404 research outputs found
Discrepancy Analysis Between Close-Range Photogrammetry And Terrestrial LiDAR
This study presents a comparison of building measurements performed on 3D models generated by two different approaches. In one approach, the models were produced via close-range photogrammetry. Such models are based on still-frame photographs that are, post-processed with commercially available photogrammetric software. In the second approach, 3D point-cloud models were generated via laser scanning. For this purpose, three case studies were conducted. The first was a simple one story structure, the second was a multi-story Maya ruin, and the third was an earth filled terrace. Several benchmarks within a closed traverse were established to serve as standard georeference points for all accuracy comparisons. Several physical target points were then marked on the exterior walls of the structure. They are referred here as reference wall points. The reference wall points were then measured with a total-station instrument. After photographs were taken and laser scanning of the structure performed, the coordinates of the reference wall points were also determined from the respective models. The coordinates were then compared with the ones obtained with the total-station instrument. Coordinates and distances from each procedure were compared to determine relative discrepancies and accuracies. The results of this study demonstrate that the close-range photogrammetry can provide accurate enough information to be used as an alternative for total stations or laser scanners when measuring buildings or other relatively small projects
Capabilities of the Skylab-A spectrometer (S191) for remote sensing of surface targets in the thermal-infrared spectral region
The effects of some of the factors which fundamentally limit the amount of information which can be deduced from spectrometer (S191) measurements, made from the orbital altitude of Skylab-A, of the thermal-infrared power radiated into space from typical surface targets are discussed. The particular significance of this spectral region is that the power radiated at night is comparable in intensity to that in daylight. Calculations were made which simulate the quality of spectrometer data that could be expected from spectral measurements made in space, of the thermal-infrared radiation emitted from typical rocks on the surface. The results indicate that the reststrahlen structure in these spectra is not distinctive enough to permit reliable identification of the rocks. This conclusion is confirmed by relevant data which have already been obtained from aircraft and spacecraft
Effective Communication And Creating Professional Learning Communities Is A Valuable Practice For Superintendents
As the chief executive officer, the superintendent must demonstrate high quality performance at every level in order to impact student achievement.  In order to be an effective superintendent, the individual must have knowledge and skills in educational leadership and be able to articulate information clearly and precisely about the school district, state and federal accountability systems, policy related to student achievement and personnel practices. The American Association of School Administrators states that the superintendent must know policy for collective bargaining processes for the state/local schools, school district policy and administrative regulations, district finances and budget matters, model the use of technology for instruction and management and should know the role of the Board of Education (AASA, 2011). Superintendents do not work alone, but work in collaboration with school personnel, leadership teams, broader communities and the Board of Education to ensure a productive school system.  The responsibilities of the superintendent are many. The superintendent has the task to supervise the general conduct of district schools, instructional curriculum, handle school district management affairs, hiring appropriate personnel and dismissal of personnel based on state policy through the human resources management office. For the local schools, the superintendent should seek ways to encourage the practices of learning communities within the school district for the purpose of working together to improve teaching instructional skills based on the needs of students and if effective will promote higher student learning (Stoll, 2006). This study will focus on skills and knowledge needed for superintendents, what parents want, value of data, strategic planning, effective communication, learning community practices of ethics and morals, technology as a resource, and the characteristics of high performing schools
Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure
Background: The development of effective therapies for acute liver failure (ALF) is limited by our knowledge of the pathophysiology of this condition, and the lack of suitable large animal models of acetaminophen toxicity. Our aim was to develop a reproducible invasively-monitored porcine model of acetaminophen-induced ALF.
Method: 35kg pigs were maintained under general anaesthesia and invasively monitored. Control pigs received a saline infusion, whereas ALF pigs received acetaminophen intravenously for 12 hours to maintain blood concentrations between 200-300 mg/l. Animals surviving 28 hours were euthanased.
Results: Cytochrome p450 levels in phenobarbital pre-treated animals were significantly higher than non pre-treated animals (300 vs 100 pmol/mg protein). Control pigs (n=4) survived 28-hour anaesthesia without incident. Of nine pigs that received acetaminophen, four survived 20 hours and two survived 28 hours. Injured animals developed hypotension (mean arterial pressure; 40.8+/-5.9 vs 59+/-2.0 mmHg), increased cardiac output (7.26+/-1.86 vs 3.30+/-0.40 l/min) and decreased systemic vascular resistance (8.48+/-2.75 vs 16.2+/-1.76 mPa/s/m3). Dyspnoea developed as liver injury progressed and the increased pulmonary vascular resistance (636+/-95 vs 301+/-26.9 mPa/s/m3) observed may reflect the development of respiratory distress syndrome. Liver damage was confirmed by deterioration in pH (7.23+/-0.05 vs 7.45+/-0.02) and prothrombin time (36+/-2 vs 8.9+/-0.3 seconds) compared with controls. Factor V and VII levels were reduced to 9.3 and 15.5% of starting values in injured animals. A marked increase in serum AST (471.5+/-210 vs 42+/-8.14) coincided with a marked reduction in serum albumin (11.5+/-1.71 vs 25+/-1 g/dL) in injured animals. Animals displayed evidence of renal impairment; mean creatinine levels 280.2+/-36.5 vs 131.6+/-9.33 mumol/l. Liver histology revealed evidence of severe centrilobular necrosis with coagulative necrosis. Marked renal tubular necrosis was also seen. Methaemoglobin levels did not rise >5%. Intracranial hypertension was not seen (ICP monitoring), but there was biochemical evidence of encephalopathy by the reduction of Fischer's ratio from 5.6 +/- 1.1 to 0.45 +/- 0.06.
Conclusion: We have developed a reproducible large animal model of acetaminophen-induced liver failure, which allows in-depth investigation of the pathophysiological basis of this condition. Furthermore, this represents an important large animal model for testing artificial liver support systems
Dissimilatory Fe(III) reduction controls on arsenic mobilisation: a combined biogeochemical and NanoSIMS imaging approach
This is the final version. Available on open access from Frontiers Media via the DOI in this recordMicrobial metabolism plays a key role in controlling the fate of toxic groundwater
contaminants such as arsenic. Dissimilatory metal reduction catalysed by subsurface bacteria
can facilitate the mobilisation of arsenic via the reductive dissolution of As(V)-bearing Fe(III)
mineral assemblages. The mobility of liberated As(V) can then be amplified via reduction to
the more soluble As(III) by As(V)-respiring bacteria. This investigation focused on the
reductive dissolution of As(V) sorbed onto Fe(III)-(oxyhydr)oxide by model Fe(III)- and
As(V)-reducing bacteria, to elucidate the mechanisms underpinning these processes at the
single cell scale. Axenic cultures of Shewanella sp. ANA-3 wild-type cells (able to respire both
Fe(III) and As(V)) were grown using C-labelled lactate on an arsenical Fe(III)-
(oxyhydr)oxide thin film, and after colonisation, the distribution of Fe and As in the solid phase
was assessed using nanoscale secondary ion mass spectrometry (NanoSIMS), complemented
with aqueous geochemistry analyses. Parallel experiments were conducted using an arrA
mutant, able to respire Fe(III) but not As(V). NanoSIMS imaging showed that most
metabolically active cells were not in direct contact with the Fe(III) mineral. Flavins were
released by both strains, suggesting that these cell-secreted electron shuttles mediated
extracellular Fe(III)-(oxyhydr)oxide reduction, but did not facilitate extracellular As(V)
reduction, demonstrated by the presence of flavins yet lack of As(III) in the supernatants of the
arrA deletion mutant strain. 3D reconstructions of NanoSIMS depth-profiled single cells
revealed that As and Fe were associated with the cell surface in the wild-type cells, whereas
for the arrA mutant only Fe was associated with the biomass. These data were consistent with
Shewanella sp. ANA-3 respiring As(V) in a multistep process; first the reductive dissolution
of the Fe(III) mineral released As(V), and once in solution, As(V) was respired by the cells to
As(III). As well as highlighting Fe(III) reduction as the primary release mechanism for arsenic,
our data also identified unexpected cellular As(III) retention mechanisms that require further
investigation.Mexican National Council for Science and Technology (CONACyT)Natural Environment Research Council (NERC
Prescription Drug Diversion: Predictors of Illicit Acquisition and Redistribution in Three U.S. Metropolitan Areas
Objective: Prescription drug diversion, the transfer of prescription drugs from lawful to unlawful channels for distribution or use, is a problem in the United States. Despite the pervasiveness of diversion, there are gaps in the literature regarding characteristics of individuals who participate in the illicit trade of prescription drugs. This study examines a range of predictors (e.g., demographics, prescription insurance coverage, perceived risk associated with prescription drug diversion) of membership in three distinct diverter groups: individuals who illicitly acquire prescription drugs, those who redistribute them, and those who engage in both behaviors.
Methods: Data were drawn from a cross-sectional Internet 763 AIMS Public Health Volume 2, Issue 4, 762-783. study (N = 846) of prescription drug use and diversion patterns in New York City, South Florida, and Washington, D.C.. Participants were classified into diversion categories based on their self-reported involvement in the trade of prescription drugs. Group differences in background characteristics of diverter groups were assessed by Chi-Square tests and followed up with multivariate logistic regressions.
Results: While individuals in all diversion groups were more likely to be younger and have a licit prescription for any of the assessed drugs in the past year than those who did not divert, individuals who both acquire and redistribute are more likely to live in New York City, not have prescription insurance coverage, and perceive fewer legal risks of prescription drug diversion.
Conclusion: Findings suggest that predictive characteristics vary according to diverter group
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