Catálogo de las umbeliferas "apiaceae" malacitanas (Málaga, España)

Se ha realizado un catálogo de las umbelíferas (Apiaceae) presentes en la provincia de Málaga (Andalucía, España). De cada uno de los 103 táxones citados (44 géneros) indicamos su localidad, referencia bibliográfica y pliegos de herbarios. Así mismo se realiza un análisis del comportamiento ecológico de cada uno de ellos, de su ubicación biogeográfica en la provincia y de la diversidad taxonómica

Catálogo de las umbelíferas (apiaceae) malacitanas (Málaga, España)

A chorological review of the Apiaceue has been carried from Málaga (Andalucía, España). 103 taxons are cited (44 genus); bibliography and herbarium material are reported.Se ha realizado un catálogo de las umbelíferas (Apiaceae) presentes en la provincia de Málaga (Andalucía, España). De cada uno de los 103 táxones citados (44 géneros) indicamos su localidad, referencia bibliográfica y pliegos de herbarios. Así mismo se realiza un análisis del comportamiento ecológico de cada uno de ellos, de su ubicación biogeografica en la provincia y de la diversidad taxonómica

Proceso de afrontamiento y adaptación del personal de salud en un Hospital Rural bajo el modelo de Callista Roy

Introduction: Health personnel perceive a diversity of stimuli daily as they develop in their environment, these can be used in benefit or generating complications, this makes the individual become aware and make use of coping as a disposition to resolve or cope with changes, causing reactions and behaviors aimed at achieving adaptation, this phenomenon is of interest because it can help to better understand the dynamics in which nursing and medicine develop professionally. Objective: To determine the characteristics of the coping and adaptation processes in the health personnel of a rural hospital. Methodology: quantitative, combined, non-experimental, cross-sectional and correlational research, applying Callista Roy's Coping and Adaptation Process Measurement Scale. Results: Most of the population is female (62.7%), with a mean age of 36.89 years (SD: 10.28) and a professional seniority of 9.15 years (MV: 33), highlighting the domains of knowing and relating (very high ability of 52.0%) and alertness process (high ability of 62.7%). Conclusion: Health personnel have the tools to cope with the manifestations and modifications present in their environment, overcoming difficulties and characterizing them as beings with great strength.Introducción: El personal de salud percibe una diversidad de estímulos diariamente al desarrollarse en su entorno, estos pueden usarse en beneficio o generando complicaciones, esto hace que el individuo tome consciencia y haga uso del afrontamiento como una disposición para resolver o sobrellevar cambios, ocasionando reacciones y conductas encaminadas a lograr una adaptación, este fenómeno resulta de interés debido a que puede ayudar a comprender mejor la dinámica en que enfermería y medicina se desenvuelven profesionalmente. Objetivo: Determinar las características de los procesos de afrontamiento y adaptación en el personal de salud de un hospital rural. Metodología: investigación cuantitativa, combinada, no experimental, transversal y correlacional, aplicando la Escala de medición del proceso de afrontamiento y adaptación de Callista Roy. Resultados: La mayor parte de la población es femenina (62.7%), con una edad media de 36.89 años (DE: 10.28) y una antigüedad profesional de 9.15 años (VM: 33), destacando los dominios conocer y relacionar (capacidad muy alta de 52.0%) y proceso de alerta (capacidad alta de 62.7%). Conclusión: El personal de salud cuenta con herramientas para hacer frente a las manifestaciones y modificaciones presentes en su entorno, anteponiéndose a las dificultades y caracterizándolos como seres con una gran fortaleza

Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease

ObjectiveLow HDL-C (high-density lipoprotein cholesterol) is the most frequent dyslipidemia in Mexicans, but few studies have examined the underlying genetic basis. Our purpose was to identify genetic variants associated with HDL-C levels and cardiovascular risk in the Mexican population.Approach and resultsA genome-wide association studies for HDL-C levels in 2335 Mexicans, identified four loci associated with genome-wide significance: CETP, ABCA1, LIPC, and SIDT2. The SIDT2 missense Val636Ile variant was associated with HDL-C levels and was replicated in 3 independent cohorts (P=5.9×10−18 in the conjoint analysis). The SIDT2/Val636Ile variant is more frequent in Native American and derived populations than in other ethnic groups. This variant was also associated with increased ApoA1 and glycerophospholipid serum levels, decreased LDL-C (low-density lipoprotein cholesterol) and ApoB levels, and a lower risk of premature CAD. Because SIDT2 was previously identified as a protein involved in sterol transport, we tested whether the SIDT2/Ile636 protein affected this function using an in vitro site-directed mutagenesis approach. The SIDT2/Ile636 protein showed increased uptake of the cholesterol analog dehydroergosterol, suggesting this variant affects function. Finally, liver transcriptome data from humans and the Hybrid Mouse Diversity Panel are consistent with the involvement of SIDT2 in lipid and lipoprotein metabolism.ConclusionsThis is the first genome-wide association study for HDL-C levels seeking associations with coronary artery disease in the Mexican population. Our findings provide new insight into the genetic architecture of HDL-C and highlight SIDT2 as a new player in cholesterol and lipoprotein metabolism in humans

Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER)Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13-3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks