Detection of human papillomavirus DNA sequences in oral lesions using polymerase chain reaction

The purpose of the present study was to estimate the frequency of HPV DNA in four groups of oral lesions, including oral squamous cell carcinoma. Sixty paraffin-embedded oral tissue samples were examined for the presence of HPV DNAs using the PCR technique. These specimens were obtained from patients with oral squamous cell carcinoma (OSCC), leukoplakia, oral lichen planus (OLP), and pyogenic granuloma (PG). Consensus primers for L1 region (MY09 and MY11) and specific primers were used for detection of HPV DNA sequences in this study. we detected HPV DNA in 60% (9 out of 15) of OSCCs, 26.7% (4 out of 15) of leukoplakia, 13.3% (2 out of 15) of OLPs, and 6.7% (1 out of 15) of PGs. Statistical analysis showed that the prevalence of HPV in OSCC was significantly higher than other groups (P < 0.05). The frequency of HPV-16 and 18 detection in OSCC samples were 40% and 20%, respectively. The prevalence of these high risk HPVs was significantly higher in OSCC group (P < 0.05). The results of the present study show a successive increase of detection rate of HPV-16 and 18 DNAs from low level in samples of pyogenic granuloma and non-premalignant or questionably premalignant lesions of OLP to premalignant leukoplakia and to OSCC. © 2007 Tehran University of Medical Sciences. All rights reserved

A Comparative 6-Month Clinical Study of Acellular Dermal Matrix Allograft and Subepithelial Connective Tissue Graft for Root Coverage

Objective: Different surgical procedures have been proposed for the treatment of gingival recessions. The goal of this study was to compare the clinical results of gingival recession treatment using Subepithelial Connective Tissue Graft and an Acellular Dermal MatrixAllograft.Materials and Methods: The present study was performed on 5 patients with 9 bilateral Miller`s class I or II gingival recessions. This included 15 premolars and 3 canines. In each patient the teeth were randomly divided in two groups of test (ADMA) and control (SCTG).Clinical parameters including recession height (RH), recession width (RW), keratinized gingiva (KG), clinical attachment level (CAL) and probing depth (PD) were measured at baseline, 2, 4 and 6 months after surgery and data analysis was performed using the Wilcoxon signed rank test.Results: The mean changes (mm) from baseline to 6 months in SCTG and ADMA were 2.22±0.83 and 1.77±0.66 decrease in RH, 2.55±0.88 and 2.33±0.86 decrease in RW,1.44±0.88 and 2.0±1.11 increase in KG, 2.33±1.22 and 2.11±0.6 decrease in CAL and finally 0.22±0.66 and 0.33±0.7 decrease in PD, respectively. The differences in meanchanges were not significant between the two groups in any of the parameters. The percentage of root coverage was 85.7% and 71.1% for the control and test group,respectively. The changes from baseline to the 6 month visit were significant for both groups in all parameters but PD.Conclusion: Alloderm may be suggested as an acceptable substitute for connective tissue graft considering the root coverage effect and KG width increase

Metallogeny of Serpentinite-Hosted Magnetite Deposits : Hydrothermal Overgrowth on Chromite or Metamorphic Transformation of Chromite?

Peculiar and rare occurrences of serpentinite-hosted magnetite deposits with mineable sizes are found in the Mesozoic ophiolites of Greece (Skyros), Iran (Nain and Sabzevar) and Oman (Aniba). These deposits have diverse thickness (from a few centimeters up to 50 m) and length (2 to &gt;500 m). Magnetite ores show variable textures, including massive, nodular and banded ores, veins, net and fine-grained disseminations in serpentinites. Intriguingly, the investigated magnetite deposits can be mistaken for chromitite pods. Serpentinite-hosted magnetite deposits show three modes of occurrences including: (i) boulders strewn across the serpentinites (i.e. Skyros Island) (ii) ore bodies along the nonconformity contacts between serpentinites and limestones (i.e. Aniba); (iii) irregular and discontinuous trails of massive and semi-massive ore bodies within highly sheared serpentinite masses (i.e. Nain; Sabzevar). In all of these magnetite ore bodies, relicts of chromian spinel grains are occasionally enclosed in magnetite crystals. The chemistry of Cr-spinel relics found in these magnetite bodies are comparable to those of accessory Cr-spinels in the surrounding serpentinized peridotites. BSE images and elemental mapping revealed that magnetite occurs as a nucleation on chromian spinels but not being involved in reaction either with chromite or ferritchromite. Low-grade metamorphic transformation of chromite into Fe-chromite is documented along the cracks and fractures of a few chromite grains. Generally, magnetite has typical hydrothermal compositions, characterized by low Cr, V and Ti and high Mg and Mn. It is crucial to note that a few magnetite grains with metamorphic origin are characterized by high Cr and low Ti and Ni. The potential source of iron is essentially the Fe-rich olivine, We believe that multi-episodic serpentinization of peridotite systems at high fluid-rock ratios is the main process responsible for precipitation of magnetite at ore levels whereas low-grade metamorphic transformation of chromite to magnetite has minor contribution. Cumulative factors in generation of these deposits are modal volume of mantle olivine, peridotite composition, fluid chemistry, fluid-rock ratio, mechanisms of transportation and precipitation, structural controls such as cracks and shear zones

Comparison the self-concept and behavior in adolescents without criminal record with juvenile offenders

Background and aims: impermanent and negative self-concept , disrupts personal and social adjustment. in this study compared self-concept and behavior in adolescents without a history of juvenile criminal and offenders. Methods: The study was cross-sectional . 79 person from centers for Upbringing and correction via census sample and 120 person that with first group in regard to age-and sex- matched controls from Isfahan City were enrolled. The data collection instrument consisted of three sections include demographic information , self-concept and behavior questions. Statistic examination include T-test, Fisher and K2, were use for data analyzed . Results: The mean and standard deviation of self-Concept in offenders was 58/94±10/30 and Behavior was 62/26±28/81. Adolescents with no history of criminal record, self-concept score was 63/02±9/75 and Behavior was 84/66±15/22. Self-concept and behavior scores were significantly higher in the group with no criminal record (p<0/001). Conclusion: The results suggest that the Self-concept and Behavior of juvenile offenders is lower than adolescents with no criminal record. It is also considered demographic factors will affect the incidence of antisocial behavior . It seems psychologists and counselors to be working in these centers must training , counseling and therapy and correction techniques with consideration to the establishment of such anomalies

Interest in rhinoplasty and awareness about its postoperative complications among female high school students

Introduction: Rhinoplasty is a popular cosmetic surgical procedure. Informal statistics show that Iran has one of the highest rates of rhinoplasty in the world. However, rhinoplasty like any other surgery can have complications. Materials and Methods: In this cross-sectional study, 320 female students were selected by multistage cluster-stratified sampling from high schools in Kerman, Iran and each completed a questionnaire. Results: More than half of the students said they would like to undergo rhinoplasty. The main reasons for wanting rhinoplasty were beauty and because it is fashionable. However, more than half of the interested students did not know about the possible postoperative complications of rhinoplasty. There was no relation between interest in having rhinoplasty and parents' education, city of birth or economic status. Conclusion: Many teenagers are interested in having rhinoplasty in Iran. As the number of teenagers and young adults who choose to have cosmetic surgery increases, surgeons should consider their expectations, motivations and awareness of postoperative complications before surgery

The knowledge and the use of psychological skills of anger management skills at the bedside by the physicians and nurses of Jahrom University of Medical Sciences in 2013

Although all individuals could be exposed to the outburst of anger, a group of them are more at risk than others because of the nature of their work and responsibilities, that the physicians and nurses are placed in this group. In the field of psychology, different skills such as social protection systems, problem-solving skills, self-relaxation system, use of humor skills and communication and negotiation skills have been proposed to control anger. Given the importance of anger management in the prevention of job violence in the health environment and its impact on psychological health of psychiatrists and nurses and also the lack of information and research on the topic, this study aimed to study the knowledge and the use of psychological skills of anger management at the bedside by the physicians and nurses of Jahrom University of Medical Sciences.Methodology: This study is a cross-sectional and descriptive research, its studied sample included 259 general practitioners, specialists and nurses working in two general hospitals affiliated to Jahrom University of Medical Sciences. They were included in the study by the census method. The data was collected by the self-report method and two researcher-made questionnaires: a questionnaire of the knowledge of the psychological skills of anger management and a questionnaire of the use of anger management skills at the bedside and their validity (face and content) and reliability were examined before performing the research. Data analysis was performed with descriptive statistics (mean, frequency, percentage) using SPSS software.Results: The mean of the knowledge of the physicians and nurses of Jahrom University of Medical Sciences from the psychological skills of anger management was 30.2 (standard deviation is equal to 1.53) that based on the classification of the scores of related questionnaire, it was at a good level. Also, the results showed that the mean of the use of psychological skills of anger management at the bedside by the physicians and nurses working in Jahrom University of Medical Sciences was 39.54 (standard deviation is equal to 1.28) that based on the classification of the scores of related questionnaire, it was at a good level.Conclusion: According to the results, the knowledge and the use of psychological skills of anger management skills at the bedside by the physicians and nurses of Jahrom University of Medical Sciences were at the desired level, however, it is proposed to use other evaluation and assessment methods which have no limitations of self-report method in future studies.Keywords: anger management skill, nurses, physician

Measurements of scattering observables for the pdpd break-up reaction

High-precision measurements of the scattering observables such as cross sections and analyzing powers for the proton-deuteron elastic and break-up reactions have been performed at KVI in the last two decades and elsewhere to investigate various aspects of the three-nucleon force (3NF) effects simultaneously. In 2006 an experiment was performed to study these effects in $\vec{p}+d$ break-up reaction at 135 MeV with the detection system, Big Instrument for Nuclear polarization Analysis, BINA. BINA covers almost the entire kinematical phase space of the break-up reaction. The results are interpreted with the help of state-of-the-art Faddeev calculations and are partly presented in this contribution.Comment: Proceedings of 19th International IUPAP Conference on Few-Body Problems in Physics, Bonn University, 31.08 - 05.09.2009, Bonn, GERMAN

Understanding Humidity‐Enhanced Adhesion of Geckos: Deep Neural Network‐Assisted Multi‐Scale Molecular Modeling

A higher relative humidity leads to an increased sticking power of gecko feet to surfaces. The molecular mechanism responsible for this increase, however, is not clear. Capillary forces, water mediating keratin‐surface contacts and water‐induced softening of the keratin are proposed as candidates. In previous work, strong evidence for water mediation is found but indirect effects via increased flexibility are not completely ruled out. This article studies the latter hypothesis by a bottom‐up coarse‐grained mesoscale model of an entire gecko spatula designed without explicit water particles, so that capillary action and water‐mediation are excluded. The elasticity of this model is adjusted with a deep neural network to atomistic elastic constants, including water at different concentrations. Our results show clearly that on nanoscopic flat surfaces, the softening of keratin by water uptake cannot nearly account for the experimentally observed increase in gecko sticking power. Here, the dominant mechanism is the mediation of keratin‐surface contacts by intervening water molecules. This mechanism remains important on nanostructured surfaces. Here, however, a water‐induced increase of the keratin flexibility may enable the spatula to follow surface features smaller than itself and thereby increase the number of contacts with the surface. This leads to an appreciable but not dominant contribution to the humidity‐increased adhesion. Recently, by atomistic grand‐canonical molecular dynamics simulation, the room‐temperature isotherm is obtained for the sorption of water into gecko keratin, to the authors’ knowledge, the first such relation for any beta‐keratin. In this work, it relates the equilibrium water content of the keratin to the ambient relative humidity

Quantitative assessment of the impact of Mnemiopsis leidyi on the southern Caspian zooplankton structure during 1996-2010

After the arrival of the invasive species (Mnemiopsis leidyi) in the Caspian Sea (in 1999) significant changes have been occurred in the ecosystem. In the present study, the data concerning the period 1996 to 2010 (extracted from the relevant research projects) were analyzed. The period was classified into two phases, before and after the species invasion (1996 and 2001-2010). In our study, the impact of the invasive species on the structure of southern Caspian zooplankton communities was assessed during the period 2001-2010, quantitatively. The combination of abundance and distribution range of the species (ADR) during the period 2001-2009 and the year 2010 were evaluated as E (occurrence in high numbers in all localities) and D (occurrence in moderate numbers in all localities), respectively. Considering the obtained results, the year 2001, in which the relative biomass was more than 90 percent, could be considered as the expansion phase and the following years (2002-2010) as the adjustment phase. With regards to the loss of the keystone and some other native species after the invasion of M. leidyi (2001 to 2010), the impact of the invasive species on the structure of southern Caspian zooplankton communities was assessed as massive (C4)