1,545 research outputs found
Water Quality Monitoring and Constituent Load Estimation in the Upper White River Basin, 2009
The Arkansas Water Resources Center monitored water quality at seven sites in the Upper White River Basin during base flow conditions and storm events from July 1, 2009 through June 30, 2010. Water samples were collected manually with an alpha or Kemmerer style sampler and analyzed for nitrateânitrogen (NOââN), sulfate (SOâ), chloride (Clâ), soluble reactive phosphorus (SRP), total phosphorus (TP), dissolved ammonia (NHââN), total N (TN), total suspended solids (TSS), and turbidity. Physicoâchemical parameters were measured in field including pH, conductivity, water temperature, and dissolved oxygen concentration. The selected sites were all at established discharge monitoring stations maintained by the US Geological Survey, and constituent loads were determined using regression models between constituent concentrations, discharge, and seasonal factors to estimate daily loads, which were then summed to produce monthly, seasonal and annual load estimates. The constituent loads and annual flowâweighted concentrations for the 2009 calendar year are summarized in the table below, using the data collected in this study. The regression models were applied throughout the calendar year discharge record to estimate constituent loads for individual sites
Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapyinduced leukemia
Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive electrophiles, including metabolites of several chemotherapeutic agents, some of which are suspected human carcinogens. Functional polymorphisms exist in at least three genes that encode GSTs, including GSTM1, GSTT1, and GSTP1. We hypothesize, therefore, that polymorphisms in genes that encode GSTs alter susceptibility to chemotherapy-induced
carcinogenesis, specifically to therapy-related acute myeloid leukemia (t-AML), a devastating complication of long-term cancer survival. Elucidation of genetic determinants may help to identify individuals at increased risk of developing t-AML. To this end, we have examined 89 cases of t-AML, 420 cases of de novo AML, and
1,022 controls for polymorphisms in GSTM1, GSTT1, and GSTP1. Gene deletion of GSTM1 or GSTT1 was not specifically associated with susceptibility to t-AML. Individuals with at least one GSTP1 codon 105 Val allele were significantly over-represented in t-AML
cases compared with de novo AML cases [odds ratio (OR), 1.81; 95% confidence interval (CI), 1.11â2.94]. Moreover, relative to de novo AML, the GSTP1 codon 105 Val allele occurred more often among t-AML patients with prior exposure to chemotherapy (OR, 2.66; 95% CI, 1.39â5.09), particularly among those with prior exposure to known GSTP1 substrates (OR, 4.34; 95% CI, 1.43â13.20), and not
among those t-AML patients with prior exposure to radiotherapy alone (OR,1.01; 95% CI, 0.50â2.07). These data suggest that inheritance of at least one Val allele at GSTP1 codon 105 confers a significantly increased risk of developing t-AML after cytotoxic chemotherapy, but not after radiotherapy
Are Antiprotons Forever?
Up to one million antiprotons from a single LEAR spill have been captured in
a large Penning trap. Surprisingly, when the antiprotons are cooled to energies
significantly below 1 eV, the annihilation rate falls below background. Thus,
very long storage times for antiprotons have been demonstrated in the trap,
even at the compromised vacuum conditions imposed by the experimental set up.
The significance for future ultra-low energy experiments, including portable
antiproton traps, is discussed.Comment: 12 pages, latex; 4 figures, uufiled. Slightly expanded discussion of
expected energy dependence of annihilation cross section and rate, and of
estimates of trap pressure, plus minor text improvement
A new model for QPOs in accreting black holes: application to the microquasar GRS 1915+105
(abridged) In this paper we extend the idea suggested previously by Petri
(2005a,b) that the high frequency quasi-periodic oscillations observed in
low-mass X-ray binaries may be explained as a resonant oscillation of the
accretion disk with a rotating asymmetric background (gravitational or
magnetic) field imposed by the compact object. Here, we apply this general idea
to black hole binaries. It is assumed that a test particle experiences a
similar parametric resonance mechanism such as the one described in paper I and
II but now the resonance is induced by the interaction between a spiral density
wave in the accretion disk, excited close to the innermost stable circular
orbit, and vertical epicyclic oscillations. We use the Kerr spacetime geometry
to deduce the characteristic frequencies of this test particle. The response of
the test particle is maximal when the frequency ratio of the two strongest
resonances is equal to 3:2 as observed in black hole candidates. Finally,
applying our model to the microquasar GRS 1915+105, we reproduce the correct
value of several HF-QPOs. Indeed the presence of the 168/113/56/42/28 Hz
features in the power spectrum time analysis is predicted. Moreover, based only
on the two HF-QPO frequencies, our model is able to constrain the mass and angular momentum of the accreting black hole.Comment: Accepted for publication in Astrophysics & Space Scienc
Myers' type theorems and some related oscillation results
In this paper we study the behavior of solutions of a second order
differential equation. The existence of a zero and its localization allow us to
get some compactness results. In particular we obtain a Myers' type theorem
even in the presence of an amount of negative curvature. The technique we use
also applies to the study of spectral properties of Schroedinger operators on
complete manifolds.Comment: 16 page
Enhanced Spin Dependent Shot Noise in Magnetic Tunnel Barriers
We report the observation of enhanced spin dependent shot noise in magnetic
tunnel barriers, suggesting transport through localized states within the
barrier. This is supported by the existence of negative magnetoresistance and
structure in the differential conductance curves. A simple model of tunneling
through two interacting localized states with spin dependent tunneling rates is
used to explain our observations.Comment: 8 pages, 8 figures, submitted to Physica E (proceedings of the
seminar on Quantum Coherence, Noise and Decoherence in Nanostructures
Focus groups as a qualitative method for crosscultural research in social gerontology
The focus group approach for collecting qualitative data can be usefully applied in social gerontological studies, both in a single setting and cross-culturally. The experiences of the research terms participating in the Comparative Study of Asian Elderly in employing focus groups are described, and their advantages and disadvantages as a general method for gathering basic qualitative data are discussed. While the method has promise, it also should be recognized that conducting focus group research within the context of a comparative study compounds the considerable time, effort, and funds that focus group research for basic social science already requires.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/42971/1/10823_2004_Article_BF00972029.pd
Fast variability from black-hole binaries
Currently available information on fast variability of the X-ray emission
from accreting collapsed objects constitutes a complex phenomenology which is
difficult to interpret. We review the current observational standpoint for
black-hole binaries and survey models that have been proposed to interpret it.
Despite the complex structure of the accretion flow, key observational
diagnostics have been identified which can provide direct access to the
dynamics of matter motions in the close vicinity of black holes and thus to the
some of fundamental properties of curved spacetimes, where strong-field general
relativistic effects can be observed.Comment: 20 pages, 11 figures. Accepted for publication in Space Science
Reviews. Also to appear in hard cover in the Space Sciences Series of ISSI
"The Physics of Accretion onto Black Holes" (Springer Publisher
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