vertical profile of isoprenoid emission capacities in a tropical forest.

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    Both plant physiology and atmospheric chemistry are substantially altered by the emission of volatile isoprenoids (VI), such as isoprene and monoterpenes, from plant leaves. Yet, since gaining scientific attention in the 1950?s, empirical research on leaf VI has been largely confined to laboratory experiments and atmospheric observations. Here, we introduce a new field instrument designed to bridge the scales from leaf to atmosphere, by enabling precision VI detection in real time from plants in their natural ecological setting. With a field campaign in the Brazilian Amazon, we reveal an unexpected distribution of leaf emission capacities (EC) across the vertical axis of the forest canopy, with EC peaking in the mid-canopy instead of the sun-exposed canopy surface, and moderately high emissions occurring in understory specialist species. Compared to the simple interpretation that VI protect leaves from heat stress at the hot canopy surface, our results encourage a more nuanced view of the adaptive role of VI in plants. We infer that forest emissions to the atmosphere depend on the dynamic microenvironments imposed by canopy structure, and not simply on canopy surface conditions. We provide a new emissions inventory from 52 tropical tree species, revealing moderate consistency in EC within taxonomic groups. We highlight priorities in leaf volatiles research that require field-portable detection systems. Our self-contained, portable instrument provides real-time detection and live measurement feedback with precision and detection limits better than 0.5 nmolVI m-2 leaf s-1. We call the instrument ?PORCO? based on the gas detection method: photoionization of organic compounds. We provide a thorough validation of PORCO and demonstrate its capacity to detect ecologically driven variation in leaf emission rates and thus accelerate a nascent field of science: the ecology and ecophysiology of plant volatiles

    Carbon Dynamics in a Human-Modified Tropical Forest: A Case Study Using Multi-Temporal LiDAR Data

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    Tropical forests hold significant amounts of carbon and play a critical role on Earth´s climate system. To date, carbon dynamics over tropical forests have been poorly assessed, especially over vast areas of the tropics that have been affected by some type of disturbance (e.g., selective logging, understory fires, and fragmentation). Understanding the multi-temporal dynamics of carbon stocks over human-modified tropical forests (HMTF) is crucial to close the carbon cycle balance in the tropics. Here, we used multi-temporal and high-spatial resolution airborne LiDAR data to quantify rates of carbon dynamics over a large patch of HMTF in eastern Amazon, Brazil. We described a robust approach to monitor changes in aboveground forest carbon stocks between 2012 and 2018. Our results showed that this particular HMTF lost 0.57 m·yr−1 in mean forest canopy height and 1.38 Mg·C·ha−1·yr−1 of forest carbon between 2012 and 2018. LiDAR-based estimates of Aboveground Carbon Density (ACD) showed progressive loss through the years, from 77.9 Mg·C·ha−1 in 2012 to 53.1 Mg·C·ha−1 in 2018, thus a decrease of 31.8%. Rates of carbon stock changes were negative for all time intervals analyzed, yielding average annual carbon loss rates of −1.34 Mg·C·ha−1·yr−1. This suggests that this HMTF is acting more as a source of carbon than a sink, having great negative implications for carbon emission scenarios in tropical forests. Although more studies of forest dynamics in HMTFs are necessary to reduce the current remaining uncertainties in the carbon cycle, our results highlight the persistent effects of carbon losses for the study area. HMTFs are likely to expand across the Amazon in the near future. The resultant carbon source conditions, directly associated with disturbances, may be essential when considering climate projections and carbon accounting methods
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