Fuzzy logic as a decision-making support system for the indication of bariatric surgery based on an index (OBESINDEX) generated by the association between body fat and body mass index

Background: A Fuzzy Obesity Index (OBESINDEX) for use as an alternative in bariatric surgery indication (BSI) is presented. The search for a more accurate method to evaluate obesity and to indicate a better treatment is important in the world health context. BMI (body mass index) is considered the main criteria for obesity treatment and BSI. Nevertheless, the fat excess related to the percentage of Body Fat (%BF) is actually the principal harmful factor in obesity disease that is usually neglected. This paper presents a new fuzzy mechanism for evaluating obesity by associating BMI with %BF that yields a fuzzy obesity index for obesity evaluation and treatment and allows building up a Fuzzy Decision Support System (FDSS) for BSI.

Methods: Seventy-two patients were evaluated for both BMI and %BF. These data are modified and treated as fuzzy sets. Afterwards, the BMI and %BF classes are aggregated yielding a new index (OBESINDEX) for input linguistic variable are considered the BMI and %BF, and as output linguistic variable is employed the OBESINDEX, an obesity classification with entirely new classes of obesity in the fuzzy context as well is used for BSI.

Results: There is a gradual, smooth obesity classification and BSI when using the proposed fuzzy obesity index when compared with other traditional methods for dealing with obesity.

Conclusion: The BMI is not adequate for surgical indication in all the conditions and fuzzy logic becomes an alternative for decision making in bariatric surgery indication based on the OBESINDEX

Preliminary checklist of the Cerambycidae, Disteniidae, and Vesperidae (Coleoptera) of Peru

A preliminary checklist of the Cerambycidae, Disteniidae, and Vesperidae (Coleoptera) of Peru is presented. Within Cerambycidae, we record five subfamilies, 55 tribes, 345 genera and subgenera, and 714 species. Within Disteniidae, we record one tribe, six genera, and 11 species. We also record one subfamily, one tribe, one genus, and two species within Vesperidae. Four new country records are recorded: one species in the tribe Anacolini (Cerambycidae: Prioninae): Cycloprionus flavus Tippmann, 1953; and three species in the tribe Onciderini (Cerambycidae: Lamiinae): Cacostola simplex (Pascoe, 1859); Marensis simplex (Bates, 1865); Trachysomus cavigibba Martins, 1975. In addition, 161 species recorded are known only from Peru

Quantum simulation of Anderson and Kondo lattices with superconducting qubits

We introduce a mapping between a variety of superconducting circuits and a family of Hamiltonians describing localized magnetic impurities interacting with conduction bands. This includes the Anderson model, the single impurity one- and two-channel Kondo problem, as well as the 1D Kondo lattice. We compare the requirements for performing quantum simulations using the proposed circuits to those of universal quantum computation with superconducting qubits, singling out the specific challenges that will have to be addressed.Comment: Longer versio

Dualities in Spin Ladders

We introduce a set of discrete modular transformations $T_\ell,U_\ell$ and $S_\ell$ in order to study the relationships between the different phases of the Heisenberg ladders obtained with all possible exchange coupling constants. For the 2 legged ladder we show that the $RVB$ phase is invariant under the $S_\ell$ transformation, while the Haldane phase is invariant under $U_\ell$. These two phases are related by $T_\ell$. Moreover there is a "mixed" phase, that is invariant under $T_\ell$, and which under $U_\ell$ becomes the RVB phase, while under $S_\ell$ becomes the Haldane phase. For odd ladders there exists only the $T_\ell$ transformation which, for strong coupling, maps the effective antiferromagnetic spin 1/2 chain into the spin 3/2 chain.Comment: REVTEX file, 5 pages, 2 EPS figure

The African hind's (Cephalopholis taeniops, serranidae) use of artificial reefs off Sal Island (Cape Verde): a preliminary study based on acoustic telemetry

The African hind Cephalopholis taeniops (Valenciennes, 1828) is one of the most important commercial demersal species caught in the Cape Verde archipelago. The species is closely associated with hard substrate and is one of the main attractions for SCUBA divers. In January 2006 a former Soviet fishing vessel - the Kwarcit - was sunk off Santa Maria Bay (Sal Island). Young C. taeniops are commonly observed in this artificial reef (AR). In order to investigate the species' use of the AR, 4 specimens were captured and surgically implanted underwater with Vemco brand acoustic transmitters. The fish were monitored daily with an active telemetry receiver for one week after release. Simultaneously, an array of 3 passive VR2 / VR2W receivers was set for 63 days, registering data that allowed an analysis of spatial, daily and short term temporal activity patterns. The results showed site fidelity to the AR, with no migrations to the nearby natural reef. The method used allowed to register a consistent higher activity during daytime and a preference for the area opposite the dominant current

THE IMPORTANCE OF CONSISTENT KINEMATIC DATA IN THE INVERSEDYNAMIC ANALYSIS OF BIOMECHANICAL MODELS

INTRODUCTION: The evaluation of the muscular actions and internal forces of human articular joints is of major importance in different areas of medicine, sports, physical rehabilitation or biomedical engineering. There is no experimental methodology that can directly measure these forces. Among the numerical procedures that can be applied, inverse dynamics based methods are still the most commonly used numerical tools. Their use requires that the kinematics of human motion, i.e., the positions, velocities and accelerations of the anatomical points, be known in advance. This is obtained by standard reconstruction methods based on the DLT technique (Aziz and Karara, 1971). Moreover, the equations of motion for the system must be associated to a biomechanical model (Celigueta, 1996; Silva et al., 1997). The muscle action may be obtained by having each particular group of muscles, defined as those with similar functions and common anatomical insertions, modeled independently and included in the biomechanical model (An et al., 1995). This leads to an indeterminate problem, in terms of the unknown forces, that can be solved using the optimization theory (Pedotti et al., 1978). Alternatively, the actions of the different muscle groups can be lumped as moments about anatomical joints leading to a determinate inverse dynamics problem (Winter, 1991). Regardless of the biomechanical model used or of the way the muscle actions are described, the results obtained from the inverse dynamic analysis are related to the quality of the kinematic data supplied. The problem of the consistency of this kinematic data with respect to the biomechanical model used is addressed in this work, it being shown that the quality of the inverse dynamics analysis results is highly dependent on the data kinematic consistency

Usos actuales de los SIG para la ingeniería civil en Colombia

This document presents and reviews the GIS (Geographic Information System) in Colombia and its possible current uses in civil engineering. Since a model with georeferenced graphic elements (maps) with additional information associated with a database is a very complete design tool, it facilitates engineering analysis to carry out effective construction projects.Este documento presenta y reseña los SIG (Sistema de Información Geográfica) en Colombia y sus posibles usos actuales en la ingeniería civil. Ya que un modelo con elementos gráficos geo referenciados (mapas) que cuenta con información adicional asociada a una base de datos conforma una herramienta de diseño muy completa, la misma facilita a la ingeniería la realización de análisis con el fin de realizar proyectos constructivos efectivos

On the nonlinear stability of mKdV breathers

A mathematical proof for the stability of mKdV breathers is announced. This proof involves the existence of a nonlinear equation satisfied by all breather profiles, and a new Lyapunov functional which controls the dynamics of small perturbations and instability modes. In order to construct such a functional, we work in a subspace of the energy one. However, our proof introduces new ideas in order to attack the corresponding stability problem in the energy space. Some remarks about the sine-Gordon case are also considered.Comment: 7 p

The case for early use of rapid whole-genome sequencing in management of critically ill infants: late diagnosis of Coffin-Siris syndrome in an infant with left congenital diaphragmatic hernia, congenital heart disease, and recurrent infections.

Congenital diaphragmatic hernia (CDH) results from incomplete formation of the diaphragm leading to herniation of abdominal organs into the thoracic cavity. CDH is associated with pulmonary hypoplasia, congenital heart disease, and pulmonary hypertension. Genetically, it is associated with aneuploidies, chromosomal copy-number variants, and single gene mutations. CDH is the most expensive noncardiac congenital defect. Management frequently requires implementation of extracorporeal membrane oxygenation (ECMO), which increases management expenditures 2.4-3.5-fold. The cost of management of CDH has been estimated to exceed $250 million per year. Despite in-hospital survival of 80%-90%, current management is imperfect, as a great proportion of surviving children have long-term functional deficits. We report the case of a premature infant prenatally diagnosed with CDH and congenital heart disease, who had a protracted and complicated course in the intensive care unit with multiple surgical interventions, including postcardiac surgery ECMO, gastrostomy tube placement with Nissen fundoplication, tracheostomy for respiratory failure, recurrent infections, and developmental delay. Rapid whole-genome sequencing (rWGS) identified a de novo, likely pathogenic, c.3096_ 3100delCAAAG (p.Lys1033Argfs*32) variant in ARID1B, providing a diagnosis of Coffin-Siris syndrome. Her parents elected palliative care and she died later that day

Practical Spectrophotometric Assay for the \u3cem\u3edapE\u3c/em\u3e-Encoded \u3cem\u3eN\u3c/em\u3e-Succinyl-L,L-Diaminopimelic Acid Desuccinylase, a Potential Antibiotic Target

A new enzymatic assay for the bacterial enzyme succinyl-diaminopimelate desuccinylase (DapE, E.C. 3.5.1.18) is described. This assay employs N6-methyl-N2-succinyl-L,L-diaminopimelic acid (N6-methyl-L,L-SDAP) as the substrate with ninhydrin used to detect cleavage of the amide bond of the modified substrate, wherein N6-methylation enables selective detection of the primary amine enzymatic product. Molecular modeling supported preparation of the mono-N6-methylated-L,L-SDAP as an alternate substrate for the assay, given binding in the active site of DapE predicted to be comparable to the endogenous substrate. The alternate substrate for the assay, N6-methyl-L,L-SDAP, was synthesized from the tert-butyl ester of Boc-L-glutamic acid employing a Horner-Wadsworth-Emmons olefination followed by an enantioselective reduction employing Rh(I)(COD)(S,S)-Et-DuPHOS as the chiral catalyst. Validation of the new ninhydrin assay was demonstrated with known inhibitors of DapE from Haemophilus influenza (HiDapE) including captopril (IC50 = 3.4 [± 0.2] μM, 3-mercaptobenzoic acid (IC50 = 21.8 [±2.2] μM, phenylboronic acid (IC50 = 316 [± 23.6] μM, and 2-thiopheneboronic acid (IC50 = 111 [± 16] μM. Based on these data, this assay is simple and robust, and should be amenable to high-throughput screening, which is an important step forward as it opens the door to medicinal chemistry efforts toward the discovery of DapE inhibitors that can function as a new class of antibiotics