An annotated bibliography of the research on marine organisms and environments at Christmas Island and the Cocos (Keeling) Islands

Christmas Island and the Cocos (Keeling) Islands represent a unique marine biodiversity hotspot because of the overlap between two major biogeographic provinces (Indian and Pacific Ocean) and the high proportion of endemic species. In this paper, we compile existing scientific literature pertaining to marine organisms and environments at these islands to determine the current state of knowledge and identify major knowledge gaps. In total, 1066 studies have been published, including 582 peer-reviewed journal articles (55% of all publications), 332 reports, 141 books or book chapters, and 11 theses. These studies extend back to 1697, but most (83%) are post-1970. Seabirds have been the most studied group (43% of all publications), followed by land crabs (13%). There has been very little research on plankton (<0.3% of all studies), despite the diversity of marine species that have larval stages (including land crabs) and the importance of plankton to ecosystem function. Most invertebrate groups have received little attention or have not been studied. The taxonomic bias in marine research at these islands means that most of the invertebrates are yet to be documented. Some of these groups (e.g., Polychaeta, Copepoda, and anchialine fauna) are known for their high degree of endemism and are likely to contain new species, thereby increasing the biodiversity value of the islands. That whole families (even phyla) are yet to be studied highlights the infancy in some areas of marine research and adding to species lists for unstudied or understudied groups is one priority that would increase the conservation importance of these islands. Without this knowledge, the ability to monitor, detect or predict anthropogenic impacts on marine species is severely restricted, and therefore limits the development of management strategies aimed at conserving the unique marine biodiversity of these islands. Further studies on functional processes and research related directly to impacts are also needed. Increasing studies that directly relate to management questions will provide guidance to managers charged with protecting the environment. Improved decision making in conservation management will occur through increased directed research and monitoring

Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4- Dependent Visceral Hypersensitivity

Exposure to high-fat diet induces both, peripheral and central alterations in TLR4 expression. Moreover, functional TLR4 is required for the development of high-fat diet-induced obesity. Recently, central alterations in TLR4 expression have been associated with the modulation of visceral pain. However, it remains unknown whether there is a functional interaction between the role of TLR4 in diet-induced obesity and in visceral pain. In the present study we investigated the impact of long-term exposure to high-fat diet on visceral pain perception and on the levels of TLR4 and Cd11b (a microglial cell marker) protein expression in the prefrontal cortex (PFC) and hippocampus. Peripheral alterations in TLR4 were assessed following the stimulation of spleenocytes with the TLR4-agonist LPS. Finally, we evaluated the effect of blocking TLR4 on visceral nociception, by administering TAK-242, a selective TLR4-antagonist. Our results demonstrated that exposure to high-fat diet induced visceral hypersensitivity. In parallel, enhanced TLR4 expression and microglia activation were found in brain areas related to visceral pain, the PFC and the hippocampus. Likewise, peripheral TLR4 activity was increased following long-term exposure to high-fat diet, resulting in an increased level of pro-inflammatory cytokines. Finally, TLR4 blockage counteracted the hyperalgesic phenotype present in mice fed on high-fat diet. Our data reveal a role for TLR4 in visceral pain modulation in a model of diet-induced obesity, and point to TLR4 as a potential therapeutic target for the development of drugs to treat visceral hypersensitivity present in pathologies associated to fat diet consumption

Modelling mammalian energetics: the heterothermy problem

Global climate change is expected to have strong effects on the world’s flora and fauna. As a result, there has been a recent increase in the number of meta-analyses and mechanistic models that attempt to predict potential responses of mammals to changing climates. Many models that seek to explain the effects of environmental temperatures on mammalian energetics and survival assume a constant body temperature. However, despite generally being regarded as strict homeotherms, mammals demonstrate a large degree of daily variability in body temperature, as well as the ability to reduce metabolic costs either by entering torpor, or by increasing body temperatures at high ambient temperatures. Often, changes in body temperature variability are unpredictable, and happen in response to immediate changes in resource abundance or temperature. In this review we provide an overview of variability and unpredictability found in body temperatures of extant mammals, identify potential blind spots in the current literature, and discuss options for incorporating variability into predictive mechanistic models

THE COCHINEAL CREEPER AND THE FASCINATING GROSBEAK A RE-EXAMINATION OF SOME NAMES OF JOHN LATHAM

Volume: 110Start Page: 153End Page: 15

On the proposed suppression of all prior usages of generic and specific names of birds (Aves) by John Gould and others conventionally accepted as published in the Proceedings of the Zoological Society of London

Volume: 57Start Page: 113End Page: 11

The birds of the southern Coral Sea including observations by HMS Herald in 1858-60

Volume: 531-542Start Page: 237End Page: 26

Effect of harvesting at different stages of growth and long term storage on phenolics in sorghum stover

Studies changes in the concentrations and composition of phenolic compounds in component parts of different sorghum varieties harvested at different growth stages and also after long time storage

Protein Quality and the Protein to Carbohydrate Ratio within a High Fat Diet Influences Energy Balance and the Gut Microbiota In C57BL/6J Mice

peer-reviewedMacronutrient quality and composition are important determinants of energy balance and the gut microbiota. Here, we investigated how changes to protein quality (casein versus whey protein isolate; WPI) and the protein to carbohydrate (P/C) ratio within a high fat diet (HFD) impacts on these parameters. Mice were fed a low fat diet (10% kJ) or a high fat diet (HFD; 45% kJ) for 21 weeks with either casein (20% kJ, HFD) or WPI at 20%, 30% or 40% kJ. In comparison to casein, WPI at a similar energy content normalised energy intake, increased lean mass and caused a trend towards a reduction in fat mass (P = 0.08), but the protein challenge did not alter oxygen consumption or locomotor activity. WPI reduced HFD-induced plasma leptin and liver triacylglycerol, and partially attenuated the reduction in adipose FASN mRNA in HFD-fed mice. High throughput sequence-based analysis of faecal microbial populations revealed microbiota in the HFD-20% WPI group clustering closely with HFD controls, although WPI specifically increased Lactobacillaceae/Lactobacillus and decreased Clostridiaceae/Clostridium in HFD-fed mice. There was no effect of increasing the P/C ratio on energy intake, but the highest ratio reduced HFD-induced weight gain, fat mass and plasma triacylglycerol, non-esterified fatty acids, glucose and leptin levels, while it increased lean mass and oxygen consumption. Similar effects were observed on adipose mRNA expression, where the highest ratio reduced HFD-associated expression of UCP-2, TNFa and CD68 and increased the diet-associated expression of b3-AR, LPL, IR, IRS-1 and GLUT4. The P/C ratio also impacted on gut microbiota, with populations in the 30/ 40% WPI groups clustering together and away from the 20% WPI group. Taken together, our data show that increasing the P/C ratio has a dramatic effect on energy balance and the composition of gut microbiota, which is distinct from that caused by changes to protein quality.KN is supported by the Teagasc Vision Programme on Obesity, which also funded the work detailed in this manuscript. LM is supported by a Teagasc PhD Walsh Fellowship. HMR is supported by SFI PI (11/PI/1119)