Performance of an ablator for Space Shuttle inorbit repair in an arc-plasma airstream

An ablator patch material performed well in an arc plasma environment simulating nominal Earth entry conditions for the Space Shuttle. Ablation tests using vacuum molded cones provided data to optimize the formulation of a two part polymer system for application under space conditions. The blunt cones were made using a Teflon mold and a state of the art caulking gun. Char stability of formulations with various amounts of catalyst and diluent were investigated. The char was found to be unstable in formulations with low amounts of catalyst and high amounts of diluent. The best polymer system determined by these tests was evaluated using a half tile patch in a multiple High Temperature Reusable surface Insulation tile model. It was demonstrated that this ablator could be applied in a space environment using a state of the art caulking gun, would maintain the outer mold line of the thermal protection system during entry, and would keep the bond line temperature at the aluminum tile interface below the design limit

Informality, Gender Employment Gap, and COVID-19 in Mexico: Identifying Persistence and Dynamic Structural Effects

The objective is to analyze the impact of the COVID-19 pandemic on the dynamics of the Mexican labor market (formal-informal employment) by gender. It is built consistent micro-founded time-series from 1987:Q1 to 2019:Q4 using the Mexican urban employment surveys and estimate a VAR model linking aggregate production and each market segment. Our results suggest significant adverse effects on formal employment resulting from the COVID-19 pandemic, with lengthy job recovery for females and males. The informal sector in both genders presents a lower forecasted response to the initial production shock but substantial observed employment losses, potentially linked to structural changes in the market. In the COVID-19 crisis, the informal sector is not a substitute for formal employment losses. The complexity of this crisis suggests crafting policies to improve the easiness of the market to enhance formal job recovery while promoting gender equality. Our main contribution is to estimate the diverse employment losses by segments and a critical structural change in the labor market dynamics resulting from the COVID-19 pandemic focusing on urban employment.Informalidad, brecha de género en el empleo y COVID-19 en México: identificando la persistencia y los efectos estructurales dinámicosEl objetivo es analizar el impacto de la pandemia del COVID-19 en la dinámica del mercado laboral mexicano (empleo formal-informal) por género. Se construyen series de tiempo microfundamentales consistentes desde 1987:Q1 hasta 2019:Q4 utilizando las encuestas de empleo urbanas mexicanas, y se estima un modelo VAR que vincula la producción agregada y cada segmento del mercado. Nuestros resultados sugieren que hay efectos adversos significativos en el empleo formal como resultado de la pandemia del COVID-19, con una larga recuperación del empleo para las mujeres y los hombres. El sector informal, en ambos sexos, presenta una respuesta pronosticada menor al choque de producción inicial, pero pérdidas sustanciales de empleo observadas, potencialmente vinculadas a cambios estructurales en el mercado. En la crisis de COVID-19, el sector informal no es un sustituto de las pérdidas de empleo formal. La complejidad de esta crisis sugiere la elaboración de políticas que mejoren la facilidad del mercado para potenciar la recuperación del empleo formal al tiempo que se promueve la igualdad de género. Nuestra principal contribución es estimar las diversas pérdidas de empleo por segmentos y un cambio estructural crítico en la dinámica del mercado laboral resultante de la pandemia de COVID-19, centrando el análisis en el empleo urbano

Variations to the cryptographics algorithms AES and TWOFISH

The cryptographic algorithms AES and Twofish guarantee a high diffusion by the use of fixed 4x4 MDS matrices. In this article variations to the algorithms AES and Twofish are made. They allow that the process of cipher - decipher come true with MDS matrices selected randomly from the set of all MDS matrices with the use of proposed algorithm. A new key schedule with a high diffusion is designed for the algorithm AES. Besides proposed algorithm generate new S - box that depends of the key

Disciplina positiva para el fortalecimiento de la inteligencia emocional en los ni?os de transici?n B de la instituci?n educativa Instituto Tebaida

80 p. Recurso Electr?nicoEste proyecto de investigaci?n se enfoc? especialmente en la implementaci?n de un plan de aula basado en la disciplina positiva para el fortalecimiento de la inteligencia emocional basado en la disciplina positiva de los ni?os de transici?n B de la Instituci?n educativa Instituto Tebaida, de La Tebaida Quind?o fue dirigida a una poblaci?n de 28 ni?os. Cuyo objetivo principal fue fortalecer la Inteligencia Emocional a trav?s de un plan de aula basado en la disciplina positiva, lo que impuls? a la realizaci?n de este plan de intervenci?n fue observar que algunos ni?os presentaban dificultades para seguir las instrucciones, estos ni?os no trabajan casi en equipo con los otros compa?eros, tienden a ser bruscos y agresivos o con un vocabulario poco cortes, contestan antes de que la maestra termine de preguntar, cuando hacen actividades en clase con reglas no las cumplen ni esperan el turno, interrumpiendo constantemente, no miden las consecuencias da?ando los juguetes o herramientas de trabajo del aula de clase, generando indisciplina y distrayendo a los otros ni?os que est?n inmersos en las actividades. Por lo tanto se vio la necesidad de realizar actividades que fortalecieran la inteligencia emocional, adem?s, se abordaron investigaciones sobre disciplina positiva, inteligencia interpersonal e intrapersonal, donde se encontraron referentes te?ricos, que fueron la base principal para la elaboraci?n de esta investigaci?n. Palabras clave: Disciplina positiva, inteligencia emocional, metodolog?a.This research project is especially focused on the implementation of a plan of classroom based on positive discipline for strengthening emotional intelligence based on positive discipline of children transition B of the Educational Institution Institute Tebaida La Tebaida Quind?o was addressed to a population of 28 children. Whose main objective was to strengthen Emotional Intelligence through a plan classroom based on positive discipline, which prompted the realization of this plan of action was observed that some children had difficulty following instructions, these children do not work nearly team with other colleagues, tend to be abrupt and aggressive or with a little vocabulary cuts, answer before the teacher finished asking, when do activities in class rules do not comply or expect the turn, constantly interrupting, no measure damaging consequences toys or tools of the classroom, creating indiscipline and distracting the other children who are involved in activities. So was the need for activities that strengthen emotional intelligence, further research on positive discipline, interpersonal and intrapersonal intelligence, where theoretical framework, which were the main basis for the development of this research were found addressed. Keywords: Positive Discipline, emotional intelligence, methodology

Structural and Mössbauer study of (Sb0.70Te0.30)100-x Snx alloys with x = 0, 2.5, 5.0 and 7.5

(Sb 0.70 Te 0.30 ) 100-x Sn x alloys (with x = 0, 2.5, 5.0 and 7.5 at. %)have been synthesized and characterized in order to determine the crystalline structure and properties of materials obtained upon solidification and to extract information about the location of the Sn atom in the Sb-Te matrix. Powder X-ray diffraction (XRD)has been used to determine the crystalline structure, whereas Mössbauer spectroscopy has been utilized to determine the localization and the local structure of the Sn atom in the Sb-Te matrix through the hyperfine interactions of the 119 Sn probe with its environment. We found that Sb 70 Te 30 crystallizes in a trigonal structure belonging to P-3m1 space group, while the doping with Sn leads to structural distortions of the unit cell that can be described, for all the Sn concentrations, with the C2/m space group. The hyperfine parameters indicate that tin behaves as Sn(II)and has a slightly distorted environment. Finally, in order to extract all the information that the experimental results contain and to determine the preferential site occupied by the Sn impurities in the Sb-Te matrix, we have performed ab-initio calculations within the framework of the Density Functional Theory. The theoretical results enable us to determine the structural and electronic ground state of (Sb 0.70 Te 0.30 ) 100-x Sn x compounds and to confirm that Sn atoms substitute Sb atoms in the Sb-Te host.Fil: Rocca, Javier Alejandro. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long". Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; ArgentinaFil: Bilovol, Vitaliy. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long". Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; ArgentinaFil: Errandonea, Alfredo Mario. Universidad de Valencia; EspañaFil: Gil Rebaza, Arles Víctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; ArgentinaFil: Mudarra Navarro, Azucena Marisol. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; ArgentinaFil: Medina Chanduvi, Hugo Harold. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; ArgentinaFil: Errico, Leonardo Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; ArgentinaFil: Arcondo, B.. Universidad Nacional del Noroeste de la Provincia de Buenos Aires; ArgentinaFil: Fontana, Marcelo. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long". Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; ArgentinaFil: Rodríguez Cuellar, O.. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long". Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentina. Universidad de Buenos Aires; ArgentinaFil: Ureña, María Andrea. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long". Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentin

Borrelia burgdorferi Infection in Biglycan Knockout Mice

Background: Borrelia burgdorferi sensu lato spirochetes (Borrelia) causing Lyme borreliosis are able to disseminate from the initial entry site to distant organs in the host. Outer-surface adhesins are crucial in the bacterial dissemination and adhesion to various tissues. Two well-characterized Borrelia adhesins, decorin-binding proteins A and B, have been shown to bind to 2 host receptors, decorin and biglycan. However, the role of biglycan in Borrelia infection has not been characterized in vivo.Methods: We infected biglycan knockout (KO) and wild-type (WT) C3H mice with strains representing 3 Borrelia genospecies, Borrelia burgdorferi sensu stricto, Borrelia garinii, and Borrelia afzelii. The infection was monitored by measuring joint swelling, Borrelia culture, polymerase chain reaction analysis, and serologic analysis. The host immune responses were analyzed by histological scoring of the inflammation in tissues and by cytokine profiling.Results: B. burgdorferi sensu stricto and B. garinii established long-term infection in mice of both genotypes, while B. afzelii failed to disseminate in KO mice. Further, the B. burgdorferi sensu stricto–infected KO mice had persistent inflammation in the joints.Conclusions: The dissemination and tissue colonization of Borrelia and the inflammatory response of the host differ in a mouse biglycan expression– and Borrelia genospecies–dependent manner.</p

Actual problems of applying clinical recommendations for arterial hypertension in the outpatient basis

The article presents the data obtained as the result of the outpatient medical record study. We reviewed medical records from patients with arterial hypertension, analyzed the types and volume of health care services that were provided to the hypertension patients at ambulatory care services, and assessed its compliance with clinical guidelines.В статье изложены данные, полученные в результате анализа амбулаторных карт пациентов с артериальной гипертензией. Проанализированы характер и объем медицинской помощи больным с гипертонической болезнью на амбулаторном этапе и их соответствие клиническим рекомендациям

Targeted Sequencing of Candidate Regions Associated with Sagittal and Metopic Nonsyndromic Craniosynostosis

Craniosynostosis (CS) is a major birth defect in which one or more skull sutures fuse prematurely. We previously performed a genome-wide association study (GWAS) for sagittal nonsyndromic CS (sNCS), identifying associations downstream from BMP2 on 20p12.3 and intronic to BBS9 on 7p14.3; analyses of imputed variants in DLG1 on 3q29 were also genome-wide significant. We followed this work with a GWAS for metopic non-syndromic NCS (mNCS), discovering a significant association intronic to BMP7 on 20q13.31. In the current study, we sequenced the associated regions on 3q29, 7p14.3, and 20p12.3, including two candidate genes (BMP2 and BMPER) near some of these regions in 83 sNCS child-parent trios, and sequenced regions on 7p14.3 and 20q13.2-q13.32 in 80 mNCS child-parent trios. These child-parent trios were selected from the original GWAS co-horts if the probands carried at least one copy of the top associated GWAS variant (rs1884302 C allele for sNCS; rs6127972 T allele for mNCS). Many of the variants sequenced in these targeted regions are strongly predicted to be within binding sites for transcription factors involved in crani-ofacial development or bone morphogenesis. Variants enriched in more than one trio and predicted to be damaging to gene function are prioritized for functional studies