1877-08-09

The Old Commonwealth was a weekly newspaper published in Harrisonburg, Va., between 1865 and 1884

Dielectric Properties of Healthy Ex-Vivo Ovine Lung Tissue at Microwave Frequencies

Knowledge of dielectric properties of lung tissue is fundamental for the improvement of lung disease diagnostics and therapeutic solutions (e.g. microwave imaging and microwave thermal ablation treatment). Although lung disease rates are increasing, lung tissue remains one of the least characterized tissues due to its heterogeneity, variability in air content, and handling difficulties. In this work, dielectric properties of ex-vivo ovine lung tissue samples were measured in the frequency range 500 MHz – 8 GHz, together with measurements of sample density (air content). Different Cole-Cole models were applied to the measured dielectric properties values. The best fitting model was chosen, and results were compared with available literature. Furthermore, the dielectric property measurements were correlated with the air content of the samples. Updated Cole-Cole models for lung tissue of different density is provided in the 500 MHz – 8 GHz range. The existence of air content threshold in lung is shown. Below this limit, the properties begin to change drastically with the change in densit

Effects of standard coagulant agents on the dielectric properties of fresh human blood

In this paper, the effects of coagulation and temperature on the dielectric properties of human blood are investigated over the frequency range of 400 MHz-20 GHz using freshly extracted blood samples. The dielectric properties are measured using blood in four different sample collection tubes (bottles): one containing pure whole blood, two containing different anticoagulant agents, and one containing clot activator and serum separator. The collected data indicates that additive agents can have a significant impact on the measured dielectric properties of blood, both immediately after the sample is taken, and over longer time periods. This is an important finding as it suggests that measurements of blood properties conducted on sample repositories, or tissue banks, may not be representative of natural blood properties. Further, the results demonstrate that the dielectric properties of normal blood vary over time due to coagulation. Different clotting rates lead to dielectric properties of female and male blood samples that vary distinctly over time. The results also show that the relative permittivity of the anti-coagulated blood decreases with increasing temperature, up to the cross-over point around 10 GHz where the trend reverses.peer-reviewe

Sedative load and frailty among community-dwelling population aged ≥65 years

OBJECTIVE: To explore the association between use of sedative drugs and frailty. DESIGN: Cross-sectional study. SETTING: First wave of The Irish Longitudinal Study on Ageing (TILDA), a nationally representative cohort of the community-dwelling population aged 50 years or older in Ireland. PARTICIPANTS: Participants were 1642 men and 1804 women aged 65 years or older. MEASUREMENTS: Regular use of sedative drugs determined according to the sedative load (SL) model, frailty phenotype status, and frailty deficit index (FI) score assessed using validated, established protocols. RESULTS: Overall, 19% of the participants took sedative drugs, most frequently hypnotics and antidepressants. Sedative drug use was at 46% for frail, 23% for prefrail, and 9% for nonfrail participants. After adjustment for covariates, SL was positively associated with being prefrail (odds ratio [OR] 1.27; 95% confidence interval [CI] 1.11-1.46) and frail (OR 1.30; 95% CI 1.02-1.64). Advancing age but not sex remained significant (P < .001). After adjustment for covariates, the association between SL and the FI was also significant at P ≤ .001 (β = 1.77; 95% CI 1.13-2.42). CONCLUSION: Higher SL was positively associated with phenotype frailty and the FI. This suggests that careful consideration must be given when prescribing sedatives to frail older adults, who are most vulnerable to adverse drug reactions and adverse health outcomes

Dielectric properties of fresh human blood

The dielectric properties of blood are extremely important for electromagnetic medical applications such as imaging, hyperthermia and ablation. The aim of this paper is to investigate the dielectric properties of human blood and examine the effects of anti-coagulant agents over a broad frequency range. The measurements were performed using freshly extracted human blood samples with and without the added agents. The measurements were performed within 20 mins after extracting the blood sample. The obtained results demonstrate a significant variation between the dielectric properties of blood with and without anti-coagulant agents. The difference is larger in conductivity than in relative permittivity. The results also demonstrate clear variation in the dielectric properties of female and male blood samples. The findings in this paper suggest that measurements conducted on blood samples with the added agents may not represent the natural in-vivo and inter-patient variations in blood properties. In order to have an accurate representation of in-vivo blood dielectric properties, all factors should be considered carefully.peer-reviewe

Properties of the giant HII regions and bar in the nearby spiral galaxy NGC5430

In order to better understand the impact of the bar on the evolution of spiral galaxies, we measure the properties of giant HII regions and the bar in the SB(s)b galaxy NGC5430. We use two complementary data sets, both obtained at the Observatoire du Mont-M\'egantic: a hyperspectral data cube from the imaging Fourier transform spectrograph SpIOMM, and high-resolution spectra across the bar from a long-slit spectrograph. We flux-calibrate SpIOMM spectra for the first time, and produce H{\alpha} and [NII]{\lambda}6584\r{A} intensity maps from which we identify 51 giant HII regions in the spiral arms and bar. We evaluate the type of activity, the oxygen abundance and the age of the young populations contained in these giant HII regions and in the bar. Thus, we confirm that NGC5430 does not harbour a strong AGN, and that its Wolf-Rayet knot shows a pure HII region nature. We find no variation in abundance or age between the bar and spiral arms, nor as a function of galactocentric radius. These results are consistent with the hypothesis that a chemical mixing mechanism is at work in the galaxy's disc to flatten the oxygen abundance gradient. Using the starburst99 model, we estimate the ages of the young populations, and again find no variations in age between the bar and the arms or as a function of radius. Instead, we find evidence for two galaxy-wide waves of star formation, about 7.1 Myr and 10.5 Myr ago. While the bar in NGC5430 is an obvious candidate to trigger these two episodes, it is not clear how the bar could induce widespread star formation on such a short time-scale.Comment: 14 pages, 9 figures, 3 tables, accepted for publication in MNRA

Can ground-based assessments of forest biodiversity reflect the biological condition of canopy assemblages?

© 2015 . Biological assessments of forest systems often involve a single ground-invertebrate sampling method that may ignore the biological component of the non-sampled canopy. Pitfall trapping for ground-active arthropods is a widely implemented technique for biological assessment in forested and open habitats. Although much evidence highlights the biases of pitfall trapping, this evidence typically comes from open-habitat crop and grassland systems. In forest systems where much of the biodiversity is found within the above-ground structure, management recommendations based solely on ground sampling may not represent the diversity within the three dimensional forest habitat. We provide evidence from combined ground and canopy sampling of three major forest types within the study region. We use canopy insecticide fogging to compare with more traditional ground-based pitfall trapping, and use spiders as a comparative species-rich biota that is able to colonise most terrestrial habitats and is strongly affected by changes in environmental condition.We identified 3933 spiders from 109 species from the 18 forest patches sampled. Both types of sampling defined differences in community composition between forest types in a similar manner; hence, either method could be used to evaluate differences or test management regimes in well-replicated experiments of forest type. However, the association in community composition between ground and canopy assemblages at the individual site-based level was weak; we found low correlation between the two data sets indicating that surrogacy between methods was not supported at this level. Furthermore, disparities in spider habitat association, body size, hunting guild and vertical stratification of spider families indicates that where detailed species and family-based information is required, or if inventorying is necessary, then multiple targeted surveys are essential