Perbincangan Mengenai Hukuman Mati Terkait Kasus Bali Nine Dan Mary Jane Dalam Situs Jejaring Sosial Twitter

Twitter telah menjadi alat atau media komunikasi yang sangat populer diantara para pengguna Internet. Melalui Twitter, penggunanya dapat berbagi cerita hidup mereka sehari-hari, melakukan perbincangan dengan pengguna lain dan juga mengekspresikan pendapat mereka. Twitter juga dapat dilihat sebagai sebuah wadah untuk melakukan perbincangan politik dan isu-isu publik. Oleh karena itu, peran Twitter terkait partisipasi publik, kampanye, dan pembentukan opini publik kini semakin diperhitungkan (Jungherr, 2015). Fokus penelitian ini tentang perbincangan para pengguna Twitter di Indonesia mengenai peristiwa hukuman mati kasus narkoba Bali Nine dan Mary Jane. Penelitian ini bertujuan untuk mengetahui apa ragam perbincangan yang terjadi di antara para pengguna Twitter Indonesia terkait kasus hukuman mati tersebut, apa argumen yang muncul terkait penolakan maupun dukungan terhadap isu hukuman mati, dan juga siapa saja Twitter Influencer yang berperan dalam isu ini. DOI: 10.24198/jkk.vol4n1.

Bisnis Vlogging dalam Industri Media Digital di Indonesia

This study explores the phenomenon of Vlogger as a new business in the digital media industry in Indonesia. Vlogger refer to social media users who regularly upload a variety of video content with various themes. We used case study to describe and analyze Youtube\u27s significant role in managing Vlogger communities, and also design support systems to make the communities growth and sustainable. We also explore Vlogger role as Online Influencer. This study is expected to be one of the references related to Vlogger phenomenon in the context of digital media studies in Indonesia

Genetic pre-participation screening in selected athletes: a new tool for the prevention of sudden cardiac death?

Sudden cardiac death (SCD) of athletes is a topical issue. “Borderline cardiac abnormalities”, which occur in ~2% of elite male athletes, may result in SCD, which may have a genetic base. Genetic analysis may help identify pathological cardiac abnormalities. We performed phenotype-guided genetic analysis in athletes who, pre-participation, showed ECG and/or echo “borderline” abnormalities, to discriminate subjects at a greater risk of SCD. Methods: We studied 24 elite athletes referred by the National Federation of Olympic sports; and 25 subjects seeking eligibility to practice agonistic sport referred by the Osservatorio Epidemiologico della Medicina dello Sport della Regione Campania. Inclusion criteria: a) ECG repolarization borderline abnormalities; b) benign ventricular arrhythmias; c) left ventricular wall thickness in the grey zone of physiology versus pathology (max wall thickness 12-15 mm in females; 13-16 mm in males). Based on the suspected phenotype, we screened subjects for the LMNA gene, for 8 sarcomeric genes, 5 desmosomal genes, and cardiac calcium, sodium and potassium channel disease genes. Results: Genetic analysis was completed in 37/49 athletes, 22 competitive and 27 non-competitive athletes, showing “borderline” clinical markers suggestive of hypertrophic cardiomyopathy (HCM,n. 24), dilated cardiomyopathy (n. 4), arrhythmogenic right ventricular dysplasia/cathecholaminergic polymorphic ventricular tachycardia (ARVD/CPVT, n. 11), long QT syndrome (LQTS, n. 4), sick sinus syndrome (SSS, n. 5), Brugada syndrome (BrS, n. 1). We identifyed 11 mutations in 9 athletes (an ARVD athlete was compound heterozygote for the PKP2 gene and an HCM athlete was double heterozygote for the MYBPC3 and TNNT2 genes): 3 known mutations related to LQTS, HCM and ARVD, respectively, and 8 novel mutations, located in the SCN5A, RyR2, PKP2, MYBPC3 and ACTC1 genes. The new mutations were absent in ~800 normal chromosomes and were predicted “probably damaging” by in silico analysis. Patch clamp analysis in channelopathies indicated for some mutation abnormal biophysical behavior of the corresponding mutant protein. Conclusion: Genetic analysis may help distinguish between physiology and pathology in athletes with clinically suspected heart disease

The Birmingham Boron Neutron Capture Therapy (BNCT) project : developments towards selective internal particle therapy

This paper will review progress on two aspects of the Birmingham BNCT project. Firstly on evaluation of the effects of high and low LET radiations when delivered simultaneously, and secondly on attempts to optimise delivery of the boron carrier compound BPA through pharmacokinetic studies. Simultaneous or non-simultaneous irradiations of V79 cells with alpha-particle and X-ray irradiations were performed. Alpha doses of 2 and 2.5 Gy were chosen and the impact on survival when delivered separately or simultaneously with variable doses of X-rays was evaluated. The pharmacokinetics of the delivery of a new formulation of BPA (BPA-mannitol) are being investigated in brain tumour patients through a study with 2 × 2 design featuring intravenous and intracarotid artery infusion of BPA, with or without a mannitol bolus. On the combined effect of low and high LET radiations, a synergistic effect was observed when alpha and X-ray doses are delivered simultaneously. The effect is only present at the 2.5 Gy alpha dose and is a very substantial effect on both the shape of the survival curve and the level of cell killing. This indicates that the alpha component may have the effect of inhibiting the repair of damage from the low LET radiation dose delivered simultaneously. On the pharmacokinetics of BPA, data on the first three cohorts indicate that bioavailability of BPA in brain ECF is increased substantially through the addition of a mannitol bolus, as well as by the use of intracarotid artery route of infusion. In both cases, for some patients the levels after infusion approach those seen in blood, whereas the ECF levels for intravenous infusion without mannitol are typically less than 10% of the blood values

The brain tumor experience from the relatives' perspective

Article describes the clinical optimization of uptake parameters of Boronophenylalanin

Pengembangan Konten Positif sebagai Bagian dari Gerakan Literasi Digital

Menjamurnya hoaks, misinformasi, disinformasi, hingga riuhnya konflik terkait isu politik identitas di media digital adalah contoh permasalahan yang coba diatasi oleh gerakan literasi digital di Indonesia. Salah satu strategi gerakan ini adalah dengan mengajak khalayak media, terutama anak muda untuk lebih banyak mengonsumsi, membuat, dan menyebarkan “konten positif”. Menariknya, hingga kini masih belum ada kajian yang mendefinisikan dan menggali lebih jauh pandangan serta persepsi anak muda itu sendiri terkait dengan konsep konten positif. Oleh karena itu, melalui penelitian ini, peneliti melakukan penggalian pemahaman konten positif pada anak muda dengan melakukan focus grup discussion kepada total 36 mahasiswa yang tersebar di empat perguruan tinggi negeri di Jawa Barat, yaitu Universitas Padjadjaran, Universitas Pendidikan Indonesia, Institut Pertanian Bogor, dan Universitas Singaperbangsa Karawang. Selain itu wawancara mendalam juga dilakukan kepada lima pakar terkait media digital yang terdiri dari perwakilan pihak akademisi, industri, maupun pemerintahan. Eksplorasi juga dilakukan pada pemberitaan terkait konten positif di media online. Penelitian ini memperlihatkan bahwa ide penyebaran konten positif sebagai bagian dari gerakan literasi digital masih belum dipahami anak muda dengan baik. Selain itu, tidak ada kesepahaman terkait definisi operasional dari konten positif. Informan menyatakan bahwa konten yang bernilai informatif, inspiratif, dan memiliki nilai guna, adalah contoh konten positif. Informan juga memiliki persepsi bahwa konten positif memiliki jumlah dan tingkat popularitas di bawah konten yang bersifat negatif. Mereka juga mengatakan bahwa masih diperlukan berbagai sosialisasi literasi digital dan konten positif agar ide ini dapat diterima dan disebarkan secara lebih luas

Polymeric nanostructured items electrospun on a cylindrical template: A simple procedure for their removal

Tubular structures, obtained by electrospinning on a rotating mandrel, are of interest for use as devices in medical and industrial applications. However, removal of electrospun tubes from the collecting mandrel has been a major problem and various techniques have been proposed, though having severe drawbacks. In our study, a method to safely remove electrospun tubes from a template mandrel (collector) is described. Before electrospinning, a copper wire is rolled up on the mandrel to form a helix, with the purpose of creating a gap between mandrel and electrospun tube once the wire is easily removed from the mandrel. Adopting the described methodology, uniform electrospun polymeric tubes can be easily removed from the mandrel. The procedure for fast rolling up of the wire on the rotating mandrel is also described