Domain-adaptive deep network compression

Deep Neural Networks trained on large datasets can be easily transferred to new domains with far fewer labeled examples by a process called fine-tuning. This has the advantage that representations learned in the large source domain can be exploited on smaller target domains. However, networks designed to be optimal for the source task are often prohibitively large for the target task. In this work we address the compression of networks after domain transfer. We focus on compression algorithms based on low-rank matrix decomposition. Existing methods base compression solely on learned network weights and ignore the statistics of network activations. We show that domain transfer leads to large shifts in network activations and that it is desirable to take this into account when compressing. We demonstrate that considering activation statistics when compressing weights leads to a rank-constrained regression problem with a closed-form solution. Because our method takes into account the target domain, it can more optimally remove the redundancy in the weights. Experiments show that our Domain Adaptive Low Rank (DALR) method significantly outperforms existing low-rank compression techniques. With our approach, the fc6 layer of VGG19 can be compressed more than 4x more than using truncated SVD alone -- with only a minor or no loss in accuracy. When applied to domain-transferred networks it allows for compression down to only 5-20% of the original number of parameters with only a minor drop in performance.Comment: Accepted at ICCV 201

LIUM-CVC Submissions for WMT17 Multimodal Translation Task

This paper describes the monomodal and multimodal Neural Machine Translation systems developed by LIUM and CVC for WMT17 Shared Task on Multimodal Translation. We mainly explored two multimodal architectures where either global visual features or convolutional feature maps are integrated in order to benefit from visual context. Our final systems ranked first for both En-De and En-Fr language pairs according to the automatic evaluation metrics METEOR and BLEU.Comment: MMT System Description Paper for WMT1

Circulating PCSK9 levels and CETP plasma activity are independently associated in patients with metabolic diseases

Additional file 1: Figure S1. Correlations between CETP activity and CETP mass (A) and between PCSK9 and CETP mass (B) in patients with T2DM (n=30). CETP mass was measured in human serum using a quantitative enzyme-linked immunosorbent assay (ELISA) (American Diagnostica Gmbh). Spearman coefficients and P values are shown

Rotate your Networks: Better Weight Consolidation and Less Catastrophic Forgetting

In this paper we propose an approach to avoiding catastrophic forgetting in sequential task learning scenarios. Our technique is based on a network reparameterization that approximately diagonalizes the Fisher Information Matrix of the network parameters. This reparameterization takes the form of a factorized rotation of parameter space which, when used in conjunction with Elastic Weight Consolidation (which assumes a diagonal Fisher Information Matrix), leads to significantly better performance on lifelong learning of sequential tasks. Experimental results on the MNIST, CIFAR-100, CUB-200 and Stanford-40 datasets demonstrate that we significantly improve the results of standard elastic weight consolidation, and that we obtain competitive results when compared to other state-of-the-art in lifelong learning without forgetting.Comment: Accepted at ICPR'18. First two authors contributed equall

The CNIC-Polypill reduces recurrent major cardiovascular events in real-life secondary prevention patients in Spain: The NEPTUNO study.

To evaluate the effectiveness of a cardiovascular polypill including aspirin, ramipril and atorvastatin (CNIC-Polypill), on the incidence of recurrent major cardiovascular events (MACE) and risk factor control in patients with established atherosclerotic cardiovascular disease (ASCVD) vs different pharmacological therapeutic strategies. Retrospective, observational study using data from electronic-health records. Patients were distributed into 4 different cohorts: CNIC-Polypill (case cohort) vs 3 control cohorts: same monocomponents taken separately (Monocomponents), equipotent drugs (Equipotent) and other drugs not included in the previous cohorts (Other therapies). Patients were followed for 2 years or until MACE or death. After propensity score matching, a total of 6456 patients (1614 patients per cohort) were analysed. After 2 years, the risk of recurrent MACE was lower in the CNIC-Polypill cohort compared to the control groups (22%; p = 0.017, 25%; p = 0.002, 27%; p = 0.001, higher in the Monocomponents, Equipotent and Other therapies cohorts, respectively). The incremental proportion of patients who achieved blood pressure (BP) and low-density lipoprotein cholesterol (LDLc) control from baseline was higher in the CNIC-Polypill cohort vs control cohorts (BP controlled patients: +12.5% vs + 6.3%; p < 0.05, +2.2%; p < 0.01, +2.4%; p < 0.01, LDLc controlled patients: +10.3% vs + 4.9%; p < 0.001, +5.7%; p < 0.001, +4.9%; p < 0.001, respectively). Medication persistence was higher in patients treated with the CNIC-Polypill (72.1% vs 62.2%, 60.0% and 54.2%, respectively; p < 0.001) at study end. In secondary prevention patients, compared with control groups, treatment with the CNIC-Polypill was associated with significant reductions in the accumulated incidence of recurrent MACE, improved BP and LDLc control rates, and increased medication persistence.FerrerS

Salud sexual de las personas con discapacidad física: educación sexual

People with disabilities are often excluded from the social construct of functionality and sexual satisfaction, due to the existence of certain negative sexual stereotypes that usually have more serious psychosocial effects than the disability itself. Knowledge is necessary so that the professional, parental and/or social environment does not trivialize or ignore their sexuality.General aim: To provide information on sexual education for people with physical disabilities in Catalonia.Study design: Exploratory, descriptive and cross-sectional study.Sample: 135 surveys from subjects aged over 18 years with physical disability Instrumentation: Sexual Health Survey for People with Physical Disability ESSPDF / 2016.Outcomes: The preliminary results of the sexual education section are presented. 43% of the sample rated the degree of usefulness of the sexual information received as “Very useful/useful” and 9.6% had not received any information. 63% valued the information they had as “Very good/good”.There are significant differences in relation to gender on who would have chosen to receive sexual information (p=0.034), interest to obtain more information on topics such as “receiving information about prostitution” (p=0.01), “love and relationships” (p smaller than 0.001) and the sex of the person they would like to receiveadvise (p=0.014). They showed the greatest interest in topics such as “Ways to get and receive pleasure” and “problems in sexual relationships”.Conclusions: People with physical disabilities still have deficiencies in relation to sexual information. This situation requires the revision of the existing training and intervention programs, aswell as checking the accessibility of the services. It is necessary to work from all existing sex education areas, beyond the health field, such as family, school and society. Sex education should be opened to behavioral and sentimental aspects, thus improving the sexual health intervention of people with physical disabilities.Las personas con discapacidad a menudo quedan excluidas del constructo social de funcionalidad y satisfacción sexual, debido a la existencia de ciertos estereotipos sexuales negativos que suelen tener efectos psicosociales más graves que la propia discapacidad. Son necesarios determinados conocimientos para que el entorno profesional, parental y/o social no trivialice o ignore su sexualidad.Objetivo general: Aportar información en relación a la educación sexual de las personas condiscapacidad física en Cataluña.Diseño: Estudio exploratorio, descriptivo y transversal.Muestra: 135 encuestas de sujetos mayores de 18 años con discapacidad físicaInstrumentación: Encuesta de Salud Sexual para Personas con Discapacidad Física ESSPDF/2016.Resultados: Se presentan los resultados preliminares del apartado de educación sexual. El 43% de la muestra valoran el grado de utilidad de la información sexual recibida como “Muy útil/útil” y el 9,6% no había recibido ninguna información. El 63% consideran como “Muy buena/buena” la información que ahora disponen. Existen diferencias significativas en relación al sexo sobre quién habrían elegido para recibir información sexual (p=0.034), interés para obtener más información en temas como recibir información sobre “prostitución” (p=0.01), “amor y relaciones sentimentales” (p menor que 0.001) y el las mujeres preferían ser asesoradas por una mujer (p=0.014). El mayor interés se mostró en temas como “Maneras de obtener y recibir placer” y “problemas en las relaciones sexuales”.Conclusiones: Las personas con discapacidad física todavía tienen carencias en relación a la información sexual; esta situación requiere la revisión de los programas de formación e interven ción existentes, así como comprobar la accesibilidad a los servicios. Es necesario trabajar desde todos los entornos educadores sexuales existentes, más allá del ámbito sanitario, como es la familia, la escuela y la sociedad. Se debe abrir la educación sexual a aspectos conductuales y sentimentales, mejorando así la intervención en salud sexual de las personas con discapacidad físic

Whole-Genome Sequencing Applied to the Molecular Epidemiology of Shiga Toxin-Producing Escherichia coli O157:H7 in Argentina

Shiga toxin-producing Escherichia coli strains are worldwide associated with sporadic human infections and outbreaks. In this work, we report the availability of high-quality draft whole-genome sequences for 19 O157:H7 strains isolated in Argentina.Fil: Masana, Marcelo Oscar. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Tecnología de Alimentos; Argentina.Fil: Carbonari, Claudia Carolina. Instituto Nacional de Enfermedades Infecciosas-ANLIS ‘‘Dr. Carlos G. Malbrán’’. Servicio Fisiopatogenia; Argentina.Fil: Fittipaldi, Nahuel. Public Health Ontario. Toronto Laboratories; Canada. University of Toronto. Department of Laboratory Medicine and Pathobiology; Canada.Fil: Teatero, Sarah. Public Health Ontario. Toronto Laboratories; Canada.Fil: Athey, Taryn B. T. Public Health Ontario. Toronto Laboratories; Canada.Fil: Pianciola, Luis. Subsecretaría de Salud de Neuquén. Laboratorio Central; Argentina.Fil: Melano, Roberto G. Public Health Ontario. Toronto Laboratories; Canada. University of Toronto. Department of Laboratory Medicine and Pathobiology; Canada.Fil: Rivas, Marta. Instituto Nacional de Enfermedades Infecciosas-ANLIS ‘‘Dr. Carlos G. Malbrán’’. Servicio Fisiopatogenia; Argentina.Fil: Chinen, Isabel. Instituto Nacional de Enfermedades Infecciosas-ANLIS ‘‘Dr. Carlos G. Malbrán’’. Servicio Fisiopatogenia; Argentina

Resultados preliminares del estudio paleosísmico mediante trincheras de la falla de Alhama de Murcia (Cordillera Bética)

Trenching on Alhama de Murcia fault trace has been done in order to identify and quantify paleoseismic deformation on a 100 km long active oblique-slip fault. The first results from one of the trenches confirm the existence of coseism ic reverse fault deformation affecting quaternary alluvial fan deposits. The sedimentary evolution observed on trench shows a temporary blocking of Colmenar creek flow (in the foot wall of the Alhama de Murcia fault), due to uplifting of the hanging wall during coseismic reactivation. An available age of 3010 ± 90 yr post-dated that process