Forging the compact of church and state in the development of Catholic education in late nineteenth-century Scotland

As post-devolution Scotland passes the milestone of a third Scottish parliamentary election, the question of state-supported Catholic education, and the peculiar nature of the 1918 UK legislation that underpins it, is once again the subject of intense scrutiny. Emboldened by devolution and fuelled by a wave of progressive UK and European law concerned with issues of equality and diversity, opponents of separate Catholic schools have renewed their demands for the provisions of the 1918 Act to be reviewed or, indeed, abolished. With the ninetieth anniversary of the passage of the Act approaching, influential commentators from across the political spectrum have argued that its principal terms reflect the social and religious controversies of a distant era, increasingly incongruent with the inclusive culture of a multiethnic and mostly secular twenty-first century Scotland.1 The character and scale of the objections currently levelled at the continued existence of Catholic schools in Scotland suggests that reconsideration of the transactions between Church and State that led to the signing of the 1918 Act is perhaps overdue – especially as a realignment of the relationship between the two forces seems currently to be well advanced

Behind bars: the truth about drugs in prisons

The consumption and dealing of drugs has long been a criminal offence, so how are drugs finding their way into prisons that are meant to be secure places of law enforcement? To be able to confront the problem, an in-depth understanding is needed on the current situation of drugs within prisons. This review focuses on three aspects, firstly looking at the main ways drugs are trafficked into prisons, secondly looking at the issues linked to the use of drugs within prisons and finally evaluating what is being done to try to tackle the problem. Drugs find their way into prisons in numerous ways, which causes problems for the prison system. Prison officials need to be able to keep up with the creative and inventive ways inmates are developing to traffic drugs into prisons. A third of prisoners in England and Wales claimed it was easier to get hold of drugs in prison than it was outside. This undermines prison security and creates problems with violence together being linked with reoffending. Two in five prisoners in England and Wales are known to commit offences in order to get funds to purchase drugs. Health risks are created by inmates sharing syringes, leading to the transmission of infectious diseases. This in turn causes the costs of treatments and detection methods to spiral out of control. Governments are constantly trying to proactively find ways to tackle drugs in prison; these include the use of sniffer dogs and employing more thorough searches by staff. But more needs to be done to eradicate drugs completely

DNA and fingerprint recovery from an arson scene

The different methods of both DNA and fingerprint recovery from arson scenes are analysed within this literature. Arson is often used as a mode of concealment due to the wide misconception that fire destroys fundamental evidence. Advances in recent research and technologies have meant that techniques have been developed to further aid and enhance the recovery of evidence that has been exposed to the extreme conditions of a fire. In the forefront of all fire investigations where evidence recovery is paramount, the stages of the fire should be taken into consideration and pre-eminent soot removal techniques carried out in order to expose and visualise any evidence present. Although evaluation of current literature demonstrates that exceptional results from both fingerprints and DNA exposed to fire can be obtained, through different enhancement techniques, further research and developments are required in order to ensure these essential developments are standardised and mandatory to all arson scenes

The Emerging Role of Epigenetic Modifiers in Repair of DNA Damage Associated with Chronic Inflammatory Diseases

At sites of chronic inflammation epithelial cells are exposed to high levels of reactive oxygen species (ROS), which can contribute to the initiation and development of many different human cancers. Aberrant epigenetic alterations that cause transcriptional silencing of tumor suppressor genes are also implicated in many diseases associated with inflammation, including cancer. However, it is not clear how altered epigenetic gene silencing is initiated during chronic inflammation. The high level of ROS at sites of inflammation is known to induce oxidative DNA damage in surrounding epithelial cells. Furthermore, DNA damage is known to trigger several responses, including recruitment of DNA repair proteins, transcriptional repression, chromatin modifications and other cell signaling events. Recruitment of epigenetic modifiers to chromatin in response to DNA damage results in transient covalent modifications to chromatin such as histone ubiquitination, acetylation and methylation and DNA methylation. DNA damage also alters non-coding RNA expression. All of these alterations have the potential to alter gene expression at sites of damage. Typically, these modifications and gene transcription are restored back to normal once the repair of the DNA damage is completed. However, chronic inflammation may induce sustained DNA damage and DNA damage responses that result in these transient covalent chromatin modifications becoming mitotically stable epigenetic alterations. Understanding how epigenetic alterations are initiated during chronic inflammation will allow us to develop pharmaceutical strategies to prevent or treat chronic inflammation-induced cancer. This review will focus on types of DNA damage and epigenetic alterations associated with chronic inflammatory diseases, the types of DNA damage and transient covalent chromatin modifications induced by inflammation and oxidative DNA damage and how these modifications may result in epigenetic alterations

Evaluation of elicitation methods to quantify Bayes linear models

The Bayes linear methodology allows decision makers to express their subjective beliefs and adjust these beliefs as observations are made. It is similar in spirit to probabilistic Bayesian approaches, but differs as it uses expectation as its primitive. While substantial work has been carried out in Bayes linear analysis, both in terms of theory development and application, there is little published material on the elicitation of structured expert judgement to quantify models. This paper investigates different methods that could be used by analysts when creating an elicitation process. The theoretical underpinnings of the elicitation methods developed are explored and an evaluation of their use is presented. This work was motivated by, and is a precursor to, an industrial application of Bayes linear modelling of the reliability of defence systems. An illustrative example demonstrates how the methods can be used in practice

Key actors in driving behavioural change in relation to on-farm biosecurity; a Northern Ireland perspective

Background: Agriculture and farming are valued contributors to local economy in Northern Ireland (NI). There is limited knowledge about farmers’ behaviours and attitudes towards disease biosecurity measures. As part of a larger project, a scenario-based workshop with key stakeholders was organised by the Agri-Food and Biosciences Institute (AFBI)-NI in December 2015. Results: A total of 22 participants belonging to 12 different institutions took part in the workshop. Participants were presented with an overview of previously conducted biosecurity research in NI and England. In small groups, participants were subsequently asked to discuss and give their opinions about a series of questions across four key areas in a semi-structured approach with an external facilitator. The key areas were 1- disease risk perception at the farm level; 2-perceived barriers to implementing on farm biosecurity measures; 3- avenues to successful behaviour change and 4-key industry responsibilities and roles. The discussion showed that training in biosecurity for farmers is important and necessary. Training was recommended to be provided by veterinary surgeons, preferably via a face-to-face format. The discussion addressing disease disclosure proved particularly challenging between those who were prospective buyers of cattle, and those who sold cattle. Conclusions: This workshop provided a unique and invaluable insight into key issues regarding farm level biosecurity activities. From a policy perspective, delivering improved on-farm biosecurity must be addressed via a multidisciplinary approach. This can only be achieved with active involvement, commitment and support of a number of key industry and government stakeholders

Managing structural uncertainty in health economic decision models: a discrepancy approach

Healthcare resource allocation decisions are commonly informed by computer model predictions of population mean costs and health effects. It is common to quantify the uncertainty in the prediction due to uncertain model inputs, but methods for quantifying uncertainty due to inadequacies in model structure are less well developed. We introduce an example of a model that aims to predict the costs and health effects of a physical activity promoting intervention. Our goal is to develop a framework in which we can manage our uncertainty about the costs and health effects due to deficiencies in the model structure. We describe the concept of `model discrepancy': the difference between the model evaluated at its true inputs, and the true costs and health effects. We then propose a method for quantifying discrepancy based on decomposing the cost-effectiveness model into a series of sub-functions, and considering potential error at each sub-function. We use a variance based sensitivity analysis to locate important sources of discrepancy within the model in order to guide model refinement. The resulting improved model is judged to contain less structural error, and the distribution on the model output better reflects our true uncertainty about the costs and effects of the intervention

First Measurements with NeXtRAD, a Polarimetric X/L Band Radar Network

NeXtRAD is a fully polarimetric, X/L Band radar network. It is a development of the older NetRAD system and builds on the experience gained with extensive deployments of NetRAD for sea clutter and target measurements. In this paper we will report on the first measurements with NeXtRAD, looking primarily at sea clutter and some targets, as well as early attempts at calibration using corner reflectors, and an assessment of the polarimetric response of the system. We also highlight innovations allowing for efficient data manipulation post measurement campaigns, as well as the plans for the coming years with this system

Governance barriers to sustainable energy transitions – Assessing Ireland's capacity towards marine energy futures

Marine energies (ME), including offshore hydcrocarbons along with marine renewable energies (MRE), such as offshore wind, wave and tidal energy, are increasingly important in the future energy mix of many nations. We observe that ME governance is complex, as development offshore involves engagement and may often result in conflict. This paper examines the Irish case, where offshore gas and oil remain relatively undeveloped, and yet have provoked extensive controversy. Moreover, Ireland exhibits very ambitious plans for MRE developments. Against a background, where ME development seems to have stalled, the objective of the paper is to analyse the Irish governance setup and its capacity to deliver ME and whether the current system is equipped to enable transition to MREs. Current governance systems lack efficacy in terms of policy integration and enforcement, government oversight, and public trust due to past failures. Although, management approaches have been developed to address some of the barriers, domains such as policy/regulation, industry development and public engagement are disconnected. Results: presented may not simply be generalised, as each country context is different. An analysis of examples with similar issues must focus on studying the context of the governance setup and balances of power across domains