Coherent backscattering of light by cold atoms: theory meets experiment

Coherent backscattering (CBS) of quasi-resonant light by cold atoms presents some specific features due to the internal structure of the atomic scatterers. We present the first quantitative comparison between the experimentally observed CBS cones and Monte-Carlo calculations which take into account the shape of the atomic cloud as well as the internal atomic structure.Comment: 5 pages, 3 figures, to appear in Eur. Phys. Let

Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort.

Objectives To determine whether progressive skin fibrosis is associated with visceral organ progression and mortality during follow-up in patients with diffuse cutaneous systemic sclerosis (dcSSc). Methods We evaluated patients from the European Scleroderma Trials and Research database with dcSSc, baseline modified Rodnan skin score (mRSS) ≥7, valid mRSS at 12±3 months after baseline and ≥1 annual follow-up visit. Progressive skin fibrosis was defined as an increase in mRSS >5 and ≥25% from baseline to 12±3 months. Outcomes were pulmonary, cardiovascular and renal progression, and all-cause death. Associations between skin progression and outcomes were evaluated by Kaplan-Meier survival analysis and multivariable Cox regression. Results Of 1021 included patients, 78 (7.6%) had progressive skin fibrosis (skin progressors). Median follow-up was 3.4 years. Survival analyses indicated that skin progressors had a significantly higher probability of FVC decline ≥10% (53.6% vs 34.4%; p<0.001) and all-cause death (15.4% vs 7.3%; p=0.003) than non-progressors. These significant associations were also found in subgroup analyses of patients with either low baseline mRSS (≤22/51) or short disease duration (≤15 months). In multivariable analyses, skin progression within 1 year was independently associated with FVC decline ≥10% (HR 1.79, 95% CI 1.20 to 2.65) and all-cause death (HR 2.58, 95% CI 1.31 to 5.09). Conclusions Progressive skin fibrosis within 1 year is associated with decline in lung function and worse survival in dcSSc during follow-up. These results confirm mRSS as a surrogate marker in dcSSc, which will be helpful for cohort enrichment in future trials and risk stratification in clinical practice

Resistive Inspiratory Muscle Training in People With Spinal Cord Injury During Inpatient Rehabilitation: A Randomized Controlled Trial

Background. People with spinal cord injury (SCI) may benefit from resistive inspiratory muscle training (RIMT). Current evidence is weak, and little is known about the effect on functional outcomes and long-term effects.Objective. The purpose of this study was to assess immediate and long-term effects of RIMT in people with SCI.Design. This was a single-blinded randomized controlled trial.Setting. The study was conducted at 4 specialized SCI units in the Netherlands.Patients. The study participants were 40 people with SCI (15 with motor complete tetraplegia, 16 with incomplete tetraplegia, 8 with motor complete paraplegia, and 1 with incomplete paraplegia) who had impaired pulmonary function and were admitted for initial inpatient rehabilitation.Intervention. Study participants were randomized to an RIMT group or a control group. All participants received usual rehabilitation care. In addition, participants in the intervention group performed RIMT with a threshold trainer.Measurements. Measurements were performed at baseline, after 8 weeks of intervention, 8 weeks later, and 1 year after discharge from inpatient rehabilitation. Primary outcome measures were: respiratory muscle function, lung volumes and flows, and perceived respiratory function. Secondary outcome measures concerned patient functioning, which included health-related quality of life, limitations in daily life due to respiratory problems, and respiratory complications.Results. During the intervention period, maximum inspiratory pressure (MIP) improved more in the RIMT group than in the control group (11.7 cm H2O, 95% confidence interval=4.3 to 19.0). At follow-up, this effect was no longer significant. No effect on other primary or secondary outcome measures was found except for an immediate effect on mental health.Limitations. The sample size was insufficient to study effects on respiratory complications.Conclusions. Resistive inspiratory muscle training has a positive short-term effect on inspiratory muscle function in people with SCI who have impaired pulmonary function during inpatient rehabilitation

Effects of directional microphone and adaptive multichannel noise reduction algorithm on cochlear implant performance

Although cochlear implant (CI) users have enjoyed good speech recognition in quiet, they still have difficulties understanding speech in noise. We conducted three experiments to determine whether a directional microphone and an adaptive multichannel noise reduction algorithm could enhance Cl performance in noise and whether Speech Transmission Index (STI) can be used to predict CI performance in various acoustic and signal processing conditions. In Experiment 1, CI users listened to speech in noise processed by 4 hearing aid settings: omni-directional microphone, omni-directional microphone plus noise reduction, directional microphone, and directional microphone plus noise reduction. The directional microphone significantly improved speech recognition in noise. Both directional microphone and noise reduction algorithm improved overall. preference. In Experiment 11, normal hearing individuals listened to the recorded speech produced by 4- or 8-channel CI simulations. The 8-channel simulation yielded similar speech recognition results as in Experiment 1, whereas the 4-channel simulation produced no significant difference among the 4 settings. In Experiment III, we examined the relationship between STIs and speech recognition. The results suggested that STI could predict actual and simulated Cl speech intelligibility with acoustic degradation and the directional microphone, but not the noise reduction algorithm. Implications for intelligibility enhancement are discussed. (c) 2006 Acoustical Society of America