De duobus Montibus Sion et Sina: transformaciones de un tratado multiautorial

El De duobus Montibus Sion et Sina, tradicionalmente considerado apócrifo, se restituye parcialmente a San Cipriano de Cartago como homilía (cap. 2), atribuyendo el resto del tratado a autores diversos. El primero de ellos, el Autor Maniqueo (cap. 3), habría añadido glosas coherentes con su credo, que inciden en las disputas entre católicos y maniqueos propias del s. IV en África. El segundo, el Redactor Dualista (cap. 5), especialmente reconocible por sus variaciones lingüísticas, añade un largo fragmento que no le es propio, el Autor Etimologizante (cap. 4), procedente de un comentario a un léxico de nombres propios de las Sagradas Escrituras. Se estudia el uso de las Sagradas Escrituras, de la sintaxis y la oratoria, distinguiéndolos entre sí, pero cada uno de ellos supone un reto propio sui generis, ya que en cada caso conviene, mediante un estudio de orientación distinta, colocarlos en su época propia y tendencia ideológica, de manera que se superponen en el texto a modo de estratos (cap. 6). Se elaboran al fin tres reconstrucciones parciales, correspondientes a cada autor, y se finaliza con una edición que contempla la totalidad de la obra (cap. 7), distinguiendo las aportaciones de cada uno. Probablemente el conjunto habría sido producto de intervenciones sobre un mismo soporte (cap. 7.3)

Stochastic packetized model predictive control for networked control systems subjects tot time-delays and dropouts

Networked Control Systems (NCS) are systems in which serial communication networks are used to exchange system information and control signals between various physical components of the systems that may be physically distributed. Major advantages of NCS include low cost, reduced weight and power requirements, simple installation and maintenance, and high reliability. Nonetheless, closing a control loop on a shared communication network introduces additional dynamics and constraints in the control problem. In addition to being bit-rate limited [1], [2], practical communitacion channels are commonly affected by packet dropouts and time delays, mainly due to transmission errors and waiting times to access the medium; see, e.g., [3]-[5] and the many references therein

Nutraceutical Extract from Dulse (Palmaria palmata L.) Inhibits Primary Human Neutrophil Activation

Palmaria palmata L. (Palmariaceae), commonly known as "dulse", is a red alga that grows on the northern coasts of the Atlantic and Pacific oceans, and is widely used as source of fiber and protein. Dulse is reported to contain anti-inflammatory and antioxidant compounds, albeit no study has investigated these effects in primary human neutrophils. Implication strategies to diminish neutrophil activation have the potential to prevent pathological states. We evaluated the ability of a phenolic dulse extract (DULEXT) to modulate the lipopolysaccharide (LPS)-mediated activation of primary human neutrophils. Intracellular reactive oxygen species (ROS) were measured by fluorescence analysis and nitric oxide (NO) production using the Griess reaction. Inflammatory enzymes and cytokines were detected by ELISA and RT-qPCR. The results show that DULEXT diminished the neutrophil activation related to the down-regulation of TLR4 mRNA expression, deceased gene expression and the LPS-induced release of the chemoattractant mediator IL-8 and the pro-inflammatory cytokines IL-1β, IL-6 and TNF-α. ROS, NO, and myeloperoxidase (MPO) were also depressed. The data indicated that DULEXT has the potential to disrupt the activation of human primary neutrophils and the derived inflammatory and prooxidant conditions, and suggest a new role for Palmaria palmata L. in the regulation of the pathogenesis of health disorders in which neutrophils play a key role, including atherosclerosisSpanish Ministry of Science, Innovation and Universities grant CYTED-2019 119RT056

Stochastic packetized model predictive control for networked control systems subjects tot time-delays and dropouts

Networked Control Systems (NCS) are systems in which serial communication networks are used to exchange system information and control signals between various physical components of the systems that may be physically distributed. Major advantages of NCS include low cost, reduced weight and power requirements, simple installation and maintenance, and high reliability. Nonetheless, closing a control loop on a shared communication network introduces additional dynamics and constraints in the control problem. In addition to being bit-rate limited [1], [2], practical communitacion channels are commonly affected by packet dropouts and time delays, mainly due to transmission errors and waiting times to access the medium; see, e.g., [3]-[5] and the many references therein

Control óptimo-L2 basado en red mediante funcionales de Lyapunov-Krasovskii

En el presente trabajo se estudia el control ́optimo con rechazo de perturbacionesL2para sistemas lineales controlados a trav ́esde red. En estos sistemas el lazo de control se cierra utilizando una red de comunicaciones. Entre los problemas que introduce lared se encuentran posibles retrasos, en general aleatorios, as ́ı como p ́erdidas de paquetes. Desde un enfoque basado en funcionalesde Lyapunov- Krasovskii (LKF) se aborda el dise ̃no de controladores ́optimos que, dado un nivel deseado de atenuaci ́on de per-turbaciones, estabilicen el sistema minimizando a su vez un funcional de coste. En el art ́ıculo se desarrolla, en primer lugar, unaformulaci ́on y soluci ́on general para el problema. Posteriormente, se resuelve para un funcional de Lyapunov-Krasovskii particular.El comportamiento de los controladores obtenidos se compara con el dado por un control cl ́asico LQR en un escenario de controlde distancia en carretera.Copyrightc 2012 CEA. Publicado por Elsevier Espa ̃na, S.L. Todos los derechos reservadosCICYT (DPI2010-19154)a Comision Europea (EC) (FeedNetBack Project, grant ´ agreement 223866

Wheat gluten protein hydrolysates anti-inflammatory study

Motivation: It is known that some peptides have bioactive properties, anticarcinogenic, anti-inflammatory or antimicrobial among others. Lately, researches made in this area have been focused on vegetable sources peptides, which have shown a great capacity of having anti-inflammatory effects. Therefore, the aim of this investigation was to check wheat gluten hydrolysates anti-inflammatory capacities.Methods: 1) Wheat gluten was used as starting material, which was hydrolysated with two different enzymes each on their own, Alcalse 2.4L and Izyme AL during 1 and 2 hours respectively, taking samples each 15 minutes (named A0, A15, A30, A45, A60; I0, I15, I30, I45, I60, I75, I90, I105, I120). The hydrolysis grade was obtained using 2,4,6-trinitrobenzene sulfonic acid (TNBS) method. 2) In order to determine their immunommodulatory capacity, the inhibitory effect of each sample was tested among chronic inflammatory diseases pathways common enzymes: thrombin and angiotensin-converting enzyme (ECA). 3) Blood cells, monocytes, submitted to lipopolysaccharide (LPS) infection, were incubated for 24 hours with A45 and I90 at different concentrations (10µg/mL and 5µg/mL) for the purpose of seeing IL-1β, TNF-α (pro-inflammatory proteins) and IL-10 (anti-inflammatory protein), cytokines genes expression change; studied by Q-PCR.Results & Conclusions: 1) The more was the time that were being hydrolysed, the bigger was the hydrolysis grade, reaching a maximum of 36% of it with Alcalase 2.4.L and a 11,869% with Izyme. 2) The hydrolysates named as A45 and I90 were the ones that shown the most effective inhibitory effect above inflammatory enzymes; their physicochemical features should be studied for understanding it. 3)The hydrolysates chosen in the enzymatic tests (A45 and I90) showed to have a anti-inflammatory activity potential on cells, since in most cases they tend to repress pro-inflammatory genes expression (TNF-α and IL-1β) and enhanced the expression of other anti-inflammatory cytokines such as IL-10 (in all cases). Therefore, this study reveals that the inclusion of wheat gluten protein hydrolysates on our diets could help in the treatment of inflammatory diseases

Recent developments in financing and bank lending to the non-financial private sector

Artículo de revistaThis is the first of a series of analytical articles that will examine, on a half-yearly basis, recent developments in funds raised by the Spanish non-financial private sector and resident deposit institutions’ credit exposure to the sector. In the early months of 2019, the conditions of access to bank finance for Spanish firms and households remained highly accommodative; however, after several years in which these conditions had gradually eased, signs are now emerging that suggest that this tendency may be coming to an end. Nevertheless, deposit institutions’ total outstanding credit exposure to the non-financial private sector continued to decline in 2019 Q1 (2.1% year-on-year). The NPL ratio also continued to fall

Absorptive capacity and value in the banking industry: A multiple mediation model

Firms continually look new ways to get the best results. This study focuses on the relationship between absorptive capacity (ACAP) and value, proposing a multiple mediation model to analyze this relationship. The study's contribution to the literature is to examine empirically, and in greater depth the antecedents and determinants of this variable. Thus, the research fills a gap in the literature through the analysis of the mediating role of knowledge stock (KS) and knowledge application (KA). This study applies variance-based structural equation modeling via partial least squares to a sample of 151 branch office managers from the Spanish banking industry. The results show that both the direct effect and indirect effect, through the mediation of KS and KA, are significant in the relationship between ACAP and valu

Detection and mapping of burnt areas from time series of MODIS-derived NDVI data in a Mediterranean region

Moderate resolution remote sensing data, as provided by MODIS, can be used to detect and map active or past wildfires from daily records of suitable combinations of reflectance bands. The objective of the present work was to develop and test simple algorithms and variations for automatic or semiautomatic detection of burnt areas from time series data of MODIS biweekly vegetation indices for a Mediterranean region. MODIS-derived NDVI 250m time series data for the Valencia region, East Spain, were subjected to a two-step process for the detection of candidate burnt areas, and the results compared with available fire event records from the Valencia Regional Government. For each pixel and date in the data series, a model was fitted to both the previous and posterior time series data. Combining drops between two consecutive points and 1-year average drops, we used discrepancies or jumps between the pre and post models to identify seed pixels, and then delimitated fire scars for each potential wildfire using an extension algorithm from the seed pixels. The resulting maps of the detected burnt areas showed a very good agreement with the perimeters registered in the database of fire records used as reference. Overall accuracies and indices of agreement were very high, and omission and commission errors were similar or lower than in previous studies that used automatic or semiautomatic fire scar detection based on remote sensing. This supports the effectiveness of the method for detecting and mapping burnt areas in the Mediterranean region.This work was supported by the research projects FEEDBACK (CGL2011-30515- C02-01), funded by the Spanish Ministry of Innovation and Science, CASCADE (GA283068), funded by European Commission under the Seventh Framework Program, and GVPRE/2008/310, funded by the Valencia Regional Government (Generalitat Valenciana)

Numerical analysis for design of bioinspired ceramic modular armors for ballistic protections

[EN] The exigent requirements for personal protections in terms of energy absorption and ergonomics have led to increasing interest in bioinspired protections. This work focuses on the numerical analysis of ballistic behavior of different bioinspired geometries under impact loadings. Ceramic armors based on ganoid fish scales (the type exhibited by gars, bichirs and reedfishes), placoid fish scales (characterizing sharks and rays) and armadillo natural protection have been considered. Different impact conditions are studied, including perpendicular and oblique impacts to surface protection, different yaw angle, and multiple impacts. Main conclusion is related to the improved efficiency of modular armors against multiple shots exhibiting more localized damage and crack arrest properties. Moreover, its potential ergonomic is a promising characteristic justifying a deeper study.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work has been carried out within the framework of the research program Juan de la Cierva Incorporacion 2015, and research projects DPI2017-88166-R, and RTC-2015-3887-8 of FEDER program financed by the Ministerio de Economia, Industria y Competitividad of Spain. The support of the Generalitat Valenciana, Programme PROMETEO 2016/007 is also acknowledged.González Albuixech, VF.; Rodríguez-Millán, M.; Ito, T.; Loya, JA.; Miguélez, MH. (2019). Numerical analysis for design of bioinspired ceramic modular armors for ballistic protections. International Journal of Damage Mechanics. 28(6):815-837. https://doi.org/10.1177/1056789518795203S815837286Chen, I. H., Kiang, J. H., Correa, V., Lopez, M. I., Chen, P.-Y., McKittrick, J., & Meyers, M. A. (2011). 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