No-arbitrage condition and existence of equilibrium with dividends

In this paper we first give an elementary proof of existence of equilibrium with dividends in an economy with possibly satiated consumers.We then introduce a no-arbitrage condition and show that it is equivalent to the existence of equilibrium with dividends.equilibrium with dividends, economy with possibly satiated consumers, no-arbitrage condition

No-arbitrage condition and existence of equilibrium with dividends

International audienceIn this paper we first give an elementary proof of existence of equilibrium with dividends in an economy with possibly satiated consumers.We then introduce a no-arbitrage condition and show that it is equivalent to the existence of equilibrium with dividends

DEVELOPMENT AND EVALUATION OF ORAL SUSTAINED-RELEASE RANITIDINE DELIVERY SYSTEM BASED ON BACTERIAL NANOCELLULOSE MATERIAL PRODUCED BY KOMAGATAEIBACTER XYLINUS

Objective: The short biological half-life (2-3 h) and low bioavailability (50 %) of ranitidine (RAN) following oral administration favor the development of a controlled release system. This study was aimed to develop and in vitro evaluate oral sustained-release RAN delivery system based on the bacterial nanocellulose material (BNM) produced by Komagataeibacter xylinus (K. xylinus) from selected culture media. Methods: BNMs are biosynthesized by K. xylinus in the standard medium (SM) and coconut water (CW). RAN was loaded in BNMs by the absorption method. The structural and physicochemical properties of BNMs and BNMs-RAN were evaluated via swelling behavior, FTIR, and FESEM techniques. Moreover, the effect of BNMs on RAN release profile and release kinetics was analyzed and evaluated. Results: The amount of loaded RAN or entrapment efficacy for BNM-CW is higher than for BNM-SM. The BNM-SM-RAN and BNM-CW-RAN exhibited a decreased initial burst release system followed by a prolonged RAN release up to 24 h in relation to the commercial tablets containing RAN. The RAN release from these formulations was found higher in the SGF medium than that of in SIF medium. RAN released from these formulations was found to follow the Korsmeyer-Peppas model and diffusion sustained drug release mechanism. The sustained release of RAN from BNM-SM-RAN was slower than for RAN from BNM-CW-RAN, but the mechanism of sustained RAN release was the same. Conclusion: Oral sustained-release RAN delivery system based on BNMs was successfully prepared and evaluated for various in vitro parameters. The biopolymers like BNM-SM and BNM-CW could be utilized to develop oral sustained RAN release dosage form

chemical constituents from methanolic extract of Garcinia mackeaniana leaves and their antioxidant activity

A phytochemical investigation of the methanolic extract of Garcinia mackeaniana leaves led to the isolation, and determination of five secondary metabolites, including one benzophenone 4,3',4'-trihydroxy-2,6-dimethoxybenzophenone (1), two flavone C-glucosides vitexin (2) and its 2''-O-acetyl derivative (3), one biflavone amentoflavone (4), and one mono-phenol methyl protocatechuate (5). The chemical structures of these compounds were characterized by the NMR-spectroscopic method. These isolated compounds were isolated from G. mackeaniana species for the first time. Benzophenone derivative 1 has shown to be associated with a significant IC50 value of 14.97±0.8 µg/mL in the DPPH-antioxidant assay

Cytotoxic naphthoquinones from Diospyros fleuryana leaves

In the search for anti-cancer plants in Vietnam, the leaves of Diospyros fleuryana were selected for chemical investigation. Phytochemical analysis of the ethyl acetate (EtOAc) extract led to the isolation of two naphthoquinones isodiospyrin (1), and 8'-hydroxyisodiospyrin (2), and one isoflavone 7-O-methylbiochanin A (3). The chemical structures of isolated compounds were determined by 1D-NMR (1H, and 13C-NMR), 2D-NMR spectra (HSQC, and HMBC), and MS spectroscopy. Compound 3 was isolated from genus Diospyros for the first time. Regarding the strong IC50 values of 2.27, and 8.0 µM against KB, and Hep cell lines respectively, cytotoxic examination suggested that compound 2 is a promising agent in anti-cancer treatment.Â

Access to improved water, human capital and economic activity in Africa

This paper examines the correlation between access to improved water, human capital and economic activity in Africa. It shows that countries with higher access to improved water tend to have lower mortality rate than those with lower access to improved water even they have the same per capita GDP, population characteristics and other time-invariant characteristics. One percentage point increase in the proportion of population accessing improved water is associated with a decrease of 0.45 and 0.89 in the mortality rate (calculated as per mil). Although there is a very small correlation between the access to improved water and GDP per capita, there is a strong correlation between the access to improved water and poverty. Countries with higher proportion of population with access to improved water are more likely to have lower poverty

ĐẶC ĐIỂM BIẾN ĐỔI HÌNH THÁI ĐỊA HÌNH BÃI BIỂN NHA TRANG, KHÁNH HÒA

This paper has focused on analyzing morphological change features of Nha Trang Beach based on the comparison of different beach profiles which were measured from July 2008 to September 2016 corresponding to the Northeast and Southwest monsoons. Additionally, the sediment transport balance was estimated by the method of equity value curve. Studied results show that the beach profiles were accreted and eroded during Southwest and Northeast monsoons respectively, but due to the shortage of materials supply, the beach has the narrowing trend. In this paper, some effects of the existing works in Nha Trang Beach such as Vinpearl, Navy Port, and hydro-dams in upstream area of Cai river have been also analyzed for estimating sedimentary supply to beach segments.Bài báo phân tích đặc điểm biến đổi hình thái địa hình bãi biển Nha Trang trên cơ sở so sánh các trắc diện địa hình bãi biển, với số liệu đo đạc từ tháng 7/2008 đến tháng 9/2016, cụ thể vào các thời kỳ gió mùa Đông Bắc và gió mùa Tây Nam tại các vị trí cố định. Đồng thời, cán cân trầm tích được tính toán và phân tích bằng phương pháp đường cong đẳng giá trị. Kết quả cho thấy, bãi biển được bồi tụ vào mùa gió Tây Nam và bị xói lở vào mùa gió Đông Bắc. Tuy nhiên, do thiếu hụt bồi tích nên bãi biển có xu thế thu hẹp. Bài báo còn phân tích một số ảnh hưởng của các công trình hiện diện tại bãi biển Nha Trang, như cầu cảng Vinpearl, cảng Hải Quân và các đập chắn trên lưu vực sông Cái khi xét đến nguồn cung cấp vật liệu bồi tích

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke