793 research outputs found

    ¿Por qué decidimos ser voluntarios?

    Get PDF
    VIII Jornades de Foment de la Investigació de la FCHS (Any 2002-2003)El voluntariado es un recurso humano que por su importancia como fenómeno social en auge, desde hace ya algunos años, merece su estudio desde la psicología social. Esta destacabilidad del voluntariado se refleja en las leyes, planes e incluso el código ético, creados para su definición dentro de unos parámetros y su equiparación, ya que existen muchos tipos de voluntariado y en muy diversos campos, poniendo límites, así, a la expresión de la conducta de ayuda, prosocial y altruista. Esta investigación es una parte de otra más extensa, y el objeto fundamental del fragmento que aquí se presenta pasa por hallar qué motivos llevan a iniciar el voluntariado en una organización. Concretamente, se ha estudiado el voluntariado en las organizaciones dedicadas a la acogida, rehabilitación y reinserción de drogodependientes, partiendo de una muestra de 52 sujetos, a la que se ha aplicado el “Cuestionario: Perfil del Voluntariado. 2001. Versión 1” Surgen así, como motivos más importantes las circunstancias personales, tales como tener un familiar tratado en la organización o ser uno mismo el que pasó como usuario de la organización y tras la rehabilitación y reinserción decidió hacerse voluntario. Son, por tanto, motivos internos, autocentrados, los más destacables. La importancia de este estudio subyace en su aprovechamiento para el reclutamiento y estrategias de sensibilización de los/las voluntarios/as de una organización. Y, por supuesto, en su profundización en un tema que no ha recibido la atención científica que merece

    Influencia de la altitud en la riqueza de especies de moluscos: variaciones en el valle de Alinyà, Alt Urgell, Lleida

    Get PDF
    The species richness of land molluscs is negatively correlated with altitude, while the altitudinal range of the species inhabiting at higher elevations is greater than in low levels. At the low scale of this study factors other than elevation may account better for the species richness.La riqueza de especies de moluscos terrestres está negativamente correlacionada con la altitud, mientras que el rango altitudinal de las especies lo está positivamente. En estudios locales como éste la altitud no explica suficientemente la distribución de la riqueza de especies

    Fauna malacológica de Les Planes de Son y La Mata de València (Alt Àneu, Pallars Sobirà, Pirineo Catalán): revisión biliográfica y nuevos datos

    Get PDF
    La revisió de citacions bibliogràfiques situades a les Planes de Son i la Mata de València (municipi d’Alt Àneu, Pallars Sobirà) ha permès identificar 33 espècies de mol·luscs (set de les quals corresponents a llimacs) presents històricament en la zona. Una campanya de camp portada a terme recentment (2006–2007) ha detectat 50 espècies de mol·luscs no-llimacs, dues de les quals representades amb dues subespècies cadascuna. Es proporcionen les dades detallades dels dos inventaris faunístics. Paraules clau: Pirineus, Fauna, Mollusca.The survey of bibliograpic information on the presence of molluscs at the Planes de Son and Mata de València (municipality of Alt Àneu, county of Pallars Sobirà, Catalan Pyrenees) has accounted for a list of 33 species of molluscs (seven of them are slugs) inhabiting historically this area. A current field survey (2006-2007) has detected 50 species of molluscs not slugs, two of these species are splitted in two subspecies. Detailed data from both faunistic inventories are provided. Key words: Pyrenees, Fauna, Mollusca.La revisión de las citas bibliográficas situadas en Les Planes de Son y La Mata de València (municipio de Alt Àneu, comarca del Pallars Sobirà, Pirineo Catalán) ha permitido identificar 33 especies de moluscos (siete de ellas correspondientes a babosas) presentes históricamente en la zona. Una reciente campaña de campo (2006-2007) ha detectado 50 especies de moluscos no babosas, dos de ellas representadas con dos subespecies cada una. Se proporcionan los datos detallados de los dos inventarios faunísticos. Palabras clave: Pirineo, Fauna, Mollusca

    Analysis of circulating microRNAs and their post-transcriptional modifications in cancer serum by on-line solid-phase extraction-capillary electrophoresis-mass spectrometry

    Get PDF
    In this paper, an on-line solid-phase extraction capillary electrophoresis-mass spectrometry (SPE-CE-MS) method is described for the purification, preconcentration, separation, and characterization of endogenous microRNA (miRNA) and their post-transcriptional modifications in serum. First, analysis by CE-MS was optimized using a standard mixture of hsa-miR-21-5p (miR-21-5p) and hsa-let-7g-5p (let-7g-5p). For SPE-CE-MS, a commercial silicon carbide (SiC) resin was used to prepare the microcartridges. Under the optimized conditions with standards, the microcartridge lifetime (>25 analyses) and repeatability (2.8% RSD for the migration times; 4.4 and 6.4% RSD for the miR-21-5p and let-7g-5p peak areas, respectively) were good, the method was linear between 25 and 100 nmol·L-1, and the limit of detection (LOD) was around 10 nmol·L-1 (50 times lower than by CE-MS). In order to analyze human serum samples, an off-line sample pretreatment based on phenol/chloroform/isoamyl alcohol (PCA) extraction was necessary prior to SPE-CE-MS. The potential of the SPE-CE-MS method to screen for B-cell chronic lymphocytic leukemia (CLL) was demonstrated by an analysis of serum samples from healthy controls and patients. MicroRNAs, specifically miR-21-5p and a 23 nucleotide long 5'-phosphorylated miRNA with 3'-uridylation (iso-miR-16-5p), were only detected in the CLL patients

    Jet mass and substructure of inclusive jets in √s = 7TeV pp collisions with the ATLAS experiment

    Full text link
    Journal of High Energy Physics 2012.5 (2012): 128 reproduced by permission of Scuola Internazionale Superiore di Studi Avanzati (SISSA)Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAMRecent studies have highlighted the potential of jet substructure techniques to identify the hadronic decays of boosted heavy particles. These studies all rely upon the assumption that the internal substructure of jets generated by QCD radiation is well understood. In this article, this assumption is tested on an inclusive sample of jets recorded with the ATLAS detector in 2010, which corresponds to 35 pb -1 of pp collisions delivered by the LHC at Rs = 7TeV. In a subsample of events with single pp collisions, measurements corrected for detector efficiency and resolution are presented with full systematic uncertainties. Jet invariant mass, kt splitting scales and N-subjettiness variables are presented for anti-kt R = 1.0 jets and Cambridge-Aachen R = 1.2 jets. Jet invariant-mass spectra for Cambridge-Aachen R = 1.2 jets after a splitting and filtering procedure are also presented. Leading-order parton-shower Monte Carlo predictions for these variables are found to be broadly in agreement with data. The dependence of mean jet mass on additional pp interactions is also explore

    Evaluation of ion mobility for the separation of glycoconjugate isomers due to different types of sialic acid linkage, at the intact glycoprotein, glycopeptide and glycan level.

    Get PDF
    The study of protein glycosylation can be regarded as an intricate but very important task, making glycomics one of the most challenging and interesting, albeit under-researched, type of "omics" science. Complexity escalates remarkably when considering that carbohydrates can form severely branched structures with many different constituents, which often leads to the formation of multiple isomers. In this regard, ion mobility (IM) spectrometry has recently demonstrated its power for the separation of isomeric compounds. In the present work, the potential of traveling wave IM (TWIMS) for the separation of isomeric glycoconjugates was evaluated, using mouse transferrin (mTf) as model glycoprotein. Particularly, we aim to assess the performance of this platform for the separation of isomeric glycoconjugates due to the type of sialic acid linkage, at the intact glycoprotein, glycopeptide and glycan level. Straightforward separation of isomers was achieved with the analysis of released glycans, as opposed to the glycopeptides which showed a more complex pattern. Finally, the developed methodology was applied to serum samples of mice, to investigate its robustness when analyzing real complex samples.Ion mobility mass spectrometry is a promising analytical technique for the separation of glycoconjugate isomers due to type of sialic acid linkage. The impact of such a small modification in the glycan structure is more evident in smaller analytes, reason why the analysis of free glycans was easier compared to the intact protein or the glycopeptides. The established methodology could be regarded as starting point in the separation of highly decorated glycoconjugates. This is an important topic nowadays, as differences in the abundance of some glycan isomers could be the key for the early diagnosis, control or differentiation of certain diseases, such as inflammation or cancer

    Testing Beam-Induced Quench Levels of LHC Superconducting Magnets

    Full text link
    In the years 2009-2013 the Large Hadron Collider (LHC) has been operated with the top beam energies of 3.5 TeV and 4 TeV per proton (from 2012) instead of the nominal 7 TeV. The currents in the superconducting magnets were reduced accordingly. To date only seventeen beam-induced quenches have occurred; eight of them during specially designed quench tests, the others during injection. There has not been a single beam- induced quench during normal collider operation with stored beam. The conditions, however, are expected to become much more challenging after the long LHC shutdown. The magnets will be operating at near nominal currents, and in the presence of high energy and high intensity beams with a stored energy of up to 362 MJ per beam. In this paper we summarize our efforts to understand the quench levels of LHC superconducting magnets. We describe beam-loss events and dedicated experiments with beam, as well as the simulation methods used to reproduce the observable signals. The simulated energy deposition in the coils is compared to the quench levels predicted by electro-thermal models, thus allowing to validate and improve the models which are used to set beam-dump thresholds on beam-loss monitors for Run 2.Comment: 19 page

    Supporting data for the MS identification of distinct transferrin glycopeptide glycoforms and citrullinated peptides associated with inflammation or autoimmunity

    Get PDF
    This data article presents the results of all the statistical analyses applied to the relative intensities of the detected 2D-DiGE protein spots for each of the 3 performed DiGE experiments. The data reveals specific subsets of protein spots with significant differences between WT and CD38-deficient mice with either Collagen-induced arthritis (CIA), or with chronic inflammation induced by CFA, or under steady-state conditions. This article also shows the MS data analyses that allowed the identification of the protein species which serve to discriminate the different experimental groups used in this study. Moreover, the article presents MS data on the citrullinated peptides linked to specific protein species that were generated in CIA(+) or CFA-treated mice. Lastly, this data article provides MS data on the efficiency of the analyses of the transferrin (Tf) glycopeptide glycosylation pattern in spleen and serum from CIA(+) mice and normal controls. The data supplied in this work is related to the research article entitled "identification of multiple transferrin species in spleen and serum from mice with collagen-induced arthritis which may reflect changes in transferrin glycosylation associated with disease activity: the role of CD38" [1]. All mass spectrometry data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with identifiers PRIDE: PXD002644, PRIDE: PXD002643, PRIDE: PXD003183 and PRIDE: PXD003163
    corecore