7 research outputs found
Building the genomic nation: ‘Homo Brasilis’ and the ‘Genoma Mexicano’ in comparative cultural perspective
- Author
- Appelbaum NP
- Barahona A
- Carlos López-Beltrán
- Cavalli-Sforza LL
- Cunin E
- Ernesto Schwartz-Marín
- Freyre G
- Fry PH
- Fry PH
- Gall O
- García Murcia MAA
- García-Deister V
- García-Deister V
- Gaspar Neto VV
- Gledhill J
- Gleizer D
- Globo
- Guerrero Mothelet V
- Gómez Izquierdo JJ
- Gómez Izquierdo JJ
- Hartigan J
- Heath D
- Hofbauer A
- Hunt LM
- Kaufmann RFM
- Koenig BA
- Lewontin RC
- Lima NT
- López-Beltrán C
- López-Beltrán C
- Magnoli D
- Maio MC
- Michael Kent
- Navarrete Linares F
- Nelson A
- Pena SDJ
- Pena SDJ
- Pena SDJ
- Pena SDJ
- Peter Wade
- Pálsson G
- Rabinow P
- Reardon J
- Ricardo Ventura Santos
- Rose N
- Rutsch M
- Saade Granados M
- Salzano FM
- Schwartz-Marín E
- Stepan NL
- Suárez-Díaz E
- Telles EE
- Tenorio M
- Vasconcelos J
- Vergara Silva F
- Vivette García-Deister
- Wailoo K
- Publication venue
- SAGE Publications
- Publication date
- 20/11/2015
- Field of study
This article explores the relationship between genetic research, nationalism and the construction of collective social identities in Latin America. It makes a comparative analysis of two research projects – the ‘Genoma Mexicano’ and the ‘Homo Brasilis’ – both of which sought to establish national and genetic profiles. Both have reproduced and strengthened the idea of their respective nations of focus, incorporating biological elements into debates on social identities. Also, both have placed the unifying figure of the mestizo/mestiço at the heart of national identity constructions, and in so doing have displaced alternative identity categories, such as those based on race. However, having been developed in different national contexts, these projects have had distinct scientific and social trajectories: in Mexico, the genomic mestizo is mobilized mainly in relation to health, while in Brazil the key arena is that of race. We show the importance of the nation as a frame for mobilizing genetic data in public policy debates, and demonstrate how race comes in and out of focus in different Latin American national contexts of genomic research, while never completely disappearing
Building the genomic nation: ‘Homo Brasilis’ and the ‘Genoma Mexicano’ in comparative cultural perspective
- Author
- Appelbaum NP
- Barahona A
- Carlos López-Beltrán
- Cavalli-Sforza LL
- Cunin E
- Ernesto Schwartz-Marín
- Freyre G
- Fry PH
- Fry PH
- Gall O
- García Murcia MAA
- García-Deister V
- García-Deister V
- Gaspar Neto VV
- Gledhill J
- Gleizer D
- Globo
- Guerrero Mothelet V
- Gómez Izquierdo JJ
- Gómez Izquierdo JJ
- Hartigan J
- Heath D
- Hofbauer A
- Hunt LM
- Kaufmann RFM
- Koenig BA
- Lewontin RC
- Lima NT
- López-Beltrán C
- López-Beltrán C
- Magnoli D
- Maio MC
- Michael Kent
- Navarrete Linares F
- Nelson A
- Pena SDJ
- Pena SDJ
- Pena SDJ
- Pena SDJ
- Peter Wade
- Pálsson G
- Rabinow P
- Reardon J
- Ricardo Ventura Santos
- Rose N
- Rutsch M
- Saade Granados M
- Salzano FM
- Schwartz-Marín E
- Stepan NL
- Suárez-Díaz E
- Telles EE
- Tenorio M
- Vasconcelos J
- Vergara Silva F
- Vivette García-Deister
- Wailoo K
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
The effects of new formulations based on Gum Arabic on antioxidant capacity of tomato (Solanum lycopersicum L.) fruit during storage
- Author
- A Agourram
- A Ali
- A Ali
- A Chrysargyris
- A Naeem
- AA Lo'ay
- AE El-Hadary
- DK Das
- EA Elsherbiny
- EA Elsherbiny
- EM Yahia
- G Bailén
- G Giuliano
- G Romanazzi
- H Gao
- JDLM Carvalho
- JE Dávila-Aviňa
- JMS Araújo
- JN Miller
- L Frusciante
- M Klein
- M Mushtaq
- MA Taher
- N Dasgupta
- NP Silva-Beltrán
- PD Fraser
- PJ Zapata
- R Casañas
- RC Ranveer
- S Oshima
- TM Chaouche
- TR Gopalakrishnan
- United States Departmente of Agricultre – USDA
- VM Munhoz
- W Kalt
- Y Dumas
- Y Li
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Reimagining US Colombianidades: Transnational subjectivities, cultural expressions, and political contestations
- Author
- A Aparicio
- A Aparicio
- A Chomsky
- A Dávila
- A Herrero-Olaizola
- A Ochoa Camacho
- AB Pobutsky
- AB Pobutsky
- AB Pobutsky
- AE Vigil
- AR López-Pedreros
- BC Williams
- C Bergquist
- C Escobar
- C Fojas
- C Fuchs
- C Medina
- C Milian
- C Rojas
- CM Sierra
- Cristina Beltrán
- D Bushnell
- D Hernández
- D Tubb
- E Bonilla-Silva
- EM Román
- F Aparicio
- F Safford
- FA Schaeffer
- I Morales
- IC Porras Contreras
- J Castaño
- J Flores
- J Harford Vargas
- J Harford Vargas
- J Harford Vargas
- J Heredia
- J Heredia
- J Hristov
- J Londoño
- J Rappaport
- J-B Meyer
- JA Vallejo
- Jennifer Harford Vargas
- Johana Londoño
- KS Gruesz
- L Aponte-Pares
- L Erickson-Schroth
- L García-Peña
- L Rincón
- LE Guarnizo
- LE Guarnizo
- LE Guarnizo
- Lina Rincón
- M Cardenas
- M Hames-García
- M Jones-Correa
- M Jones-Correa
- M LaRosa
- M Palacios
- M Roldán
- María Elena Cepeda
- ME Cepeda
- ME Cepeda
- ME Cepeda
- ME Cepeda
- ME Stanfield
- MR Nasser
- MR Nasser De La Torre
- N Kanellos
- N Naber
- N Trujillo-Pagán
- NP Appelbaum
- NV Celis
- P Banerjee
- P Engel
- P Fernandez-Kelly
- P Wade
- P Wade
- P Wade
- P Wade
- R Lippi-Green
- RL Mize
- RL Ortíz
- S Oboler
- S Oboler
- S Oboler
- S Paternostro
- S Paternostro
- S Torres-Saillant
- Z Liang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Natural bioactive substances for the control of food-borne viruses and contaminants in food
- Author
- A Barbiroli
- A Bhosle
- A Borges
- A Conte
- A Del Olmo
- A Duran
- A Fathima
- A Gamage
- A Kedia
- A Lucera
- A Prasad
- A Raju
- A Rivas
- A Syahidah
- A Valdés
- AB Howell
- AC Pinheiro
- ACV Solano
- AE Aguilar-González
- AR Madureira
- AR Sofy
- AS Hamid
- B Prakash
- B Waarts
- C Pastor
- C Plumed-ferrer
- CC Wen
- CL Cantrell
- CO Pérez-Alfonso
- D Cheng
- D Li
- D Li
- D Matijaševic
- D Sanver
- DA Youssef
- DG Newell
- DH D’Souza
- DH Gilling
- DO Cliver
- ER Adlard
- F He
- F Krichen
- F Shahidi
- G Singh
- G Yuan
- GA De Azeredo
- GR Gandhi
- GT Andevari
- GV Awolola
- H Aloui
- H Ikeura
- H Ishikawa
- H Jasim
- H Kinoshita
- H Kwon
- H Tsuchiya
- H Zhang
- H Zhang
- HDM Coutinho
- HDM Coutinho
- HJ Jang
- HMC Azeredo
- I Falcó
- I Fernández-Pan
- I Górniak
- I Palaska
- I Sánchez-Ortega
- J Achan
- J Gutierrez
- J Gutierrez
- J Hafsa
- J Lee
- JG Lopez-Reyes
- JH Lee
- JR Hwu
- K Pandey
- L Baert
- L Najafian
- L Najafian
- L Quintieri
- M Abbas
- M D’Ischia
- M Gilles
- M Hartmann
- M Iranshahi
- M Oh
- M Oh
- M Sienkiewicz
- M Sinigaglia
- M Viuda-Martos
- M Zaker
- ME Jacob
- MG Miranda-novales
- MK Bull
- MS Gurjar
- MS Rahman
- N Benkerroum
- N Chinnam
- N Goncharov
- N Reddy
- NP Silva-beltrán
- OJ Sharaibi
- P Avato
- P Cazón
- P Elizaquível
- P Gautret
- P Kidd
- P Rattanachaikunsopon
- P Umaraw
- P Wen
- PR Salgado
- Q Sun
- Q Zhang
- R Battistini
- R Davis
- R Davis
- R Gyawali
- R Hare
- R Irkin
- R Tserennadmid
- RK Ulrey
- S Bhatia
- S Ethelberg
- S Rawal
- S Saravanan
- S Thakur
- S Vandeplas
- SM Hassan
- SS Ferreira
- T Citarasu
- T Ismail
- T van Gerwe
- T Wu
- TE Petersen
- TG Villa
- TP Zomer
- V Kuete
- VB Maisuria
- W Randazzo
- WA Awad
- WC Reygaert
- WT Oliver
- X Su
- X Su
- X Zhang
- X Zheng
- Y Fang
- Y Liu
- Y Pan
- Y Wang
- Y Zhang
- Y Zhao
- YEWON Kim
- YS Cho
- Z Zhang
- ZL Zhou
- ZY Zhao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Aawsaj Y
- Abadia M
- Abad‐Gurumeta A
- Abad‐Motos A
- Abassy J
- Abate E
- Abbasov A
- Abbott D
- Abbott Tom EF
- Abdalla M
- Abdeldayem H
- Abdelkabir M
- Abdelkader Salama I
- Abdelkarim M
- Abdelsamed A
- Abdulfattah F
- Abdulwahed E
- Abdur‐Rahman LO
- Abel MK
- Abelevich A
- Abiyere H
- Aboelkassem Ibrahim A
- Aboharp Hasan Z
- Abou Chaar MK
- Abreu da Silva A
- Abubakar A
- Abukhalaf SA
- Abukhalaf Sadi
- Acebes García F
- Achalandabaso Boira M
- Acher A
- Acosta Mérida MA
- Acrich E
- Adam Essa Adam ME
- Adamina M
- Adamina Michel
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adeyeye A
- Adi H
- Adiamah A
- Adisa Adewale
- Afzal MF
- Agapov M
- Agarwal Arnav
- Aggarwal M
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguado López H
- Aguiar Júnior S
- Aguilar Gonzalez M
- Ahmed A
- Ahmed A
- Ahmed K
- Ahmed ME
- Ahmed Z
- Ahmeidat A
- Ahn JH
- Aiken T
- Aimé A
- Akalin M
- Akaydin E
- Akbas A
- Akhtar MA
- Akhtar N
- Akhter Rahman MM
- Akin E
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al ahmad F
- Al Asadi T
- Al Awwad S
- Al Ayed A
- Al Habes H
- Al Riyami S
- AL Sayed M
- Alaa S
- AlAamer O
- Aladeojebi A
- Alagoa Joao A
- Alakaloko Felix
- Alam F
- Alameer Ehab
- Alamri Alex
- Alanazi F
- Alawneh F
- Albaqami F
- Albertsmeier M
- Albertsmeier Markus
- Alcaide Matas F
- Alconchel F
- Alcázar JA
- Alderson Derek
- Aldokali N
- Aleksić L
- Alemanno G
- Alfaifi J
- Alfieri S
- Alfonso Garcia M
- Algallai M
- Alghamdi M
- Alghuliga A
- Alhamed A
- Alharthi M
- Alhassan N
- Ali karar AA
- Ali Sani S
- Ali AA
- Ali M
- Ali S
- Alishi Y
- Aliyeva Z
- Aljiffry M
- Alkadiki Ghadah Z
- Alkhateb S
- Allue M
- Almaadany Faraj S
- Almassaudi A
- Almeida AC
- Almeida JI
- Almeida‐Reis R
- Almezghwi H
- Almgla N
- Almond Max
- Alnumani T
- Alobaysi S
- Alobeed O
- Alonso de la Fuente N
- Alonso Poza A
- Alonso‐Lamberti L
- Alqahtani D
- Alqannas M
- Alrahawy M
- Alsayadi M
- Alsayadi R
- Alselaim N
- Alser Osaid
- Alshaar Muhammad
- Alshahrani A
- Alshahrani M
- Alshammari S
- Alshareea E
- Alshareef K
- Alsharif F
- Alshryda Sattar
- Alsoufi A
- Alsowaina K
- Altinel Y
- Altintoprak F
- Altom R
- Altomare DF
- Altomi I
- Alurralde C
- Alvarez E
- Alvarez MR
- Alvi A
- Alwarfly S
- Alyami M
- Alzaede S
- Alzahrani A
- Alzamanan M
- Alzeerelhouseini H I. A.
- Al‐Habsi R
- Al‐Kharashi E
- Al‐Khayal K
- Al‐Masri M
- Al‐Mohammad A
- Al‐Naggar H
- Al‐Najjar H
- Al‐Shehari M
- Al‐Slaibi I
- Amaral MJ
- Amira G
- Amorim E
- Amrani L
- Anania G
- Anastasi A
- Andrade R
- Angamuthu N
- Angelou D
- Angenete E
- Angoso‐Clavijo M
- Annamalai S
- Annessi V
- Annicchiarico A
- Anscomb N
- Antic A
- Antonakis P
- Antonopoulou MI
- Anula R
- Aparicio‐López D
- Aprile A
- Arab N
- Aremu M
- Arias‐Amézquita F
- Aribi N
- Aribi S
- Arican C
- Arigoni M
- Arikan AE
- Arkadopoulos N
- Arkani S
- Armao T
- Armatura G
- Arminio A
- Arnaud Alexis P
- Arora A
- Arrowsmith L
- Arslan K
- Arulanantham A
- Arumugam S
- Asaad P
- Ashcroft J
- Ashmore C
- Ashoush F
- Askari A
- Asqalan A
- Athanasakis E
- Athanasiou A
- Atherton R
- Attia D
- Augestad Knut Magne
- Avci EK
- Avellana R
- Aversano A
- Avlund T
- Awad S
- Ayasra F
- Ayasra Faris
- Ayasra Y
- Aydin C
- Ayloor Seshadri R
- Ayorinde J
- Aytac E
- Ayub B
- Ayubi A
- Ayyaz M
- Azab MA
- Azam M
- Azamat İF
- Azevedo C
- Azevedo J
- Azevedo José
- Azevedo P
- Azevedo P
- Azzam AY
- B L
- Babalola O
- Babar MS
- Baca B
- Bacarese‐Hamilton T
- Badahdah F
- Badra R
- Baena Sanfeliu E
- Bagraith K
- Baguley M
- Baig M
- Baili E
- Bailon‐Cuadrado M
- Baião JM
- Bajomo O
- Baker A
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- Bakkar B
- Bakmaz B
- Balabel M
- Balasubramaniam D
- Balconi A
- Baldari L
- Baldi C
- Baldini E
- Baldwin‐Smith R
- Bali K
- Balik E
- Ballabio M
- Ballouhey Q
- Baloyiannis I
- Bandara GBKD
- Bandovas JP
- Banfield D
- Bankhead‐Kendall Brittany K
- Banky B
- Baptista VH
- Barakat Awada J
- Barisic G
- Barker D
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- Bartalucci B
- Bartolini I
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- Baía C
- Bačić G
- Beamish AJ
- Beard David
- Beatson K
- Becker R
- Beech N
- Bekele K
- Bekheit M
- Belia F
- Belkhadir ZH
- Bellacci A
- Belli A
- Bello JO
- Bellolio F
- Bellora P
- Belluco C
- Beltrán de Heredia J
- Belvedere A
- Benavides Buleje JA
- Bendjemar L
- Benkabbou A
- Benson Ruth A
- Benson Ruth A
- Bergamini C
- Bergeat D
- Bernante P
- Bernasconi M
- Berselli M
- Bertelli G
- Bertolani E
- Besser N
- Beyer K
- Beyrne C
- Bezede C
- Bhalla A
- Bhama A
- Bhangu A
- Bhangu Aneel
- Bhangu Aneel A
- Bhangu Aneel A
- Bhasin S
- Bhat GA
- Bhat MA
- Bhatti MI
- Biala M
- Bianchini M
- Bianco F
- Bianco F
- Biel Juan Rey
- Bigam D
- Bigelow B
- Bilgin IA
- Bin Nasser A
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- Biondi A
- Birolo SL
- Bisagni P
- Bisset C
- Blackwell L
- Blanco‐Antona F
- Blanco‐Colino R
- Blanco‐Colino Ruth
- Blas Laina JL
- Blazquez Martin A
- Boal M
- Bodanese B
- Bodla AS
- Boeck M
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- Bondurri A
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- Borghi F
- Bork U
- Borroni G
- Bouchagier K
- Bouché PA
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- Boulton AJ
- Boutall A
- Boutros M
- Boutros M
- Bowman S
- Boyce R
- Boyd‐Carson H
- Bozkurt E
- Bozkurt MA
- Brachini G
- Bradulskis S
- Braham H
- Brar Amanpreet
- Bravo Infante R
- Bravo Ana Minaya
- Breen Kerry A
- Bretherton Chris
- Brewer H
- Bristow Rob
- Brito da Silva F
- Brixton G
- Brocklehurst M
- Bromage Steve
- Brown B
- Brown C
- Brown O
- Brown SR
- Brunelli Alessandro
- Brunt A
- Bruscino A
- Buarque Igor Lima
- Bueno Cañones AD
- Buerba GA
- Bukhari SI
- Bunni J
- Burahee A
- Burgan D
- Burke J
- Burke Joshua
- Buta M
- Butt U
- Buğra D
- Bywater Edward
- Bąk M
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- Cagigal Ortega EP
- Cagigas Fernandez C
- Caiado A
- Caiña Ruiz R
- Cakmak G
- Calabrò M
- Calikoglu F
- Calvo Espino P
- Camacho C
- Camara P
- Camarero Rodríguez E
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- Campagnaro T
- Campbell W
- Canas‐Martinez A
- Cano A
- Canonico G
- Canotilho R
- Cantalejo diaz M
- Capelli P
- Capezzuoli L
- Capitan‐Morales L
- Capkinoglu E
- Capolupo GT
- Capunge I
- Carabias‐Orgaz A
- Caram EL
- Carannante F
- Carbone F
- Carcoforo P
- Cardoso N
- Cardoso P
- Carissimi F
- Carrasco Prats M
- Caruana Edward J
- Caruana Edward J
- Carvalho Ferro C
- Carvello MM
- Casati M
- Cassinotti E
- Castro Borges F
- Castro Ruiz C
- Catalán Garza V
- Catena F
- Cato LD
- Cayetano Paniagua L
- Cecire J
- Ceelen W
- Cennet O
- Ceranic M
- Cerro Zaballos C
- Cervellera M
- Cervera I
- Cha DE
- Chaar Mohammad
- Chadha R
- Chakrabortee Sohini
- Chan E
- Chan E
- Chand M
- Charalabopoulos A
- Charre L
- Chase T
- Chaturvedi A
- Chaturvedi H
- Chatzikomnitsa P
- Chaudhry Daoud
- Chavarrias N
- Che jusoh A
- Chean CS
- Chebaro A
- Chen F
- Chen S
- Chern H
- Chessa A
- Cheung J
- Cheung LK
- Chevallay M
- Chia Z
- Chiappini A
- Chiarugi M
- Chinda J
- Chiozza M
- Chisthi M
- Chitul A
- Chiva Luis
- Chokshi R
- Cholewa H
- Choolani Bhojwani E
- Choong E
- Choudhry A
- Chowdhury A
- Chowdhury S
- Chowdri N
- Choynowski M
- Christensen P
- Christensen Peter
- Christidis P
- Christoforidis D
- Christou C
- Chrysos E
- Chumbinho B
- Chung E
- Chyau Patnaik S
- Cianflocca D
- Cicerchia PM
- Cintas Catena J
- Ciofic E
- Cirillo B
- Cirocchi N
- Ciubotaru C
- Clarizia G
- Claro M
- Clifford R
- Coccolini F
- Cocozza E
- Coffey JC
- Cohen Paul
- Colao García L
- Collera Ormazabal P
- Colletti G
- Colling K
- Colombari RC
- Colombo F
- Colquhoun Alexandra
- Colsa P
- Colvin HV
- Conesa A
- Confalonieri M
- Connelly T
- Consorti E
- Conti L
- Conti L
- Contis I
- Coomber E
- Coonar Aman S
- Cooper Z
- Corbellini C
- Cordera F
- Corless K
- Correa Bonito A
- Correia de Sá T
- Correia AM
- Corrigan M
- Corte Real J
- Cortes Murgueitio N
- Cortés‐Guiral D
- Cosimelli M
- Costa Santos D
- Costa M
- Costa MJMA
- Costanzi A
- Costeira B
- Costigan F
- Cotoia A
- Cotte E
- Coughlin P
- Cox Daniel
- Cozza V
- Craus‐Miguel A
- Creanga M
- Creavin B
- Cremonini C
- Crespo A
- Crichton A
- Cristian D
- Cros B
- Crugnale AS
- Cuadrado‐García A
- Cukier M
- Cukier Moises
- Cullivan O
- Cuming T
- Cunha C
- Cunha MF
- Cunha Miguel F
- Cunha Miguel F
- Cunha R
- Cunningham RM
- Curl‐Roper T
- Curtis Martínez C
- Cvetkovic A
- Cétares C
- D Escolà
- D G
- Dainius E
- Dajani K
- Daliya P
- Daly A
- Danias N
- Daniels IR
- Davidson Giana H
- Davies E
- Davies M
- Davies RJ
- Davis H
- Dawson AC
- Dawson AC
- Dawson Brett E
- Day A
- De Andres Olabarria U
- De Andrés‐Asenjo B
- De Lacy FB
- De Lima RK
- De Lucia F
- De Manzoni Garberini A
- De Miguel Ardevines MDC
- De Nardi P
- De Palma G
- De Simone V
- De Sousa X
- De Toma G
- De Troia A
- De Vincenti R
- Dean H
- Deirino A
- Del valle E
- Delgado Búrdalo L
- Delimpalta C
- Delinasios G
- Dell A
- Della Giustina E
- Dellaportas D
- Delrio P
- Demetriades Andreas K
- Demir H
- Demirli Atici S
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- Ławnicka A
- Žatecký J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis
- Author
- Aarts E
- Abbas Z
- Abburu S
- Abd Ghaffar Mk
- Abdelgalil R
- Abdelhadi M
- Abdikadir Hr
- Abdulmajid A
- Abdulrahman N
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- Calisgan B
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- Raina V
- Rajan N
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- Rakhimov I
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- Ramana A
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- Raurich-Leandro J
- Raut P
- Reakes T
- Realis Luc A
- Redgrave Na
- Redmond A
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- Sandhu Kk
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- Sapci I
- Saraceno F
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- Seneviratne N
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- Yildirim N
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- Yildiz T
- Yilmaz I
- Yilmaz M
- Yilmaz S
- Yilmaz T
- Yim N
- Yoganathan S
- Yong Cs
- Yong N
- Yoruk I
- Yousif A
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- Yuksel A
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- Yurekli Am
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- Ziff O
- Zigiotto D
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- Zimmerman D
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- Zuhair M
- Örhalmi J
- Özkan Bb
- Šimáčková B
- Široká M
- Žebrák R
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien\u2013Dindo Grades III\u2013V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49\u20132.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46\u20130.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease