One and a Half Decades of Apartment Loss and Condominium Growth: Changes in Chicago's Residential Building Stock

CURL researchers used data from the Cook County Assessor to document the decline in Chicago apartments and growth in condominium units from 1989 to 2004 in the following report. The analysis that follows uses parcel level data collected for the purpose of assessing property taxes by the Cook County Tax Assessor in 1989-1990, 1995-1997, 2002 and 2004.

The Earth isn’t Flat, and Neither is Illinois’— or any other state’s— Income Tax

In her book, Flat Earth: The history of an infamous idea, 1 Christine Garwood explains that from medieval times, long predating Christopher Columbus’ famous voyages, educated people knew that the earth was not flat. Nevertheless, the flat earth myth persisted for centuries and even has some, possibly (non)ironic, modern adherents (see R. Brazil 2020).2 Simplistic and wrong-headed ideas often persist despite unassailable evidence to the contrary and a consensus among those who have carefully considered the question. The exaggerated dichotomy between “flat tax rate” and “graduated tax rate” states is a current manifestation of this phenomenon. Many members of the public, and some people on the fringes of the policymaking world, overstate the differences between these cases and conclude that only graduated rate states can deliver “progressive” tax policy that results in tax liabilities rising with incomes.3 Tax policy professionals realize that tax liabilities depend not only on the structure of tax rates but also on many other facets of the tax system including the definition of the tax base and myriad rules about tax credits, exemptions, and interactions between different tax systems (e.g. state and federal tax systems).4 In this short paper, we demonstrate that tax rates are just one of many determinants of state personal income tax liability. We also quantify the various ways in which tax liability can vary across states with a consistently defined measure of incomeOpe

One and a Half Decades of Apartment Loss and Condominium Growth: Changes in Chicago\u27s Residential Building Stock

We use data from the Cook County Assessor to document the decline in Chicago apartments and growth in condominium units from 1989 to 2004. While the total number of housing units in Chicago remained approximately constant at a little over one million, we find that at least 44,637 and perhaps as many as 97,894 apartment units were removed from Chicago’s housing stock during this period. Over the same period 102,408 condominium units have been added to the housing stock. We provide tables and maps that show the changes by in small apartments (less than six units), large apartments (7+ units) and condominiums by community area. Loss of small and large apartment buildings has been widespread across the entire city. Condominium growth has been most intense on the Northeast, Near South and Near West Sides. Some, but not all, of the community areas that lost large numbers of apartments gained condominiums. On average, across the city as a whole, for each 1,000 additional condominium units a community area gained, it lost 27 small apartment buildings and about 6 large apartment buildings

What Policymakers Should Know About the Fiscal Impact of COVID-19 on Illinois

We model the fiscal impacts of the COVID-19 pandemic and stay at home orders on Illinois’ fiscal situation. Prominent forecasters’ recently published estimates range from short and modest declines in U.S. GDP to declines of almost 6%. We model the impact of these economic disruptions on the revenues of the individual income, corporate income, and sales taxes considering what we know about the past history of the revenue sources. We estimate revenue losses from $6.4 billion in the severe pandemic scenario to$1.9 billion in the low severity scenario. We also expect large increases in public health expenditures but a modest impact on Illinois’ fiscal situation since these expenditures are a small portion of the budget. Over the next several years, annual Medicaid expenditures could increase by $4 to$5 billion (21% to 26%). We expect increases in expenditures on human services as economic pressures require residents impacted by the pandemic to rely on these services. Potential declines in the value of public pension funds’ assets could result in increased unfunded liabilities and required state contributions. However, these increased contributions would be phased in gradually due to “asset smoothing,” and immediate fiscal effects would be modest. Local governments with a sales tax are likely to see immediate revenue shortfalls resulting from the sharp COVID-19 related economic downturn. Economic disruption may result in decreased property tax collections, but these impacts would lag significantly. To date, federal responses have been significant but are unlikely to fully insulate Illinois from the fiscal damage.Ope

Ciliary Abnormalities Due to Defects in the Retrograde Transport Protein DYNC2H1 in Short-Rib Polydactyly Syndrome

The short-rib polydactyly (SRP) syndromes are a heterogenous group of perinatal lethal skeletal disorders with polydactyly and multisystem organ abnormalities. Homozygosity by descent mapping in a consanguineous SRP family identified a genomic region that contained DYNC2H1, a cytoplasmic dynein involved in retrograde transport in the cilium. Affected individuals in the family were homozygous for an exon 12 missense mutation that predicted the amino acid substitution R587C. Compound heterozygosity for one missense and one null mutation was identified in two additional nonconsanguineous SRP families. Cultured chondrocytes from affected individuals showed morphologically abnormal, shortened cilia. In addition, the chondrocytes showed abnormal cytoskeletal microtubule architecture, implicating an altered microtubule network as part of the disease process. These findings establish SRP as a cilia disorder and demonstrate that DYNC2H1 is essential for skeletogenesis and growth

Participatory Augering: A methodology for challenging perceptions of archaeology and landscape change

Public engagement is a significant feature of twenty-first-century archaeological practice. While more diverse audiences are connecting with the discipline in a multitude of ways, public perceptions of archaeology are still marred by stereotypes. Community excavations of ‘sites’ to discover ‘treasures’ which tell us about the ‘past’ overshadow other forms of public research output and hinder the potential of the discipline to contribute to contemporary society more widely. This paper proposes participatory augering as an active public engagement method that challenges assumptions about the nature of archaeological practice by focusing on interpretation at a landscape-scale. Through exploration of recent participatory augering research by the REFIT Project and Environmental Archaeologist Mike Allen, this paper demonstrates how the public can contribute to active archaeological research by exploring narratives of landscape change. Evaluation of the existing case studies reflects the potential of the approach to engage audiences with new archaeological methods and narratives which have the potential to transform perceptions of the discipline and, through knowledge exchange, drive community-led contributions to contemporary landscape management

Expression of Glucose Transporters in the Prelaminar Region of the Optic-Nerve Head of the Pig as Determined by Immunolabeling and Tissue Culture

Background: To develop the use of cultured tissue of the prelaminar optic nerve of the pig to explore possible alterations of the astrocyte-axon metabolic pathways in glaucoma, we map the distribution of the glucose transporters GLUT1 and GLUT3 in fresh and cultured tissue.Methods: We monitor cell survival in cultures of the prelaminar optic-nerve tissue, measuring necrosis and apoptosis markers biochemically as well as morphologically, and establish the presence of the glucose transporters GLUT1 and GLUT3. We map the distribution of these transporters with immunolabeling in histological sections of the optic nerve using confocal and electronic transmission microscopy.Results: We find that the main death type in prelaminar culture is apoptosis. Caspase 7 staining reveals an increment in apoptosis from day 1 to day 4 and a reduction from day 4 to day 8. Western blotting for GLUT1 shows stability with increased culture time. CLSM micrographs locate GLUT1 in the columnar astrocytes and in the area of axonal bundles. Anti-GLUT3 predominantly labels axonal bundles. TEM immunolabeling with colloidal gold displays a very specific distribution of GLUT-1 in the membranes of vascular endothelial cells and in periaxonal astrocyte expansions. The GLUT-3 isoform is observed with TEM only in axons in the axonal bundles.Conclusions: Tissue culture is suitable for apoptosis-induction experiments. The results suggest that glucose is transported to the axonal cleft intracytoplasmically and delivered to the cleft by GLUT1 transporters. As monocarboxylate transporters have been reported in the prelaminar region of the optic-nerve head, this area is likely to use both lactate and glucose as energy sources.This work was supported by a grant from the Consejería de Salud, Junta de Andalucia, Spain, Project PI-0655-2013

An Analysis of the Employment Effects of the Washington High Technology Business and Occupation (B&O) Tax Credit: Technical Report

This paper estimates the effects of an R&D tax credit in the state of Washington on job creation. The research uses micro-data on the job creation and tax credits received by individual firms in the state of Washington from 2004 to 2009. We correct for the endogeneity of R&D tax credits received by individual firms by using instrumental variables based in part on national industry factor shares for R&D. We estimate that this tax credit created jobs, but at a high cost. The cost per job-year created is estimated to be between $40,000 and$50,000. The credit was so high cost in part because the credit was non-refundable. As a result, about one-quarter of the firms receiving credits were maxed out on credit eligibility, so that the credit provided no marginal incentive for additional R&D spending or job creation

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge

There is tremendous potential for genome sequencing to improve clinical diagnosis and care once it becomes routinely accessible, but this will require formalizing research methods into clinical best practices in the areas of sequence data generation, analysis, interpretation and reporting. The CLARITY Challenge was designed to spur convergence in methods for diagnosing genetic disease starting from clinical case history and genome sequencing data. DNA samples were obtained from three families with heritable genetic disorders and genomic sequence data were donated by sequencing platform vendors. The challenge was to analyze and interpret these data with the goals of identifying disease-causing variants and reporting the findings in a clinically useful format. Participating contestant groups were solicited broadly, and an independent panel of judges evaluated their performance. RESULTS: A total of 30 international groups were engaged. The entries reveal a general convergence of practices on most elements of the analysis and interpretation process. However, even given this commonality of approach, only two groups identified the consensus candidate variants in all disease cases, demonstrating a need for consistent fine-tuning of the generally accepted methods. There was greater diversity of the final clinical report content and in the patient consenting process, demonstrating that these areas require additional exploration and standardization. CONCLUSIONS: The CLARITY Challenge provides a comprehensive assessment of current practices for using genome sequencing to diagnose and report genetic diseases. There is remarkable convergence in bioinformatic techniques, but medical interpretation and reporting are areas that require further development by many groups

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

Abdominal aortic aneurysm (AAA) is a common cause of morbidity and mortality and has a significant heritability. We carried out a genome-wide association discovery study of 1866 patients with AAA and 5435 controls and replication of promising signals (lead SNP with a p value < 1 × 10-5) in 2871 additional cases and 32,687 controls and performed further follow-up in 1491 AAA and 11,060 controls. In the discovery study, nine loci demonstrated association with AAA (p < 1 × 10-5). In the replication sample, the lead SNP at one of these loci, rs1466535, located within intron 1 of low-density-lipoprotein receptor-related protein 1 (LRP1) demonstrated significant association (p = 0.0042). We confirmed the association of rs1466535 and AAA in our follow-up study (p = 0.035). In a combined analysis (6228 AAA and 49182 controls), rs1466535 had a consistent effect size and direction in all sample sets (combined p = 4.52 × 10-10, odds ratio 1.15 [1.10-1.21]). No associations were seen for either rs1466535 or the 12q13.3 locus in independent association studies of coronary artery disease, blood pressure, diabetes, or hyperlipidaemia, suggesting that this locus is specific to AAA. Gene-expression studies demonstrated a trend toward increased LRP1 expression for the rs1466535 CC genotype in arterial tissues; there was a significant (p = 0.029) 1.19-fold (1.04-1.36) increase in LRP1 expression in CC homozygotes compared to TT homozygotes in aortic adventitia. Functional studies demonstrated that rs1466535 might alter a SREBP-1 binding site and influence enhancer activity at the locus. In conclusion, this study has identified a biologically plausible genetic variant associated specifically with AAA, and we suggest that this variant has a possible functional role in LRP1 expression