La Escuela Moderna. Una iniciativa pedagógica con vocación de futuro

Máster Universitario en Formación del Profesorado de ESO, Bachillerato, Formación Profesional y Enseñanza de Idiomas. Especialidad en Física y Química (M106

Archivos universitarios e historia de las universidades

[Actas de:] Jornadas "Archivos universitarios e historia de las universidades", 23 y 24 de mayor de 2002: Universidad Carlos III de Madrid (España)Esta obra es resultado de las jornadas sobre Archivos e Historia de las Universidades organizadas en 2002 por el Instituto Antonio de Nebrija de la Universidad Carlos III de Madrid, en la que se dieron cita representantes de los distintos colectivos profesionales que centran sus actividades en el ámbito de los archivos universitarios y de las historia de las universidades. Se trata de dos grupos profesionales: archiveros e investigadores, reunidos por primera vez para establecer las líneas respectivas de acción y el ámbito científico de confluencia. En el texto se trata con carácter novedoso el estado de la gestión de los documentos, en especial de las universidades de reciente factura, lo que constituye la base para lo que en la actualidad y en el futuro serán las fuentes para el estudio de las universidades contemporáneas. También se analizan las últimas tendencias en la materia y de manera señalada cabe reseñar la presentación de los proyectos llevados a cabo por la Conferencia de Archiveros de Universidades orientados al servicio de los investigadores, y el análisis sobre el derecho de acceso y las implicaciones legales que comporta el uso de documentos contemporáneos. Todo ello, caracterizado por la relevancia científica, el relieve internacional y la acreditada experiencia profesional de los ponentes, que ofrecen lo mejor de su conocimiento y que, en buena medida, queda reflejado en estas páginas.Presentación / José Ramón Cruz Mundet. -- Los fondos universitarios para la historia de las universidades / Ascensión Lluch Adelantado. -- La gestión de los documentos en las universidades. ¿Una solución perdurable? / Antoni Borfo Bach. -- La conferencia de archiveros de las universidades españolas / Ángeles Montes Zugadi. -- Los archivos universitarios y la historia de las universidades: perspectiva de los investigadores / Elena Hernández Sandoica. -- El Archivo General de la Universidad Complutense: punto de inflexión / Carlos Flores Varela. -- Panorama de los archivos universitarios en la red. El mapa web de archivos de las universidades españolas / Pilar Gil García. -- Los archivos históricos de las universidades más antiguas de Bogotá / María Clara Guillén de Iriarte. -- Des memoires audovisuelles. L’experience des archives de l’Université Catholique de Louvain / Françoise Hiraux. -- Los estudios de doctorado y el inicio de las tesis doctorales en España. 1847-1900 / Aurora Miguel Alonso. -- Graduados universitarios de Castellón en la Universidad de Valencia en el siglo XVIII / María Lidón París Folch. -- La importancia de un patrimonio documental: los archivos científicos / Carmen María Pérez-Montes Salmerón y Mar Caso Neira. -- O sistema de informação arquivística da universidade do Porto: potenciar o uso da memória informacional retroprospectivamente / Fernanda Ribeiro y María Eugénia Matos Fernandes. -- La política archivística de la Universidad de Alcalá durante los siglos XVI al XIX. Una aproximación a su estudio / María Elena Sotelo Martín y Rogelio Pacheco Sampedro. -- Los inventarios de documentación del archivo histórico universitario de Zaragoza (1603-1983) / Guillermo Vicente y Guerrero

Heritage and the Sea: Maritime History and Archaeology of the Global Iberian World (15th -18th centuries)

This two-volume set highlights the importance of Iberian shipbuilding in the centuries of the so-called first globalization (15th to 18th), in confluence with an unprecedented extension of ocean navigation and seafaring and a greater demand for natural resources (especially timber), mostly oak (Quercus spp.) and Pine (Pinus spp.). The chapters are framed in a multidisciplinary and interdisciplinary line of research that integrates history, Geographic Information Sciences, underwater archaeology, dendrochronology and wood provenance techniques. This line of research was developed during the ForSEAdiscovery project, which had a great impact in the academic and scientific world and brought together experts from Europe and America. The volumes deliver a state-of-the-art review of the latest lines of research related to Iberian maritime history and archaeology and their developing interdisciplinary interaction with dendroarchaeology. This synthesis combines an analysis of historical sources, the systematic study of wreck-remains and material culture related to Iberian seafaring from the 15th to the 18th centuries, and the application of earth sciences, including dendrochronology. The set can be used as a manual or work guide for experts and students, and will also be an interesting read for non-experts interested in the subject.Volume 1 focuses on the history and archaeology of seafaring and shipbuilding in the Iberian early modern world, complemented by case studies on timber trade and supply for shipbuilding, analysis of shipbuilding treatises, and the application of Geographic Information Systems and Databases (GIS) to the study of shipwrecks.Volume 2 focuses on approaches to the study of shipwrecks including a synthesis of dendro-archaeological results, current interdisciplinary case studies and the specialist study of artillery and anchors.Peer reviewe

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020

[EN] Following its emergence in late 2019, the spread of SARS-CoV-21,2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail3,4,5. Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes.S

RICORS2040 : The need for collaborative research in chronic kidney disease

Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true

Structure, dynamics and conductivities of ionic liquid-alcohol mixtures

We study the microscopic structure and transport properties of ions in mixtures of 1-butyl-3-methylimidazolium and 1-butyl-3-ethylimidazolium iodide with ethanol using atomistic molecular dynamics simulations and conductivity measurements. Compared with the same ionic liquids in water, we reveal essential differences in ionic structure that are closely related to the differences in the solubility mechanisms of both types of solvents. In particular, unlike for aqueous solutions, we find a homogeneous distribution of solvent molecules in the system, i.e., we observe no cluster formation, which agrees with the nano-structured solvation paradigm. In addition, we calculate the conductivities of these systems in the whole concentration range and compare them with experimental data. Although the simulated values slightly underestimate the experimental ones, they reproduce the shape of the experimental conductivity dome reasonably well. We also show that the pseudo-lattice random-alloy model, which is based on microscopic ion jumping frequencies, describes the conductivity data accurately. We compute the average jumping frequencies directly from simulations and find that they agree well with those obtained by fitting the simulation conductivity data. These results show that the pseudo-lattice random-alloy model provides a valuable tool to describe the conductivities of ionic liquid–solvent mixtures and particularly their concentration dependence. It shall also apply to other systems, e.g., inorganic electrolytes and dispersed ionic conductorsThe financial support of the Spanish Ministry of Economy and Competitiveness (Projects MAT2017-89239-C2-1-P and MAT2017-89239- C2-2-P) is gratefully acknowledged. Moreover, this work was funded by the Xunta de Galicia (ED431D 2017/06, ED431E 2018/08, GRC ED431C 2016/001 and GRC ED431C 2020/10)S

Teosinte (Dioon mejiae) Flour: Nutritional and Physicochemical Characterization of the Seed Flour of the Living Fossil in Honduras

Teosinte (Dioon mejiae) is a dioecious tree native to Honduras, whose seeds are used to make flour for the preparation of traditional foods and beverages. The objective was to evaluate the nutritional and physicochemical composition of teosinte flour for the first time. Using diverse techniques, teosinte flour was found to be a high-calorie food rich in total carbohydrates and mainly composed of starch, with an amylopectin:amylose ratio of 2:1 and a concentration of resistant starch greater than 50%. Its proteins were similar to other cereals in which the essential amino acids glutamic acid, leucine, and especially lysine were the most important. Some 75% of its total dietary fiber was insoluble. The fatty acid profile was characterized by a high unsaturated fatty acid content in which oleic acid (C18:1) and linoleic acid (C18:2) predominated. As for minerals, teosinte flour had higher iron content, lower sodium concentration, and similar zinc, calcium, and phosphorus content to other cereal flours. We highlight that teosinte flour has nutrients and qualities that convert it into flour with excellent nutritional abilities and health benefits; it is also a very good industrial and technological alternative to be mixed mainly with types of flour from other sources

In vitro study of the protective effect of manganese against vanadium mediated nuclear and mitochondrial DNA damage

We aimed to study the effect of vanadium(V) exposure on cell viability, nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) and to elucidate if these effects can be reverted by co-exposure to V and manganese (Mn). HepG2 cells were incubated with various concentrations of bis(maltolato)oxovanadium(IV) or MnC12 for 32 h for viability study. The higher concentrations (59 mu M V, 54 nM Mn and 59 mu M V+54 nM Mn) were used to study DNA damage and uptake of V and Mn. Comet assay was used for the study of nDNA damage; mtDNA damage was studied by determining deletions and number of copies of the ND1/ND4 mtDNA region. Cellular content of V and Mn was determined using ICPMS. Cellular exposure to 59 mu M V decreased viability (14%) and damaged nDNA and mtDNA. This effect was partially prevented by the co-exposure to V + Mn. Exposure to V increased the cellular content of V and Mn (812.3% and 153.5%, respectively). Exposure to Mn decreased the content of V and Mn (62% and 56%, respectively). Exposure to V + Mn increased V (261%) and decreased Mn (56%) content. The positive effects on cell viability and DNA damage when incubated with V + Mn could be due to the Mn-mediated inhibition of V uptake.Consejeria de Innovacion, Ciencia y Empresa, Andalusian Regional Government P06-CTS-0143