A search for periodic gravitational waves from three recycled pulsars using the AURIGA detector

Aims.We report on a search for continuous gravitational wave emission from three recycled radio pulsars, performed by using the data of the resonant detector AURIGA. Given the spin rate of the selected targets - the isolated pulsar PSR J1939+2134 and the binary pulsars PSR J0024-7204J and PSR J0218+4232 - the expected frequency of the emitted gravitational waves falls in the high sensitivity range of the detector. Methods.The main topic is the method, meaning that the statistical analysis is performed by implementing a slightly modified version of the Feldman and Cousins Unified Approach. Results.By using ephemerides provided by suitable radio observations of the targets, we were able to demodulate the Doppler shifts within a coherence time of 1 day, and then incoherently sum 10 daily spectra collected from December 8th to December 17th, 2006. We have found upper limits on the gravitational wave amplitudes in the order of a few units of 10-23 at 90% Confidence Level (C.L.), which translate to limits in the ellipticity of the targeted pulsars of ε \u3c 10 -4 at 90% C.L. Conclusions. The same framework can then be applied to data coming from most sensitive experiments as VIRGO or LIGO; moreover, an application to recently discovered transients in X-ray pulsars is discussed. © 2009 ESO

A Search For Periodic Gravitational Waves From Three Recycled Pulsars Using The Auriga Detector - An Implementation Of A Modified Version Of The Unified Approach Method

We report on a search for continuous gravitational wave emission from three recycled radio pulsars, performed by using the data of the resonant detector AURIGA. Given the spin rate of the selected targets – the isolated pulsar PSR J1939+2134 and the binary pulsars PSR J0024-7204J and PSR J0218+4232 – the expected frequency of the emitted gravitational waves falls in the high sensitivity range of the detector

Use of ethyleneglycol monomethyl ether as cryoprotectant in vitrification of IVP bovine embryos.

Publicado: Proceedings of the 29th Annual Meeting of the Brazilian Embryo Technology Society (SBTE); Gramado, RS, Brazil, August 20th to 23rd, 2015, and 31st Meeting of the European Embryo Transfer Association (AETE); Ghent, Belgium, September 11th and 12th, 2015. Abstracts

Predittori di efficacia nel trattamento dell'otite esterna maligna fungina: una review sistematica

Obiettivo dello studio è stato riassumere i dati della letteratura sugli aspetti clinici e la gestione abituale dell’otite esterna maligna fungina (OEMF), ed identificare possibili fattori predittivi di esito positivo del trattamento. Gli articoli sono stati inizialmente selezionati sulla base del titolo e degli abstract. Sono poi stati recuperati ed analizzati per intero seguendo criteri predeterminati. È stata stilata una lista di riferimento degli articoli selezionati per cercare eventuali pubblicazioni mancati. Gli studi raccolti sono stati infine valutati metodologicamente. Dei 143 articoli iniziali, ne sono stati selezionati 14 focalizzati sulla gestione dell’OEMF. La maggior parte di questi ha dimostrato una correlazione tra l’efficacia del trattamento, inteso come risoluzione dei sintomi, ed alcune variabili cliniche e di gestione della patologia quali l’astensione da procedure chirurgiche invasive, l’assenza di paralisi facciale, l’Aspergillus spp come patogeno causante e l’assenza di segni radiologici alla diagnosi e nel corso del follow-up. L’efficacia del trattamento dipende dalla valutazione dello stato dei nervi cranici, dal patogeno alla base e dai segni radiologici, più precisamente: l’assenza di paralisi facciale, l’Aspergillus spp e l’imaging negativo alla diagnosi e durante il follow-up correlano con la risoluzione dei sintomi. L’evidenza che il trattamento farmacologico possa associarsi ad un miglior outcome rispetto a procedure chirurgiche invasive potrebbe semplicemente riflettere il fatto che pazienti affetti da una patologia più avanzata richiedono un approccio più aggressivo mentre le forme più lievi possono essere trattate in modo conservativo. È necessario quindi prestare attenzione nell’interpretazione dei dati a causa della necessità di ulteriori studi sull’argomento

Reciprocal influence of B cells and tumor macro and microenvironments in the ApcMin/+model of colorectal cancer

One of the most fascinating aspects of the immune system is its dynamism, meant as the ability to change and readapt according to the organism needs. Following an insult, we assist to the spontaneous organization of different immune cells which cooperate, locally and at distance, to build up an appropriate response. Throughout tumor progression, adaptations within the systemic tumor environment, or macroenvironment, result in the promotion of tumor growth, tumor invasion and metastasis to distal organs, but also to dramatic changes in the activity and composition of the immune system. In this work, we show the changes of the B-cell arm of the immune system following tumor progression in the ApcMin/+model of colorectal cancer. Tumor macroenvironment leads to an increased proportion of total and IL-10-competent B cells in draining LNs while activates a differentiation route that leads to the expansion of IgA+lymphocytes in the spleen and peritoneum. Importantly, serum IgA levels were significantly higher in ApcMin/+than Wt mice. The peculiar involvement of IgA response in the adenomatous transformation had correlates in the gut-mucosal compartment where IgA-positive elements increased from normal mucosa to areas of low grade dysplasia while decreasing upon overt carcinomatous transformation. Altogether, our findings provide a snapshot of the tumor education of B lymphocytes in the ApcMin/+model of colorectal cancer. Understanding how tumor macroenvironment affects the differentiation, function and distribution of B lymphocytes is pivotal to the generation of specific therapies, targeted to switching B cells to an anti-, rather than pro-, tumoral phenotype

Searching for quasi-periodic gravitational waves from low mass x-ray binaries with AURIGA

Astrophysical models indicate that low mass x-ray binaries (LMXBs) are very promising as sources of continuous, quasi-periodic gravitational waves at high frequencies, such as those at which resonant bar detectors are operating. In this preliminary paper we quickly derive the expected amplitude of the gravitational wave signals. We show that it is likely that there may be some objects emitting in the AURIGA band. We are producing a database of possible sources and identifying the most promising ones. Our preliminary result indicates that we can achieve a good sensitivity with an observation time of about 10 days thanks to the improved sensitivity of the upgraded AURIGA detector. We also show what will be possible to perform with the advanced resonant detectors (DUAL). Finally, we briefly outline the general features of the analysis method we intend to apply postponing to a future paper the detailed discussion