307 research outputs found
Effects of Steady Flow on Magnetoacoustic-Gravity Surface Waves: I. The Weak Field Case
Magnetoacoustic gravity (MAG) waves have been studied for some time. In this article, we investigate the effect that a shear flow at a tangential discontinuity embedded in a gravitationally stratified and magnetised plasma has on MAG surface waves. The dispersion relation found is algebraically analogous to the relation of the non-flow cases obtained by Miles and Roberts (Solar Phys.141, 205, 1992), except for the introduction of a Doppler-shifted frequency for the eigenvalue. This feature, however, introduces rather interesting physics, including the asymmetric presence of forward- and backward-propagating surface waves. We find that increasing the equilibrium flow speed leads to a shift in the permitted regions of propagation for surface waves. For most wave number combinations this leads to the fast mode being completely removed, as well as more limited phase speed regimes for slow-mode propagation. We also find that upon increasing the flow, the phase speeds of the backward propagating waves are increased. Eventually, at high enough flow speeds, the wave’s direction of propagation is reversed and is in the positive direction. However, the phase speed of the forward-propagating wave remains mainly the same. For strong enough flows we find that the Kelvin–Helmholtz instability can also occur when the forward- and backward-propagating modes couple
Provenance and transport of supraglacial debris revealed by variations in debris geochemistry on Khumbu Glacier, Nepal Himalaya
The origin of supraglacial debris covers is often conceptualised as the formation of a surface lag by melt-out of englacial debris from slow-moving ice, where complexity arises from feedback between debris thickness and sub-debris ice melt. Here, we examine the origin of a debris cover from the perspective of debris provenance and changing tributary supply in a high-elevation compound valley glacier. Geochemical analysis of 11 major elements in 21 debris samples from six tributaries of Khumbu Glacier (Nepal) shows unambiguous statistical differentiation of debris sources reflecting lithological differences between tributary catchments. Twenty-four samples from transects across the ablation area are partitioned according to their source areas using the FR2000 sediment unmixing model. We estimate the age of ice at each transect using a higher order ice flow model. The results show greater proportions of debris from lateral tributaries in downglacier locations that have experienced longer flowline histories. More recently, ice from the Main Himalayan Divide (Western Cwm) has become relatively more important. This suggests a change in the state of the lower glacier's structure depending on the relative ice discharges of lateral and divide sources. Ice flux from lower elevation tributaries was more important probably prior to a weakening of the Indian Summer Monsoon at around 1420 CE. The lower elevation tributaries lie within the range of late Holocene equilibrium line altitude variation and therefore respond most sensitively to climatic drivers of the glacier's flow structure. Negative glacier mass balance since around 1900 CE caused tributary glaciers to detach and high-elevation catchments to re-establish as the dominant ice source to Khumbu Glacier
Forced Stratified Turbulence: Successive Transitions with Reynolds Number
Numerical simulations are made for forced turbulence at a sequence of
increasing values of Reynolds number, R, keeping fixed a strongly stable,
volume-mean density stratification. At smaller values of R, the turbulent
velocity is mainly horizontal, and the momentum balance is approximately
cyclostrophic and hydrostatic. This is a regime dominated by so-called pancake
vortices, with only a weak excitation of internal gravity waves and large
values of the local Richardson number, Ri, everywhere. At higher values of R
there are successive transitions to (a) overturning motions with local
reversals in the density stratification and small or negative values of Ri; (b)
growth of a horizontally uniform vertical shear flow component; and (c) growth
of a large-scale vertical flow component. Throughout these transitions, pancake
vortices continue to dominate the large-scale part of the turbulence, and the
gravity wave component remains weak except at small scales.Comment: 8 pages, 5 figures (submitted to Phys. Rev. E
Resonantly damped surface and body MHD waves in a solar coronal slab with oblique propagation
The theory of magnetohydrodynamic (MHD) waves in solar coronal slabs in a
zero- configuration and for parallel propagation of waves does not allow
the existence of surface waves. When oblique propagation of perturbations is
considered both surface and body waves are able to propagate. When the
perpendicular wave number is larger than a certain value, the body kink mode
becomes a surface wave. In addition, a sausage surface mode is found below the
internal cut-off frequency. When non-uniformity in the equilibrium is included,
surface and body modes are damped due to resonant absorption. In this paper,
first, a normal-mode analysis is performed and the period, the damping rate,
and the spatial structure of eigenfunctions are obtained. Then, the
time-dependent problem is solved, and the conditions under which one or the
other type of mode is excited are investigated.Comment: 19 pages, 9 figures, accepted for publication in Solar Physic
Modelling the bimodal distribution of indoor gamma-ray dose-rates in Great Britain
Gamma radiation from naturally occurring sources (including directly ionizing cosmic-rays) is a major component of background radiation. An understanding of the magnitude and variation of doses from these sources is important, and the ability to predict them is required for epidemiological studies. In the present paper, indoor measurements of naturally occurring gamma-rays at representative locations in Great Britain are summarized. It is shown that, although the individual measurement data appear unimodal, the distribution of gamma-ray dose-rates when averaged over relatively small areas, which probably better represents the underlying distribution with inter-house variation reduced, appears bimodal. The dose-rate distributions predicted by three empirical and geostatistical models are also bimodal and compatible with the distributions of the areally averaged dose-rates. The distribution of indoor gamma-ray dose-rates in the UK is compared with those in other countries, which also tend to appear bimodal (or possibly multimodal). The variation of indoor gamma-ray dose-rates with geology, socio-economic status of the area, building type, and period of construction are explored. The factors affecting indoor dose-rates from background gamma radiation are complex and frequently intertwined, but geology, period of construction, and socio-economic status are influential; the first is potentially most influential, perhaps, because it can be used as a general proxy for local building materials. Various statistical models are tested for predicting indoor gamma-ray dose-rates at unmeasured locations. Significant improvements over previous modelling are reported. The dose-rate estimates generated by these models reflect the imputed underlying distribution of dose-rates and provide acceptable predictions at geographical locations without measurements
B-cell dysregulation in Crohn's disease is partially restored with infliximab therapy
Background: B-cell depletion can improve a variety of chronic inflammatory diseases, but does not appear beneficial for patients with Crohn's disease. Objective: To elucidate the involvement of B cells in Crohn's disease, we here performed an 'in depth' analysis of intestinal and blood B-cells in this chronic inflammatory disease. Methods: Patients with Crohn's disease were recruited to study B-cell infiltrates in intestinal biopsies (n = 5), serum immunoglobulin levels and the phenotype and molecular characteristics of blood B-cell subsets (n = 21). The effects of infliximab treatment were studied in 9 patients. Results: Granulomatous tissue showed infiltrates of B lymphocytes rather than Ig-secreting plasma cells. Circulating transitional B cells and CD21low B cells were elevated. IgM memory B cells were reduced and natural effector cells showed decreased replication histories and somatic hypermutation (SHM) levels. In contrast, IgG and IgA memory B cells were normally present and their Ig gene transcripts carried increased SHM levels. The numbers of transitional and natural effector cells were normal in patients who responded clinically well to infliximab. Conclusions: B cells in patients with Crohn's disease showed signs of chronic stimulation with localization to granulomatous tissue and increased molecular maturation of IgA and IgG. Therapy with TNFα-blockers restored the defect in IgM memory B-cell generation and normalized transitional B-cell levels, making these subsets candidate markers for treatment monitoring. Together, these results suggest a chronic, aberrant B-cell response in patients with Crohn's disease, which could be targeted with new therapeutics that specifically regulate B-cell function
Tight-binding parameters for charge transfer along DNA
We systematically examine all the tight-binding parameters pertinent to
charge transfer along DNA. The molecular structure of the four DNA bases
(adenine, thymine, cytosine, and guanine) is investigated by using the linear
combination of atomic orbitals method with a recently introduced
parametrization. The HOMO and LUMO wavefunctions and energies of DNA bases are
discussed and then used for calculating the corresponding wavefunctions of the
two B-DNA base-pairs (adenine-thymine and guanine-cytosine). The obtained HOMO
and LUMO energies of the bases are in good agreement with available
experimental values. Our results are then used for estimating the complete set
of charge transfer parameters between neighboring bases and also between
successive base-pairs, considering all possible combinations between them, for
both electrons and holes. The calculated microscopic quantities can be used in
mesoscopic theoretical models of electron or hole transfer along the DNA double
helix, as they provide the necessary parameters for a tight-binding
phenomenological description based on the molecular overlap. We find that
usually the hopping parameters for holes are higher in magnitude compared to
the ones for electrons, which probably indicates that hole transport along DNA
is more favorable than electron transport. Our findings are also compared with
existing calculations from first principles.Comment: 15 pages, 3 figures, 7 table
Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection
Observation of Orbitally Excited B_s Mesons
We report the first observation of two narrow resonances consistent with
states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar
collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the
Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed
as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+,
\bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1})
= 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.Comment: Version accepted and published by Phys. Rev. Let
Growing Up in Poor Neighbourhoods:The Significance of Class and Place in the Extended Transitions of ‘Socially Excluded’Young Adults
- …