Environmental regulation and development : a cross-country empirical analysis

The authors develop comparative indices of environmental policy and performance for 31 countries using a quantified analysis of reports prepared for the United Nations Conference on Environmental and Development. In cross-country regressions, they find a very strong, continuous association between their indicators and national income per capita, particularly when adjusted for purchasing power parity. Their results suggest a characteristic progression in development. Poor agrarian economies focus first on natural resource protection. With increased urbanization and industrialization, countries move from initial regulation of water pollution to air pollution control. The authors highlight the importance of institutional development. Environmental regulation is more advanced in developing countries with relatively secure property rights, effective legal and judicial systems, and efficient public administration.Public Health Promotion,Environmental Economics&Policies,Health Economics&Finance,Agricultural Research,Economic Theory&Research,Environmental Economics&Policies,Health Economics&Finance,Agricultural Research,Economic Theory&Research,Environmental Governance

EFSA Panel on Biological Hazards (BIOHAZ) Panel; Scientific Opinion on the risk posed by pathogens in food of non-animal origin. Part 1 (outbreak data analysis and risk ranking of food/pathogen combinations)

Food of non-animal origin (FoNAO) is consumed in a variety of forms, and a major component of almost all meals. These food types have the potential to be associated with large outbreaks as seen in 2011 associated with VTEC O104. A comparison of the incidence of human cases linked to consumption of FoNAO and of food of animal origin (FoAO) was carried out to provide an indication of the proportionality between these two groups of foods. It was concluded that outbreak data reported as part of EU Zoonoses Monitoring is currently the only option for EU-wide comparative estimates. Using this data from 2007 to 2011, FoNAO were associated with 10% of the outbreaks, 26% of the cases, 35% of the hospitalisations and 46% of the deaths. If the data from the 2011VTEC O104 outbreak is excluded, FoNAO was associated with 10% of the outbreaks, 18% of cases, but only 8% of the hospitalisations and 5% of the deaths. From 2008 to 2011 there was an increase in the numbers of reported outbreaks, cases, hospitalisations and deaths associated with food of non-animal origin. In order to identify and rank specific food/pathogen combinations most often linked to human cases originating from FoNAO in the EU, a model was developed using seven criteria: strength of associations between food and pathogen based on the foodborne outbreak data from EU Zoonoses Monitoring (2007-11), incidence of illness, burden of disease, dose-response relationship, consumption, prevalence of contamination and pathogen growth potential during shelf life. Shortcomings in the approach using outbreak data were discussed. The top ranking food/pathogen combination was Salmonellaspp. and leafy greens eaten raw followed by (in equal rank) Salmonellaspp. and bulb and stem vegetables, Salmonellaspp. and tomatoes, Salmonellaspp. and melons, and pathogenic Escherichia coli and fresh pods, legumes or grain

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

Automation and world competition

노트 : A report to the Korea Traders association on the Project Development Strategy in the Information Age: Understanding the New Economics of Comparative Advantag

Environmental Regulation and Development: A Cross-country Empirical Analysis

This paper develops comparative indices of environmental policy and performance for 31 countries, using a quantified analysis of reports prepared for the United Nations Conference on Environment and Development (UNCED). In cross-country regressions, we find a very strong, positive association between our indicators and the level of economic development, particularly when the latter is adjusted for purchasing power parity. Our results suggest a characteristic progression in the development process, from protection of natural resources to regulation of water pollution and, finally, air pollution control. They also highlight the importance of institutional development, with significant roles for degree of private property protection, effectiveness of the legal/judicial system and efficiency of public administration. Controlling for these variables, "Green" sector indices should be positively correlated with: (1) rural population density; and (2) agricultural and forest production share of national output. "Brown" sector indices should be positively correlated with: (1) particular focus on public health, indexed by life expectancy; (2) urban share of total population; (3) urban population density; and (4) manufacturing share of national output. Our analysis of overall regulatory performance reveals strong cross-country associations with income per capita, security of property rights, and general development of the legal and regulatory system. Surprisingly, however, we find only insignificant or perverse associations with degree of popular representation and freedom of information. For both the Green and Brown indices, performance is again strongly associated with income per capita, freedom of property and (in small samples) measures of regulatory efficiency. The two specifically rural sector variables (population density; proportion of GDP in agriculture and forestry) are only weakly associated with the Green index. The fit is much better for the Brown index: degree of urbanization, population density and manufacturing share in GDP all have the expected signs and relatively high significance. Life expectancy as a proxy for public health priority has no independent effect. In summary, our findings suggest that a detailed, quantified analysis of the UNCED reports can yield comparable and plausible indices of environmental policy performance across countries. Cross-country variations in our environmental index are explained well by variations in income per capita, degree of urbanization and industrialization, security of property rights and general administrative efficiency.