Descriptive and spatial epidemiology of bovine cysticercosis in North-Eastern Spain (Catalonia).

From March 2005 to December 2007, 284 animals from 67 cattle farms (24 dairy and 43 beef) affected by bovine cysticercosis were detected in the region of Catalonia (North-Eastern Spain). Dairy farms were almost twice more likely to be affected than beef farms (OR=1.79, 95% CI=1.08-2.96, p<0.05), and infected premises have a statistically significant (p<0.05) larger number of animals when compared to uninfected farms in Catalonia. The geographical distribution of the infected farms was evaluated and two statistically significant clusters were identified. The most likely cluster was located in the western part of the study region, with 8 out of 10 farms infected. Epidemiological investigations revealed that the 8 farms belonged to the same company. The secondary cluster was located in Eastern Catalonia with 12 infected farms out of 167 cattle farms. No epidemiological links were found among the 12 infected premises. A questionnaire, based on the EFSA risk assessment, was used to assess the most likely route of introduction into each affected farm. Water supply for animals was the route with the highest score in 41.8% of the cases

From 1D convolutional codes to 2D convolutional codes of rate 1/n

In this paper we introduce a new type of superregular matrices that give rise to novel constructions of two-dimensional (2D) convolutional codes with finite support. These codes are of rate 1=n and degree d with n d +1 and achieve the maximum possible distance among all 2D convolutional codes with finite support with the same parameters

Maximum distance separable 2D convolutional codes

Maximum distance separable (MDS) block codes and MDS 1D convolutional codes are the most robust codes for error correction within the class of block codes of a fixed rate and 1D convolutional codes of a certain rate and degree, respectively. In this paper, we generalize this concept to the class of 2D convolutional codes. For that, we introduce a natural bound on the distance of a 2D convolutional code of rate $k/n$ and degree $delta$ , which generalizes the Singleton bound for block codes and the generalized Singleton bound for 1D convolutional codes. Then, we prove the existence of 2D convolutional codes of rate $k/n$ and degree $delta$ that reach such bound when $n geq k (({(lfloor ({delta }/{k}) rfloor + 2)(lfloor ({delta }/{k}) rfloor + 3)})/{2})$ if $k {nmid } delta$ , or $n geq k (({(({delta }/{k}) + 1)(({delta }/{k}) + 2)})/{2})$ if $k mid delta$ , by presenting a concrete constructive procedure

The eVALuate study: two parallel randomised trials, one comparing laparoscopic with abdominal hysterectomy, the other comparing laparoscopic with vaginal hysterectomy

OBJECTIVE: To compare the effects of laparoscopic hysterectomy and abdominal hysterectomy in the abdominal trial, and laparoscopic hysterectomy and vaginal hysterectomy in the vaginal trial. DESIGN: Two parallel, multicentre, randomised trials. Setting 28 UK centres and two South African centres. Participants 1380 women were recruited; 1346 had surgery; 937 were followed up at one year. PRIMARY OUTCOME: outcome Rate of major complications. RESULTS: In the abdominal trial laparoscopic hysterectomy was associated with a higher rate of major complications than abdominal hysterectomy (11.1% v 6.2%, P = 0.02; difference 4.9%, 95% confidence interval 0.9% to 9.1%) and the number needed to treat to harm was 20. Laparoscopic hysterectomy also took longer to perform (84 minutes v 50 minutes) but was less painful (visual analogue scale 3.51 v 3.88, P = 0.01) and resulted in a shorter stay in hospital after the operation (3 days v 4 days). Six weeks after the operation, laparoscopic hysterectomy was associated with less pain and better quality of life than abdominal hysterectomy (SF-12, body image scale, and sexual activity questionnaires). In the vaginal trial we found no evidence of a difference in major complication rates between laparoscopic hysterectomy and vaginal hysterectomy (9.8% v 9.5%, P = 0.92; difference 0.3%, − 5.2% to 5.8%), and the number needed to treat to harm was 333.We found no evidence of other differences between laparoscopic hysterectomy and vaginal hysterectomy except that laparoscopic hysterectomy took longer to perform (72 minutes v 39 minutes) and was associated with a higher rate of detecting unexpected pathology (16.4% v 4.8%, P = < 0.01). However, this trial was underpowered. CONCLUSIONS: Laparoscopic hysterectomy was associated with a significantly higher rate of major complications than abdominal hysterectomy. It also took longer to perform but was associated with less pain, quicker recovery, and better short term quality of life. The trial comparing vaginal hysterectomy with laparoscopic hysterectomy was underpowered and is inconclusive on the rate of major complications; however, vaginal hysterectomy took less time

Monitoring nanoparticle dissolution via fluorescence-colour shift

[La(OH)]2+[ICG]−2 and [La(OH)]2+2[PTC]4− inorganic–organic hybrid nanoparticles (IOH-NPs) with indocyanine green (ICG) and perylene-3,4,9,10-tetracarboxylate (PTC) as fluorescent dye anions are used for emission-based monitoring of the dissolution of nanoparticles. Whereas ICG shows a deep red emission in the solid [La(OH)]2+[ICG]−2 IOH-NPs, the emission of PTC in the solid [La(OH)]2+2[PTC]4− IOH-NPs is completely quenched due to π-stacking. After nanoparticle dissolution, the emission of freely dissolved ICG is weak, whereas freely dissolved PTC shows intense green emission. We report on the synthesis of IOH-NPs and nanoparticle characterization as well as on the fluorescence properties and how to avoid undesirable energy transfer between different fluorescent dyes. The emission shift from red (intact solid nanoparticles) to green (freely dissolved dye anions), indicating nanoparticle dissolution, is shown for aqueous systems and verified in vitro. Based on this first proof-of-the-concept, the IOH-NP marker system can be interesting to monitor nanoparticle dissolution in cells and tissues of small animals and to evaluate cell processes and/or drug-delivery strategies

pH-Dependent fluorescence of [La(OH)(2)](+)[ARS](-) hybrid nanoparticles for intracellular pH-sensing

Saline inorganic–organic hybrid nanoparticles (IOH-NPs) [La(OH)2]+[ARS]− (ARS: alizarin red S) are prepared in water as a new compound (particle size: 47 ± 7 nm, ARS load: 65 wt%). The IOH-NPs not only show a pH-dependent absorption colour but also a pH-dependent fluorescence with green emission at pH 5.0–9.0 and red emission at pH < 4.5. According to first in vitro studies, the pH-dependend fluorescence can be used to monitor nanoparticle internalization in cells as well as the respective intracellular pH

Under-ice observations of water column temperature, salinity and spring phytoplankton dynamics: Eastern Bering Sea shelf

The inundation of two moored platforms by sea ice in late winter and early spring of 1995 provided unique time series of water column temperature, salinity, estimated chlorophyll-a, and phytoplankton fluorescence under advancing and retreating sea ice. One platform was located at 72 m in the weakly advective middle shelf regime. Here, chlorophyll-a concentrations began increasing shortly after the arrival of the ice (arch) during the period of weak stratification and continued to increase while wind actively mixed the water column to \u3e60 m. Changes in water column structure and properties resulted from an event of strong advection rather than vertical fluxes. During winter, such advective events can replenish the nutrients required to support the rich blooms that occur over the middle shelf during spring. The advancing ice was associated with the coldest waters and a deep (\u3e50 m ) mixed layer. The ice melt enhanced the two-layer system previously established by advection. A second mooring was located at the 120 misobath on the more advective outer shelf. The ice reached this site on April 6, and chlorophyll-a concentrations increased as the sea ice melted. At the third mooring, located on the shelf farther south beyond the range of ice, the spring bloom began on ~ May 9

Ruminant pestiviruses in North Africa

Ruminant pestiviruses are widely distributed worldwide, causing congenital disease and massive economic losses. Although ruminant production is an important economic sector in North Africa, the knowledge about pestiviruses is scarce. The present study aimed at assessing the presence of Pestivirus in cattle in Algeria, and to review the data available on ruminant pestiviruses in North Africa. A cross-sectional study was conducted on dairy farms from North-Western Algeria. Blood samples from 234 dairy cattle from 31 herds were collected. All sera were analysed for the presence of antibodies using a commercial iELISA. The presence of Pestivirus RNA was also assessed by using a Reverse Transcription-PCR, and PCR-positive samples were sequenced. Risk factors related to Pestivirus infection were also analysed. The review of the presence of ruminant pestiviruses in North Africa was performed using a systematic search and compilation methodology of the peer-reviewed literature available in order to identify gaps of knowledge for future research. The seroprevalence at population and farm levels obtained in the present study (59.9% and 93.5%, respectively) concur with data reported in neighbouring countries. Risk factors associated with Pestivirus infection in cattle were the presence of sheep in the herd and the animal category (cow vs heifer). Furthermore, we confirmed the presence of BVDV-1a in Algeria. The scarce data suggest an endemic epidemiological scenario of pestivirus in livestock. The lack of studies about the epidemiology and molecular variability of ruminant pestiviruses in livestock and wildlife in North Africa is of concern for animal health and wildlife conservation, and needs to be addressed.info:eu-repo/semantics/acceptedVersio