43,734 research outputs found
Treatment dilemmas in a young man presenting with narcolepsy and psychotic symptoms.
Psychotic features can be present in both narcolepsy and psychosis, which can result in challenges in diagnosis and management. The prevalence of both conditions is low and the reports in young people are scarce. Our report illustrates the relevance of a thorough differential diagnosis as well as the need to explore treatment avenues based on the evidence available for both narcolepsy and psychosis symptoms to try and maximise the therapeutic impact
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Agent-based Simulation of Open Source Software Evolution
We present an agent-based simulation model of open source software (OSS). To our knowledge, this is the first model of OSS evolution that includes four significant factors: productivity limited by the complexity of software modules, the software's fitness for purpose, the motivation of developers, and the role of users in defining requirements. The model was evaluated by comparing the simulated results against four measures of software evolution (system size, proportion of highly complex modules, level of complexity control work, and distribution of changes) for four large OSS systems. The simulated results resembled all the observed data, including alternating periods of growth and stagnation. The fidelity of the model suggests that the factors included here have significant effects on the evolution of OSS systems
Investigations in space-related molecular biology
Improved instrumentation and preparation techniques for high resolution, high voltage cryo-electron microscopic and diffraction studies on terrestrial and extraterrestrial specimens are reported. Computer correlated ultrastructural and biochemical work on hydrated and dried cell membranes and related biological systems provided information on membrane organization, ice crystal formation and ordered water, RNA virus linked to cancer, lunar rock samples, and organometallic superconducting compounds. Apollo 11, 12, 14, and 15 specimens were analyze
The far-IR spectrum of Sagittarius B2 region: Extended molecular absorption, photodissociation and photoionization
We present large scale 9'x 27'(25 pc x 70 pc) far-IR observations around Sgr
B2 using the Long-wavelength spectrometer (LWS) on board the Infrared Space
Observatory (ISO). The spectra are dominated by the strong continuum emission
of dust, the widespread molecular absorption of light hydrides (OH, CH and H2O)
and the fine structure lines of [NII], [NIII], [OIII], [CII] and [OI]. The
molecular richness in the outer layers of Sgr B2 is probed by the ISO-LWS
Fabry-Perot (35 km s^-1) detections towards Sgr B2(M), where more that 70 lines
from 15 molecular and atomic species are observed at high signal to noise
ratio.Comment: 46 pages, 10 figures, 5 tables, accepted in ApJ part I. (Figs. 1, 2,
3, 9 and 10 have been bitmapped to low resolution
Quantum spin Hall phase in multilayer graphene
The so called quantum spin Hall phase is a topologically non trivial
insulating phase that is predicted to appear in graphene and graphene-like
systems. In this work we address the question of whether this topological
property persists in multilayered systems. We consider two situations: purely
multilayer graphene and heterostructures where graphene is encapsulated by
trivial insulators with a strong spin-orbit coupling. We use a four orbital
tight-binding model that includes the full atomic spin-orbit coupling and we
calculate the topological invariant of the bulk states as well as the
edge states of semi-infinite crystals with armchair termination. For
homogeneous multilayers we find that even when the spin-orbit interaction opens
a gap for all the possible stackings, only those with odd number of layers host
gapless edge states while those with even number of layers are trivial
insulators. For the heterostructures where graphene is encapsulated by trivial
insulators, it turns out that the interlayer coupling is able to induce a
topological gap whose size is controlled by the spin-orbit coupling of the
encapsulating materials, indicating that the quantum spin Hall phase can be
induced by proximity to trivial insulators.Comment: 7 pages, 6 figure
Cryogenic MMIC low noise amplifiers
Monolithic (MMIC) and discrete transistor (MIC) low noise amplifiers are compared on the basis of performance, cost, and reliability. The need for cryogenic LNA’s for future large microwave arrays for radio astronomy is briefly discussed and data is presented on a prototype LNA for the 1 to 10 GHz range along with a very wideband LNA for the 1 to 60 GHz range. A table of MMIC LNA and mixer designs under development for the frequencies up to 210 GHz is reported and data on cryogenic amplifiers in the 85 to 115 GHz is reviewed. The current status of the topics of transconductance fluctuations and cryogenic noise modeling will be briefly summarized
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