Sensitive Indicators to Rehabilitation Nursing Care in a Rehabilitation Program for People in the Surgical Process, Based on the Health Quality Model.

Abstract Continued improvement in care is one of the primary objectives of Rehabilitation Nursing. With the current medical-surgical evolution, the Rehabilitation Nurse faces new challenges related to the recovery, enhancement and maintenance of the functionality and capacity of the person in the surgical process. The identification of the indicators that are sensitive to the care of Rehabilitation Nursing, presents in the intervention plans carried out, allow us to measure the quality of the care provided and guarantee the excellence of the care performed. Objective: To identify sensible indicators for Rehabilitation Nursing care, presents in the Rehabilitation programs executed to the person in the surgical process, based on the health quality model. Methods: A systematic review of the literature was carried out through the EBSCO host (MEDLINE with Full Text, CINAHL Plus with Full Text and MedicLatina), using the PI [C] O method. Results: 49 indicators were identified, with emphasis on: “Percentage of clients to whom rehabilitation plan and/or rehabilitation program has been implemented to maximize functional capabilities”; “Percentage of clients with potential to improve the walking ability” and “Percentage of clients with risk of muscle stiffness who were monitored for the range of joint motion through the goniometer”. Conclusion: The surgical patient, in the various areas of intervention (vascular, neurosurgical, orthopedic), presents health gains with the implementation of Rehabilitation programs, with 49 indicators that are sensitive to Rehabilitation Nursing care in the programs executed

Mathematical Modeling Of Convective Drying With Infrared Radiation Of Moringa Oleifera Grains

Mathematical models applied to drying assists in sizing dryers, predicting drying rate, improvement of drying conditions and assessment of process quality. Thus, the aim of this study was to evaluate the fitting of Page, Midilli, Newton and second law of Fick models to the experimental data of convective drying with application of infrared radiation of Moringa oleifera L. grains. The effects of factors - air temperature (30-60 degrees C), air velocity (0.55 to 1.05 m s(-1)), infrared radiation application time (120-300 s) and infrared radiation intensity (1500-4500 W) on the effective diffusivity, moisture content, water activity and drying time was also evaluated. The models explained more than 98% of the drying behavior and the Midilli model showed the best fit for the experimental data. The effective diffusivity was calculated using the equation proposed by the solution of second law of Fick, for spherical shape, and the values ranged from 6.44x10(-10) to 9.89x10(-10) m(2) s(-1). The factors air temperature and infrared radiation application time were significant for all studied variables, considering 90% of confidence.19768669

Analysis of male reproductive parameters in a murine model of mucopolysaccharidosis type I (MPS I)

Mucopolysaccharidosis (MPS) I is a lysosomal storage disorder (LSD) that is characterised by alpha-L-idu-ronidase (Idua) deficiency and continuous deposition of glycosaminoglycans (GAGs), which consequently interferes with cell signalling mechanisms and results in multisystemic and progressive symptoms. The animal model of MPS I (Idua-/-) has been widely studied to elucidate the consequences and progression of the disorder; however, studies specifically assessing the male reproductive tract are lacking. The aim of this study was to evaluate some of the reproductive characteristics of male MPS I mice in two phases of life. Reproductive organ biometry, sperm counts, sperm morphological evaluation, plasma testosterone measurements and histopathological, histomorphometrical and immunohistochemical analysis were performed in 3- and 6-month-old C57BL/6 Idua+/+ and Idua-/- mice. Seminal vesicle weights were decreased in both the 3- and 6-month-old Idua-/- mice. Decrease in sperm counts and the majority of the histopathological signs were observed in the 6-month-old Idua-/- mice. No differences were detected in the sperm morphological analysis. Immunohistochemistry revealed that seminiferous tubules from 3-month-old Idua-/- mice were more intensely stained with anti-caspase-3 than 3-month-old Idua+/+ mice, but no difference was found at 6 months. These results suggest that MPS I interferes with male reproductive parameters both in 3 and 6-month-old animals and histopathological signs are more pronounced in 6-month-old mice, indicating that the effects of the disorder may intensify with the disease progression.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)AFIPFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Biosci, Santos, SP, BrazilUniv Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Biosci, Santos, SP, BrazilWeb of Scienc

Effect of chitosan and calcium salts in the maintenenance of shelf-life and quality of fresh-cut pineapple

Postprint (published version

Letramento de Meninas em Programação através do Pensamento Computacional para Compreensão de Problemas/ Girls Literacy in Programming through Computational Thinking to Understand Problems

Este trabalho trata da retração das mulheres na carreira da ciência da computação e das dificuldades de compreensão e de suas implicações no processo de formação de programadores. Desta forma o trabalho propõe a oferta de oficinas baseadas nos pilares do pensamento computacional para meninas do quinto ao nono ano do ensino fundamental em escola pública. A proposta é resultante de uma experiência de iniciação à programação com uma estudante surda, e tem como objetivo desenvolver o letramento em programação através do pensamento computacional para compreensão dos problemas, despertando o interesse de meninas pela áre

Autophagy-targeted therapy to modulate age-related diseases: success, pitfalls, and new directions

Autophagy is a critical metabolic process that supports homeostasis at a basal level and is dynamically regulated in response to various physiological and pathological processes. Autophagy has some etiologic implications that support certain pathological processes due to alterations in the lysosomal-degradative pathway. Some of the conditions related to autophagy play key roles in highly relevant human diseases, e.g., cardiovascular diseases (15.5%), malignant and other neoplasms (9.4%), and neurodegenerative conditions (3.7%). Despite advances in the discovery of new strategies to treat these age-related diseases, autophagy has emerged as a therapeutic option after preclinical and clinical studies. Here, we discuss the pitfalls and success in regulating autophagy initiation and its lysosome-dependent pathway to restore its homeostatic role and mediate therapeutic effects for cancer, neurodegenerative, and cardiac diseases. The main challenge for the development of autophagy regulators for clinical application is the lack of specificity of the repurposed drugs, due to the low pharmacological uniqueness of their target, including those that target the PI3K/AKT/mTOR and AMPK pathway. Then, future efforts must be conducted to deal with this scenery, including the disclosure of key components in the autophagy machinery that may intervene in its therapeutic regulation. Among all efforts, those focusing on the development of novel allosteric inhibitors against autophagy inducers, as well as those targeting autolysosomal function, and their integration into therapeutic regimens should remain a priority for the field.Fil: Martins, Waleska Kerllen. Anhanguera University; BrasilFil: Silva, Maryana do Nascimento da. Anhanguera University; BrasilFil: Pandey, Kiran. University of New York; Estados UnidosFil: Maejima, Ikuko. Gunma University; JapónFil: Ramalho, Ercília. Anhanguera University; BrasilFil: Olivon, Vania Claudia. Anhanguera University; BrasilFil: Diniz, Susana Nogueira. Anhanguera University; BrasilFil: Grasso, Daniel Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni; Argentin

Behavioural and cognitive effects of simvastatin dose used in stimulation of bone regeneration in rats

PURPOSE: To analyze the effects of simvastatin (SVT) in the locomotion, anxiety and memory of rats, as a reflection of the administration of a minimum dose capable of stimulating bone regeneration in defects in the calvariae.METHODS: Surgical procedures were performed in 15 female Wistar rats, 2-month old, to insert the grafting material regenerator (Bone-ceramic(r)) and/or SVT, followed by behavioural and cognitive assessments in the 7th, 30th and 60th days post surgery.RESULTS: The SVT locally applied with the goal of bone regeneration in defects created in rat calvariae does not interfere with locomotion, anxiety levels and/or memories of rats, except for the first week following surgery, when an anxiolytic effect was observed, as a result of a possible central action.CONCLUSION: Failure to provoke any response within 30 and 60 days post surgical procedures suggests that SVT may constitute a good choice in stimulating bone regeneration without affecting the long term neural functions

A RELAÇÃO ENTRE A PERCEPÇÃO DE PRÁTICAS DE RESPONSABILIDADE SOCIAL CORPORATIVA E A INTENÇÃO DE ROTATIVIDADE DOS PROFISSIONAIS

Analisou-se neste artigo a relação entre a percepção de práticas de responsabilidade social corporativa (RSCORP) e a intenção de rotatividade (IR) de profissionais brasileiros de diferentes Estados e setores econômicos. Coletou-se dados por meio de questionário baseado nas escalas de percepção de práticas de responsabilidade social corporativa (TURKEY, 2009b) e escala de intenção de rotatividade (SIQUEIRA et al., 2012) junto a 100 profissionais. Os dados foram analisados por meio de modelagem em equações estruturais utilizando o software Smart PLS 3. A síntese dos resultados indica que a percepção de práticas de responsabilidade social corporativa influencia negativamente a intenção de rotatividade dos profissionais. Em outros termos, quanto mais positiva for a percepção de práticas de responsabilidade social corporativa menor será a intenção de rotatividade. Os resultados sugerem uma interdependência entre as dimensões individual e organizacional que determinam o pensamento, o planejamento e vontade de deixar uma organização. Esta interdependência faz com que o profissional ao perceber que a sua organização adota práticas de responsabilidade social tenha um sentimento de comprometimento e confiança com a organização, diminuindo com isso, a intenção de rotatividade. Os dados revelaram ainda que ações de responsabilidade social voltadas para os grupos de stakeholders sociais e não sociais e empregados afetam positivamente a percepção de práticas de responsabilidade social corporativa. Os resultados levam à rejeição das hipóteses de que as ações destinadas a consumidores e governo afetam positivamente esta percepção

The impact of urban air pollution exposure on the development of alterations on oxidative stress and behavioral parameters in adult mice

FAPESP, CEPID and AFIP

Hábitos alimentares de crianças: análise da influência parental

Objetivo: Avaliar a influência dos pais na formação dos hábitos alimentares de crianças em idade pré-escolar e escolar. Materiais e Métodos: Trata-se de pesquisa observacional transversal, com abordagem quantitativa de caráter exploratório. A população de estudo foi constituída por crianças com idade entre 2 e 10 anos. Foram aplicados dois questionários, o Comprehensive Feeding Practices Questionnaire (CFPQ) e o Parent Mealtime Action Scale (PMAS). Resultados: Participaram 53 crianças, com prevalência de mães respondendo os questionários (91,8%). Sobre o estado nutricional avaliado pelo IMC, tanto os pais (59,2%), quanto as crianças (53%) se encontram em eutrofia. Quanto aos resultados do CFPQ, o maior valor médio observado foi no domínio “orientação de alimentação saudável” (4,17). E a menor média observada foi no domínio “regulação de emoções/alimentos como recompensa” (1,58). Quanto ao PMAS, o maior valor médio observado foi no domínio “limite para guloseimas” (2,77). E a menor média observada foi no domínio “modelo de consumo de guloseimas” (1,60). Não foram encontradas diferenças nos valores médios obtidos nos dois questionários considerando o estado nutricional da criança (p>0,05). Conclusão: Tendo em vista os resultados como um todo, observam-se pontos positivos e negativos. Pois os pais demonstram preocupação com a alimentação dos filhos e impõem limites para o consumo de alimentos não saudáveis.  Por outro lado, grande parte dos pais colocam pressão sobre as crianças para que consumam determinados alimentos. De modo geral, o conjunto de ações reflete de modo positivo no estado nutricional tanto dos pais, quanto dos filhos