An Unconventional Pathway: A Qualitative Inquiry Into the Experience of Racial Minority Transfer Students

Transfer students’ success is increasingly being discussed in higher education. A large population of transfer students includes racial minority, low-income, and first-generation college students. Due to the multiple layers of students’ identities, it has been difficult for educational leaders in institutions to grasp the essential elements needed to serve these students. As a result, this qualitative study contributes to this discussion and efforts to support the transfer student’s success. In this study, qualitative methods, including interviews with 14 students from 4-year universities and community colleges and a survey, were used to identify the steps and resources associated with supporting transfer students. The critical race theory framework served as the central lens to determine how racial factors played a vital key in the students’ post-transfer experience. The goal of this study was to ensure that the transfer students receive the essential resources and guidance from their institutions to have a successful transfer pathway to earning their degree

An Exploration in Social and Emotional Health of Vietnamese High School Students

Social and emotional health (SEH) aims to promote academic success and create school well-being. SEH has not been studied in Vietnam. This article focused on exploring the SEH of Vietnamese high school students because of the high-risk level in mental health that appeared in this group. The study was carried out using a qualitative case study approach to interviewing 74 students, 12 teachers, 7 school administrators, and 4 school counselors. We interpreted four features of SEH\u27s expression of Vietnamese students: (1) Confident but lack of individual perspectives, (2) Respectful but lack of listening and empathy in school relationships, (3) Balanced but lack of authentic perception of emotions and effective emotional management, (4) Satisfied but lack of sustainability and action. This study has broadened our understanding of external behaviours and current limitations in the young people’s SEH from their perspectives in a developing Southeast Asian country to promote positive psychological development in school-based prevention programs

The context of school-based cyberbullying prevention in Vietnamese public schools: A cross-sectional study

Cyberbullying is a form of violence that has been present in schools for a long time and negatively impacts the mental health of students. Different countries have different strategies for avoiding cyberbullying. However, research on school-based cyberbullying prevention is limited in Southeast Asian developing countries.  This study aims to explore the current implementation of school-based cyberbullying prevention in public schools in a developing country. The framework of prevention programs is based on three aspects: (1) Developing curricula on how to behave when being a victim of cyberbullying.  (2) Strengthening the students' skills to deal with cyberbullying. (3) Promulgating specific provisions in the legal document on handling cyberbullying. School-based cyberbullying prevention among students in public schools is currently a research gap because of the limitations in the management of students using the internet and educational policies. This is a cross-sectional study that surveyed 400 participants who are Vietnamese teachers, administrators and school psychologists. The results show that the limitations of school-based cyberbullying prevention for Vietnamese students include professional knowledge, practical experience and personnel in charge of this work.  This constraint has resulted in an upsurge in incidents of cyberbullying in Vietnam. The findings add to the important evidence on cyberbullying prevention in a developing country that is working to research and develop an appropriate school-based cyberbullying prevention strategy

Assay of Vitamin B6 (Pyridoxine Hydrochloride) Utilizing Isocratic Reversed Phase High Performance Liquid Chromatography

Aims: To demonstrate an analysis for vitamin B6 from commercial aqueous nutritional drinks and solid tablets, utilizing isocratic conditions with high performance liquid chromatography (HPLC) and UV detection at 290 nm. Study Design: Vitamin B6 in the form of pyridoxine hydrochloride is assayed by HPLC from various samples. Place and Duration of Study: Department of Chemistry, Durham Science Center, University of Nebraska, Omaha Nebraska from May to August 2016. Methodology: Utilizing a reversed-phase C-18 column with eluent solvent (19% ethanol, 77% water, 4% acetic acid), the samples were prepared in sample solvent (19% ethanol, 81% distilled water). Detection of vitamin B6 was accomplished at 290 nm. Analysis of samples was done following solubilizing in aqueous conditions having ethanol at 10% to 20% (v/v). Column pressure at 1900 psig, rise time 0.1 with flow rate 1.0 mL/minute. Elution peak for vitamin B6 occurred consistently at 1.6 minutes. Nutritional samples, aqueous samples, and solid pills were prepared in aqueous solvent with various levels of ethanol. Results: Levels of vitamin B6 detected were as low as 4.4029x10-5 molar to 7.8081x10-4 molar. Sensitivity for vitamin B6 was highest at 290 nm. Reverse phase isocratic conditions is shown to be effective for determination of vitamin B6 in aqueous based samples. Standard curves applied are highly linear in range from zero to 7.8081x10-4 molar (y = 112,521,145.5x + 2,818.6), having coefficient of determination (R2 = 0.9948) with very strong positive correlation coefficient (r= 0.9974). Percent recovery of vitamin ranged from 95% to 105%. Amounts of vitamin present in drinks from same manufacturer were consistent. Conclusion: Utilizing reversed phase column, isocratic solvent conditions with ethanol in water, and a UV detector set at 290 nm is effective for determination of vitamin B6. Ethanol-water solvent system is effective. Vitamin B6 was found in various amounts in nutritional drinks tested. Percent recovery of vitamin averaged 101% with a standard deviation of 2.4%. Pyridoxine hydrochloride was effectively assayed from aqueous samples, vitamin preparations, and vitamin tablets. The methodology presented in this study will be useful for quality control analysis for commercial production. Analysis methods for vitamin assay are a necessary objective to ensure quality control of commercial products and medicinal applications

El trauma de los niños vietnamitas que viven en familias incompletas

Children living in incomplete families have to suffer from more hardships than others including psychological trauma that could never be cured without safe approaches. In this paper, we used the Children Behavior Checklist (CBCL test) by Achenbach to initially filter the incidence of children in incomplete families with psychological trauma, the extent of childhood trauma, and the signs of trauma. Moreover, the Self-esteem scale of Toulouse was also utilized to investigate children's self-esteem and determine the impact of psychological trauma on the self-assessment of children. Based on these tools, the research conducted a correlation analysis of psychological trauma of children in incomplete families through indicators of awareness of, emotions with, and behaviors towards family and social life (self-evaluated by children). The results showed that there are differences in psychological trauma of children in terms of awareness, emotions, and behaviors. The differences allow for a better definition of children's causes, influences, and degrees of psychological trauma. This is the basis for proposing timely filtering solutions and effective psychological support measures for these children. Keywords: correlation analysis; signs of psychological trauma; children; incomplete family; Vietnam.Los niños que viven en familias incompletas tienen que sufrir más dificultades que otros, incluido el trauma psicológico que nunca podría curarse sin enfoques seguros. En este artículo, se utiliza la Lista de Verificación de Comportamiento Infantil (prueba CBCL) de Achenbach para filtrar inicialmente la incidencia de niños en familias incompletas con trauma psicológico, el alcance del trauma infantil y los signos de trauma. Además, la escala de autoestima de Toulouse también se utilizó para investigar la autoestima de los niños y determinar el impacto del trauma psicológico en la autoevaluación de los niños. Con base en estas herramientas, la investigación realizó un análisis de correlación del trauma psicológico de los niños en familias incompletas a través de indicadores de conciencia, emociones y comportamientos hacia la vida familiar y social (autoevaluados por los niños). Los resultados mostraron que existen diferencias en el trauma psicológico de los niños en términos de conciencia, emociones y comportamientos. Las diferencias permiten una mejor definición de las causas, influencias y grados de trauma psicológico de los niños. Esta es la base para proponer soluciones de filtrado oportunas y medidas de apoyo psicológico eficaces para estos niños. Palabras clave: análisis de correlación; signos de trauma psicológico; niños; familia incompleta; Vietnam

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY ASSAY FOR DETERMINATION OF MOXIFLOXACIN IN HUMAN PLASMA

A simple reversed phase HPLC method with UV detection has been successfully developed and validated for determination of moxifloxacin in human plasma. The sample pretreatment involves only single-step protein precipitation with tricloroacetic acid. Moxifloxacin was measured in plasma using a validated HPLC method with UV detector at 295 nm, C18 column (25cm×4.5mm, 5µm), a mixture of phosphate buffer pH 4.0 and acetonitrile (70:30, v/v) as mobile phase at a flow rate of 0.8 ml/min. Retention time of moxifloxacin was found to be 7.4 min. The mean recovery for the drug was obtained 97.30%. The calibration curve was linear over the concentration range of 0.3 to 25.0 µg/mL with coefficient correlation of 0.9991. This method was successfully applied for therapeutic drug monitoring

Differential Cytotoxicity of Curcumin-Loaded Micelles on Human Tumor and Stromal Cells

peer reviewedAlthough curcumin in the form of nanoparticles has been demonstrated as a potential anti-tumor compound, the impact of curcumin and nanocurcumin in vitro on normal cells and in vivo in animal models is largely unknown. This study evaluated the toxicity of curcumin-loaded micelles in vitro and in vivo on several tumor cell lines, primary stromal cells, and zebrafish embryos. Breast tumor cell line (MCF7) and stromal cells (human umbilical cord vein endothelial cells, human fibroblasts, and human umbilical cord-derived mesenchymal stem cells) were used in this study. A zebrafish embryotoxicity (FET) assay was conducted following the Organisation for Economic Co-operation and Development (OECD) Test 236. Compared to free curcumin, curcumin PM showed higher cytotoxicity to MCF7 cells in both monolayer culture and multicellular tumor spheroids. The curcumin-loaded micelles efficiently penetrated the MCF7 spheroids and induced apoptosis. The nanocurcumin reduced the viability and disturbed the function of stromal cells by suppressing cell migration and tube formation. The micelles demonstrated toxicity to the development of zebrafish embryos. Curcumin-loaded micelles demonstrated toxicity to both tumor and normal primary stromal cells and zebrafish embryos, indicating that the use of nanocurcumin in cancer treatment should be carefully investigated and controlled.3. Good health and well-bein

Prevalence and correlates of zinc deficiency in pregnant Vietnamese women in Ho Chi Minh City

Background: Although Vietnam is a region with a plant-based diet that has a high zinc deficiency, epidemiological data showing how this affects pregnant women are limited. This study explores the prevalence of zinc deficiency and possible correlates in pregnant Vietnamese women in Ho Chi Minh City. Methods: This was a crosssectional study conducted at a general hospital in Ho Chi Minh City, Vietnam. All pregnant women who came to their first antenatal care visit from November 2011 to June 2012 were recruited. Those taking a vitamin and/or mineral supplement were excluded. Serum zinc concentrations, determined by a standard colorimetric method, of 10.7 mol/L-17.5 mol/L (70.0 g/dL-114 g/dL) were classified as normal and under 10.7 mol/L (70.0 g/dL) as zinc deficient. Results: In total, 254 pregnant women were invited and 107 (42%) participated. The mean age of participants was 29 years, and mean gestational age was 10 weeks. Median zinc concentration in serum was 13.6 mol/L, and the prevalence of zinc deficiency was 29% (95% CI=21%-39%). The daily intake of a milk product supplement was the only significant correlate of zinc deficiency of the items investigated (adjusted OR=0.40, p=0.049). Discussion: This is the first study reporting that more than 25% of pregnant Vietnamese women in Ho Chi Minh City are zinc deficient. Further academic and clinical input is needed to confirm the scale of this neglected issue and to investigate the potential of milk product supplementation in this population

Spatiotemporal evolution of SARS-CoV-2 Alpha and Delta variants during large nationwide outbreak of COVID-19, Vietnam, 2021

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke