Social housing in the Dominican Republic, a study on thermal comfort

[EN] The accelerated growth of cities entails challenges in all sectors, and specifically, it has a close relationship with the construction sector. The Dominican Republic is a country where urban growth is increasing considerably, representing a problem of great magnitude in terms of the construction of social housing to reduce the housing deficit. In the social housing projects in Santo Domingo, the energy conditions are non-existent. There are no previous studies on the thermal comfort of those buildings. For this reason, this study seeks to analyze thermal comfort and energy efficiency in these types of housing through an energy simulation.The energy simulation is carried out through OpenStudio, which uses the Energy Plus calculation engine. A type of model was analyzed for the determination of temperatures and ranges of thermal comfort to evaluate its behavior for 24 hours in different months. The calculations obtained from the energy consumption due mainly to the variation of the comfort temperature indicate that the temperature variation is very similar in the selected months, with a maximum temperature of 27.3ºC in the hottest month and a minimum temperature of 26 .8ºC in the coldest month. Finally, due to the warm climate that prevails in the area, a high comfort temperature is recorded in these types of dwellings. To improve the comfort conditions in this type of dwelling, it is necessary to add thermal insulation and control the solar gains effectively.Acosta Medina, DT.; Quintana Gallardo, A.; Guillén Guillamón, IE. (2023). Social housing in the Dominican Republic, a study on thermal comfort. Editorial Universitat Politècnica de València. 668-677. https://doi.org/10.4995/VIBRArch2022.2022.1521266867

Cross - Language Information Retrieval Using Two Methods: LSI via SDD and LSI via SVD

This chapter presents a method for the recovery of bilingual information based on semidiscrete matrix decomposition (SDD); that is, the problem of retrieving information in two languages, Spanish and English, is studied when the queries are made only in Spanish. In it, four case studies that exhibit the performance of the use of the latent semantic index (LSI) via SDD method for cross-language information retrieval (CLIR) are displayed. Concurrently, these results are compared with those obtained by applying LSI via singular value decomposition (SVD). All experiments were performed from a bilingual database, built from the gospels of the Bible, which combines documents in Spanish and English. For this, a fusion strategy was used that increases the size of the database by 10%. It was found that in terms of errors, the methods are comparable, since equal results were obtained in 58.3% of the queries made. In addition, the methods presented a success rate of at least 65% in the task of retrieving relevant information in the two languages considered

Identification of a highly polymorphic tetranucleotide repeat locus (DXpS) at Xp and development of a DXpS/HUMARA biplex methylation-based PCR assay that enhances detection of X-chromosome inactivation

The methylation-based PCR assay at the polymorphic (CAG)n repeat in exon 1 of the human androgen receptor _AR_ gene (HUMARA) is a standard method for determination of the methylation state of alleles in active X (Xa) and inactive X (Xi) chromosomes. HUMARA assay is endowed with heterozygosity rates ~85% worldwide. This means that in a proportion of females it is uninformative. The HUMARA genotype is not neutral, being linked to Kennedy´s disease. Moreover, allele designation and quantification from trinucleotide repeats demand normalizing for minor (stutter) products differing from the original template by multiples of the repeat unit. Here, we report on the identification of a highly polymorphic tetranucleotide repeat (named DXpS) mapping to within a CpG island on Xp. This island is 191 bp downstream from the start of the repeat element, and contains sites for the HhaI, HpaII and BstUI methyl-sensitive restriction enzymes. We developed the DXpS and the HUMARA markers into a biplex methylation-based quantitative fluorescent PCR assay. For DXpS we observed twelve alleles with negligible stuttering. DXpS exhibited a heterozygosity rate of 87% (n = 60), matching that of HUMARA. The combined informativeness of the biplex assay was 98%. Random and nonrandom X-inactivation patterns inferred with DXpS in phenotypically normal females and haemophiliac females carrying a defective F8 gene were highly concordant (r^2^ = 0.96) with HUMARA patterns. DXpS represents a notable advancement in detecting X-chromosome inactivation due to the observed high rate of heterozygosity, negligible stuttering, concordance with HUMARA, and the apparent neutrality of allelic variants. Financial support: FAPESP (09/10615-7), FAPERJ, CNPq

Malocclusion and TMJ disorders in teenagers from private and public schools in Mexico City

Objective: To identify, among Mexican teenagers from public and private schools, the frequency, severity of maloc - clusion and orthodontic treatment needs, and their possible association with temporomandibular joint disorders. Material and Methods: Fifteen-year-old students were recruited from public and private schools. Clinical findings were registered as follows: oral hygiene status with the Oral Hygiene Index-Simplified, malocclusion using the Dental Aesthetic Index (DAI), and TMJ disorders following WHO criteria. Negative binomial and logistic regres - sion models were constructed for data analysis. Results: A total of 249 fifteen-year old students were included in the study . Conclusions: TMJ disorders and DAI scores were significantly associated. Screening/Diagnostic programs for ortho- dontic and TMJ-disorders are needed, to identify and offer treatment to teenagers with major malocclusion and TMJ/ muscle pain

Model Development for Bayesian Risk Assessment and Management of Supply Chains Impacted by COVID-19 and Other Converging Threats

COVID-19 has generated disruptions on supply chains across the world with impacts reflected in shortage, or delay of supplies, accompanied by strong shifts of demand for several economic sectors. Under such a disruption, the challenge is to address the social, environmental, and economic impacts on U.S. Supply Chain infrastructure, and identify critical nodes and processes in order to protect and restore the supply chains for an uninterrupted flow of supplies and materials critical to Homeland Security

Trisomy 21 alters DNA methylation in parent-of-origin-dependent and independent manners

The supernumerary chromosome 21 in Down syndrome differentially affects the methylation statuses at CpG dinucleotide sites and creates genome-wide transcriptional dysregulation of parental alleles, ultimately causing diverse pathologies. At present, it is unknown whether those effects are dependent or independent of the parental origin of the nondis-joined chromosome 21. Linkage analysis is a standard method for the determination of the parental origin of this aneuploidy, although it is inadequate in cases with deficiency of samples from the progenitors. Here, we assessed the reliability of the epigenetic 5(m)CpG imprints resulting in the maternally (oocyte)-derived allele methylation at a differentially methylated region (DMR) of the candidate imprinted WRB gene for asserting the parental origin of chromosome 21. We developed a methylation-sensitive restriction enzyme-specific PCR assay, based on the WRB DMR, across single nucleotide polymorphisms (SNPs) to examine the methylation statuses in the parental alleles. In genomic DNA from blood cells of either disomic or trisomic subjects, the maternal alleles were consistently methylated, while the paternal alleles were unmethylated. However, the supernumerary chromosome 21 did alter the methylation patterns at the RUNX1 (chromosome 21) and TMEM131 (chromosome 2) CpG sites in a parent-of-origin-independent manner. To evaluate the 5(m)CpG imprints, we conducted a computational comparative epigenomic analysis of transcriptome RNA sequencing (RNA-Seq) and histone modification expression patterns. We found allele fractions consistent with the transcriptional biallelic expression of WRB and ten neighboring genes, despite the similarities in the confluence of both a 17-histone modification activation backbone module and a 5-histone modification repressive module between the WRB DMR and the DMRs of six imprinted genes. We concluded that the maternally inherited 5(m)CpG imprints at the WRB DMR are uncoupled from the parental allele expression of WRB and ten neighboring genes in several tissues and that trisomy 21 alters DNA methylation in parent-of-origin-dependent and -independent manners

Malocclusion and TMJ disorders in teenagers from private and public schools in Mexico City

Objective: To identify, among Mexican teenagers from public and private schools, the frequency, severity of malocclusion and orthodontic treatment needs, and their possible association with temporomandibular joint disorders. Material and methods: Fifteen-year-old students were recruited from public and private schools. Clinical findings were registered as follows: oral hygiene status with the Oral Hygiene Index-Simplified, malocclusion using the Dental Aesthetic Index (DAI), and TMJ disorders following WHO criteria. Negative binomial and logistic regression models were constructed for data analysis. Results: A total of 249 fifteen-year old students were included in the study (118 female 47.4%). 68% had a DAI score ≤ 25 (minor or no occlusal anomalies), 18% scored 26-30 (mild anomalies), 7% scored 31-35 (evident anomalies), and 6% scored ≥ 36 (major malocclusion). The most frequent anomalies were dental crowding in 50%, maxillary dental irregularity in 44.6%, mandible irregularity in 41.2% and excessive maxillary overjet in 37.8%. Among the students, 26.1% had clicking/muscle or TMJ pain, of these 12.3% showed pain during palpation. OHI-S > 1 was found in 34% of the participants. The negative binomial model showed an association between DAI score and TMJ disorders (P=0.041). Also the logistic regression model showed an association between malocclusion (DAI>25) and TMJ disorders (OR=2.58, p=0.002). Malocclusion was associated also with poor oral hygiene (OR=1.65, p=0.007), and with attendance to public schools (OR=1.97, p=0.039). Conclusions: TMJ disorders and DAI scores were significantly associated. Screening/Diagnostic programs for orthodontic and TMJ-disorders are needed, to identify and offer treatment to teenagers with major malocclusion and TMJ/muscle pain

Pereira imaginada 2009 - 2014: cuadrante 2B

El grupo de investigación en Comunicación Educativa en la línea de investigación: La comunicación y la educación en procesos de transformación cultural, inició en junio de 1997 su recorrido investigativo sobre ciudad. A comienzos de 1999 la primera investigación culmina con el texto: ‘Imaginario Femenino y Ciudad’, editado por tercer mundo Editores de Bogotá (1999) en co- financiación con la Universidad Tecnológica de Pereira. Esta investigación se propuso como objetivo develar las maneras de usar y evocar la ciudad e indagar sobre la percepción que de ciudad tienen los ciudadanos de Pereira. En el año 2002 se publica el texto: ‘Modos de ver: Los Sentidos de la Comunicación Educativa (1990 – 2002)’, impreso en la editorial Papiro. Este texto recogió la producción investigativa realizada en la Maestría en Comunicación Educativa de la Universidad Tecnológica de Pereira entre los años 1990 y 2002, consignada en las tesis de grado. Con el objetivo de determinar el sentido de construcción del concepto Comunicación Educativa. En el primer semestre del 2004 se publicó el libro: ‘Paradoja de la ciudadanía en Pereira: Entre los Ciudadanos Jurídicos y los Itinerantes (2001 – 2003)’; editado por la Editorial Magisterio de Bogotá (2004). Indagó sobre el tipo de ciudadano que recrea la prensa local (Diario del Otún y La Tarde), y sus esquemas observacionales, con el objetivo de complejizar la categoría ciudadano-a, recreada a través de la prensa local de Pereira

Retos y perspectivas del derecho administrativo : segunda parte

Bajo la denominación de , la presente obra colectiva presenta las ponencias expuestas por los participantes en el Seminario que con el mismo nombre organizó la Facultad de Jurisprudencia de la Universidad del Rosario para conmemorar el décimo aniversario de la Maestría de Derecho Administrativo. El seminario tuvo como objetivos ofrecer una retrospectiva de la evolución histórica del derecho administrativo nacional y comparado con los ejes de internacionalización. Protección de los derechos y actuación administrativa y jurisdiccional: presentar una visión reflexiva acerca de los cambios ocurridos en los contenidos del derecho administrativo determinado por las transformaciones del Estado social y democrático de derecho; y mostrar las tendencias contemporáneas de construcción del derecho administrativo como respuesta a la globalización y la internacionalización