Improving Nutritional quality of Millet (Pennisetum americanum) by solid state fermentation and the effects on the growth performance of African Cat Fish.

Millet is becoming prominent in fish feed formulation as energy source but there is need to increase its protein level and remove the antinutrient for its maximum utilization to be effected. The objective  of this study to determine the level of improving the nutritive value, removing the antinutrient of millet by solid state fermentation process using Aspergillus niger and effect of the product on the growth performance of African catfish fingerlings. Millet seeds were sterilized for 30 minutes, inoculated with Ammonium sulphate and urea at 10gNKg-1 substrate, spores of Aspergillus niger and sulphuric acid to obtain initial pH of 3.5-40. The mixture was fermented for 84h at 350C and 90-95% RH in the laboratory, then sundried for 48hrs, five diets(40% Crude protein) were formulated, containing 0, 4, 8, 12 and 16% inclusion levels of fermented millet . The diets were fed to 225 fingerlings (two week old) weighing 1.28+0.2, stocked at density of 15 fingerlings per tank in triplicate. Millet protein increased from 10.9% to 17.0%, phytic acid reduced significantly from 0.02mg/100g to 0.014mg/100g. fingerlings fed 4% inclusion has the highest value of Percentage weight gain (PWG) 110.2%, Protein Efficiency Ratio (PER) 1.4 and lowest value of Feed conversion ratio (FCR) 1.8 while fingerlings fed diet containing 8% and 12% inclusion levels had the lowest value of PWG 26.7%, 37.5% and PER 0.66, 0.68 respectively with highest FCR 3.6.  Therefore,4% of  fermented millet could be included in the nutrition of African cat fish fingerlings  any adverse eefect. Keywords: Pennisetum americanum, Fermentation, Haematology, Feed conversion ratio and percentage inclusion leve

Socio-Economics Impacts Of Erin-Ijesha Water Fall, Erin-Ijesha, Osun State, Nigeria

The study examines the socio – economic impact of Erin Ijesha waterfall, Erin Ijesha in Osun State in Nigeria. Another name for the waterfall is Olumirin Waterfall which is situated within the enclave of Erin Garden. Structured questionnaires were used to elicit information from respondents on the impacts of the waterfall within the community and the State in general. Direct benefits derived from the waterfall include: drinking water, irrigation for agricultural land, tourism activities, fishing and it has contributed significantly to the overall well -being of the people of the area. It was discovered that the full potentials of the waterfall are yet to be harnessed due to lack of commitment from stakeholders especially the Government to invest in the development of the waterfall. Developing the waterfall will not only be a source of revenue to the government, it will equally generate substantial employment, thus reducing the burden of unemployment in the State and the Country at large. KEYWORDS: Waterfall, Socio-economic, Impact, Potential, Harnes

On the Classification of Gasoline-fuelled Engine Exhaust Fume Related Faults Using Electronic Nose and Principal Component Analysis

The efficiency and effectiveness of every equipment or system is of paramount concern to both the manufacturers and theend users, which necessitates equipment condition monitoring schemes. Intelligent fault diagnosis system using patternrecognition tools can be developed from the result of the condition monitoring. A prototype electronic nose that uses array ofbroadly tuned Taguchi metal oxide sensors was used to carry out condition monitoring of automobile engine using itsexhaust fumes with principal component analysis (PCA) as pattern recognition tool for diagnosing some exhaust relatedfaults. The results showed that the following automobile engine faults; plug-not-firing faults and loss of compression faultswere diagnosable from the automobile exhaust fumes very well with average classification accuracy of 91%.Key words: Electronic nose, Condition Monitoring, Automobile, Fault, Diagnosis, PCA

Assessment of Landfill-emitted Gaseous Pollutants and Particulate Matters in Alimosho Local Government of Lagos state, Nigeria

Information on landfill-emitted pollutants in Nigeria cities has consequently become a priority. This study was designed to assess the air quality of landfill sites and the nearby communities in the Alimosho Local Government Area of Lagos state, Nigeria. Five public landfills in use since about thirty years ago were chosen for this study. A lightly populated area, free from other sources of air pollution served as control. Target points for the study were the centre of landfill (CLF), 50M from CLF, 100M from CLF, and a radius of 100M away from landfill. Levels of selected gaseous pollutants (NO2, O3, H2S and CO) and particulate matters (PM2.5 and PM10) were determined in the landfill environments and control (unpolluted area), using Aeroqual Series 500 with sensors for NO2, O3, H2S, CO, PM2.5 and PM10. The result showed that levels of H2S were significantly (p<0.001) higher at the CLF, 50M from CLF and 100M from CLF compared with unpolluted area. There was no significant (p>0.05) difference when the level of H2S in 100M radius was compared with the unpolluted area. Levels of CO were significantly (p<0.001) higher at the CLF, 50M from CLF, 100M from CLF and 100M radius compared with unpolluted area. The levels of O3 were significantly (p<0.001) higher at the CLF, 50M from CLF, 100M from CLF and 100M radius compared with unpolluted area. Levels of VOC were significantly (p<0.001) higher at the CLF, 50M from CLF, 100M from CLF and 100M radius compared with unpolluted area. The levels of NO2 were significantly (p<0.001) higher at the CLF, 50M from CLF, 100M from CLF and 100M radius compared with the unpolluted area. The levels of PM2.5 increased significantly (p<0.001) at the CLF, 50M from CLF, 100M from CLF and 100M radius compared with the unpolluted area. The levels of PM10 were also significantly (p< 0.001) higher at the CLF, 50M from CLF, 100M from CLF and 100M radius compared with the unpolluted area. In conclusion, communities close to landfills may be polluted with toxic gases and particulate matters. Further investigation is needed to validate the safe distance of residential areas from landfills to avert the risks of toxicity associated with gaseous pollutants

Anthropometric studies for designing to fit gari-frying workers

 Work system and product design require anthropometric data of the user population relevant to the facility in order to have safe operation in service as well as increase user satisfaction and efficiency. Designing to fit gari-frying workers in each of the southwestern states in Nigeria is geared towards this end. The age, weight and twenty-five body dimensions of 120 gari-frying workers in Lagos, Ogun, Oyo, Osun, Ondo and Ekiti, selected by random sampling, were measured. The body dimensions include stature, shoulder height, sitting height, eye height, forward grip reach, buttock-popliteal height, buttock-knee length, knee height, thigh clearance, forearm-to-forearm breadth, waist depth, elbow rest height, knuckle height, elbow grip length, hip breadth, hand length, hand breadth, hand thickness, grip span and lumbar height. SPSS 20 software was used to perform statistical analysis to determine the mean, standard deviation, minimum and maximum values, 2nd, 5th, 25th, 50th, 75th and 95th percentiles for each state. Ogun state was used as a control, against which means of body dimension data, collected from other states, were compared using paired sample t-test. The results revealed that some of the body dimensions showed significant difference across the states at P≤0.05 with Oyo having more anthropometric parameters that differ from that of Ogun and Ondo having the least. Between 11.42% and 24.25% difference in the mean age, weight and lumbar height was observed in all the states. Osun state has the highest mean BMI and BSA values of 32.38 kg/m2 and 1.82 m2, respectively. These results are the required data for the design of facility and products for gari-frying workers as well as in similar women workspaces, especially in processing centres

Reliability of Some Clinical Parameters for Field Diagnosis of African Animal Trypanosomosis in Cattle

Presumptive and inaccurate diagnosis of cattle trypanosomosis among field veterinarians has led to misuse of trypanocides, development of drug resistance, toxicities and huge economic losses. This study assessed the reliability, specificity and sensitivity of some identified trypanosomosis associated signalments (anaemia using FAMACHA® guide, body condition score (BCS), superficial lymph nodes enlargement and jugular pulsation) as field diagnostic parameters. Blood and faecal samples were collected from 273 subjectively selected cattle for the determination of packed cell volume (PCV) and screening for trypanosome, and for helminth egg using McMaster technique, respectively. Data obtained from assessment of packed cell volume based on BCS, FAMANCHA score, superficial lymph nodes enlargement and jugular pulsation were analyzed using descriptive statistics and Chi square, while comparison of data using independent student ttest and one-way ANOVA was similarly conducted. Of the screened cattle, 16.5% (45/273) were positive for trypanosome. Single infection due to Trypanosoma spp. was found in 13.5% (37/273) cattle, while 2.9% (8/273) had trypanosome concurrently with Babesia spp. or helminth infections. The prevalence of Trypanosoma infection was higher in animals with mild or moderately pale mucous membrane, slight emaciation, palpable superficial lymph nodes and pulsating jugular vein. The mean PCV of Trypanosoma infected cattle (27.65±0.056) was lower than in non-infected cattle (31.30±0.36) (p<0.05). Based on the jugular pulsation status, enlargement of the superficial lymph nodes, trypanosomosis state and Famancha category, there was no significant (p<0.05) variation in the PCV of the examined cattle. A negative and low correlation (r = -0.054) existed between BCS and FAMACHA® anaemia score. Each of the clinical diagnostic parameters showed poor sensitivity when employed separately, but the sensitivity improved when applied together and showed 80% specificity to Trypanosoma infection. The results of the present study showed that Trypanosoma infected cattle were associated with anaemia, emaciation, weight loss, jugular pulsation and lymphadenophathy. Key Words: Trypanosomosis, Diagnosis, Cattle, Anaemia, Treatmen

Population structure and evolutionary history of the greater cane rat (Thryonomys swinderianus) from the Guinean Forests of West Africa

Grasscutter (Thryonomys swinderianus) is a large-body old world rodent found in sub-Saharan Africa. The body size and the unique taste of the meat of this major crop pest have made it a target of intense hunting and a potential consideration as a micro-livestock. However, there is insufficient knowledge on the genetic diversity of its populations across African Guinean forests. Herein, we investigated the genetic diversity, population structures and evolutionary history of seven Nigerian wild grasscutter populations together with individuals from Cameroon, Republic of Benin, and Ghana, using five mitochondrial fragments, including D-loop and cytochrome b (CYTB). D-loop haplotype diversity ranged from 0.571 (± 0.149) in Republic of Benin to 0.921 (± 0.013) in Ghana. Within Nigeria, the haplotype diversity ranged from 0.659 (± 0.059) in Cross River to 0.837 (± 0.075) in Ondo subpopulation. The fixation index (FST), haplotype frequency distribution and analysis of molecular variance revealed varying levels of population structures across populations. No significant signature of population contraction was detected in the grasscutter populations. Evolutionary analyses of CYTB suggests that South African population might have diverged from other populations about 6.1 (2.6–10.18, 95% CI) MYA. Taken together, this study reveals the population status and evolutionary history of grasscutter populations in the region

Factors associated with spontaneous stone passage in a contemporary cohort of patients presenting with acute ureteric colic. Results from the MIMIC Study (A Multi-centre cohort study evaluating the role of Inflammatory Markers in patients presenting with acute ureteric Colic)

Objectives There is conflicting data on the role of white blood cell count (WBC) and other inflammatory markers in spontaneous stone passage in patients with acute ureteric colic. The aim of the study was to assess the relationship of WBC and other routinely collected inflammatory and clinical markers including stone size, stone position and Medically Expulsive Therapy use (MET) with spontaneous stone passage (SSP) in a large contemporary cohort of patients with acute ureteric colic. Subjects and Methods Multi‐centre retrospective cohort study coordinated by the British Urology Researchers in Surgical Training (BURST) Research Collaborative at 71 secondary care hospitals across 4 countries (United Kingdom, Republic of Ireland, Australia and New Zealand). 4170 patients presented with acute ureteric colic and a computer tomography confirmed single ureteric stone. Our primary outcome measure was SSP as defined by the absence of need for intervention to assist stone passage. Multivariable mixed effects logistic regression was used to explore the relationship between key patient factors and SSP. Results 2518 patients were discharged with conservative management and had further follow up with a SSP rate of 74% (n = 1874/2518). Sepsis after discharge with conservative management was reported in 0.6% (n = 16/2518). On multivariable analysis neither WBC, Neutrophils or CRP were seen to predict SSP, with an adjusted OR of 0.97 [95% CI 0.91 to 1.04, p = 0.38], 1.06 [95% CI 0.99 to 1.13, p = 0.1] and 1.00 [95% CI 0.99 to 1.00, p = 0.17], respectively. Medical expulsive therapy (MET) also did not predict SSP [adjusted OR 1.11 [95% CI 0.76 to 1.61]). However, stone size and stone position were significant predictors. SSP for stones 7mm. For stones in the upper ureter the SSP rate was 52% [95% CI 48 to 56], middle ureter was 70% [95% CI 64 to 76], and lower ureter was 83% [95% CI 81 to 85]. Conclusion In contrast to the previously published literature, we found that in patients with acute ureteric colic who are discharged with initial conservative management, neither WBC, Neutrophil count or CRP help determine the likelihood of spontaneous stone passage. We also found no overall benefit from the use of MET. Stone size and position are important predictors and our findings represent the most comprehensive stone passage rates for each mm increase in stone size from a large contemporary cohort adjusting for key potential confounders. We anticipate that these data will aid clinicians managing patients with acute ureteric colic and help guide management decisions and the need for intervention

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic