5,561 research outputs found
Concept to convert electrical power
Moving fluid conductor transforms electrical power from one voltage to another. The electrically conductive fluid acts as a coupling medium between or among multiple electromagnetic fields producing the conversion
The QCD equation of state at finite density from analytical continuation
We determine the equation of state of QCD at finite chemical potential, to
order , for a system of 2+1 quark flavors. The simulations are
performed at the physical mass for the light and strange quarks on several
lattice spacings; the results are continuum extrapolated using lattices of up
to temporal resolution. The QCD pressure and interaction measure are
calculated along the isentropic trajectories in the plane
corresponding to the RHIC Beam Energy Scan collision energies. Their behavior
is determined through analytic continuation from imaginary chemical potentials
of the baryonic density. We also determine the Taylor expansion coefficients
around from the simulations at imaginary chemical potentials.
Strangeness neutrality and charge conservation are imposed, to match the
experimental conditions.Comment: 5 pages, 4 figure
A Guide to Cannabis Virology: From the Virome Investigation to the Development of Viral Biotechnological Tools
Cannabis sativa cultivation is experiencing a period of renewed interest due to the new opportunities for its use in different sectors including food, techno-industrial, construction, pharmaceutical and medical, cosmetics, and textiles. Moreover, its properties as a carbon sequestrator and soil improver make it suitable for sustainable agriculture and climate change mitigation strategies. The increase in cannabis cultivation is generating conditions for the spread of new pathogens. While cannabis fungal and bacterial diseases are better known and characterized, viral infections have historically been less investigated. Many viral infection reports on cannabis have recently been released, highlighting the increasing threat and spread of known and unknown viruses. However, the available information on these pathogens is still incomplete and fragmentary, and it is therefore useful to organize it into a single structured document to provide guidance to growers, breeders, and academic researchers. This review aims to present the historical excursus of cannabis virology, from the pioneering descriptions of virus-like symptoms in the 1940s/50s to the most recent high-throughput sequencing reports. Each of these viruses detected in cannabis will be categorized with an increasing degree of threat according to its potential risk to the crop. Lastly, the development of viral vectors for functional genetics studies will be described, revealing how cannabis virology is evolving not only for the characterization of its virome but also for the development of biotechnological tools for the genetic improvement of this crop
MicroRNAs (miRNAs) and Long Non-Coding RNAs (lncRNAs) as New Tools for Cancer Therapy: First Steps from Bench to Bedside.
Non-coding RNAs represent a significant proportion of the human genome. After having been considered as 'junk' for a long time, non-coding RNAs are now well established as playing important roles in maintaining cellular homeostasis and functions. Some non-coding RNAs show cell- and tissue-specific expression patterns and are specifically deregulated under pathological conditions (e.g. cancer). Therefore, non-coding RNAs have been extensively studied as potential biomarkers in the context of different diseases with a focus on microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) for several years. Since their discovery, miRNAs have attracted more attention than lncRNAs in research studies; however, both families of non-coding RNAs have been established to play an important role in gene expression control, either as transcriptional or post-transcriptional regulators. Both miRNAs and lncRNAs can regulate key genes involved in the development of cancer, thus influencing tumour growth, invasion, and metastasis by increasing the activation of oncogenic pathways and limiting the expression of tumour suppressors. Furthermore, miRNAs and lncRNAs are also emerging as important mediators in drug-sensitivity and drug-resistance mechanisms. In the light of these premises, a number of pre-clinical and early clinical studies are exploring the potential of non-coding RNAs as new therapeutics. The aim of this review is to summarise the latest knowledge of the use of miRNAs and lncRNAs as therapeutic tools for cancer treatment
Wrapping corrections, reciprocity and BFKL beyond the sl(2) subsector in N=4 SYM
We consider N=4 SYM and a class of spin N, length-3, twist operators beyond
the well studied sl(2) subsector. They can be identified at one-loop with three
gluon operators. At strong coupling, they are associated with spinning strings
with two spins in AdS5. We exploit the Y-system to compute the leading
weak-coupling four loop wrapping correction to their anomalous dimension. The
result is written in closed form as a function of the spin N. We combine the
wrapping correction with the known four-loop asymptotic Bethe Ansatz
contribution and analyze special limits in the spin N. In particular, at large
N, we prove that a generalized Gribov-Lipatov reciprocity holds. At negative
unphysical spin, we present a simple BFKL-like equation predicting the
rightmost leading poles.Comment: 18 page
QGP Susceptibilities from PNJL Model
An improved version of the PNJL model is used to calculate various
thermodynamical quantities, {\it viz.}, quark number susceptibility, isospin
susceptibility, specific heat, speed of sound and conformal measure. Comparison
with Lattice data is found to be encouraging.Comment: 4 pages, 2 figures, poster presented at Quark Matter'0
Design and Vertical Tests of SPS-series Double-Quarter Wave (DQW) Cavity Prototypes for the HL-LHC Crab Cavity System
Crab crossing is essential for high-luminosity colliders. The High Luminosity
Large Hadron Collider (HL-LHC) will equip one of its Interaction Points (IP1)
with Double-Quarter Wave (DQW) crab cavities. A DQW cavity is a new generation
of deflecting RF cavities that stands out for its compactness and broad
frequency separation between fundamental and first high-order modes. The
deflecting kick is provided by its fundamental mode. Each HL-LHC DQW cavity
shall provide a nominal deflecting voltage of 3.4 MV, although up to 5.0 MV may
be required. A Proof-of-Principle (PoP) DQW cavity was limited by quench at 4.6
MV. This paper describes a new, highly optimized cavity, designated DQW
SPS-series, which satisfies dimensional, cryogenic, manufacturing and impedance
requirements for beam tests at SPS and operation in LHC. Two prototypes of this
DQW SPS-series were fabricated by US industry and cold tested after following
conventional SRF surface treatment. Both units outperformed the PoP cavity,
reaching a deflecting voltage of 5.3-5.9 MV. This voltage - the highest reached
by a DQW cavity - is well beyond the nominal voltage of 3.4 MV and may even
operate at the ultimate voltage of 5.0MVwith sufficient margin. This paper
covers fabrication, surface preparation and cryogenic RF test results and
implications
Nonlocal SU(3) chiral quark models at finite temperature: the role of the Polyakov loop
We analyze the role played by the Polyakov loop in the description of the
chiral phase transition within the framework of nonlocal SU(3) chiral models
with flavor mixing. We show that its presence provides a substantial
enhancement of the predicted critical temperature, bringing it to a better
agreement with the most recent results of lattice calculations.Comment: 9 pages, 1 figur
Do dogs and cats passively carry sars-cov-2 on hair and pads?
The epidemiological role of domestic animals in the spread and transmission of SARS-CoV-2 to humans has been investigated in recent reports, but some aspects need to be further clarified. To date, only in rare cases have dogs and cats living with COVID-19 patients been found to harbour SARS-CoV-2, with no evidence of pet-to-human transmission. The aim of the present study was to verify whether dogs and cats act as passive mechanical carriers of SARS-CoV-2 when they live in close contact with COVID-19 patients. Cutaneous and interdigital swabs collected from 48 dogs and 15 cats owned by COVID-19 patients were tested for SARS-CoV-2 by qRT-PCR. The time elapsed between owner swab positivity and sample collection from pets ranged from 1 to 72 days, with a median time of 23 days for dogs and 39 days for cats. All samples tested negative, suggesting that pets do not passively carry SARS-CoV-2 on their hair and pads, and thus they likely do not play an important role in the virus transmission to humans. This data may contribute to confirming that the direct contact with the hair and pads of pets does not represent a route for the transmission of SARS-CoV-2
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