Shake, rattle, \u27n\u27 roll: The representation of motion in language and cognition

Languages vary strikingly in how they encode motion events. In some languages (e.g. English), manner of motion is typically encoded within the verb, while direction of motion information appears in modifiers. In other languages (e.g. Greek), the verb usually encodes the direction of motion, while the manner information is encoded in modifiers. We designed two studies to investigate whether these language-specific patterns affect speakers’ reasoning about motion. We compared the performance of English and Greek children and adults (a) in non-linguistic (memory and categorization) tasks involving motion events, and (b) in their linguistic descriptions of these same motion events. Even though the two linguistic groups differed significantly in terms of their linguistic preferences, their performance in the non-linguistic tasks was identical. More surprisingly, the linguistic descriptions given by subjects within language also failed to correlate consistently with their memory and categorization performance in the relevant regards. For the domain studied, these results are consistent with the view that conceptual development and organization are largely independent of language-specific labeling practices. The discussion emphasizes that the necessarily sketchy nature of speech assures that it will be at best a crude index of thought

Exploring the role of empathy in social enterprise

An exploration into why communities cooperate and what enables us to take another person’s perspective into account transpires as valuable for social development and crucial in many situations in everyday life. The root definition of empathy, a term coined in 1858 by Rudolf Lotze based on a translation of the Greek term: empatheia, defines empathy as an ability to recognise oneself in another. Simply put, empathy is the experience of putting oneself in the shoes of somebody else. Multi-disciplinary interest in empathy provides a rich source of prior literature from where to begin to explore the under-researched role of empathy in Social Enterprise (SE). SE is increasingly recognised as an important contributor to societal and/or environmental regeneration through its pursuit of a social and/or environmental mission. In tackling social inequalities and unmet need, SEs address social problems in entrepreneurial and innovative ways. Inherent to SE is the need to connect and work with others in a much more collaborative way to traditional business, given that the beneficiaries of a SE are the central focus of the social mission and also valuable stakeholders. In working together a sense of reciprocal benefit is shared between the SE and its beneficiaries. The fieldwork took the form of a five month ethnography within one SE based in London. The organisation was established in the 1980s and has grown from a small workforce to now employ approximately one thousand people. The results of the research offer contributions to theory combined with practice, as the ethnographic methods provided the researcher with an opportunity to explore what is said about SE and what is done, in practice. The current research emphasises the connected nature of people and the dependence people have on one another, and this dependence is particularly related to SE. Emergent findings suggest empathy is like a ‘currency’ in SE. The SE and beneficiaries are as reliant on each other to achieve the collective social mission. Empathy emerges as vital for working together with a range of stakeholders, for the purpose of sharing viewpoints and creating welcomed services in the community. Furthermore, empathy emerges as a key contributor in sharing perspectives, motivating action for collective ends and striving for joint goals

Social Enterprise in the United Kingdom: Models and Trajectories

This paper begins by describing (in part A) the UK concept of social enterprise and how it is operationalised (section A.1); this is followed by an overview of the challenges of estimating the population of social enterprise in the UK, despite or because of different government-sponsored surveys (section A.2); this first part concludes with a review of the evolution of policy discourse for social enterprise (section A.3). The second part of the paper goes on to describe (sections B.1 to B.4) the different models that have evolved from different origins in the UK (with the main emphasis being on experience in England); in order to contextualise an understanding of these models, it describes three fields (section B.5)—work integration, community development, and public services; these illustrate the fluidity of models in the UK, where typically different models may be found within each field. Finally, Part C describes at a general level the relevant institutional frameworks and trajectories of the main social enterprise models

OUTdoor Swimming as a nature-based Intervention for DEpression (OUTSIDE): study protocol for a feasibility randomised control trial comparing an outdoor swimming intervention to usual care for adults experiencing mild to moderate symptoms of depression

Background Depression is common and the prevalence increasing worldwide; at least 1 in 10 people will experience depression in their lifetime. It is associated with economic costs at the individual, healthcare and societal level. Recommended treatments include medication and psychological therapies. However, given the long waiting times, and sometimes poor concordance and engagement with these treatments, a greater range of approaches are needed. Evidence for the potential of outdoor swimming as an intervention to support recovery from depression is emerging, but randomised controlled trials (RCTs) evaluating clinical and cost-effectiveness are lacking. This study seeks to investigate the feasibility of conducting a definitive superiority RCT, comparing an 8-session outdoor swimming course offered in addition to usual care compared to usual care only, in adults who are experiencing mild to moderate symptoms of depression. Feasibility questions will examine recruitment and retention rates, acceptability of randomisation and measures, and identify the primary outcome measure that will inform the sample size calculation for a definitive full-scale RCT. This study will also explore potential facilitators and barriers of participation through evaluation questionnaires, focus-group discussions and interviews. Methods/design To address these aims and objectives, a feasibility superiority RCT with 1:1 allocation will be undertaken. We will recruit 88 participants with mild to moderate symptoms of depression through social prescribing organisations and social media in three sites in England. Participants will be randomised to either (1) intervention (8-session outdoor swimming course) plus usual care or (2) usual care only. Both groups will be followed up for a further 8 weeks. Discussion If findings from this feasibility RCT are favourable, a fully powered RCT will be conducted to investigate the clinical- and cost-effectiveness of the intervention. Findings from the definitive trial will provide evidence about outdoor swimming for depression for policymakers and has the potential to lead to greater choice of interventions for adults experiencing symptoms of depression. Trial registration Current controlled trial registration number is ISRCTN 90851983 registered on 19 May 2022

Gridmapping the northern plains of Mars: Geomorphological, Radar and Water-Equivalent Hydrogen results from Arcadia Plantia

A project of mapping ice-related landforms was undertaken to understand the role of sub-surface ice in the northern plains. This work is the first continuous regional mapping from CTX (“ConTeXt Camera”, 6 m/pixel; Malin et al., 2007) imagery in Arcadia Planitia along a strip 300 km across stretching from 30°N to 80°N centred on the 170° West line of longitude. The distribution and morphotypes of these landforms were used to understand the permafrost cryolithology. The mantled and textured signatures occur almost ubiquitously between 35° N and 78° N and have a positive spatial correlation with inferred ice stability based on thermal modelling, neutron spectroscopy and radar data. The degradational features into the LDM (Latitude Dependent Mantle) include pits, scallops and 100 m polygons and provide supporting evidence for sub-surface ice and volatile loss between 35-70° N in Arcadia with the mantle between 70-78° N appearing much more intact. Pitted terrain appears to be much more pervasive in Arcadia than in Acidalia and Utopia suggesting that the Arcadia study area had more wide-spread near-surface sub-surface ice, and thus was more susceptible to pitting, or that the ice was less well-buried by sediments. Correlations with ice stability models suggest that lack of pits north of 65-70° N could indicate a relatively young age (~1Ma), however this could also be explained through regional variations in degradation rates. The deposition of the LDM is consistent with an airfall hypothesis however there appears to be substantial evidence for fluvial processes in southern Arcadia with older, underlying processes being equally dominant with the LDM and degradation thereof in shaping the landscape

Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors:a systematic review

Background: A precision medicine approach in type 2 diabetes requires the identification of clinical and biological features that are reproducibly associated with differences in clinical outcomes with specific anti-hyperglycaemic therapies. Robust evidence of such treatment effect heterogeneity could support more individualized clinical decisions on optimal type 2 diabetes therapy.Methods: We performed a pre-registered systematic review of meta-analysis studies, randomized control trials, and observational studies evaluating clinical and biological features associated with heterogenous treatment effects for SGLT2-inhibitor and GLP1-receptor agonist therapies, considering glycaemic, cardiovascular, and renal outcomes. After screening 5,686 studies, we included 101 studies of SGLT2-inhibitors and 75 studies of GLP1-receptor agonists in the final systematic review.Results: Here we show that the majority of included papers have methodological limitations precluding robust assessment of treatment effect heterogeneity. For SGLT2-inhibitors, multiple observational studies suggest lower renal function as a predictor of lesser glycaemic response, while markers of reduced insulin secretion predict lesser glycaemic response with GLP1-receptor agonists. For both therapies, multiple post-hoc analyses of randomized control trials (including trial meta-analysis) identify minimal clinically relevant treatment effect heterogeneity for cardiovascular and renal outcomes.Conclusions: Current evidence on treatment effect heterogeneity for SGLT2-inhibitor and GLP1-receptor agonist therapies is limited, likely reflecting the methodological limitations of published studies. Robust and appropriately powered studies are required to understand type 2 diabetes treatment effect heterogeneity and evaluate the potential for precision medicine to inform future clinical care.</p

Communicating Results of a Dietary Exposure Study Following Consumption of Traditionally Smoked Salmon

One expectation of community-based participatory research (CBPR) is participant access to study results. However, reporting experimental data produced by studies involving biological measurements in the absence of clinical relevance can be challenging to scientists and participants. We applied best practices in data sharing to report the results of a study designed to explore polycyclic aromatic hydrocarbons (PAHs) absorption, metabolism, and excretion following consumption of traditionally-smoked salmon by members of the Confederated Tribes of the Umatilla Indian Reservation (CTUIR). A dietary exposure study was developed, wherein 9 Tribal members consumed 50 grams of traditionally-smoked salmon and provided repeated urine samples over 24 hours. During recruitment, participants requested access to their data following analysis. Disclosing data is an important element of community-based participatory research, and must be treated with the same rigor as that given to the data analysis. The field of data disclosure is relatively new, but when handled correctly can improve education within the community, reduce distrust and enhance environmental health literacy. Using the results from this study, we suggest mechanisms for sharing data with a Tribal community.This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Mary Ann Liebert, Inc., and can be found at: http://www.liebertpub.com/overview/environmental-justice/259