Satisfacción en el trabajo y capacidad para el trabajo entre docentes universitarios

O objetivo principal deste estudo foi verificar a correlação entre satisfação no trabalho e capacidade para o trabalho de docentes universitários. Este é um estudo transversal de abordagem quantitativa. Dele fizeram parte 154 docentes, dos quais 50,6% eram homens e 49,4% eram mulheres e cuja idade média era de 39,25 anos. A coleta de dados incluiu três questionários: 1. Dados sociodemográficos e funcionais, 2. Escala de satisfação no trabalho; 3. Índice de capacidade para o Trabalho - ICT. A satisfação no trabalho e o ICT mostraram correlação estatisticamente significativa (r=0,23, p<0,01). Conclui-se que o aumento da satisfação no trabalho pode melhorar a capacidade para o trabalho entre os docentes.The main aim of this study was to verify the correlation between job satisfaction and work ability among college educators. A quantitative approach was carried out in a cross-sectional design. The study included 154 educators, among them 50.6% were male and 40.4% female, with mean age of 39.25 years. Data collection included three questionnaires: 1. Socio-demographic and functional data; 2. Job satisfaction scale; 3. Work Ability Index -WAI. Job satisfaction and WAI showed a significant statistically correlation (r=0.23, p<0.01). It can be conclude that the increase of job satisfaction can improve the educator’s work ability.El principal objetivo del presente estudio fue comprobar si hay correlación entre satisfacción en el trabajo y la capacidad para el trabajo de docentes universitarios. Se refiere a un estudio transversal de abordaje cuantitativo. Tomaron parte del estudio 154 docentes. La compilación de datos envolvió tres cuestionarios: 1. Datos socio-demográficos y funcionales, 2. Escala de satisfacción en el trabajo; 3. Índice de Capacidad para el Trabajo - ICT. La satisfacción en el trabajo y el ICT revelaron correlación estadística significante (r=0,23, p<0,01). Se concluye que la satisfacción en el trabajo puede aumentar la capacidad para el trabajo entre los docentes

Fortalecimiento de los procesos de atención a través de elementos lúdicos

Este documento presenta un ejercicio de reconocimiento, de una de las dificultades que se encuentra presente en la mayoría de los espacios educativos donde desempeñamos nuestra labor como docente, la situación abordada, hace referencia al fortalecimiento de los procesos de atención y concentración de los estudiantes, especialmente aquellos casos que requieren de un acompañamiento especial. Para esta propuesta, se partió de un ejercicio de observación acerca de las relaciones que se presentan en los espacios académicos y de formación de los estudiantes de grado 3-E. Luego a partir de la recolección de datos de información y de un análisis que surgió a partir de la aplicación de una encuesta, se diseñó una propuesta denominada: Para conocer y aprender juntos… en esta se plantea y se desarrollan cuatro momentos que buscan acompañar los procesos de atención y concentración de los estudiantes a partir de la implementación de elementos lúdicos y didácticos, con el fin de colaborar en la superación de las dificultades presentadas. Este ejercicio de intervención pedagógica, sirve como espacio de reflexión frente al quehacer pedagógico, toda vez que nos permite revisar nuestras prácticas en pro del mejoramiento de los ambientes de aprendizaje

Effects of irregular-shift work and physical activity on cardiovascular risk factors in truck drivers

OBJETIVO: Analisar o efeito presumido do turno de trabalho e sua interação com a atividade física no tempo de lazer nos fatores de risco cardiovasculares em motoristas de caminhão. MÉTODOS: Um estudo transversal foi conduzido com 57 motoristas de caminhão do sexo masculino que trabalhavam em uma transportadora de cargas, dos quais 31 trabalhavam no turno irregular e 26 no turno diurno. Os participantes registraram sua atividade física por meio do questionário Internacional de atividade física; foi aferida a pressão arterial, calculado o índice de massa corporal e a relação cintura-quadril; e também forneceram uma amostra de sangue dos motoristas de caminhão, em jejum, para análise dos fatores lipídicos. Os dados foram avaliados utilizando modelo fatorial controlado pelas covariáveis: idade, tabagismo, demanda de trabalho, controle no trabalho e apoio social. RESULTADOS: A maioria dos motoristas do turno irregular e do turno diurno trabalhava mais de oito horas por dia (67,7% e 73,1%, respectivamente). O tempo de experiência no trabalho no horário irregular foi de 15,7 anos. Trabalhadores diurnos nunca trabalharam no turno irregular e trabalhavam como motoristas de caminhão em média havia 10,8 anos. Os motoristas do turno irregular apresentaram menor demanda e controle no trabalho comparados aos motoristas do turno diurno (p < 0,05). Os motoristas do turno irregular, moderadamente ativos, apresentaram maiores pressões arteriais sistólica e diastólica (143,7 mmHg e 93,2 mmHg, respectivamente) do que os motoristas diurnos, moderadamente ativos (116 mmHg e 73,3 mmHg, respectivamente) (p < 0,05), assim como maior concentração de colesterol total que os motoristas diurnos moderadamente ativos (232,1 mg/dl e 145 mg/dl, respectivamente) (p = 0,01). Independentemente da prática de atividade física, motoristas irregulares apresentaram concentrações mais elevadas de colesterol total e LDL-colesterol (211,8 mg/dl e 135,7 mg/dl, respectivamente) do que os diurnos (161,9 mg/dl e 96,7 mg/dl, respectivamente) (ANCOVA, p < 0,05). CONCLUSÕES: Motoristas de caminhão são expostos a fatores de risco cardiovasculares devido às características próprias de seu trabalho, com grande demanda, extensa jornada e tempo de trabalho na profissão, independentemente do turno de trabalho e da atividade física no tempo de lazer.OBJETIVO: Analizar el efecto presumido del turno de trabajo y su interacción con la actividad física en el tiempo libre en los factores de riesgo cardiovasculares en conductores de camión. MÉTODOS: Estudio transversal conducido con 57 conductores de camión del sexo masculino que trabajaban en una transportadora de cargas, 31 de ellos en turno irregular y 26 en turno diurno. Los participantes registraron actividad física a través del Cuestionario Internacional de Actividad Física, se les midió la presión arterial, se calculó el índice de masa corporal y la relación cintura-cadera. Asimismo, los participantes suministraron una muestra de sangre, en ayunas, para análisis de factores lipídicos. Los datos fueron analizados utilizando el modelo factorial controlado por las co-variables: edad, tabaquismo, demanda de trabajo, control en el trabajo y apoyo social. RESULTADOS: La mayoría de los conductores, tanto del turno irregular como del turno diurno, trabajaba más de ocho horas por día (67,7% y 73,1%, respectivamente). El tiempo de experiencia en el trabajo en el horario irregular fue de 15,7 años. Los trabajadores diurnos nunca trabajaron en el turno irregular y trabajaban, en promedio, como conductores de camión hace 10,8 años. Los conductores del turno irregular presentaron menor demanda y control en el trabajo en comparación con los conductores del turno diurno (p˂ 0,05). Los conductores del turno irregular, moderadamente activos, presentaron mayores presiones arteriales sistólica y diastólica (143m7 y 93,2 mmHg, respectivamente) que los conductores diurnos, moderadamente activos (116 y 73,3 mmHg, respectivamente) (p˂ 0,05), así como mayor concentración de colesterol total en comparación con los conductores diurnos moderadamente activos (116 y 73,3 mmHg, respectivamente) (p=0,01). Independientemente de la práctica de actividad física, los conductores irregulares presentaron concentraciones más elevadas de colesterol total y LDL-colesterol (211,8 y 135,7 mg/dl, respectivamente) que los del turno diurno (161,9 y 96,7 mg/dl, respectivamente) (ANCOVA, p˂0,05). CONCLUSIONES: Los conductores de camión están expuestos a factores de riesgo cardiovasculares debido a las características propias de su trabajo, con gran demanda, extensa jornada y tiempo de trabajo en la profesión, independientemente del turno de trabajo y de la actividad física en el tiempo libre.OBJECTIVE: To analyze the putative effect of type of shift and its interaction with leisure-time physical activity on cardiovascular risk factors in truck drivers. METHODS: A cross-sectional study was undertaken on 57 male truck drivers working at a transportation company, of whom 31 worked irregular shifts and 26 worked on the day-shift. Participants recorded their physical activity using the International Physical Activity Questionnaire along with measurements of blood pressure, body mass index and waist-hip ratio. Participants also provided a fasting blood sample for analysis of lipid-related outcomes. Data were analyzed using a factorial model which was covariate-controlled for age, smoking, work demand, control at work and social support. RESULTS: Most of the irregular-shift and day-shift workers worked more than 8 hours per day (67.7% and 73.1%, respectively). The mean duration of experience working the irregular schedule was 15.7 years. Day-shift workers had never engaged in irregular-shift work and had been working as a truck driver for 10.8 years on average. The irregular-shift drivers had lower work demand but less control compared to day-shift drivers (p < 0.05). Moderately-active irregular-shift workers had higher systolic and diastolic arterial pressures (143.7 and 93.2 mmHg, respectively) than moderately-active day-shift workers (116 and 73.3 mmHg, respectively) (p < 0.05) as well as higher total cholesterol concentrations (232.1 and 145 mg/dl, respectively) (p = 0.01). Irrespective of their physical activity, irregular-shift drivers had higher total cholesterol and LDL-cholesterol concentrations (211.8 and 135.7 mg/dl, respectively) than day-shift workers (161.9 and 96.7 mg/dl, respectively (ANCOVA, p < 0.05). CONCLUSIONS: Truck drivers are exposed to cardiovascular risk factors due to the characteristics of the job, such as high work demand, long working hours and time in this profession, regardless of shift type or leisure-time physical activity

Produtivismo acadêmico: quando a demanda supera o tempo de trabalho

OBJECTIVE: To assess the association between the perception of pressure to publish academic work with job satisfaction and stress. METHODS: Cross-sectional study with 64 graduate advisors from a public university in the city of São Paulo. Data collection conducted via an online questionnaire that included: sociodemographic, work and health data; Occupational Stress Indicator Job Satisfaction Scale and Effort-Reward Imbalance (ERI) model. To assess the perception of pressure to publish academic work the advisors answered a numerical scale, assigning a score from 0 to 10 to how pressured they felt to publish their work (being 0 no pressure and 10 high pressure). Later, the generalized linear model was used to test the factors associated to high perception of pressure to publish academic work, adjusted for working time, academic management role and productivity grant. RESULTS: Advisors who had already worked in a higher education institution, who performed part of the work at home and who reported work stress were more likely to show perception of extreme pressure to publish academic work. This perception was associated with greater effort and over-commitment, as well as a greater imbalance between the effort employed and the reward received at work. CONCLUSIONS: The findings suggest that the professors’ work organization and mental health are interrelated: the higher the perception of pressure to publish academic work, the greater the stress. However, this result does not seem to be reflected in the job satisfaction (or dissatisfaction). The apparently deliberate extension of working hours hides the precariousness and increased work to which professors have been subjected in recent years by public policies that commercialize education in Brazil.OBJETIVOS: Avaliar a associação entre a percepção da pressão por publicações com a satisfação e o estresse no trabalho. MÉTODOS: Estudo transversal com 64 orientadores de pós-graduação de uma universidade pública da cidade de São Paulo. A coleta de dados ocorreu por meio de um questionário on-line que incluiu: dados sociodemográficos, laborais e de saúde; Escala de Satisfação no Trabalho do Occupational Stress Indicator e modelo Desequilíbrio Esforço-Recompensa (DER). Para avaliar a percepção da pressão por publicação foi criada uma escala numérica na qual o orientador deveria atribuir uma nota de 0 a 10 para o quanto se sentia pressionado a publicar seus trabalhos (sendo 0 nenhuma pressão e 10 muita pressão). Posteriormente, foi utilizado o modelo linear generalizado para testar os fatores associados à alta percepção de pressão para publicação, ajustado pelo tempo de trabalho, função de gestão acadêmica e bolsa produtividade. RESULTADOS: Maiores proporções da percepção de elevada pressão para publicação foram encontradas entre orientadores que já haviam trabalhado em instituição de ensino superior, que realizavam parte do trabalho em casa e que apresentavam estresse laboral. Associou-se essa percepção a um maior esforço e comprometimento excessivo no trabalho, bem como a um maior desequilíbrio entre o esforço empregado e a recompensa recebida no trabalho. CONCLUSÕES: Os achados desta pesquisa sugerem que a organização do trabalho e a saúde mental dos trabalhadores estejam inter-relacionados: quanto maior a percepção de pressão por publicação maior o estresse. No entanto, esse resultado parece não se refletir na satisfação (ou insatisfação) do trabalho. O prolongamento aparentemente deliberado das horas de trabalho oculta a precarização e intensificação do trabalho a que os professores têm sido submetidos nos últimos anos pelas políticas públicas que mercantilizam a educação no Brasil

One-pot synthesis of green-emitting nitrogen-doped carbon dots from xylose

Carbon dots (CDs) are interesting carbon nanomaterials that exhibit great photoluminescent features, low cytotoxicity, and excellent water stability and solubility. For these reasons, many fields are starting to integrate their use for a variety of purposes. The catalytic performance of VOPO4 has been evaluated in the synthesis of nitrogen-doped carbon dots (N-CDs). The synthesis reaction was carried out at 180 °C using VOPO4 as a heterogeneous catalyst for 2 to 4 h of reaction time. After reaction, the N-CDs were purified using a novel method for the protection of the functional groups over the surfaces of the N-CDs. The morphological, superficial, and photoelectronic properties of the N-CDs were thoroughly studied by means of TEM, HRTEM, XPS, and photoluminescence measurements. The conversion of the carbon precursor was followed by HPLC. After three catalytic runs, the catalyst was still active while ensuring the quality of the N-CDs obtained. After the third cycle, the catalyst was regenerated, and it recovered its full activity. The obtained N-CDs showed a great degree of oxidized groups in their surfaces that translated into high photoluminescence when irradiated under different lasers. Due to the observed photoelectronic properties, they were then assayed in the photocatalytic degradation of methyl orange.This research was funded by the Spanish Ministry of Science and Innovation (PID2021-122736OB-C42, PID2021-122613OB-I00) and FEDER (European Union) funds (PID2021-122736OB-C42, P20-00375, UMA20-FEDERJA88)

Estrategia de gestión educativa basada en el acompañamiento socio afectivo escolar de los estudiantes del ciclo uno a través de la escuela de familia

El objetivo de esta investigación es el diseño y aplicación de una estrategia de gestión, basada en el acompañamiento socio afectivo escolar de los estudiantes del ciclo uno a través de la participación de los padres o familiares en la Escuela de Familia de la institución Educativa Villas del Progreso de la localidad de Bosa en Bogotá. Esta propuesta de escuela de familia tiene como novedad, el papel del docente como orientador pedagógico de procesos socio afectivos escolares de las familias de los estudiantes del ciclo uno

Innovative Therapeutic and Delivery Approaches Using Nanotechnology to Correct Splicing Defects Underlying Disease

Alternative splicing of pre-mRNA contributes strongly to the diversity of cell- and tissue-specific protein expression patterns. Global transcriptome analyses have suggested that >90% of human multiexon genes are alternatively spliced. Alterations in the splicing process cause missplicing events that lead to genetic diseases and pathologies, including various neurological disorders, cancers, and muscular dystrophies. In recent decades, research has helped to elucidate the mechanisms regulating alternative splicing and, in some cases, to reveal how dysregulation of these mechanisms leads to disease. The resulting knowledge has enabled the design of novel therapeutic strategies for correction of splicing-derived pathologies. In this review, we focus primarily on therapeutic approaches targeting splicing, and we highlight nanotechnology-based gene delivery applications that address the challenges and barriers facing nucleic acid-based therapeutics.Fil: Suñé Pou, Marc. Universidad de Barcelona; EspañaFil: Limeres, María José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; ArgentinaFil: Moreno Castro, Cristina. Institute of Parasitology and Biomedicine “López-Neyra"; EspañaFil: Hernández Munain, Cristina. Institute of Parasitology and Biomedicine “López-Neyra"; EspañaFil: Suñé Negre, Josep M.. Universidad de Barcelona; EspañaFil: Cuestas, María Luján. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; ArgentinaFil: Suñé, Carlos. Institute of Parasitology and Biomedicine “López-Neyra"; Españ

Development and characterization of an improved formulation of cholesteryl oleate-loaded cationic solid-lipid nanoparticles as an efficient non-viral gene delivery system

Nanoparticle-mediated plasmid delivery is considered a useful tool to introduce foreign DNA into the cells for the purpose of DNA vaccination and/or gene therapy. Cationic solid-lipid nanoparticles (cSLNs) are considered one of the most promising non-viral vectors for nucleic acid delivery. Based on the idea that the optimization of the components is required to improve transfection efficiency, the present study aimed to formulate and characterize cholesteryl oleate-containing solid-lipid nanoparticles (CO-SLNs) incorporating protamine (P) to condense DNA to produce P:DNA:CO-SLN complexes as non-viral vectors for gene delivery with reduced cytotoxicity and high cellular uptake efficiency. For this purpose, CO-SLNs were used to prepare DNA complexes with and without protamine as DNA condenser and nuclear transfer enhancer. The main physicochemical characteristics, binding capabilities, cytotoxicity and cellular uptake of these novel CO-SLNs were analyzed. Positively charged spherical P:DNA:CO-SLN complexes with a particle size ranging from 330.1 ± 14.8 nm to 347.0 ± 18.5 nm were obtained. Positive results were obtained in the DNase I protection assay with a protective effect of the genetic material and 100% loading efficiency was achieved at a P:DNA:CO-SLN ratio of 2:1:7. Transfection studies in human embryonic kidney (HEK293T) cells showed the versatility of adding protamine to efficiently transfect cells, widening the potential applications of CO-SLN-based vectors, since the incorporation of protamine induced almost a 200-fold increase in the transfection capacity of CO-SLNs without toxicity. These results indicate that CO-SLNs with protamine are a safe and effective platform for non-viral nucleic acid delivery.Fil: Limeres, María José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad de Barcelona; EspañaFil: Suñé Pou, Marc. Consejo Superior de Investigaciones Científicas; España. Universidad de Barcelona; EspañaFil: Prieto Sanchez, Silvia. Consejo Superior de Investigaciones Científicas; EspañaFil: Moreno Castro, Cristina. Consejo Superior de Investigaciones Científicas; EspañaFil: Nusblat, Alejandro David. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Nanobiotecnología. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Nanobiotecnología; ArgentinaFil: Hernandez Munain, Cristina. Consejo Superior de Investigaciones Científicas; EspañaFil: Castro, Guillermo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; ArgentinaFil: Suñe, Carlos. Consejo Superior de Investigaciones Científicas; EspañaFil: Suñé nNegre, Josep M.. Universidad de Barcelona; EspañaFil: Cuestas, María Luján. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentin

Clonal effect on rooting and acclimation rates for in-vitro micropropagation in hybrid walnut (Juglans x intermedia Mj 209): preliminary observations

The success of walnut (Juglans sp.) planted forests for timber production have been very variable and genetic material is considered as one of the main drivers (together with site selection and forest management) for the success or failure of the plantations, as the performance of the trees from seed material is very variable. Considering the relevance of this genetic material, several clones have been selected and research have been conducted in order to improve micropropagation procedures. The objective of the present study is to analyze the effects of different clones in the rooting and acclimation rates for in-vitro micropropagation in hybrid walnut (Juglans x intermedia Mj 209). The results show a significative effect of clones on the rooting and the total micropropagation efficiency rates, but not on the acclimation rate. The efficiency rate of D-117 (65%) is considered statistically higher than the one for D-15 (38%), caused by a higher rooting rate of D-117 (73%) compared with D-15 (55%), because acclimation rate (57%) did not show any clone effect. Considering these differences in the micropropagation success, it might be considered (together with other factors) for clone selection to increase the general performance of the plant production units in large-scale propagation

Innovative Therapeutic and Delivery Approaches Using Nanotechnology to Correct Splicing Defects Underlying Disease

Alternative splicing of pre-mRNA contributes strongly to the diversity of cell- and tissue-specific protein expression patterns. Global transcriptome analyses have suggested that >90% of human multiexon genes are alternatively spliced. Alterations in the splicing process cause missplicing events that lead to genetic diseases and pathologies, including various neurological disorders, cancers, and muscular dystrophies. In recent decades, research has helped to elucidate the mechanisms regulating alternative splicing and, in some cases, to reveal how dysregulation of these mechanisms leads to disease. The resulting knowledge has enabled the design of novel therapeutic strategies for correction of splicing-derived pathologies. In this review, we focus primarily on therapeutic approaches targeting splicing, and we highlight nanotechnology-based gene delivery applications that address the challenges and barriers facing nucleic acid-based therapeutics