9 research outputs found
Heisenberg Symmetry and Collective Modes of One Dimensional Unitary Correlated Fermions
The correlated fermionic many-particle system, near infinite scattering
length, reveals an underlying Heisenberg symmetry in one dimension, as compared
to an symmetry in two dimensions. This facilitates an exact map from
the interacting to the non-interacting system, both with and without a harmonic
trap, and explains the short-distance scaling behavior of the wave-function.
Taking advantage of the phenomenological Calogero-Sutherland-type interaction,
motivated by the density functional approach, we connect the ground-state
energy shift, to many-body correlation effect. For the excited states, modes at
integral values of the harmonic frequency , are predicted in one
dimension, in contrast to the breathing modes with frequency in two
dimensions.Comment: 5 pages, revamped version for clarit
The right reforms? Health sector reforms and sexual and reproductive health services: training manual
FotocopiaÁrea de Salud, Economía y Socieda
Health sector reforms and sexual reproductive health services
Área de Salud, Economía y Socieda
Service accountability and community participation
Área de Salud, Economía y Socieda
Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017 : an analysis for the Global Burden of Disease Study 2017
CITATION: Troeger, C. E., et al. 2019. Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017 : an analysis for the Global Burden of Disease Study 2017. Lancet Respiratory Medicine, 7(1):69-89, doi:10.1016/S2213-2600(18)30496-X.The original publication is available at https://www.thelancet.comBackground: Although the burden of influenza is often discussed in the context of historical pandemics and the threat
of future pandemics, every year a substantial burden of lower respiratory tract infections (LRTIs) and other respiratory
conditions (like chronic obstructive pulmonary disease) are attributable to seasonal influenza. The Global Burden of
Disease Study (GBD) 2017 is a systematic scientific effort to quantify the health loss associated with a comprehensive
set of diseases and disabilities. In this Article, we focus on LRTIs that can be attributed to influenza.
Methods We modelled the LRTI incidence, hospitalisations, and mortality attributable to influenza for every country
and selected subnational locations by age and year from 1990 to 2017 as part of GBD 2017. We used a counterfactual
approach that first estimated the LRTI incidence, hospitalisations, and mortality and then attributed a fraction of
those outcomes to influenza.
Findings Influenza LRTI was responsible for an estimated 145 000 (95% uncertainty interval [UI] 99 000–200 000)
deaths among all ages in 2017. The influenza LRTI mortality rate was highest among adults older than 70 years
(16·4 deaths per 100 000 [95% UI 11·6–21·9]), and the highest rate among all ages was in eastern Europe (5·2 per
100 000 population [95% UI 3·5–7·2]). We estimated that influenza LRTIs accounted for 9 459 000 (95% UI
3 709 000–22 935 000) hospitalisations due to LRTIs and 81 536 000 hospital days (24 330 000–259 851 000). We
estimated that 11·5% (95% UI 10·0–12·9) of LRTI episodes were attributable to influenza, corresponding to 54 481 000
(38 465 000–73 864 000) episodes and 8 172 000 severe episodes (5 000 000–13 296 000).
Interpretation This comprehensive assessment of the burden of influenza LRTIs shows the substantial annual effect
of influenza on global health. Although preparedness planning will be important for potential pandemics, health loss
due to seasonal influenza LRTIs should not be overlooked, and vaccine use should be considered. Efforts to improve
influenza prevention measures are needed.https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(18)30496-X/fulltext#%20Publisher's versio
Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17
Abstract
Background: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage of ORS, RHF, and ORT (use of either ORS or RHF) in LMICs.
Methods: We used a Bayesian geostatistical model including 15 spatial covariates and data from 385 household surveys across 94 LMICs to estimate annual proportions of children younger than 5 years of age with diarrhoea who received ORS or RHF (or both) on continuous continent-wide surfaces in 2000–17, and aggregated results to policy-relevant administrative units. Additionally, we analysed geographical inequality in coverage across administrative units and estimated the number of diarrhoeal deaths averted by increased coverage over the study period. Uncertainty in the mean coverage estimates was calculated by taking 250 draws from the posterior joint distribution of the model and creating uncertainty intervals (UIs) with the 2·5th and 97·5th percentiles of those 250 draws.
Findings: While ORS use among children with diarrhoea increased in some countries from 2000 to 2017, coverage remained below 50% in the majority (62·6%; 12 417 of 19 823) of second administrative-level units and an estimated 6 519 000 children (95% UI 5 254 000–7 733 000) with diarrhoea were not treated with any form of ORT in 2017. Increases in ORS use corresponded with declines in RHF in many locations, resulting in relatively constant overall ORT coverage from 2000 to 2017. Although ORS was uniformly distributed subnationally in some countries, within-country geographical inequalities persisted in others; 11 countries had at least a 50% difference in one of their units compared with the country mean. Increases in ORS use over time were correlated with declines in RHF use and in diarrhoeal mortality in many locations, and an estimated 52 230 diarrhoeal deaths (36 910–68 860) were averted by scaling up of ORS coverage between 2000 and 2017. Finally, we identified key subnational areas in Colombia, Nigeria, and Sudan as examples of where diarrhoeal mortality remains higher than average, while ORS coverage remains lower than average.
Interpretation: To our knowledge, this study is the first to produce and map subnational estimates of ORS, RHF, and ORT coverage and attributable child diarrhoeal deaths across LMICs from 2000 to 2017, allowing for tracking progress over time. Our novel results, combined with detailed subnational estimates of diarrhoeal morbidity and mortality, can support subnational needs assessments aimed at furthering policy makers’ understanding of within-country disparities. Over 50 years after the discovery that led to this simple, cheap, and life-saving therapy, large gains in reducing mortality could still be made by reducing geographical inequalities in ORS coverage