The QUIJOTE experiment: project overview and first results

QUIJOTE (Q-U-I JOint TEnerife) is a new polarimeter aimed to characterize the polarization of the Cosmic Microwave Background and other Galactic and extragalactic signals at medium and large angular scales in the frequency range 10-40 GHz. The multi-frequency (10-20~GHz) instrument, mounted on the first QUIJOTE telescope, saw first light on November 2012 from the Teide Observatory (2400~m a.s.l). During 2014 the second telescope has been installed at this observatory. A second instrument at 30~GHz will be ready for commissioning at this telescope during summer 2015, and a third additional instrument at 40~GHz is now being developed. These instruments will have nominal sensitivities to detect the B-mode polarization due to the primordial gravitational-wave component if the tensor-to-scalar ratio is larger than r=0.05.Comment: To appear in "Highlights of Spanish Astrophysics VIII", Proceedings of the XI Scientific Meeting of the Spanish Astronomical Society, Teruel, Spain (2014

The status of the Quijote multi-frequency instrument

The QUIJOTE-CMB project has been described in previous publications. Here we present the current status of the QUIJOTE multi-frequency instrument (MFI) with five separate polarimeters (providing 5 independent sky pixels): two which operate at 10-14 GHz, two which operate at 16-20 GHz, and a central polarimeter at 30 GHz. The optical arrangement includes 5 conical corrugated feedhorns staring into a dual reflector crossed-draconian system, which provides optimal cross-polarization properties (designed to be < -35 dB) and symmetric beams. Each horn feeds a novel cryogenic on-axis rotating polar modulator which can rotate at a speed of up to 1 Hz. The science driver for this first instrument is the characterization of the galactic emission. The polarimeters use the polar modulator to derive linear polar parameters Q, U and I and switch out various systematics. The detection system provides optimum sensitivity through 2 correlated and 2 total power channels. The system is calibrated using bright polarized celestial sources and through a secondary calibration source and antenna. The acquisition system, telescope control and housekeeping are all linked through a real-time gigabit Ethernet network. All communication, power and helium gas are passed through a central rotary joint. The time stamp is synchronized to a GPS time signal. The acquisition software is based on PLCs written in Beckhoffs TwinCat and ethercat. The user interface is written in LABVIEW. The status of the QUIJOTE MFI will be presented including pre-commissioning results and laboratory testing

Monitorización del consumo de sustancias de abuso legales e ilegales en España a través de las aguas residuales en el marco de la red ESAR-Net

Trabajo presentado en el 4th Congreso Internacional y XLIX Jornadas Nacionales de Socidrogalcohol - VIII Congreso Nacional Patología Bio-Psicosocial, celebrado en Tenerife del 06 al 08 de octubre de 2022

Sequential Assembly of Centromeric Proteins in Male Mouse Meiosis

The assembly of the mitotic centromere has been extensively studied in recent years, revealing the sequence and regulation of protein loading to this chromosome domain. However, few studies have analyzed centromere assembly during mammalian meiosis. This study specifically targets this approach on mouse spermatocytes. We have found that during prophase I, the proteins of the chromosomal passenger complex Borealin, INCENP, and Aurora-B load sequentially to the inner centromere before Shugoshin 2 and MCAK. The last proteins to be assembled are the outer kinetochore proteins BubR1 and CENP-E. All these proteins are not detected at the centromere during anaphase/telophase I and are then reloaded during interkinesis. The loading sequence of the analyzed proteins is similar during prophase I and interkinesis. These findings demonstrate that the interkinesis stage, regularly overlooked, is essential for centromere and kinetochore maturation and reorganization previous to the second meiotic division. We also demonstrate that Shugoshin 2 is necessary for the loading of MCAK at the inner centromere, but is dispensable for the loading of the outer kinetochore proteins BubR1 and CENP-E

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

A new in vivo screening paradigm to accelerate antimalarial drug discovery.

The emergence of resistance to available antimalarials requires the urgent development of new medicines. The recent disclosure of several thousand compounds active in vitro against the erythrocyte stage of Plasmodium falciparum has been a major breakthrou

Repertorio Americano. Edición del 22-OCTUBRE-1923

Antonio Caso, El heroísmo de los jóvenes, 65* N. Altamirano y Viera, Tengamos fe en la escuela, 65* Ramón Gómez de la Cerna, El zurcido de la siesta, 66* Sin autor, Repertorio Americano, 66* David Llovd George, La reacción antidemocrática, 67* R. Arévalo Martínez, Nada nuevo, 67* Sin autor, Dr. Constantino Herdocia, 68* Jesús Semprum, El impelismo de Mister Hughes, 69* Málaga Grenet, Mr. Charles Hughes, 69* J. C. Sotillo Picornell, La nueva diplomacia, 70* Sin autor, Dr. Alejandro Montero S., 70* Enrique Molina, Cuestiones latinoamericanas, 71* Sin autor, Cuestionario, 71* Sin autor, Dr. Odio de Granda, 71* Sin autor, Las pinturas decorativas del anfiteatro de la preparatoria, 72* Sin autor, Libros y folletos de ocasión a precios módicos, 72* Sin autor, La tierra sobre la bóveda, 73* Pedro Henríquez Ureña, Diego Rivera, 74* Gabriel Alomar, Los separatismos interiores, 74* Sin autor, A. Nin Frías, 75* Sin autor, El árbol y la historia de los pueblos, 75* J. García Monge, Solicítenos estas obras, Ánfora sedienta, 76* Sin autor, Cervecería Traube, 76* Sin autor, Botica Española, 77* Sin autor, Doctor Eduardo Montealegre, 77* Presbítero A. H. Pallais, Página lírica, 78* Sin autor, Esta casa dichosa, 79* Sin autor, Noticiario, 79* Sin autor, Ediciones del Repertorio Americano, 79* Sin autor, En lo sucesivo señores agentes y suscriptores de provincias sírvanse remitirme invariablemente los fondos bajo cubierta certificada o en forma de Giro, 80* Miguel de Unamuno, Asteriscos, 80* Sin autor, El convivio de los niños, 80