35,195 research outputs found

    Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand.

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    OBJECTIVE: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV. DESIGN: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand. METHODS: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters. RESULTS: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean. CONCLUSION: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age

    Some frequency domain considerations upon human respiratory mechanics

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    The aim of this paper is to present a brief analysis of recent results considering human respiratory mechanics. The final purpose of the investigation is to provide a fast method for identification of airway mechanics, in order to assist the medical staff in obtaining a diagnosis of the patient within the context of performing routine evaluation of the respiratory function. Considerations are made with respect to the future potential of the method as a screening technique on a large number of populations

    Iglesia de LeĂłn, y monasterios antiguos y modernos de la misma ciudad

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    Copia digital. Valladolid : Junta de Castilla y LeĂłn. ConsejerĂ­a de Cultura y Turismo, 2009-2010La menciĂłn de tomo consta al fin de la obra.Sign. : [ ]\p2\s, A-Z\p4\s, 2A-2B\p4\s.Port. con grab. xil.Las h. de grab. calc.:"Pets. Pauls. Fernz. delint. Leg. Joan Minguet sculpt. Mat. A. 1784", epitafios. "Joan. Alvarez delin. Leg. an. 1782". "Jos. Assensio incidit 1786", piedra de la Capilla de Sto. Martino. Las h. de grab. pleg. cal.: "Asensio el Padre", uno de los pilares del Cuerpo de la iglesia de San Isidro de LeĂłn. "Fern. Sanchez lo delineo. Josef Assensio lo grabĂł en Madd", fachada principal de la Santa Iglesia de LeĂłn. "Manuel Navarro ft.", "Josef assensio lo grabo", fachadas de la Iglesia de LeĂłnrepresentando alzados de la Catedral de LeĂłn

    Sfp1 and Rtg3 reciprocally modulate carbon source-conditional stress adaptation in the pathogenic yeast Candida albicans

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    Acknowledgements We thank Aaron Mitchell, Dominique Sanglard and Suzanne Noble for their generosity in providing mutant collections, and Linghuo Jiang for generously providing strains. We also thank Susan Budge for her support and excellent technical assistance. We also thank the qPCR Facility in the Institute of Medical Sciences, and particularly Fiona Saunders for her great advice and help. SLK was supported by a PhD scholarship from the University of Aberdeen. AJPB was supported by the UK Biotechnology and Biological Research Council (BB/F00513X/1; BB/K017365/1), by the European Research Council (STRIFE Advanced Grant; ERC-2009-AdG-249793), and by the UK Medical Research Council (MR/M026663/1). AJPB and CAM were also supported by the Wellcome Trust (088858; 097377), and by the MRC Centre for Medical Mycology and the University of Aberdeen (MR/N006364/1).Peer reviewedPublisher PD

    Fixed-term Contracts, Transitions and Wage Growth: Evidence from Spain

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    Employment instability is considered one of the main problems of the Spanish labour market. Thus, the proportion of temporary workers in Spain is around 30 per cent that is the highest rate of the European Union countries. The persistence of this situation could increase the risk of labour market segmentation. This paper presents new evidence of the factors affecting workers' transition from temporary work to permanent one and analyses whether this transition has a positive effect on wage growth. The former objective is obtained by estimating discrete choice models and the latter by estimating a wage growth equation correcting for selectivity bias through the two-step method developed by Trost and Lee (1984). The data are obtained from the second and third waves of the Spanish Household Panel Survey (INE 1996) conducted over the period 1995–1996. The main results are, on the one hand, that personal and job characteristics have a significant influence on the probability of becoming a permanent worker and, on the other hand, that this transition has an important positive effect on wage growth.labour force transitions, temporary and permanent workers, wage growth

    Search for photospheric footpoints of quiet Sun transition region loops

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    CONTEXT:The footpoints of quiet Sun Transition Region (TR) loops do not seem to coincide with the photospheric magnetic structures appearing in traditional low-sensitivity magnetograms. AIMS: To look for the so-far unidentified photospheric footpoints of TR loops using G-band bright points (BPs) as proxies for photospheric magnetic field concentrations. METHODS: Comparison of TR measurements with SoHO/SUMER and photospheric magnetic field observations obtained with the Dutch Open Telescope. RESULTS: Photospheric BPs are associated with bright TR structures, but they seem to avoid the brightest parts of the structure. BPs appear in regions that are globally redshifted, but they avoid extreme velocities. TR explosive events are not clearly associated with BPs. CONCLUSIONS: The observations are not inconsistent with the BPs being footpoints of TR loops, although we have not succeeded to uniquely identify particular BPs with specific TR loops.Comment: Accepted for publication in A&A. 10 pages, 10 figures. Due to size limitations, the quality of fig3 is not goo

    Magnetic properties of photospheric regions having very low magnetic flux

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    The magnetic properties of the quiet Sun are investigated using a novel inversion code, FATIMA, based on the Principal Component Analysis of the observed Stokes profiles. The stability and relatively low noise sensitivity of this inversion procedure allows for the systematic inversion of large data sets with very weak polarization signal. Its application to quiet Sun observations of network and internetwork regions reveals that a significant fraction of the quiet Sun contains kilogauss fields (usually with very small filling factors) and confirms that the pixels with weak polarization account for most of the magnetic flux. Mixed polarities in the resolution element are also found to occur more likely as the polarization weakens.Comment: To apapear in ApJ. 39 pages, 12 figures (2 of them are color figures

    NACCS 27th Annual Conference

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    SabidurĂ­a, Lucha, y LiberaciĂłn: Youth, Community & Culture en el Nuevo SolMarch 22-25, 2000Downtown Hiltonhttps://scholarworks.sjsu.edu/naccs_programs/1017/thumbnail.jp
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