1,025 research outputs found

    Affective commitment and turnover intentions among healthcare professionals: the role of emotional exhaustion and disengagement

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    This paper utilises the conservation of resources theory to examine the mediating role played by disengagement in the relationships between emotional exhaustion, affective commitment and turnover intentions among healthcare professionals. Structural equation modelling was conducted on data obtained from 302 healthcare professionals in a major Australian cancer hospital. Our findings demonstrate that disengagement fully mediates the relationships between emotional exhaustion and both affective commitment and turnover intentions. Recommendations for future research are suggested and practical implications discussed. © 2013 Taylor & Francis

    Billion-atom Synchronous Parallel Kinetic Monte Carlo Simulations of Critical 3D Ising Systems

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    An extension of the synchronous parallel kinetic Monte Carlo (pkMC) algorithm developed by Martinez {\it et al} [{\it J.\ Comp.\ Phys.} {\bf 227} (2008) 3804] to discrete lattices is presented. The method solves the master equation synchronously by recourse to null events that keep all processors time clocks current in a global sense. Boundary conflicts are rigorously solved by adopting a chessboard decomposition into non-interacting sublattices. We find that the bias introduced by the spatial correlations attendant to the sublattice decomposition is within the standard deviation of the serial method, which confirms the statistical validity of the method. We have assessed the parallel efficiency of the method and find that our algorithm scales consistently with problem size and sublattice partition. We apply the method to the calculation of scale-dependent critical exponents in billion-atom 3D Ising systems, with very good agreement with state-of-the-art multispin simulations

    Self-Similar Scalar Field Collapse: Naked Singularities and Critical Behaviour

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    Homothetic scalar field collapse is considered in this article. By making a suitable choice of variables the equations are reduced to an autonomous system. Then using a combination of numerical and analytic techniques it is shown that there are two classes of solutions. The first consists of solutions with a non-singular origin in which the scalar field collapses and disperses again. There is a singularity at one point of these solutions, however it is not visible to observers at finite radius. The second class of solutions includes both black holes and naked singularities with a critical evolution (which is neither) interpolating between these two extremes. The properties of these solutions are discussed in detail. The paper also contains some speculation about the significance of self-similarity in recent numerical studies.Comment: 27 pages including 5 encapsulated postcript figures in separate compressed file, report NCL94-TP1

    Absorption and quasinormal modes of classical fields propagating on 3D and 4D de Sitter spacetime

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    We extensively study the exact solutions of the massless Dirac equation in 3D de Sitter spacetime that we published recently. Using the Newman-Penrose formalism, we find exact solutions of the equations of motion for the massless classical fields of spin s=1/2,1,2 and to the massive Dirac equation in 4D de Sitter metric. Employing these solutions, we analyze the absorption by the cosmological horizon and de Sitter quasinormal modes. We also comment on the results given by other authors.Comment: 31 page

    Mode coupling in the nonlinear response of black holes

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    We study the properties of the outgoing gravitational wave produced when a non-spinning black hole is excited by an ingoing gravitational wave. Simulations using a numerical code for solving Einstein's equations allow the study to be extended from the linearized approximation, where the system is treated as a perturbed Schwarzschild black hole, to the fully nonlinear regime. Several nonlinear features are found which bear importance to the data analysis of gravitational waves. When compared to the results obtained in the linearized approximation, we observe large phase shifts, a stronger than linear generation of gravitational wave output and considerable generation of radiation in polarization states which are not found in the linearized approximation. In terms of a spherical harmonic decomposition, the nonlinear properties of the harmonic amplitudes have simple scaling properties which offer an economical way to catalog the details of the waves produced in such black hole processes.Comment: 17 pages, 20 figures, abstract and introduction re-writte

    A multistate model of health transitions in older people: a secondary analysis of ASPREE clinical trial data

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    Background: Understanding the nature of transitions from a healthy state to chronic diseases and death is important for planning health-care system requirements and interventions. We aimed to quantify the trajectories of disease and disability in a population of healthy older people. Methods: We conducted a secondary analysis of data from the ASPREE trial, which was done in 50 sites in Australia and the USA and recruited community-dwelling, healthy individuals who were aged 70 years or older (≄65 years for Black and Hispanic people in the USA) between March 10, 2010, and Dec 24, 2014. Participants were followed up with annual face-to-face visits, biennial assessments of cognitive function, and biannual visits for physical function until death or June 12, 2017, whichever occurred first. We used multistate models to examine transitions from a healthy state to first intermediate disease events (ie, cancer events, stroke events, cardiac events, and physical disability or dementia) and, ultimately, to death. We also examined the effects of age and sex on transition rates using Cox proportional hazards regression models. Findings: 19 114 participants with a median age of 74·0 years (IQR 71·6–77·7) were included in our analyses. During a median follow-up of 4·7 years (IQR 3·6–5·7), 1933 (10·1%) of 19 114 participants had an incident cancer event, 487 (2·5%) had an incident cardiac event, 398 (2·1%) had an incident stroke event, 924 (4·8%) developed persistent physical disability or dementia, and 1052 (5·5%) died. 15 398 (80·6%) individuals did not have any of these events during follow-up. The highest proportion of deaths followed incident cancer (501 [47·6%] of 1052) and 129 (12·3%) participants transitioned from disability or dementia to death. Among 12 postulated transitions, transitions from the intermediate states to death had much higher rates than transitions from a healthy state to death. The progression rates to death were 158 events per 1000 person-years (95% CI 144–172) from cancer, 112 events per 1000 person-years (86–145) from stroke, 88 events per 1000 person-years (68–111) from cardiac disease, 69 events per 1000 person-years (58–82) from disability or dementia, and four events per 1000 person-years (4–5) from a healthy state. Age was significantly associated with an accelerated rate for most transitions. Male sex (vs female sex) was significantly associated with an accelerate rate for five of 12 transitions. Interpretation: We describe a multistate model in a healthy older population in whom the most common transition was from a healthy state to cancer. Our findings provide unique insights into the frequency of events, their transition rates, and the impact of age and sex. These results have implications for preventive health interventions and planning for appropriate levels of residential care in healthy ageing populations. Funding: The National Institutes of Health

    Domain Wall Spacetimes: Instability of Cosmological Event and Cauchy Horizons

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    The stability of cosmological event and Cauchy horizons of spacetimes associated with plane symmetric domain walls are studied. It is found that both horizons are not stable against perturbations of null fluids and massless scalar fields; they are turned into curvature singularities. These singularities are light-like and strong in the sense that both the tidal forces and distortions acting on test particles become unbounded when theses singularities are approached.Comment: Latex, 3 figures not included in the text but available upon reques

    The role of cytokine gene polymorphisms in the pathogenesis of abdominal aortic aneurysms: A case-control study

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    AbstractBackground: Cytokines are the primary mediators of inflammation and also influence matrix metalloproteinase expression, both of which are important in development of abdominal aortic aneurysm (AAA). A significant, but as yet unknown, familial factor contributes to the pathogenesis of AAA. Many cytokine genes contain polymorphic sites, some of which affect cytokine production in vitro. Cytokine gene polymorphisms may therefore influence the pathogenesis of AAA. The purpose of this study was to determine whether there is any association between cytokine gene polymorphisms and AAA. Methods and Results: This case-control study comprised 100 patients with AAA and 100 age-matched and sex-matched control subjects. For each case and control subject in the study, genotypes at the following cytokine gene polymorphic loci were determined: interleukin (IL)-1ÎČ +3953, IL-6 −174, IL-10 −1082, IL-10 −592, and tumor necrosis factors-α −308. Allele and genotype frequencies were compared between AAA and control groups, and odds ratios (OR) were calculated for the presence of AAA with each allele at each locus examined as risk factors. The IL-10 −1082 A allele was significantly more common in the AAA group than the control group (P =.03). The OR for the IL-10 −1082 A allele as a risk factor for AAA was 1.8 (95% confidence interval, 0.9-3.6). Discussion: These associations suggest a significant role for IL-10 in the pathogenesis of AAA. This association of AAA with the IL-10 −1082 A allele is also biologically plausible; the IL-10 −1082 A allele is associated with low IL-10 secretion, and it may be that AAA develops in patients who are unable to mount the same anti-inflammatory response as those who do not have AAA. (J Vasc Surg 2003;37:999-1005.
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