How to Add Apples and Pears: Non-Symmetric Nash Bargaining and the Generalized Joint Surplus

We generalize the equivalence of the non-symmetric Nash bargaining solution and the linear division of the joint surplus when bargainers use different utility scales. This equivalence in the general case requires the surplus each agent receives to be expressed in compatible, or comparable, units. This result is valid in the case of bargaining over multiple-issues. In addition, we discuss the requirements on the curvatures of the agents’ utility functions, or, in other words, on the bargainers’ attitudes towards risk.Bargaining Problems, Non-Symmetric Nash Bargaining Solution, Linear Sharing

Extensión de espacios duales de Frechet

Se extiende la definición de Grothendieck de DF-espacio al caso de cuerpos valuados no arquimedeanos y se prueban algunas de las principales propiedades. Se caracterizan los espacios topológicos ultrarregulares para los cuales el espacio de  funciones continuas con valores en un cuerpo resulta un DF-espacio provisto de la topología compacto abierta. Finalmente se dan condiciones necesarias y suficientes para que el espacio de funciones con valores vectoriales resulte con DF-espacio

The c.3274T> C mutation in the CFTR gene results in bronchiectasis and loss of lung function in a 44-year-old Peruvian woman: A very rare condition

CF is an autosomal recessive disease, requiring mutations to be present in both alleles in the CF transmembrane conductance regulatory gene (CFTR). The c.3274T> C (p.Tyr1092His) mutation is not registered in the “CFTR2 project” database, but it is registered in The Human Gene Mutation Database. Neither are the two DNAAF4 c.1177C> T (p.Leu393Phe) and DNAAF5 c.1195G> A (p.Glu399Lys) mutations found in the "CFTR Project”, and their clinical consequences are currently uncertain. Here, we report the case of a Peruvian woman presenting this mutation, bronchiectasis and loss of lung function and provide a review of the literature.La FQ es una enfermedad autosómica recesiva que requiere la presencia de mutaciones en ambos alelos del gen regulador de la conductancia transmembrana de la FQ (CFTR). La mutación c.3274T> C (p.Tyr1092His) no está registrada en la base de datos del “proyecto CFTR2”, pero está registrada en la base de datos de mutaciones de genes humanos. Ademas otras dos mutaciones DNAAF4 c.1177C> T (p.Leu393Phe) y DNAAF5 c.1195G> A (p.Glu399Lys) encontradas en el "Proyecto CFTR", son actualmente inciertas en sus consecuencias clínicas. A continuación, presentamos el caso de una mujer peruana que presenta esta mutación, bronquiectasias y pérdida de función pulmonar y se proporciona una revisión de la literatura

Tumor Microenvironment Heterogeneity: A Review of the Biology Masterpiece, Evaluation Systems, and Therapeutic Implications

A tumor can be considered as a highly heterogeneous functional tissue, connected and dependent on the microenvironment, which sends and receives signals to and from the tumor tissue itself. Tumor cells alter the mechanical properties of the microenvironment in order to create favorable conditions for their proliferation. Stromal cells and non‐cellular elements of the extracellular matrix (ECM), including the host immune system, the fibrous scaffolding, the fundamental substance, and blood vascularization can determine tumoral cell morphologies, functions, aggressiveness, and response to treatment, as well as an accurate assessment of prognosis of the patients. Robust morphometric digital pathology techniques that are able to standardize measurements and analyse whole sets of immunohistochemical images are called for to identify, describe, and quantify the elements of the ECM. The computer‐automated segmentation algorithms are therefore required to increase the knowledge on the tumor microenvironment heterogeneity and to provide new therapeutic targets

First Results from the rapid-response spectrophotometric characterization of Near-Earth Objects

As part of our multi-observatory, multi-filter campaign, we present \rmi color observations of 82 Near-Earth Objects (NEOs) obtained with the RATIR instrument on the 1.5m robotic telescope at the San Pedro Martir's National Observatory in Mexico. Our project is particularly focused on rapid response observations of small ($\lesssim 850$ m) NEOs. The rapid response and the use of spectrophotometry allows us to constrain the taxonomic classification of NEOs with high efficiency. Here we present the methodology of our observations and our result, suggesting that the ratio of C-type to S-type asteroids in a size range of $\sim$30-850m is 1.1, which is in accordance with our previous results. We also find that 10$\%$ of all NEOs in our sample are neither C- nor S-type asteroidsComment: 31 pages, 4 tables, 10 figure

Impact of the ocean-atmosphere coupling on high-resolution future projections for the Mediterranean sea and surrounding climate from the Med-CORDEX ensemble

Med-CORDEX is an international initiative that aims at developing fully coupled high resolution Regional Climate System Models (RCSMs) for the Mediterranean basin. After 11 years of work an ensemble of more than 25 multi-model and multi–scenario climatic simulations is now available (Darmaraki et al., 2019; Soto-Navarro et al., 2020). In this study, we analyze the impact of the high-resolution representation of the Mediterranean Sea and of the interaction between ocean and atmosphere, explicitly resolved in the Med-CORDEX simulations, in the projected evolution of the most relevant climatic variables for the Mediterranean basin and the adjacent regions during the 21st century. The final goal is to quantify up to what extent including the explicit and high-resolution representation of the ocean-atmosphere coupling is relevant for regional climate projections. The preliminary results show that, in general, higher resolution coupled simulations project a lower increase in the Sea Surface Temperature (SST) than lower resolution runs. This translates in a smaller input of heat and humidity to the atmosphere that, in turn, affect the cloud cover and precipitation over the basin and the adjacent continental areas. These changes are the result of a better representation of the Mediterranean Sea functioning in the Med-CORDEX RCSMs. In particular, they resolve better the mesoscale processes of the basin, which are partly responsible of the heat transport from the surface to deeper layers, and the ocean-atmosphere feedback that regulates the heat exchange

The MED-CORDEX ensemble future climate projections for the Mediterranean Sea: impacts of the high resolution and ocean-atmosphere coupling

Med-CORDEX is an international initiative that aims at developing fully coupled high resolution Regional Climate System Models (RCSMs) for the Mediterranean basin. After 11 years of work an ensemble of more than 25 multi-model and multi–scenario climatic simulations is now available. In this study, we analyze the impact of the high-resolution representation of the Mediterranean Sea and of the interaction between ocean and atmosphere, explicitly resolved in the Med-CORDEX simulations, in the projected evolution of the most relevant climatic variables for the Mediterranean basin and the adjacent regions during the 21st century. The final goal is to quantify up to what extent including the explicit and high-resolution representation of the ocean-atmosphere coupling is relevant for regional climate projections. The preliminary results show that, in general, higher resolution coupled simulations project a lower increase in the Sea Surface Temperature (SST) than lower resolution runs. This translates in a smaller input of heat and humidity to the atmosphere that, in turn, affect the cloud cover and precipitation over the basin and the adjacent continental areas. These changes are the result of a better representation of the Mediterranean Sea functioning in the Med-CORDEX RCSMs. In particular, they resolve better the mesoscale processes of the basin, which are partly responsible of the heat transport from the surface to deeper layers, and the ocean-atmosphere feedback that regulates the heat exchange.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Dentro de un aula hospitalaria

“Dentro de un aula hospitalaria” es el tema principal que se aborda en este Trabajo de Fin de Grado. El presente trabajo se centra en el proceso de enseñanza-aprendizaje que se realiza con los niños en un contexto hospitalario y consta de dos partes bien diferenciadas. En la primera se desarrolla una fundamentación teórica donde se define el concepto de aula hospitalaria y se hace un recorrido histórico desde su origen hasta la actualidad. En la segunda parte está formada por un conjunto de actividades educativas para llevar a cabo en el aula hospitalaria.Grado en Educación Primari

Redes de aprendizaje profesional docente en contextos escolares chilenos

Aunque las redes docentes de aprendizaje profesional son una estrategia de amplia difusión, hay todavía poca evidencia sobre los significados y condiciones organizacionales que las viabilizan. Este trabajo examinó las valoraciones docentes y, a la vez, los factores contextuales y organizativos que favorecen el desarrollo profesional en la Red de Aprendizaje Docente (RAD) impulsada por un municipio de la región de Ñuble, en el sur de Chile, durante 2018 y 2019. La experiencia fue analizada considerando los aportes de la literatura sobre las comunidades de aprendizaje profesional, las comunidades de aprendizaje en red y las redes de mejora impulsadas por el gobierno chileno. Basado en el análisis temático de los discursos docentes en dos grupos focales, los resultados muestran una positiva percepción sobre la participación en una red colaborativa con docentes de distintos niveles y asignatura, e indican que el trabajo entre pares fue una oportunidad de aprendizaje en temas curriculares, de reflexión compartida sobre sus desempeños, lo que ha significado cierto bienestar personal. En lo que refiere a los aspectos organizacionales para que una red docente opere adecuadamente, los docentes destacan que quienes lideren la red deben evidenciar solvencia y legitimidad pedagógica; debe existir compromiso docente, una planificación que oriente el trabajo y que tenga en cuenta horarios libres para participar. Un hallazgo atípico fue que valoraran el carácter obligatorio de la participación en la red, lo que contrasta con la literatura que enfatiza el carácter autogestionado de estas comunidades