Kaehler forms and cosmological solutions in type II supergravities

We consider cosmological solutions to type II supergravity theories where the spacetime is split into a FRW universe and a K\"ahler space, which may be taken to be Calabi-Yau. The various 2-forms present in the theories are taken to be proportional to the K\"ahler form associated to the K\"ahler space.Comment: 6 pages, LaTeX2

Performance-based financing as a health system reform : mapping the key dimensions for monitoring and evaluation

Peer reviewedPublisher PD

Compactifications with S-Duality Twists

We consider generalised Scherk Schwarz reductions of supergravity and superstring theories with twists by electromagnetic dualities that are symmetries of the equations of motion but not of the action, such as the S-duality of D=4, N=4 super-Yang-Mills coupled to supergravity. The reduction cannot be done on the action itself, but must be done either on the field equations or on a duality invariant form of the action, such as one in the doubled formalism in which potentials are introduced for both electric and magnetic fields. The resulting theory in odd-dimensions has massive form fields satisfying a self-duality condition $dA \sim m*A$. We construct such theories in D=3,5,7.Comment: Latex, 26 pages. References adde

Pet-related bacterial zoonotic infections:Three cases of severe infections in the immunocompromised host

Pets can have many positive effects on their owners. However, close contact with pets offers optimal conditions for transmission of micro-organisms. Especially immunocompromised patients are at risk for zoonotic infections. Here we describe the diagnosis, microbiology and treatment of three patients with severe zoonotic infections with Helicobacter canis, Pasteurella multocida and Capnocytophaga canimorsus. With this case report we would like to emphasize the importance of awareness for pet-related zoonotic infections in immunocompromised patients

Tetranucleotide and Low Microsatellite Instability Are Inversely Associated with the CpG Island Methylator Phenotype in Colorectal Cancer

MSH3 gene or protein deficiency or loss-of-function in colorectal cancer can cause a DNA mismatch repair defect known as “elevated microsatellite alterations at selected tetranucleotide repeats” (EMAST). A high percentage of MSI-H tumors exhibit EMAST, while MSI-L is also linked with EMAST. However, the distribution of CpG island methylator phenotype (CIMP) within the EMAST spectrum is not known. Five tetranucleotide repeat and five MSI markers were used to classify 100 sporadic colorectal tumours for EMAST, MSI-H and MSI-L according to the number of unstable markers detected. Promoter methylation was determined using methylation-specific PCR for MSH3, MCC, CDKN2A (p16) and five CIMP marker genes. EMAST was found in 55% of sporadic colorectal carcinomas. Carcinomas with only one positive marker (EMAST-1/5, 26%) were associated with advanced tumour stage, increased lymph node metastasis, MSI-L and lack of CIMP-H. EMAST-2/5 (16%) carcinomas displayed some methylation but MSI was rare. Carcinomas with ≥3 positive EMAST markers (13%) were more likely to have a proximal colon location and be MSI-H and CIMP-H. Our study suggests that EMAST/MSI-L is a valuable prognostic and predictive marker for colorectal carcinomas that do not display the high methylation phenotype CIMP-H

Assessing Communities of Practice in health policy : A conceptual framework as a first step towards empirical research

Peer reviewe

Domain Walls and the Creation of Strings

The phenomenon of creation of strings, occurring when particles pass through a domain wall and related to the Hanany-Witten effect via dualities, is discussed in ten and nine dimensions. We consider both the particle actions in massive backgrounds as well as the 1/4-supersymmetric particle-string-domain wall supergravity solutions and discuss their physical interpretation. In 10D we discuss the D0-F1-D8 system in massive IIA theory while in 9D the SL(2,R)-generalisation is constructed. It consists of (p,q)-particles, (r,s)-strings and the double domain wall solution of the three different 9D gauged supergravities where a subgroup of SL(2,R) is gauged.Comment: v1: 22 pages, 3 figures. v2: footnote and reference adde

All solutions of the localization equations for N=2 quantum black hole entropy

We find the most general bosonic solution to the localization equations describing the contributions to the quantum entropy of supersymmetric black holes in four-dimensional N=2 supergravity coupled to n_v vector multiplets. This requires the analysis of the BPS equations of the corresponding off-shell supergravity (including fluctuations of the auxiliary fields) with AdS2 \times S2 attractor boundary conditions. Our work completes and extends the results of arXiv:1012.0265 that were obtained for the vector multiplet sector, to include the fluctuations of all the fields of the off-shell supergravity. We find that, when the auxiliary SU(2) gauge field strength vanishes, the most general supersymmetric configuration preserving four supercharges is labelled by n_v+1 real parameters corresponding to the excitations of the conformal mode of the graviton and the scalars of the n_v vector multiplets. In the general case, the localization manifold is labelled by an additional SU(2) triplet of one-forms and a scalar function.Comment: 27 page

New Formulations of D=10 Supersymmetry and D8-O8 Domain Walls

We discuss a generalized form of IIA/IIB supergravity depending on all R-R potentials C^(p) (p=0,1,...,9) as the effective field theory of Type IIA/IIB superstring theory. For the IIA case we explicitly break this R-R democracy to either p=5 which allows us to write a new bulk action that can be coupled to N=1 supersymmetric brane actions. The case of 8-branes is studied in detail using the new bulk & brane action. The supersymmetric negative tension branes without matter excitations can be viewed as orientifolds in the effective action. These D8-branes and O8-planes are fundamental in Type I' string theory. A BPS 8-brane solution is given which satisfies the jump conditions on the wall. It implies a quantization of the mass parameter in string units. Also we find a maximal distance between the two walls, depending on the string coupling and the mass parameter. We derive the same results via supersymmetric flow equations.Comment: 30 pages, 2nd version: reference adde

XPAD: pixel detector for material sciences

Currently available 2D detectors do not make full use of the high flux and high brilliance of third generation synchrotron sources. The XPAD prototype, using active pixels, has been developed to fulfil the needs of materials science scattering experiments. At the time, its prototype is build of eight modules of eight chips. The threshold calibration of /spl ap/4 10/sup 4/ pixels is discussed. Applications to powder diffraction or SAXS experiments prove that it allows to record high quality data