13 research outputs found
Individual and combined soy isoflavones exert differential effects on metastatic cancer progression
- Author
- A Jemal
- A Schlachterman
- A Vincent
- A Wu
- AA Franke
- AF Chambers
- AF Chambers
- AJ Ridley
- AL Carlson
- AL Murkies
- Alina De La Mota-Peynado
- AV Singh
- B Nachmias
- BD Manning
- BG Chrzan
- BW Vanden
- CA Lamartiniere
- CD Allred
- D Fonseca
- D Gallo
- D Li
- D Silvera
- DB Conze
- DM Brownson
- E Krepela
- Elisa Otero-Franqui
- F Ramirez-Valle
- FM Vega
- H Iishi
- HA Ward
- HG Farina
- I Rowland
- JA Lavigne
- JE Price
- JF Harms
- JM Lizcano
- Joel Martinez
- JR Graff
- JR Graff
- JW Clark
- JW Lampe
- KM Bussard
- L Castillo-Pichardo
- L Stephens
- LH El Touny
- Luis A. Cubano
- M Lacroix
- M Lakshman
- M Messina
- Michelle M. Martínez-Montemayor
- MS Sakla
- MZ Fang
- N Kumar
- N Rabiau
- OC Kousidou
- PA Murphy
- PA Phadke
- PJ Magee
- RC Santell
- RK Vadlamudi
- S Braunstein
- S Jin
- S Rice
- S Sellappan
- S Zhou
- SA Vantyghem
- Suranganie Dharmawardhane
- TG Whitsett Jr
- X Huang
- XO Shu
- Y Guo
- Y Li
- Y Su
- YH Ju
- YH Shon
- YJ Jeng
- Z Mai
- Z Mai
- ZM Shao
- ZM Shao
- Publication venue
- Springer Netherlands
- Publication date
- 01/01/2010
- Field of study
To investigate the effects soy isoflavones in established cancers, the role of genistein, daidzein, and combined soy isoflavones was studied on progression of subcutaneous tumors in nude mice created from green fluorescent protein (GFP) tagged-MDA-MB-435 cells. Following tumor establishment, mice were gavaged with vehicle or genistein or daidzein at 10 mg/kg body weight (BW) or a combination of genistein (10 mg/kg BW), daidzein (9 mg/kg BW), and glycitein (1 mg/kg BW) three times per week. Tumor progression was quantified by whole body fluorescence image analysis followed by microscopic image analysis of excised organs for metastases. Results show that daidzein increased while genistein decreased mammary tumor growth by 38 and 33% respectively, compared to vehicle. Daidzein increased lung and heart metastases while genistein decreased bone and liver metastases. Combined soy isoflavones did not affect primary tumor growth but increased metastasis to all organs tested, which include lung, liver, heart, kidney, and bones. Phosphoinositide-3-kinase (PI3-K) pathway real time PCR array analysis and western blotting of excised tumors demonstrate that genistein significantly downregulated 10/84 genes, including the Rho GTPases RHOA, RAC1, and CDC42 and their effector PAK1. Daidzein significantly upregulated 9/84 genes that regulate proliferation and protein synthesis including EIF4G1, eIF4E, and survivin protein levels. Combined soy treatment significantly increased gene and protein levels of EIF4E and decreased TIRAP gene expression. Differential regulation of Rho GTPases, initiation factors, and survivin may account for the disparate responses of breast cancers to genistein and daidzein diets. This study indicates that consumption of soy foods may increase metastasis
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
- Author
- Abbas Sh
- Abbas Sh
- Abbassi Oa
- Abbott T
- Abdelgadir Am
- Abdelrahman A
- Abdelrahman M
- Abdelrahman M
- Abdelwahed A
- Abellan M
- Abellán Am
- Abellán Am
- Abulafi M
- Acharya A
- Acosta A
- Adam Me
- Adams Re
- Adegbola So
- Adegbola So
- Adimonye A
- Adnan M
- Afshar S
- Agresta F
- Agua Ia
- Aguayo Jl
- Agudo Ar
- Ahad A
- Ahel J
- Ahern Dp
- Ahmad A
- Ahmed B
- Ahmed G
- Ahmed Os
- Ahmed Os
- Ahmed S
- Ainsworth P
- Ais G
- Ais G
- Aisoni F
- Akbari K
- Akhtar K
- Akinsola O
- Akram F
- Al-Faham Z
- Al-Khafaji N
- Al-Khyatt W
- Al-Musawi S
- Al-Sarireh B
- Al-Sheikh M
- Alagna V
- Alani M
- Alberca-Paramo A
- Aldrey I
- Alexander R
- Alhammali T
- Alhammali T
- Ali M
- Aljorfi A
- Allen M
- Allington J
- Alonzo A
- Alshafei A
- Altomare Ma
- Alvarez Cm
- Alvarez E
- Alvarez-Gallego M
- Amaducci E
- Amarasinghe R
- Amayo A
- Ambrona-Zafra D
- Amin V
- Ammendola M
- Amtul N
- Amtul N
- Amuthalingam T
- Anandan L
- Anania G
- Anania M
- Anderson Dj
- Anderson O
- Andolfi E
- Andreani Sm
- Andreani Sm
- Andrews B
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- Angelieri D
- Angelini M
- Angrisani M
- Anguita F
- Ansaloni L
- Ansari A
- Aravind B
- Archer Je
- Arcuri Ga
- Arcuri Ga
- Aremu Ma
- Arenal-Vera Jj
- Aresu S
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- Argenio G
- Argenti F
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- Lek C
- Lennox-Warburton Hc
- Leon C
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- Leusink A
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- Lopez-Ruiz Ja
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- Panda N
- Panda N
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- Pandey V
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- Pareja-Ciuró F
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- Pascua-Sole M
- Pascual-Miguelañez I
- Pasquali S
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F.
- Pata G
- Pata G
- Pata G
- Patel As
- Patel By
- Patel By
- Patel C
- Patel H
- Patel Mm
- Patel N
- Patel Pk
- Patel Rt
- Patil Sd
- Patti S
- Pau R
- Payne Cj
- Payne Re
- Payá-Llorente C
- Payá-Llorente C
- Peacock M
- Pearce J
- Pearce J
- Pearce L
- Pearce L
- Pearson R
- Pedder A
- Peirce Cb
- Peiris Gb
- Peixoto R
- Peleki A
- Peleki A
- Pellegrino L
- Pellicanò Ga
- Pellicer-Franco E
- Pellino G
- Pento V
- Pento V
- Peponis C
- Peprah D
- Pereira A
- Pereira Am
- Pereira J
- Pereira-Mosquera E
- Perera Mi
- Perez-Calvo J
- Perin A
- Pertile D
- Pertile D
- Peña-Barturen C
- Phelan L
- Photiou D
- Pierre R
- Pietrabissa A
- Pigem A
- Pila U
- Pilkington Jp
- Pineño-Flores C
- Pinillos-Somalo A
- Pinkney Td
- Pinkney Td
- Pinkney Td
- Pinna E
- Pino-Perez O
- Pirari Pf
- Pisanu A
- Piu F
- Planellas P
- Plua-Muniz Kt
- Poacher A
- Podda F
- Podda M
- Podda M
- Podda M
- Poillucci G
- Pollard H
- Ponchietti L
- Popova D
- Poudevigne M
- Prats Ma
- Prideaux A
- Prieto-Nieto Mi
- Primo Jc
- Pronin S
- Provenza G
- Puerta E
- Pulighe F
- Pullabatla-Venkata Up
- Punj S
- Pérez-Sanchez Le
- Quddus A
- Quill S
- Quinn Em
- Quinn Hc
- Rabie M
- Rabie Ma
- Rabie Mr
- Radwan Rw
- Radwan Rw
- Rahim A
- Rahman M
- Rahmani Ls
- Rajagopal S
- Rajaram R
- Rajaretnam N
- Rajjoub Y
- Rallage H
- Ramcharan S
- Ramirez L
- Ramirez-Redondo Aa
- Ramos Xh
- Ramos-Bernado Mi
- Ramírez-Faraco M
- Ranathunga S
- Rangarajan K
- Rao M
- Rao V
- Raofi A
- Rashid M
- Rate A
- Ravindran R
- Raymond M
- Raza Ss
- Recreo Ac
- Reddy A
- Reddy A
- Redmond Ae
- Redondo E
- Redondo E
- Redondo-Calvo Fj
- Reese G
- Regina G
- Rehman S
- Rehman S
- Rekhraj S
- Ren Kz
- Renshaw S
- Renshaw S
- Renzi Cr
- Resende Fm
- Rezacova M
- Rezvani S
- Riaz W
- Riba-Combatti L
- Ribaudo M
- Ribeiro B
- Rich Je
- Richardson Td
- Ridaura N
- Riera E
- Rigby S
- Rigney B
- Rinkoff S
- Ripoli Mc
- Robb Hd
- Robertson C
- Robinson A
- Robinson A
- Robinson D
- Robinson D
- Rocha R
- Rodger V
- Rodicio-Miravalles Jl
- Rodriguez L
- Rodriguez-Lopez M
- Rodriguez-Lopez M
- Rodriguez-Lopez M
- Rodríguez Ec
- Rojo Ja
- Roldán-Ortiz S
- Rolph R
- Romano J
- Romano R
- Romario Uf
- Romoli L
- Roncero Ls
- Ronda Rn
- Roomi S
- Rosa Mj
- Rosat A
- Roscio F
- Roscio F
- Roscio F
- Rossi C
- Rossi D
- Rossi Gm
- Roth N
- Rothnie K
- Roxburgh C
- Roy C
- Ruano A
- Rubbini M
- Rudland I
- Ruffolo C
- Rufo E
- Ruggiu Gv
- Ruiz-Marín M
- Ruiz-Marín M
- Rupani S
- Rupasinghe Sn
- Rupasinghe Sn
- Rutherford Dg
- Ruzvidzo F
- Ruzzenente A
- Saad M
- Saad M
- Saavedra-Chacón M
- Saba A
- Sabia D
- Sacco R
- Sacks R
- Sadek S
- Saghir N
- Sagnotta A
- Sagnotta A
- Saha A
- Sahay Sj
- Sahnan K
- Sahnan K
- Sainz B
- Sainz B
- Sajid Ms
- Salama Y
- Salamone G
- Salamone G
- Salamone G
- Salamone G
- Salandini Mc
- Salem A
- Salim S
- Salva Ab
- Salvador H
- Samartin C
- Sammarco G
- Sammarco G
- Samuel M
- Sana S
- Sanchez Er
- Sanchez Er
- Sanchez L
- Sanchez-Garcia S
- Sanchez-Guillen L
- Sanchez-Guillen L
- Sanchez-Martinez A
- Sancho-Muriel J
- Sandu L
- Sanna S
- Santamaria C
- Santamaría Pc
- Santarrufina-Martínez S
- Santos Sc
- Santurro L
- Sanz-Navarro S
- Sarmah P
- Sarmah P
- Sarmah P
- Sarveswaran J
- Sasia D
- Sasia D
- Saunders S
- Savill A
- Savino G
- Savino G
- Savioli F
- Scabini S
- Scabini S
- Scabini S
- Scandroglio Is
- Scanlon K
- Scatizzi M
- Scialandrone G
- Scricciolo M
- Sebastian Jf
- Sebastián-Tomás Jc
- Seddon Tc
- Segalini E
- Segura-Sampedro Jj
- Sena G
- Sena-Ruiz F
- Seneviratne N
- Sepe C
- Serventi F
- Serventi F
- Seth M
- Setshwaelo T
- Sezen E
- Sgardelis P
- Sgrò A
- Sgrò A
- Sgrò A
- Shah J
- Shah K
- Shah Sm
- Shah Sm
- Shaikh Ia
- Shakoor Z
- Shanmuganathan V
- Shanmugarajah K
- Sharma A
- Sharma A
- Sharma P
- Sharp Ol
- Sharp Ol
- Shaw Av
- Shepherd Ja
- Sherif Ma
- Shet S
- Shetty Vd
- Shingler G
- Shiwani Mh
- Shrestha D
- Shurlock J
- Sian T
- Siaw O
- Siddique K
- Siddiqui Mn
- Siddiqui Za
- Sierra-Grañón Je
- Siggens Kl
- Sihra N
- Silva A
- Silva I
- Silvestri V
- Simioni A
- Simmonds L
- Simmonds L
- Simo V
- Simoes J
- Simpson Dj
- Singh A
- Singh J
- Singh P
- Singh S
- Singhal T
- Singhal T
- Sivaloganathan P
- Skalamera I
- Skerritt C
- Slezak I
- Smallcombe N
- Smart Cj
- Smart Cj
- Smart Nj
- Smart Nj
- Smoker H
- Soares A. S.
- Soares As
- Soares As
- Soares As
- Soares As
- Soares As
- Soh B
- Solaini L
- Solar-García L
- Soliani P
- Solinas L
- Sooriyamoorthy T
- Soria-Aledo V
- Soria-Aledo V
- Soriano Jt
- Sorrentino L
- Sousa Hs
- Souter J
- Sparta C
- Spaziani A
- Speake D
- Speake D
- Springate El
- Sreedharan L
- Sreedharan L
- Staderini F
- Stecca T
- Stella M
- Stephens Gf
- Stephens Gf
- Stevenson R
- Stewart Dj
- Stoica I
- Storey R
- Stoyanov Ti
- Strachan E
- Strange Ja
- Stubbs Bm
- Stupalkowska W
- Stupalkowska W
- Suarez-Cabrera A
- Suero Ca
- Sultana A
- Summerfield L
- Sunter H
- Surg Pt
- Suriyakumar S
- Suárez-Sánchez A
- Swords C
- Symons N
- Szentpali K
- Szucs A
- Szucs A
- Sánchez-Cifuentes A
- Sánchez-Fuentes Mn
- Sánchez-Rubio M
- Tabain V
- Taglietti L
- Tague Le
- Tahir W
- Tailor K
- Tallon-Aguilar L
- Tallon-Aguilar L
- Tamayo-López Mj
- Tamborska A
- Tamini N
- Tamini N
- Tamini N
- Tan Cy
- Tan Cy
- Tan E
- Tan Hl
- Tan S
- Tang Am
- Tapiolas I
- Tarazi M
- Tatulli F
- Tay Yh
- Tayeh S
- Taylor M
- Taylor Ns
- Taylor Ns
- Taze D
- Tee A
- Tejero-Pintor Fj
- Tenconi Sm
- Tezas S
- Thaha Ma
- Thakral N
- Thakur D
- Thava B
- Thavanesan N
- Thavanesan N
- Thaventhiran Aj
- Theodoropoulou K
- Thomas At
- Thomas L
- Thompson C
- Thompson Db
- Thompson Db
- Thompson R
- Thompson R
- Thoukididou Sn
- Tiedt La
- Tiedt La
- Ting N
- Tinoco-González J
- Tinsley Bj
- Tognarelli Jm
- Tojal A
- Tokidis E
- Tomasoni M
- Tonini V
- Toomey D
- Toomey Db
- Torkington J
- Torkington J
- Torrado Aa
- Torrance A
- Torrance A
- Townsend Dc
- Townsend Dc
- Tozer Pj
- Trail M
- Trail M
- Trastulli S
- Trew F
- Trostchansky I
- Trujillo-Diaz Jj
- Tsang B
- Tudyka V
- Tudyka V
- Turnbull A
- Turner Ej
- Tutino R
- Twum-Barima Cs
- Twum-Barima Cs
- Tyler R
- Tyler R
- Ugarte-Sierra B
- Vacca A
- Vaccari S
- Vakis S
- Valente Pm
- Valiani Sv
- Vallejo-Bernad C
- Vallve-Bernal M
- Van Boxel Gi
- Vance-Daniel J
- Vannucchi A
- Varcada M
- Vargas-Pierola Hj
- Vaughan Em
- Vaughan Em
- Vazquez-Fernandez Ap
- Vega L
- Velchuru Vr
- Velho R
- Venkata Up
- Venkatasubramaniam Ak
- Venn Ml
- Venn Ml
- Venugopal R
- Verea S
- Veres T
- Veres T
- Verroiotou M
- Vescio G
- Vettoretto N
- Vigorita V
- Vijay V
- Vila-Zarate C
- Villarejo-Campos P
- Vinnicombe Z
- Viscosi F
- Vitish-Sharma P
- Viviani E
- Viñas Nl
- Vohra R
- Vohra R
- Vulcano I
- Waite K
- Walji Hd
- Walsh E
- Walsh Tn
- Walters Kj
- Walters U
- Wardle Bg
- Wardle Bg
- Wardle Sd
- Warren O
- Warren Oj
- Warusavitarne J
- Watfah J
- Watson N
- Wauchope J
- Weatherburn Lw
- Weaver J
- Weegenaar Cr
- Weegenaar Cr
- Welsh S
- Wensley F
- West H
- West H
- Wheatstone S
- Wheeler C
- Whewell He
- White F
- Whitehorn Se
- Whitehorn Se
- Whitehouse P
- Whiteman E
- Whittaker L
- Wiggill S
- Wijesundera K
- Wilcox G
- Wilkin R
- Wilkin R
- Wilkin R
- Wilkin R
- Wilkin R. J. W.
- Williams Gl
- Williams M
- Williams R
- Williams S
- Wilson Ej
- Wilson M
- Winter Dc
- Winter Dc
- Wolff J
- Wong A
- Wong C
- Wong J
- Wong J
- Wong Ml
- Wong Sy
- Woo R
- Wood Cs
- Woodrow C
- Woodward A
- Woodward B
- Woodward B
- Worku D
- Worku D
- Wright E
- Wright Hl
- Wu F
- Xidas A
- Yalamarthi S
- Yang P
- Yanni F
- Yardimci E
- Yasin T
- Yen Sk
- Yeung K
- Yeung K
- Yoganathan S
- Yoong S
- Youssef H
- Yow L
- Yow L
- Zaborowski A
- Zadi Az
- Zalla T
- Zarka Za
- Zarka Za
- Zarog Ma
- Zelazek M
- Zerpa C
- Zhang Ay
- Zhou S
- Zorrilla L
- Zuin M
- Zurleni Tz
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Background
Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.
Methods
A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).
Results
Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).
Conclusion
Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified
Beam pump combination for fiber lasers
- Author
- Publication venue
- 'SPIE-Intl Soc Optical Eng'
- Publication date
- 01/01/2008
- Field of study
Polymorphisms in GSTT1 and GSTM1 genes as possible risk factors for susceptibility to breast cancer development and their influence in chemotherapy response: a systematic review
- Author
- A Garcia-Martinez
- A Oakley
- A Sohail
- AK Daly
- BM Krishna
- C Catsburg
- C Sui
- CK Anders
- CW Elston
- CZ Campos
- D Moher
- DM Townsend
- EA Rakha
- F Bray
- F Sebastiani
- G Di Pietro
- G Jaramillo-Rangel
- H Dirr
- H Fredholm
- HR He
- INCA
- IT Kiendrebeogo
- J Liu
- J Wang
- JD Boice Jr
- JD Hayes
- K Ahmed
- K Liu
- K Sapcharoen
- KF Windmill
- L Zhou
- LG Possuelo
- LN Al-Eitan
- M Almeida
- MC McFadyen
- MG Kakkoura
- N Weich
- NA Kalacas
- NK Zgheib
- NO Pandey
- O Soto-Quintana
- OC Martinez-Ramirez
- P Hruska
- P Yuan
- R Yerushalmi
- S Eslami
- S Li
- S Singh
- S Tulsyan
- SS Malik
- SS Mostafavi
- X Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Pharmacological treatment of hemorrhoids: a narrative review
- Author
- Abramowitz L
- Abramowitz L
- Abramowitz L
- Abramowitz L
- Allain H
- Alonso-Coello P
- Alonso-Coello P
- Altomare DF
- Altomare DF
- Arnold K
- Ba-bai-ke-re MM
- Cataldo P
- Cesarone MR
- Chan KKW
- Ciapponi A
- Cirino G
- De Cecco L
- Di Carlo A
- Donato F Altomare
- Dressler H
- Espinosa DJ
- Gass OC
- Gazet JC
- Gibson GR
- Gojnic M
- Haas PA
- Han W
- Ho YH
- Ibanez L
- Ivana Giannini
- Johanson JF
- Joksimovic N
- Khubchandani IT
- Knoch HG
- La Torre F
- Lef f E
- Lestar B
- Lodi A
- Lyseng-Williamson KA
- Maestre Y
- Martinez MJ
- Menteş BB
- Misra MC
- Moesgaard F
- Perera N
- Perrotti P
- Pollinzi V
- Quijano CE
- Ramirez P
- Rivadeneira DE
- Schrezenmeir J
- Shafik A
- Tejirian T
- Thomson WH
- Tjandra JJ
- van den Berg M
- Wienert V
- Willis S
- Zapater P
- Publication venue
- 'Informa Healthcare'
- Publication date
- Field of study
International Multidisciplinary Consensus Conference on Multimodality Monitoring: ICU Processes of Care
- Author
- A Coester
- A Cook
- A Ingeman
- A Ingeman
- A Meretoja
- A Nellore
- A Rhodes
- AH Kramer
- AH Kramer
- AI Qureshi
- AI Qureshi
- AM Sonabend
- American Thoracic Society
- BA McKinley
- BH Wittekamp
- BN Gomes Silva
- BP Keller
- C Eker
- C Graffagnino
- C Lerch
- C VanGilder
- CA van Nieuwenhoven
- CC Yang
- CS Cocanour
- D Anderson
- D Bird
- D Stradling
- DA Godoy
- DA Harrison
- DA Reiff
- David A. Horowitz
- DE Craven
- DE Griesdale
- DJ Dries
- DM Green
- DR Thomas
- DT Huang
- E Henneman
- E Henneman
- E Schmutzhard
- EC Jauch
- EE Smith
- EH de Laat
- EKG Reilly
- EM Bershad
- ES Connolly Jr
- F Bilotta
- F Bilotta
- F Bilotta
- F Gandia-Martinez
- FA Manian
- G Van den Berghe
- G Van den Berghe
- H Leblebicioglu
- HA Biersteker
- HC Patel
- HF Lingsma
- HK Wang
- I Meynaar
- I Safaz
- J Jacobi
- J Rello
- JA Quinn
- JD Burns
- JDJ Palminteri
- JE Mangino
- JI Suarez
- JM Kahn
- JP Braun
- JP Lott
- JR Cherry-Bukowiec
- JS McKinney
- JSMDF Krinsley
- K Elf
- K Matsushima
- K Wright
- KC Sihler
- KE Anger
- KM Sundar
- L Bouadma
- L Bouadma
- L Knopf
- LG Glance
- LH Schwamm
- LJ Weireter Jr
- LR Schmeltz
- M Anderson
- M de Vos
- M Dennis
- M Dhandapani
- M Egi
- M Naccarato
- M Oddo
- M Rahman
- M Vukic
- MA Bouderka
- MA Mirski
- MC Byrnes
- ME Kutcher
- ME Rupp
- ME Stone Jr
- MH Kollef
- MH Kollef
- MH Kollef
- MN Diringer
- Molly M. McNett
- N Ahmed
- N Safdar
- O Samuels
- OC Tablan
- OL Cremer
- P Ramirez
- P Talving
- P Vespa
- P Vespa
- P Wilczweski
- PE Warme
- PHJ van der Voort
- PJ Pronovost
- PJ Pronovost
- PM Olaechea
- PN Varelas
- PN Varelas
- PN Varelas
- PN Varelas
- PNAT Varelas
- PW Stone
- R Shulman
- RO Darouiche
- RR Dudley
- RS Wiener
- S Finfer
- S Kanji
- S Magnoni
- S Palmer
- SA Josephson
- SC Cramer
- SC Gale
- SE Coffin
- SJ Finney
- SM Fakhry
- SO Labeau
- SW English
- T Lansford
- T Scudday
- TI Gropen
- TJ Clayton
- TW Vitaz
- WL Wahl
- X Hui
- X Wang
- Y Kasuya
- YM Arabi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A Search for Ultra-high-energy Neutrinos from TXS 0506+056 Using the Pierre Auger Observatory
- Author
- Aab A
- Abreu P
- Aglietta M
- Albuquerque IFM
- Albury JM
- Allekotte I
- Almela A
- Alvarez-Muniz J
- Anastasi GA
- Anchordoqui L
- Andrada B
- Andringa S
- Aramo C
- Asorey H
- Assis P
- Avila G
- Awad AK
- Badescu AM
- Bakalova A
- Balaceanu A
- Barbato F
- Baur S
- Becker KH
- Bellido JA
- Berat C
- Berisso MG
- Bertaina ME
- Bertou X
- Biermann PL
- Biteau J
- Blanco A
- Blazek J
- Bleve C
- Bohaacovaa M
- Boncioli D
- Bonifazi C
- Borodai N
- Botti AM
- Brack J
- Bravo OM
- Bretz T
- Bridgeman A
- Briechle FL
- Buchholz P
- Bueno A
- Buitink S
- Buscemi M
- Caballero-Mora KS
- Caccianiga L
- Calcagni L
- Cancio A
- Canfora F
- Caracas I
- Carceller JM
- Cardenas BV
- Caruso R
- Casado AL
- Castellina A
- Castillo JA
- Castro MLD
- Catalani F
- Cataldi G
- Cazon L
- Cerda M
- Cerutti ACC
- Chinellato JA
- Choi K
- Chudoba J
- Chytka L
- Clay RW
- Colalillo R
- Coleman A
- Coluccia MR
- Conceicao R
- Condorelli A
- Consolati G
- Contreras F
- Convenga F
- Cooper MJ
- Coutu S
- Covault CE
- D'Olivo JC
- Daniel B
- Dasso S
- Daumiller K
- Dawson BR
- Day JA
- de Almeida RM
- de Carvalho WR
- de Jong SJ
- De Mauro G
- De Mitri I
- de Oliveira J
- de Oliveira MAL
- de Souza V
- Debatin J
- del Rio M
- Deligny O
- Dhital N
- Di Matteo A
- Dobrigkeit C
- Dorosti Q
- dos Anjos RC
- Dova MT
- Dundovic A
- Ebr J
- Elipe GT
- Engel R
- Erdmann M
- Escobar CO
- Etchegoyen A
- Falcke H
- Farmer J
- Farrar G
- Fauth AC
- Fazzini N
- Feldbusch F
- Fenu F
- Ferreyro LP
- Figueira JM
- Filipcic A
- Freire MM
- Fujii T
- Fuster A
- Galicia JFV
- Garcia B
- Gemmeke H
- Gesualdi F
- Gherghel-Lascu A
- Ghia PL
- Giaccari U
- Giammarchi M
- Giller M
- Glombitza J
- Gobbi F
- Golup G
- Gomez JDS
- Gongora JP
- Gonzalez N
- Goos I
- Gora D
- Gorgi A
- Gottowik M
- Grubb TD
- Guarino F
- Guedes GP
- Guido E
- Hahn S
- Halliday R
- Hampel MR
- Hansen P
- Harari D
- Harrison TA
- Harvey VM
- Haungs A
- Hebbeker T
- Heck D
- Heimann P
- Hill GC
- Hojvat C
- Holt EM
- Homola P
- Horandel JR
- Horvath P
- Hrabovsky M
- Huege T
- Hulsman J
- Insolia A
- Isar PG
- Johnsen JA
- Jurysek J
- Kaapa A
- Kampert KH
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- Kemmerich N
- Kemp J
- Klages HO
- Kleifges M
- Kleinfeller J
- Kuempel D
- Lago BL
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- Lenok V
- Letessier-Selvon A
- Lhenry-Yvon I
- Lippmann OC
- Lo Presti D
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- Mancarella G
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- Mantsch P
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- Maris IC
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- Melo D
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- Merenda KD
- Mezek GK
- Michal S
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- Mockler D
- Mollerach S
- Montanet F
- Morello C
- Morlino G
- Mostafa M
- Muller AL
- Muller MA
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- Mussa R
- Namasaka WM
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- Nez LANU
- Niculescu-Oglinzanu M
- Niechciol M
- Nitz D
- Nosek D
- Novotny V
- Nozka L
- Nunez LA
- Olinto A
- Palatka M
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- Panetta MP
- Papenbreer P
- Parente G
- Parra A
- Pech M
- Pedreira F
- Peixoto CJT
- Pekala J
- Pelayo R
- Pena-Rodriguez J
- Pereira LAS
- Perlin M
- Perrone L
- Peters C
- Petrera S
- Phuntsok J
- Pierog T
- Pimenta M
- Pirronello V
- Platino M
- Poh J
- Pont B
- Porowski C
- Pothast M
- Prado RR
- Privitera P
- Prouza M
- Puyleart A
- Querchfeld S
- Quinn S
- Quispe IDV
- Ramos-Pollan R
- Rautenberg J
- Ravignani D
- Reininghaus M
- Ridky J
- Riehn F
- Risse M
- Ristori P
- Rizi V
- Rojo JR
- Roncoroni MJ
- Roth M
- Roulet E
- Rovero AC
- Ruehl P
- Saffi SJ
- Saftoiu A
- Salamida F
- Salazar H
- Salina G
- Sanchez F
- Santos E
- Santos EM
- Sarazin F
- Sarmento R
- Sarmiento-Cano C
- Sato R
- Savina P
- Schauer M
- Scherini V
- Schieler H
- Schimassek M
- Schimp M
- Schluter F
- Schmidt D
- Scholten O
- Schovanek P
- Schroder FG
- Schroder S
- Schumacher J
- Sciutto SJ
- Scornavacche M
- Shellard RC
- Sigl G
- Silli G
- Sima O
- Smida R
- Snow GR
- Sommers P
- Soriano JF
- Souchard J
- Squartini R
- Stadelmaier M
- Stanca D
- Stanic S
- Stasielak J
- Stassi P
- Stolpovskiy M
- Streich A
- Suarez-Duran M
- Sudholz T
- Suomijarvi T
- Supanitsky AD
- Supik J
- Szadkowski Z
- Taboada A
- Taborda OA
- Tapia A
- Timmermans C
- Tobiska P
- Tome B
- Travaini A
- Travnicek P
- Trini M
- Tueros M
- Ulrich R
- Unger M
- Urban M
- Valino I
- Valore L
- van Bodegom P
- van den Berg AM
- van Vliet A
- Varela E
- Vasquez-Ramirez A
- Veberic D
- Ventura C
- Verzi V
- Vicha J
- Villasenor L
- Vink J
- Vitale PFG
- Vorobiov S
- Wahlberg H
- Watson AA
- Weber M
- Weindl A
- Wiedenski M
- Wiencke L
- Wilczynski H
- Winchen T
- Wirtz M
- Wittkowski D
- Wundheiler B
- Yang L
- Yushkov A
- Zas E
- Zavrtanik D
- Zavrtanik M
- Zehrer L
- Zepeda A
- Zimmermann B
- Ziolkowski M
- Zuccarello F
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2020
- Field of study
Results of a search for ultra-high-energy neutrinos with the Pierre Auger Observatory from the direction of the blazar TXS 0506+056 are presented. They were obtained as part of the follow-up that stemmed from the detection of high-energy neutrinos and gamma rays with IceCube, Fermi-LAT, MAGIC, and other detectors of electromagnetic radiation in several bands. The Pierre Auger Observatory is sensitive to neutrinos in the energy range from 100 PeV to 100 EeV and in the zenith-angle range from = 60 degrees to = 95 degrees, where the zenith angle is measured from the vertical direction. No neutrinos from the direction of TXS 0506+056 have been found. The results were analyzed in three periods: one of 6 months around the detection of IceCube-170922 A, coinciding with a flare period of TXS 0506+056, a second one of 110 days during which the IceCube collaboration found an excess of 13 neutrinos from a direction compatible with TXS 0506+056, and a third one from 2004 January 1 up to 2018 August 31, over which the Pierre Auger Observatory has been taking data. The sensitivity of the Observatory is addressed for different spectral indices by considering the fluxes that would induce a single expected event during the observation period. For indices compatible with those measured by the IceCube collaboration the expected number of neutrinos at the Observatory is well below one. Spectral indices as hard as 1.5 would have to apply in this energy range to expect a single event to have been detected
Vascular Dysfunction in Mother and Offspring During Preeclampsia: Contributions from Latin-American Countries
- Author
- A Fraser
- A Khalil
- A Leanos-Miranda
- A Leanos-Miranda
- A Perez-Sepulveda
- AB Wallis
- AC Henriques
- AC Palei
- AG Shammas
- AJ Whitehouse
- Alicia E. Damiano
- AM Aukes
- AM Aukes
- AM Germain
- American College of O Gynecologists, Task Force on Hypertension in P
- Angela Cadavid
- AR Khowaja
- AS Kvehaugen
- B Huppertz
- B Sibai
- BE Vikse
- BE Vikse
- BJ Acauan Filho
- C Aban
- C Escudero
- C Kienast
- C Ronsmans
- C Wadsack
- CA Escudero
- CA Oliveira
- CA Oliveira de
- Carlos Escudero
- Carlos Galaviz-Hernandez
- CF Wenceslau
- CG Julian
- CM McCarthy
- CM McCarthy
- CS Wu
- CS Wu
- CW Redman
- CW Redman
- D Enkhmaa
- D Verdegem
- DA Lawlor
- DB Chen
- DB Ehrenthal
- DE Henao
- DP Leonardo
- DS Boeldt
- DS Tannetta
- E Abalos
- E Abalos
- E Kajantie
- E Teran
- E Teran
- E Teran
- E Teran
- E Teran
- EF Davis
- EF Davis
- EM Dantas
- Enrique Teran
- EW Harville
- EW Seely
- F Crovetto
- F Dang
- Fernanda Regina Giachini
- G Fu
- G Goynumer
- G Valdes
- GD Yesil
- GJ Burton
- GJ Burton
- GM Rodgers
- GZ Yu
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- H Brunner
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- I Afzal-Ahmed
- I Agarwal
- I Herraiz
- IC Weel
- IP Gaugler-Senden
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- JA Hutcheon
- James M. Roberts
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- JM Roberts
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- JP Kusanovic
- Julio Bueno
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- KS Khan
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- L Diaz-Olguin
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- LC Sanchez-Aranguren
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- M Silasi
- M Widmer
- MA Hanson
- Marta Viana
- Martha Sosa-Macias
- Martin Alcala
- María Calderón-Domínguez
- María P. Ramos
- MB Franz
- MC Brown
- MC Paez
- ME Penning
- MF Garces
- MI Griffith
- MI March
- MJ Wiegman
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- MK Sandvik
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- ML Mongraw-Chaffin
- ML Urquia
- MT Ratsep
- MT Ratsep
- MT Ratsep
- N Serrano-Diaz
- N Shahbazian
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- NE Poveda
- Nora Martinez
- O Gishti
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- P Casanello
- P Chedraui
- P Dadelszen von
- Patricia Asturizaga
- PJ Cheng
- PK Agatisa
- PM Cirillo
- PRA Bertoglia
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- RP Porreco
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- S Goulopoulou
- S Grand’Maison
- S Johnson
- S Sunderji
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- SE Maynard
- SE Maynard
- SJ Germain
- Sonia Clapes
- SW Cheng
- T Siepmann
- TL Weissgerber
- TL Weissgerber
- V Dietrich
- V Glover
- VC Sandrim
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- Victor Vitorino Lima
- VM Chamy
- VS Giorgi
- W Szymonowicz
- WM White
- X Xiong
- Y Lopez-Hernandez
- Y Palacios de Franco
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- 'Springer Science and Business Media LLC'
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Bibliography: longevity, ageing and parental age effects in Drosophila (1907–86)
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- A Balazs
- A Bucheton
- A Bucheton
- A Bucheton
- A Bucheton
- A Bucheton
- A Butz
- A Butz
- A Comfort
- A Comfort
- A Comfort
- A Damon
- A Durrant
- A Elens
- A Elens
- A Elens
- A Fleuriet
- A Fukatami
- A Grossman
- A Kamping
- A Labitte
- A Manning
- A Manning
- A Manning
- A Mohsin
- A Mohsin
- A Pruzan
- A Pruzan
- A Pruzan
- A Pruzan
- A Pruzan
- A Pruzan
- A Richardson
- A Richardson
- A Robertson
- A Schneider-Minder
- A Solima-Simmons
- A Takahashi
- A Takahashi
- AA Hoffmann
- AA Hoffmann
- AB Gould
- AB Gould
- AB Gould
- AB Robinson
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Economos
- AC Matheson
- AC Matheson
- AC Vann
- AD Bergner
- AF Yanders
- AF Yanders
- AF Yanders
- AF Yanders
- AH Kopelman
- AI Potapenko
- AI Potapenko
- AI Zotin
- AI Zuitin
- AJ Mill
- AJ Nappi
- AJ Nappi
- AM Clark
- AM Clark
- AM Clark
- AM Hannah
- AM Hannah
- AM Hasan
- AM Mourad
- AM Mourad
- AN Bozcuk
- AN Bozcuk
- AN Bozcuk
- AN Bozcuk
- AN Bozcuk
- AN Bozcuk
- AO Martinez
- AO Martinez
- AO Martinez
- AO Tantawy
- AO Tantawy
- AO Tantawy
- AO Tantawy
- AO Tantawy
- AO Tantawy
- AO Tantawy
- AP Jha
- AP Jha
- AP Mahowald
- AP Mange
- AP Scherbakov
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- AP Scherbakov
- AP Scherbakov
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- AS Robinson
- AS Weltman
- AT Beckenbach
- AV Nekrasova
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- B Borowsky
- B Burnet
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- B Charlesworth
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- B Minke
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- B Wallace
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- BL Strehler
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- BM Gonzalez
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- CA Andrews
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- S Ohba
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- T Aigaki
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- U Graf
- US Dept of Health Education and Welfare
- V Bochnig
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- VA Geodakyan
- VB Chernyshev
- VB Wigglesworth
- VFB Crowell
- VG Mitrofanov
- VG Mitrofanov
- VUS Jayasuriya
- VV Sacharov
- W Delden van
- W Delden van
- W Delden van
- W Delden van
- W Delden van
- W Delden Van
- W Goetsch
- W Goetsch
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- W Goetsch
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- W. E. Spivey
- W. E. Trout
- WA Calder
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- WAF Watson
- WD Atkinson
- WD Atkinson
- WE Trout
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- WJ Crozier
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- WJ Tadei
- WM Muir
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- WO Fenn
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- WS Klug
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- WW Alpatov
- WW Alpatov
- WW Anderson
- WW Anderson
- WW Doane
- WW Doane
- Y Carton
- Y Cohet
- Y Cohet
- Y Cohet
- Y Cohet
- Y Cohet
- Y Fiala
- Y Furruya
- Y Hiraizumi
- Y Hiraizumi
- Y Hiraizumi
- Y Hiraizumi
- Y Hiraizumi
- Y Hiraizumi
- Y Inouchi
- Y Melander
- Y Miyoshi
- Y Teranishi
- YAI Chernick
- YK Hihara
- YN Tobari
- ZI Ali
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1988
- Field of study
Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.
- Author
- Aawsaj Y
- Abad Gurumeta A
- Abad-Motos A
- Abate E
- Abatini C
- Abbadessa F
- Abbas AM
- Abbassi-Ghadi N
- Abbott D
- Abbott T
- Abbott TEF
- Abd Elazeem HAS
- Abdalla M
- Abdallah M
- Abdelaal SA
- Abdeldayem H
- Abdelkarem MM
- Abdelkarim M
- Abdelmajeed A
- Abdelrahman A
- Abdelrahman S
- Abdelsamed A
- Abdou M
- Abdulkareem A
- Abdulwahed E
- Abdur-Rahman L
- Abel MK
- Abellan M
- Abosamak NE
- Abou Chaar MK
- Abou-Khalil J
- Abouassi A
- Aboulkassem H
- Abreu da Silva A
- Abu Za'nouneh FJ
- Abu J
- Abu-Nayla I
- Abubakar A
- Abukhalaf S
- Acebes Garcia F
- Achalandabaso Boira M
- Acher A
- Acrich E
- Adamina M
- Adamina M
- Adamoli L
- Addae-Boateng E
- Ademuyiwa AO
- Aderombi A
- Adeyeye A
- Adiamah A
- Adishesh M
- Agapov M
- Agarwal A
- Aggarwal A
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agoston P
- Agrawal A
- Agresta F
- Aguado H
- Aguzzoli L
- Ahad S
- Ahmadi N
- Ahmed NR
- Ahmeidat A
- Ahn JH
- Aiken T
- Aime A
- Ajlan A
- Akalin M
- Akaydin E
- Akeel N
- Akgor U
- Akhtar MA
- Akilli H
- Akin E
- Akkour K
- Akkulak M
- Akmenkalne L
- Al Abdallah M
- Al Abdel S
- Al Awwad S
- Al Habes H
- Al Maadany FS
- Al Raddadi R
- AL Sayed M
- Al-Habib A
- Al-Habsi R
- Al-Ishaq Z
- Al-Khayal K
- Al-Masri M
- Al-Mohammad A
- Al-mukhtar A
- Al-Najjar H
- Al-omishy H
- Al-Sarireh B
- Al-Tamimi Y
- Alaa S
- AlAamer O
- Aladeojebi A
- Alakaloko F
- Alam F
- Alam N
- Alam R
- Alameer E
- Alamri A
- Alamri A
- Alanbuki A
- Alatar A
- Alawneh F
- Alazawi D
- Albertsmeier M
- Albertsmeiers M
- Albi Martin B
- Alburakan A
- Alcaide Matas F
- Alconchel F
- Aldayri Z
- Aldecoa Ansorregui I
- Alderson D
- Aldokali N
- Aleksic L
- Alemanno G
- Alexoudi V
- Alfaro-Goldaracena A
- Alfieri S
- Alga A
- Alghamdi M
- Alhalal H
- Alhamed A
- Alharthi M
- Alharthi R
- Alhassan B
- Alhassan N
- Alhefdhi A
- Ali AK
- Ali M
- Ali MF
- Ali S
- Aliyeva Z
- Aljanadi F
- Aljiffry M
- Alkadeeki GZ
- Alkarak S
- Allemand C
- Allison J
- Almalik O
- Almasri M
- Almeciga A
- Almeida A
- Almeida AC
- Almeida JI
- Almgla N
- Almond M
- Almond M
- Alnumani T
- Alobeed O
- Alomair A
- Alonso de la Fuente N
- Alonso Poza A
- Alonso-Lamberti L
- Alotaibi N
- Alqannas M
- Alresaini F
- Alriyees L
- Alsaif A
- Alsaif F
- Alsalamah R
- Alsaraireh O
- Alselaim N
- Alser O
- Alshaar M
- Alshahrani M
- Alshammari S
- Alshareea E
- Alsharif F
- Alshaygy I
- Alshryda S
- Alsobhi S
- Althobaiti W
- Altintoprak F
- Alurralde C
- Alvarez E
- Alvarez MR
- Alyami M
- Alzamanan M
- Amaral MJ
- Ameerally P
- Amira G
- Amonkar S
- Amorim E
- Ampollini L
- Amrani L
- Anania G
- Anastasi A
- Anchuelo Latorre J
- Andaleeb U
- Andaya V
- Andrade AK
- Andrade R
- Andrijasevic S
- Aneke IA
- Ang K
- Angele M
- Angelo M
- Angelou D
- Angelou K
- Annamalai S
- Annessi V
- Ansarin M
- Anthoulakis C
- Antic A
- Antic S
- Antonakis P
- Antoniades K
- Antonopoulou MI
- Anula R
- Anwar S
- Anzak A
- Aoun S
- Aprile A
- Aquila F
- Aragon Achig EJ
- Aremu I
- Aremu M
- Aresu G
- Aribi N
- Aribi S
- Arican C
- Arif T
- Arigoni M
- Arikan AE
- Arkadopoulos N
- Arkha Y
- Armao T
- Armatura G
- Arminio A
- Arnaud AP
- Arrangoiz R
- Arrowsmith L
- Artigues E
- Arulanantham A
- Asaad P
- Ascensao J
- Ashcroft J
- Ashmore C
- Ashoush F
- ASiT AS
- Askari A
- Asqalan A
- Assaf M
- Assalaarachchi H
- Asti E
- Astreidis I
- Athanasakis E
- Athanasiou A
- Athayde Nemesio R
- Atherton R
- Athwal R
- Atici DS
- Atta R
- Attia D
- Augestad KM
- Australasian T
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- Publication venue
- Br J Surg
- Publication date
- 11/11/2020
- Field of study
BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; P = 0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas