Molluscum contagiosum on tattoo

Molusco contagioso é uma dermatovirose causada por poxvírus e caracterizada por erupção benigna e autolimitada de uma ou múltiplas pápulas esféricas e brilhantes. A transmissão habitualmente ocorre por contato direto com indivíduos infectados. Relata-se caso de doente masculino, 22 anos, com história de surgimento de numerosas pápulas umbilicadas localizadas estritamente sobre a região de uma tatuagem. Exame histopatológico de uma das pápulas confirmou a hipótese clínica de molusco contagioso. Os autores descrevem uma manifestação pouco frequente da disseminação desse vírus em tatuagens e apresentam uma revisão da literatura, enfatizando as vias de transmissão e a terapêutica do molusco contagioso.Molluscum contagiosum is a disease caused by a poxvirus characterized by benign self-limited eruption of single or multiple cutaneous spherical and pearly papules. Transmission usually occurs by direct contact with infected hosts. It is reported the case of a 22-year-old Caucasian male who presented characteristic pearly and umbilicated papules strictly located on the region of a tattoo. Histopathologic exam confirmed the diagnosis of molluscum contagiosum. The authors describe an uncommomn manifestation of dissemination of this virus in tattoos and also present a literature review emphasizing the transmission pathways and treatment of Molluscum contagiosum

Multi-stage Biomarker Models for Progression Estimation in Alzheimer’s Disease

The estimation of disease progression in Alzheimer’s disease (AD) based on a vector of quantitative biomarkers is of high interest to clinicians, patients, and biomedical researchers alike. In this work, quantile regression is employed to learn statistical models describing the evolution of such biomarkers. Two separate models are constructed using (1) subjects that progress from a cognitively normal (CN) stage to mild cognitive impairment (MCI) and (2) subjects that progress from MCI to AD during the observation window of a longitudinal study. These models are then automatically combined to develop a multi-stage disease progression model for the whole disease course. A probabilistic approach is derived to estimate the current disease progress (DP) and the disease progression rate (DPR) of a given individual by fitting any acquired biomarkers to these models. A particular strength of this method is that it is applicable even if individual biomarker measurements are missing for the subject. Employing cognitive scores and image-based biomarkers, the presented method is used to estimate DP and DPR for subjects from the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Further, the potential use of these values as features for different classification tasks is demonstrated. For example, accuracy of 64% is reached for CN vs. MCI vs. AD classification

Participación privada en proyectos de infraestructura y determinantes de los arreglos contractuales observados: El caso de Chile

El objetivo del Proyecto de Investigación es el de analizar y explicar las formas contractuales quese observan en seis proyectos de Infraestructura Pública en los cuales hay participación privada enChile. En consecuencia, la unidad de análisis para la investigación es el proyecto de inversión elegido y más específicamente, el arreglo contractual entre el gobierno y el privado.

Aspectos numéricos y gráficos de la derivada de orden superior

En este trabajo se muestran algunos resultados de nuestras indagaciones sobre los significados y representaciones asociados con la derivada de orden superior. Estos resultados se plantean en contextos numéricos y gráficos; y son el resultado del estudio de algunas propiedades matemáticas, y el análisis de fuentes primarias como la producción astronómica de Isaac Newton (Newton, 1687). El trabajo se inscribe en la línea de investigación denominada Pensamiento y Lenguaje Variacional (PyLV) (Cantoral y Farfán, 1998)

Socioepistemología de la predicción

Este escrito resume los planteamientos del Taller “Socioepistemología de la Predicción” donde nos ocupamos de presentar, a través de reflexiones teóricas y de una variedad de ejemplos didácticos, el papel que juega la predicción en la construcción de conocimiento matemático. Las actividades trataron con la noción de variación en el estudio de fenómenos de cambio continuo usando recursos tecnológicos diversos y experimentaciones típicamente escolares. Adicionalmente ubicamos estas experimentaciones como parte de la sociopistemología

Tackling rising inflation in sectoral collective wage bargaining

After a long period of price stability, inflation has made a remarkable comeback in the EU. In the aftermath of the COVID-19 pandemic, the energy crisis spurred by Russia's war of aggression against Ukraine and the disruption of the international supply chain, among other factors, have driven up the prices of commodities and goods. While nominal wages picked up in 2021 and 2022, real wage growth has remained below inflation, affecting mainly low-income groups. Even though EU institutions expect inflation to slowly decline by 2025, many collective bargaining rounds have barely been able to keep up with the rapid increase in prices in 2022. Consequently, trade unions' demands for compensation and pay increases in collectively agreed wages put pressure on some sectors. Updating minimum wages (in line with the directive on adequate minimum wages) plays a key role in protecting the purchasing power of low wages. With wages not keeping up with inflation rates, tensions may resurface in social dialogue and collective bargaining over the coming years

Organización industrial de los servicios de salud en Chile

El sistema de salud chileno presenta características únicas. En el país existe un mandato que obliga a los trabajadores activos y pasivos a cotizar un 7% de su ingreso para adscribirse junto a sus dependientes a un sistema de seguro de salud. Esta adscripción obligatoria puede ser al sistema público, el cual se organiza a través de una modalidad solidaria tradicional de seguridad social, o bien al sistema privado, el cual ofrece seguros de salud que obedecen a una lógica de tipo individual. La elección de uno de los sistemas es voluntaria, pero las características de los seguros ofrecidos y su precio de acceso producen una segmentación del mercado de manera tal que las personas de mayores ingresos y menor riesgo se orientan hacia el sector privado de las ISAPRE (Instituciones de Salud Previsional) y aquellos de menores ingresos y mayor riesgo de salud son atendidos en el sistema público.

Effect of “Golden Pineapple Innovation” on Costa Rica's Pineapple Exports to U.S. Market: An Econometric Approach

An investigation was conducted on the effect of introducing a new variety of pineapple, known as golden pineapple (MD2) on the level of pineapple exports to the US market. Based on historical trade data from 1983 to 2017, a univariate structural econometric model was adjusted including variables related to export demand and isolating the effect of innovation through a binary control variable. The results obtained show that the effect of the innovation was a 25.27% increase in exports from Costa Rica to the North American market since the innovation was implemented. Conveniently, agricultural policymakers should consider similar studies to visualize the impact that innovation has on agricultural activities, and based on this, to plan, research, develop, and innovate programs within the agricultural sector.Universidad de Costa Rica/[822-B6-A06]/UCR/Costa RicaUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Agroalimentarias::Centro de Investigación en Economía Agrícola y Desarrollo Agroempresarial (CIEDA)UCR::Vicerrectoría de Docencia::Ciencias Agroalimentarias::Facultad de Ciencias Agroalimentarias::Escuela de Economía Agrícola y Agronegocio