Breeding latitude predicts timing but not rate of spring migration in a widespread migratory bird in South America

Identifying the processes that determine avian migratory strategies in different environmental contexts is imperative to understanding the constraints to survival and reproduction faced by migratory birds across the planet. We compared the spring migration strategies of Fork‐tailed Flycatchers (Tyrannus s. savana) that breed at south‐temperate latitudes (i.e., austral migrants) vs. tropical latitudes (i.e., intratropical migrants) in South America. We hypothesized that austral migrant flycatchers are more time‐selected than intratropical migrants during spring migration. As such, we predicted that austral migrants, which migrate further than intratropical migrants, will migrate at a faster rate and that the rate of migration for austral migrants will be positively correlated with the onset of spring migration. We attached light‐level geolocators to Fork‐tailed Flycatchers at two tropical breeding sites in Brazil and at two south‐temperate breeding sites in Argentina and tracked their movements until the following breeding season. Of 286 geolocators that were deployed, 37 were recovered ~1 year later, of which 28 provided useable data. Rate of spring migration did not differ significantly between the two groups, and only at one site was there a significantly positive relationship between date of initiation of spring migration and arrival date. This represents the first comparison of individual migratory strategies among conspecific passerines breeding at tropical vs. temperate latitudes and suggests that austral migrant Fork‐tailed Flycatchers in South America are not more time‐selected on spring migration than intratropical migrant conspecifics. Low sample sizes could have diminished our power to detect differences (e.g., between sexes), such that further research into the mechanisms underpinning migratory strategies in this poorly understood system is necessary.Fil: Jahn, Alex. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Cereghetti, Joaquín. Universidad Nacional de La Pampa; ArgentinaFil: Cueto, Víctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Centro de Investigación Esquel de Montaña y Estepa Patagóica. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales - Sede Esquel. Centro de Investigación Esquel de Montaña y Estepa Patagónica; ArgentinaFil: Hallworth, Michael T.. Smithsonian Conservation Biology Institute; Estados UnidosFil: Levey, Douglas J.. National Science Foundation; Estados UnidosFil: Marini, Miguel Â.. Universidade do Brasília; BrasilFil: Masson, Diego. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo; ArgentinaFil: Pizo, Marco A.. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Sarasola, José Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ciencias de la Tierra y Ambientales de La Pampa. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales. Instituto de Ciencias de la Tierra y Ambientales de La Pampa; ArgentinaFil: Tuero, Diego Tomas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentin

A Qualitative Analysis of Coronary Heart Disease Patients’ Views of Dietary Adherence and of Web-Based and Mobile-Based Nutrition Tools

Purpose: Dietary adherence can be challenging for patients with coronary heart disease (CHD), as they may require multiple dietary changes. Choosing appropriate food items may be difficult or take extensive amounts of time without the aid of technology. The objective of this project was to (1) examine the dietary challenges faced by patients with CHD, (2) examine methods of coping with dietary challenges, (3) explore the feasibility of a web-based food decision support system, and (4) explore the feasibility of a mobile-based food decision support system. Methods: Food for the Heart (FFH), a website-based food decision support system, and Mobile Magic Lens (MML), a mobile-based system, were developed to aid in daily dietary choices. Three CHD patient focus groups were conducted and focused on CHD-associated dietary changes as well as the FFH and MML prototypes. A total of 20 CHD patients and 7 informal caregivers participated. Qualitative, content analysis was performed to find themes grounded in the responses. Results: Five predominant themes emerged: 1) decreasing carbohydrate intake and portion control are common dietary challenges, 2) clinician and social support makes dietary adherence easier, 3) FFH could make meal-planning and dietary adherence less complicated, 4) MML could save time and assist with healthy choices, and 5) additional features need to be added to make both tools more comprehensive. Conclusions: FFH and MML may be tools that CHD patients would value in making food choices and adhering to dietary recommendations, especially if additional features are added to assist patients with changes

An Unusual Reaction and Other Observations of Sperm Whales Near Fixed-Wing Aircraft

Reported behavioral reactions by sperm whales to aircraft are sparse, highly variable, and largely anecdotal as summarized below. Observers since the whaling era began have noted that sperm whales tend to be skittish (Whitehead 2003). When documented, sperm whale reactions to both planes and helicopters range from no reaction (Clarke 1956, Gambell 1968, Green et al. 1992) to reactions such as increased surface intervals and dramatic behavioral changes (Clarke 1956, Fritts et al. 1983, Mullin et al. 1991, Würsig et al. 1998, Richter et al. 2003, 2006). Given the lack of supporting data for either case, it is important that these types of data are collected and consolidated into a cohesive document. Therefore, the specific objectives of our paper are to report our visual observations of sperm whale reactions to straight-line aircraft fly-bys (i.e., passes), to report a unique observation of a recognized “stress behavioral reaction” exhibited by sperm whales during an overhead circling by small fixed-wing aircraft, and to provide a summary review of published related studies

A quasi-experimental study to mobilize rural low-income communities to assess and improve the ecological environment to prevent childhood obesity

Citation: Peters, P., Gold, A., Abbott, A., Contreras, D., Keim, A., Oscarson, R., . . . Mobley, A. R. (2016). A quasi-experimental study to mobilize rural low-income communities to assess and improve the ecological environment to prevent childhood obesity. Bmc Public Health, 16, 7. doi:10.1186/s12889-016-3047-4Background: The Ecological Model of Childhood Overweight focuses on characteristics that could affect a child's weight status in relation to the multiple environments surrounding that child. A community coaching approach allows community groups to identify their own strengths, priorities and identity. Little to no research currently exists related to community-based efforts inclusive of community coaching in creating environmental change to prevent childhood obesity particularly in rural communities. Methods: A quasi-experimental study will be conducted with low-income, rural communities (n = 14) in the North Central region of the United States to mobilize capacity in communities to create and sustain an environment of healthy eating and physical activity to prevent childhood obesity. Two rural communities within seven Midwestern states (IN, KS, MI, OH, ND, SD, WI) will be randomly assigned to serve as an intervention or comparison community. Coalitions will complete assessments of their communities, choose from evidence-based approaches, and implement nutrition and physical activity interventions each year to prevent childhood obesity with emphasis on policy, system or environmental changes over four years. Only intervention coalitions will receive community coaching from a trained coach. Outcomes will be assessed at baseline, annually and project end using previously validated instruments and include coalition self-assessments, parental perceptions regarding the built environment, community, neighborhood, and early childhood environments, self-reflections from coaches and project staff, ripple effect mapping with coalitions and, final interviews of key stakeholders and coaches. A mixed-methods analysis approach will be used to evaluate if Community Coaching enhances community capacity to create and sustain an environment to support healthy eating and physical activity for young children. ANOVA or corresponding non-parametric tests will be used to analyze quantitative data relating to environmental change with significance set at P < .05. Dominant emergent themes from the qualitative data will be weaved together with quantitative data to develop a theoretical model representing how communities were impacted by the project. Discussion: This project will yield data and best practices that could become a model for community development based approaches to preventing childhood obesity in rural communities

Possibility of Using a Satellite-Based Detector for Recording Cherenkov Light from Ultrahigh-Energy Extensive Air Showers Penetrating into the Ocean Water

We have estimated the reflected component of Cherenkov radiation, which arises in developing of an extensive air shower with primary energy of 10^20 eV over the ocean surface. It has been shown that, under conditions of the TUS experiment, a flash of the reflected Cherenkov photons at the end of the fluorescence track can be identified in showers with zenith angles up to 20 degrees.Comment: 5 pages, 3 figures. This preprint corrects errors which appeared in the English version of the article published in Bull. Rus. Acad. Sci. Phys., 2011, Vol. 75, No. 3, p. 381. The original russian text was published in Izv. RAN. Ser. Fiz., 2011, Vol. 75, No. 3, p. 41

e‐Maintenance Framework for Strategic Asset Management in Tertiary Institutions

Tertiary institutions require buildings such as its senate building, classrooms, laboratories, administrative rooms, hostels and other offices in order to function. Providing and maintaining these buildings require a lot of planning and capital investment. The study examined the prospects of using e‐ Maintenance platform for strategic asset management in tertiary institutions. This study noted that adequate maintenance of the building infrastructural base of tertiary institutions is crucial for sustainability in the face of dwindling funds in the education sector. In order to automate the e‐ Maintenance process for strategic maintenance of the institution’s building maintenance, a use case diagram, system block diagram, sequence diagram and activity diagram were designed and presented in this study. Three (3) main users are essential in the sequence of operation of the e‐Maintenance platform. These users represent the building occupants, the facility manager and the management personnel; for effective oversite and performance monitoring. The methodology of this research includes using the combination of HTML, CSS and the C‐Sharp programming language for the interface design and server side scripting while MySQL was the database platform used for storing and retrieving the data used for the application. In conclusion, the study developed an e‐Maintenance framework for strategic asset management in tertiary institutions. Keywords Asset management Automation Construction industr

FU Orionis resolved by infrared long baseline interferometry at a 2-AU scale

We present the first infrared interferometric observations of a young stellar object with a spatial projected resolution better than 2 AU. The observations were obtained with the Palomar Testbed Interferometer. FU Ori exhibits a visibility of V^2 =0.72 +/- 0.07 for a 103 +/- 5 m projected baseline at lambda = 2.2 microns. The data are consistent on the spatial scale probed by PTI both with a binary system scenario (maximum magnitude difference of 2.7 +/- 0.5 mag and smallest separation of 0.35 +/- 0.05 AU) and a standard luminous accretion disk model (approx. accretion rate of 6e-5 Mo/yr) where the thermal emission dominates the stellar scattering, and inconsistent with a single stellar photosphere.Comment: 13 pages, 4 figures, accepted for publication in ApJ

Актуальність впровадження систем газового обліку в сучасних умовах

Free energy calculation has long been an important goal for molecular dynamics simulation and force field development, but historically it has been challenged by limited performance, accuracy, and creation of topologies for arbitrary small molecules. This has made it difficult to systematically compare different sets of parameters to improve existing force fields, but in the past few years several authors have developed increasingly automated procedures to generate parameters for force fields such as Amber, CHARMM, and OPLS. Here, we present a new framework that enables fully automated generation of GROMACS topologies for any of these force fields and an automated setup for parallel adaptive optimization of high-throughput free energy calculation by adjusting lambda point placement on the fly. As a small example of this automated pipeline, we have calculated solvation free energies of 50 different small molecules using the GAFF, OPLS-AA, and CGenFF force fields and four different water models, and by including the often neglected polarization costs, we show that the common charge models are somewhat underpolarized.QC 20150505</p

Astabiotics: Antimicrobial Signal Transduction Activators

poster abstractThe increasing prevalence of multi-drug resistant Gram-negative bacteria is a major public health concern. All available antibiotics are inhibitors of targets essential for virulence or growth. CpxRA is a highly conserved bacterial signal transduction system that responds to extracytoplasmic membrane stress. CpxA is a sensor with kinase and phosphatase activity; upon activation, CpxA donates a phosphate group to CpxR, activating a transcriptional response. Activation of CpxRA reduces the flow of protein traffic through the cytoplasmic membrane, dramatically reducing the expression of virulence determinants. Activation of CpxRA abolishes the virulence of Salmonella Typhimurium in mice. We found that activation of CpxRA crippled the ability of Haemophilus ducreyi to cause disease in experimentally infected human volunteers. Using an Escherichia coli reporter strain, we developed a high throughput screen to detect compounds that activate CpxRA. In a pilot screen of 36,000 compounds, we identified 1 class of compounds that shifts the equilibrium of CpxA to kinase activity, activating CpxR. Based on its potency, the calculated effective dose of the lead compound (a nitroindole) was 10 mg/kg. Female mice tolerated 100 mg/kg of the nitroindole given twice a day for 3 days. A CpxRA activating mutant constructed in uropathogenic E. coli (UPEC) was severely impaired in a murine urinary tract infection model; thus, activation of CpxRA is a valid treatment strategy for UPEC. However, when female mice were challenged with UPEC and treated with 100 mg/kg of the nitroindole using the schedule above, there were no differences in the recovered CFU in the urine, bladder, and kidney of sham and compound-treated mice. Future studies will include medicinal optimization of the nitroindole and identification and optimization other leads that activate CpxRA. Although our pilot test of efficacy was negative, astabiotics have great potential as broad-spectrum, adjunctive therapies to existing antimicrobials for treatment of Gram-negative infections